Clinical trials: Hyperbaric
Elective Caesarean Section
Sequential Intrathecal Injection of Fentanyl and Hyperbaric Bupivacaine
56 Parturients, aged 18-40 year, undergoing elective CS were randomly assigned to receive sequential intrathecal injection of fentanyl and hyperbaric bupivacaine at the same rate (normal sequential) NS or a rapid intrathecal…
- Trial name
- NCT03415087
- Testing
- sequential intrathecal injection, hyperbaric bupivacaine, fentanyl
- Volunteers
- 56 people
- Sponsor
- Ain Shams University
Chronic Pain, Complex Regional Pain Syndrome
Hyperbaric Oxygen Therapy in Complex Regional Pain Syndrome
The aim of the study is to investigate the efficacy of hyperbaric oxygen therapy as an adjunct in the management of severe complex regional pain syndrome.
- Trial name
- NCT07446712
- Testing
- Early hyperbaric oxygen therapy (HBOT), Delayed hyperbaric oxygen therapy (HBOT)
- Where
- 2 sites in Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Ostrava
Fibrosis
Treatment of Radiation-induced Fibrosis in the Upper Aerodigestive Tract Cancer by a Combination of Pentoxifylline-tocopherol and Hyperbaric Oxygen
The pentoxifylline used with tocopherol achieves a certain effectiveness in the treatment of the fibrosis. Hyperbaric oxygen therapy has been recommended and used in a wide variety of medical conditions including the treatment of…
- Trial name
- ORT-OXI-2009 (NCT01822405)
- Testing
- pentoxifylline with tocopherol, pentoxifylline+tocopherol + Hyperbaric Oxygen Therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitario de Canarias
Infectious Endocarditis
Hyperbaric Oxygen Treatment in Humans With Gram Positive Cocci Endocarditis
Infectious endocarditis (IE) is defined as an infection anywhere on the endocardium, most often localised to the cardiac valves. It is an infection with an increasing incidence and in Denmark with 6-700 new cases annually.
- Trial name
- ENDOHOT (NCT04691440)
- Testing
- Hyperbaric oxygen
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Ole Hyldegaard
Analgesia
Comparison of Meperidine and Sufentanil Added to 0.5% Hyperbaric Bupivacaine for Spinal Anesthesia in Cesarean Section
Subarachnoid block is a widely used anesthetic technique for cesarean section. To improve the quality of analgesia and prolong its duration, the addition of intrathecal opioids to local anesthetics has been encouraged.
- Trial name
- NCT04446715
- Testing
- sufentanil, meperidine, Bupivacaine
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Avascular Necrosis of Femur Head
Investigation of the Effect of Hyperbaric Oxygen Therapy in Patients With Avascular Necrosis
Avascular necrosis is a condition that occurs when bone tissue loses sufficient blood flow. This condition causes bone cells to die and, as a result, bone structure to deteriorate.
- Trial name
- NCT07142018
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Autism Spectrum Disorder
Study to Compare Verbal Scores of Children Diagnosed With ASD Who Received Hyperbaric Treatment To Those Who Did Not
A child's ability to effectively communicate with peers, parents, and caregivers impacts their level of independence and quality of personal relationships.
- Trial name
- NCT06043284
- Testing
- Hyperbaric Oxygen Therapy
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Oxford Recovery Center
Complications; Cesarean Section, Hypotension
Extra Sitting Time After Spinal Anesthesia for Cesarean Section and Fetal Well-being
After injection of the spinal anesthetic drug, women will be allowed to lie down immediately (0-30 sec) or after three minutes (180 sec) of sitting.
- Trial name
- NCT02893696
- Testing
- Various sitting time
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Hyperbaric Oxygen Therapy, Carbon Monoxide Poisoning
Optimal Number of Hyperbaric Oxygen Treatments for Carbon Monoxide Poisoning
The optimal treatment strategy with hyperbaric oxygen therapy has been the subject of some debate over the past 3 decades. Initial landmark studies showed a decrease in the incidence of DNS with a single treatment and also with…
- Trial name
- NCT06619717
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Alberta
Chronic Renal Failure
Hyperbaric Oxygen Therapy for Renal Regeneration in Diabetic Nephropathy
Diabetes kidney disease is a leading cause for end stage renal disease in the western world. To date no treatment that can reverse renal damage exists.
- Trial name
- NCT03376282
- Testing
- Hyperbaric Oxygen oxygen therapy (HBOT)
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Assaf-Harofeh Medical Center
Traumatic Injury of the Spinal Cord
Hyperbaric Oxygenation (HBO) in Traumatic Spinal Cord Injury. (EOS) - Pilot Study
Hypothesis of the Study: Based on the presented results, the investigator hypothesises that HBO preserves neurons that are not irreversibly damaged (i.e. severed) during initial trauma, thus enabling regain of their function.
- Trial name
- NCT03101982
- Testing
- HBO
- Where
- Austria
- Volunteers
- 11 people
- Sponsor
- Medical University of Graz
Type 2-diabetes
Acute Hyperbaric Oxygen Treatment Increases Hepatic Insulin Sensitivity and Muscle Reactive Oxygen Species in T2D
Diabetes mellitus type 2 (T2D) is characterized by insulin resistance of liver and skeletal muscle, which is at least partly due to impaired muscle mitochondrial function.
- Trial name
- NCT04219215
- Testing
- 100% O2 in oxygen chamber, 21% O2 in oxygen chamber
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- German Diabetes Center
Breast Cancer, Lymphedema
Hyperbaric Oxygen Therapy Compared With Standard Therapy in Treating Chronic Arm Lymphedema in Patients Who Have Undergone Radiation Therapy for Cancer
RATIONALE: Hyperbaric oxygen therapy may be effective in repairing damaged tissue and reducing lymphedema caused by radiation therapy for cancer.
- Conditions
- Breast Cancer, Lymphedema, Perioperative/Postoperative Complications, Radiation Fibrosis
- Trial name
- NCT00077090
- Testing
- hyperbaric oxygen
- Where
- 5 sites in United Kingdom
- Volunteers
- 63 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Post-Concussion Syndrome
Hyperbaric Oxygen Therapy for Post-Concussion Syndrome
The purpose of this study is to decrease symptom burden, improve cognitive function, and improve quality of life outcomes in subjects with mild TBI and persisting post-concussion syndrome using Hyperbaric Oxygen Treatment…
- Trial name
- NCT05643482
- Testing
- Hyperbaric Oxygen Treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Texas Southwestern Medical Center
Traumatic Brain Injury (TBI) Patients, Post Concussive Symptoms
Hyperbaric Oxygen Therapy for Veterans With TBI and PCS: A Biomarker Study
The goal of this study is to examine changes in blood biomarkers following hyperbaric oxygen therapy (HBOT) in military veterans with traumatic brain injury and persistent post-concussive symptoms.
- Conditions
- Traumatic Brain Injury (TBI) Patients, Post Concussive Symptoms, PTSD
- Trial name
- NCT07849465
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Summit Hyperbarics and Wellness
Breast Cancers
A Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Hormone Receptor Positive Breast Cancer Patients
The goal of this study is to explore the efficacy and safety of hyperbaric oxygen in the neoadjuvant treatment of hormone receptor positive breast cancer patients
- Trial name
- NCT06825949
- Testing
- Hyperbaric oxygen treatment
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Guangdong Provincial People's Hospital
Pregnant Women, Pain
Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia
Over the past 15 years, cesarean delivery is most commonly performed under spinal anesthesia using hyperbaric bupivacaine which provides an adequate sensory and motor block.
- Conditions
- Pregnant Women, Pain, Hypotension
- Trial name
- NCT02973048
- Testing
- Hyperbaric bupivacaine, Hyperbaric prilocaine
- Where
- 2 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Laryngeal Cancer
Efficacy of Hyperbaric Oxygen Therapy in Laryngectomy Patients
This study is designed to develop a predictive model for the development of wound complications in patients undergoing laryngectomy surgery for laryngeal/adjoining structure cancers, and to evaluate the clinical efficacy of…
- Trial name
- NCT00026975
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Hyperbaric Oxygen Therapy, Mild Cognitive Impairment
MRI Brain Changes Induced by Hyperbaric Oxygen Therapy in Brain Injury Patients
In our institute there is ongoing treatment of brain injury patients with Hyperbaric oxygen therapy. These patients undergo neuro-cognitive function tests in addition to brain imaging studies before and after treatment.
- Trial name
- NCT02452619
- Testing
- Hyperbaric oxygen therapy
- Where
- 2 sites in Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Wounds and Injuries
Tissue Perfusion and Blood Flow Monitoring Technology
The purpose of this study is to investigate the safety and efficacy of an optical device designed and developed to quantitatively monitor blood flow velocity of wound sites.
- Trial name
- WoundImager (NCT01139567)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- CW Optics, Inc.