Clinical trials: Hyperbaric
AVN
Hyperbaric Oxygen Therapy Versus Core Decompression Augmented With Bone Substitute in Pre Collapse of Avascular Necrosis of Femoral Head
Introduction: osteonecrosis of the femoral head is a potentially crippling disorder, which mainly affects the young adults. Core decompression has been used for the treatment of the osteonecrosis of the femur head since was…
- Trial name
- NCT04657653
- Testing
- core decompression
- Where
- Qatar
- Volunteers
- 19 people
- Sponsor
- Hamad Medical Corporation
Hyperbaric Oxygen Therapy, Middle Ear Barotrauma
Effect of Self-acupressure on Middle Ear Barotrauma Associated With Hyperbaric Oxygen Therapy
Middle ear barotrauma (MEB) is the most common complication during hyperbaric oxygen therapy (HBOT). Though Valsalva and Toynbee maneuvers have been proposed to prevent MEB, still some patients discontinue HBOT due to severe…
- Trial name
- NCT04311437
- Testing
- Self-acupressure therapy, Combined Valsalva and Toynbee maneuvers
- Where
- Taiwan
- Volunteers
- 152 people
- Sponsor
- Chang Gung Memorial Hospital
Osteoradionecrosis, Osteoradionecrosis of Jaw
Combination Therapy: Hyperbaric Oxygen and PENTOCLO for Treatment of Osteoradionecrosis of the Mandible
Radiation is commonly used to treat cancer in the head and neck, however, this can lead to a serious complication called osteoradionecrosis (ORN), where there is necrotic (dead) open bone inside or outside of the mouth.
- Conditions
- Osteoradionecrosis, Osteoradionecrosis of Jaw, Osteoradionecrosis of the Mandible
- Trial name
- NCT06055257
- Testing
- modified PENTOCLO (mPENTOCLO)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
Vaso-occlusive Crisis, Sickle Cell Anemia Crisis
Hyperbaric Oxygen Therapy in Sickle Cell Pain
Sickle cell anemia is a genetic blood disorder where red blood cells are abnormally shaped, crescent- or sickle-shaped, instead of the normal, round shape.
- Trial name
- HAVOC (NCT03412045)
- Testing
- hyperbaric oxygen therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Nebraska
Post Cesarean Section Pain
Optimal Intrathecal Morphine Dose for Better Post Cesarean Section Analgesia
Central neuraxial blocks (CNBs) remain the preferred anesthetic technique for cesarean section, with single shot spinal anesthesia (SSSA) being the standard practice at investigator's institute unless contraindicated.
- Trial name
- Analgesia (NCT07560501)
- Testing
- 0.5% bupivacaine heavy with fentanyl, 0.5% bupivacaine heavy with fentanyl plus morphine 50 mcg, 0.5% bupivacaine heavy with fentanyl plus morphine100 mcg
- Volunteers
- 180 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Spinal for Caesarean Section
Effect of Prilocaine on Motor Block During Caesarean Section
To compare the effects of using intrathecal prilocaine combined with fentanyl on duration of motor block versus that of intrathecal bupivacaine combined with fentanyl in elective caesarean section.
- Trial name
- NCT06133881
- Testing
- prilocaine, bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Diabetic Foot Ulcer
Effectiveness of Diabetic Recovery Shoes and Artificial Intelligence Supported Structured Exercise Program
This study aims to evaluate the effectiveness of the diabetic recovery sandal and artificial intelligence supported structured exercise program in individuals diagnosed with diabetic foot receiving hyperbaric oxygen therapy.
- Trial name
- NCT06515665
- Testing
- therapeutic foot orthosis
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hacettepe University
Focus: Healthy Adults Without Brain Injury
Normative Datasets for Assessments Planned for Mild Traumatic Brain Injury (NORMAL)
The purpose of the research study is to collect information about brain function and structure among active duty military personnel or civilians who are healthy.
- Trial name
- NORMAL (NCT01925963)
- Where
- 2 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Lindell Weaver
Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy
Treatment of U.S. Veterans With Mild Traumatic Brain Injury With Hyperbaric Oxygen Therapy
Mild traumatic brain (mTBI) injury affects 400,000 U.S. Veterans resulting in physical, cognitive and mental health symptoms. The Department of Defense (DoD) reported 26 suicides a day from mTBI despite ongoing care for the…
- Conditions
- Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy, Depression
- Trial name
- NCT06665633
- Testing
- Oxygen 100 % Gas for Inhalation, Hyperbaric Oxygen Therapy Chamber
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nova Southeastern University
Breast Cancers
Hyperbaric Oxygen Therapy for Peripheral Neuropathy Due to Paclitaxel Analogs
The goal of this study was to explore the safety and efficacy of hyperbaric oxygen in the treatment of peripheral neuropathy due to paclitaxel analogues
- Trial name
- NCT06819501
- Testing
- hyperbaric oxygenation treatment, routine care
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Guangdong Provincial People's Hospital
Diabetic Peripheral Neuropathic Pain (DPN)
Hyperbaric Oxygen Therapy Versus High Power Laser for Diabetic Neuropathy
The purpose of this study is to compare the clinical effects of Hyperbaric Oxygen Therapy (HBOT) versus High-Intensity Laser Therapy (HPLT) on sensorimotor functions and nerve conduction in patients suffering from painful…
- Trial name
- HBOT-HPLT-DPN (NCT07848867)
- Testing
- Conventional Physiotherapy Program, Hyperbaric Oxygen Therapy, High-Intensity Laser Therapy
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Neurological Impairments, Leukoencephalopathies
Hyperbaric Oxygen Treatment in Patients With White Matter Hyperintensities
The primary purpose of this study is to assess whether hyperbaric oxygen treatment improves neurological function in patients who exhibit white matter hyperintensities on MRI examination.
- Trial name
- NCT00497432
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- St. Luke's Hospital, Chesterfield, Missouri
Elective Caesarean Section
Sequential Intrathecal Injection of Fentanyl and Hyperbaric Bupivacaine
56 Parturients, aged 18-40 year, undergoing elective CS were randomly assigned to receive sequential intrathecal injection of fentanyl and hyperbaric bupivacaine at the same rate (normal sequential) NS or a rapid intrathecal…
- Trial name
- NCT03415087
- Testing
- sequential intrathecal injection, hyperbaric bupivacaine, fentanyl
- Volunteers
- 56 people
- Sponsor
- Ain Shams University
Obesity, Type 2 Diabetes
Hyperbaric Oxygen Treatment Ameliorates Insulin Resistance
Obesity is an epidemic in Western society and is the biggest risk factor for insulin resistance and type 2 diabetes. The investigators have preliminary evidence showing that hyperbaric oxygen therapy rapidly increases insulin…
- Trial name
- HOTAIR (NCT01361971)
- Testing
- Hyperbaric Oxygen Treatment
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Aging
A Dosing Study of Hyperbaric Oxygen Therapy (HBOT) on Epigenetic Aging
This study aims to assess the impact of hyperbaric oxygen therapy on a number of outcomes, including epigenetic aging, inflammation, and cellular health.
- Trial name
- HBOT (NCT05297019)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TruDiagnostic
Otitic Barotrauma
Inner and Middle Ear Effects of Hyperbaric Oxygen Thrapy
Audiological evaluation performed to patients on hyperbaric oxygen therapy to see its effects on middle ear pressure
- Trial name
- NCT04186741
- Testing
- Hyperbaric oxygen
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Brain and Central Nervous System Tumors
Radiation Therapy Plus Hyperbaric Oxygen in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Hyperbaric oxygen may increase the effectiveness of radiation therapy.
- Trial name
- NCT00006460
- Testing
- hyperbaric oxygen, radiation therapy
- Where
- United States
- Sponsor
- Barrett Cancer Center
Transurethral Resection of the Prostate (TURP)
Changes of Upper and Lower Limb Blood Flow and Vascular Resistance in Hyperbaric Spinal Anesthesia for Transurethral Resection of the Prostate (TURP) Using Duplex Ultrasonography: Comparison of Normotensive and Hypertensive Patients
Changes of Upper and Lower Limb Blood Flow and Vascular Resistance in Hyperbaric Spinal Anesthesia for TURP Using Duplex Ultrasonography: Comparison of Normotensive and Hypertensive Patients.
- Trial name
- NCT01091779
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Ulcerative Colitis
The Efficacy of Hyperbaric Oxygen-assisted Treatment for ASUC and Refractory IBD
The Department of Gastroenterology plans to conduct a randomized controlled study on the efficacy analysis of hyperbaric oxygen-assisted treatment for acute severe ulcerative colitis and refractory inflammatory bowel disease.
- Trial name
- NCT07257588
- Testing
- Administration of methylprednisolone sodium succinate, Hyperbaric Oxygen Therapy
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Covid19
Hyperbaric Oxygen for Long COVID-19 Pulmonary Sequela
This is a pilot study in 24 subjects where half will be randomized to 10 treatments with hyperbaric oxygen (HBO). It will primarily study pulmonary sequelae with imaging and physiological measurements (low dose chest computer…
- Trial name
- NCT04905888
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Sponsor
- Peter Lindholm