Clinical trials: Hyperbaric
Cardiovascular Fitness, Inflammation
Evaluating Whether Hyperbaric Oxygen Therapy Can Improve VO₂-Max and Reduce Inflammation Markers in Healthy Adults Ages 30-60.
The purpose of this study is to determine whether hyperbaric oxygen therapy (HBOT) at 1.75 atmospheres of pressure (ATA) improves cardiovascular fitness (VO₂ max) and reduces inflammation in healthy adults.
- Trial name
- NCT07361861
- Testing
- Hyperbaric Oxygen Therapy
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Chronic Neurological Deficiency, Stroke
Hyperbaric Oxygen Therapy Induced Neuroplasticity in Post Stroke Patients Suffering Chronic Neurological Deficiencies
The aim of the current work was to evaluate, for the first time in a prospective randomized study, the effect of HBOT on patients with chronic neurological deficiency due to stroke.
- Trial name
- NCT00715897
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- 2 sites in Israel
- Volunteers
- 74 people
- Sponsor
- Assaf-Harofeh Medical Center
Opioid Use Disorder
Hyperbaric Oxygen Treatment (HBOT) During Methadone Tapering
The aims of this study are to 1) explore the efficacy of hyperbaric oxygen therapy (HBOT) applied at two different pressures compared to sham treatment in relieving signs and symptoms (both physical and psychological) of opioid…
- Trial name
- NCT05924022
- Testing
- Hyperbaric Oxygen Treatment Full, Hyperbaric Oxygen Treatment Partial Pressure
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Washington State University
Post Spinal Shivering
Dexmedetomidine and Fentanyl As Adjuvants to Hyperbaric Bupivacaine for the Prevention of Post-spinal Shivering in Hip Arthroplasty Surgeries
The aim of this study is to compare the efficacy of intrathecal dexmedetomidine versus intrathecal fentanyl when added to hyperbaric bupivacaine in the prevention of post-spinal shivering in patients undergoing hip arthroplasty…
- Trial name
- NCT06834841
- Testing
- Dexmedetomidine, Fentanyl
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Coma, Carbon Monoxide Poisoning
Carbon Monoxide-induced Coma: Prognostic Factors
The primary objective of the study is to determine prognostic factors for hospital-mortality following carbon monoxide (CO)-induced coma.
- Trial name
- Coma-CO (NCT03926494)
- Where
- France
- Volunteers
- 212 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Evaluate Requirements of 2% Prilocaine in MR-UF Prostate Biopsy
ED50 of Intratecal Prilocaine in Ultrasound Fusion Prostate Biopsy
The aim of the present study was to determine the ED50 and ED90 of intrathecal hyperbaric 2% prilocaine (HP) for patients undergoing ambulatory prostate biopsy via magnetic resonance imaging (MRI)/ultrasound fusion.
- Trial name
- NCT05649020
- Testing
- Dose of prilocaine
- Where
- 2 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Post Low Grade Glioma Surgery, Cognitive Deficits
Hyperbaric Oxygen Therapy Can Improve Cognitive Deficits Post Low Grade Glioma Removal Surgery
The aim of the current study is to evaluate, in a prospective cross-over, randomized study, the effect of hyperbaric oxygen therapy (HBOT) on patients with chronic impairment after low grade glioma tumor removal surgery
- Trial name
- NCT02122042
- Testing
- HBOT
- Where
- Israel
- Volunteers
- 62 people
- Sponsor
- Assaf-Harofeh Medical Center
Hyperbaric Oxygenation, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Initiation Time in Acute Carbon Monoxide Poisoning
Hyperbaric oxygen therapy (HBO2) is recommended for symptomatic patients within 24 h of carbon monoxide (CO) poisoning. However, previous major studies found significantly better outcomes with HBO2 in patients treated within 6 h.
- Conditions
- Hyperbaric Oxygenation, Carbon Monoxide Poisoning, Time
- Trial name
- NCT04656912
- Testing
- Hyperbaric oxygen therapy
- Where
- South Korea
- Volunteers
- 706 people
- Sponsor
- Wonju Severance Christian Hospital
Wounds and Injuries
Tissue Perfusion and Blood Flow Monitoring Technology
The purpose of this study is to investigate the safety and efficacy of an optical device designed and developed to quantitatively monitor blood flow velocity of wound sites.
- Trial name
- WoundImager (NCT01139567)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- CW Optics, Inc.
Does Hyperbaric Chaber Treatment Improve Diabetic Retinopathy
The Effect of Hyperbaric Chamber Treatment on Patients With Diabetic Retinopathy
Diabetic retinopathy (DR) is a common complication of diabetes and is divided into non proliferative DR and proliferative DR. The damage is caused by either macular edema, macular ischemia that can be followed by vascular…
- Trial name
- NCT02235935
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Assaf-Harofeh Medical Center
Avascular Necrosis of Femur Head
Investigation of the Effect of Hyperbaric Oxygen Therapy in Patients With Avascular Necrosis
Avascular necrosis is a condition that occurs when bone tissue loses sufficient blood flow. This condition causes bone cells to die and, as a result, bone structure to deteriorate.
- Trial name
- NCT07142018
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Carbon Monoxide Poisoning
One vs. Three Hyperbaric Oxygen Treatments for Acute Carbon Monoxide Poisoning
This randomized trial will investigate important clinical outcomes of patients with acute carbon monoxide poisoning randomized to receive either one or three hyperbaric oxygen treatments.
- Trial name
- 1V3CORCT (NCT00465855)
- Testing
- Hyperbaric Oxygen (HBO2) - 3 sessions, Hyperbaric Oxygen (HBO2) - 1 session
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Intermountain Health Care, Inc.
This Study Was Focused on Selective Spinal Anesthesia for Lower Extremity Surgery in Order to Achieve Early Mobilization and to Shorten Hospital Stay
Hyperbaric Levobupivacaine for Spinal Anaesthesia
Spinal anaesthesia also called spinal block or sub-arachnoid block (SAB), is a form of regional anaesthesia involving injection of a local anaesthetic into the subarachnoid space, generally through a fine needle.
- Trial name
- NCT01938755
- Testing
- levobupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Ordu University
Acute Kidney Injury
Hyperbaric Oxygen Therapy and Acute Kidney Injury
Kidney injury is a serious complication of cardiac surgery that occurs in up to 30% of patients and increases the risk of adverse outcomes.
- Trial name
- NCT02743754
- Testing
- Standard therapy, Hyperbaric Oxygen
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- University Health Network, Toronto
Post Stroke Depression
Hyperbaric Oxygen Therapy for Persistent Post Stroke Depression
The study evaluates the effect of HBOT on depression in patients suffering from persistent symptoms of post stroke depression (PSD) in an double blind sham control study.
- Trial name
- NCT07423273
- Testing
- hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 142 people
- Sponsor
- Assaf-Harofeh Medical Center
Cerebral Decompression Illness, All Phases
Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Cerebral Decompression Illness
Chart review of patients who received hyperbaric oxygen therapy for cerebral decompression illness who also underwent SPECT brain blood flow imaging to see if SPECT brain imaging tracks and is consistent with the clinical…
- Trial name
- NCT02105194
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Paul G. Harch, M.D.
Traumatic Injury of the Spinal Cord
Hyperbaric Oxygenation (HBO) in Traumatic Spinal Cord Injury. (EOS) - Pilot Study
Hypothesis of the Study: Based on the presented results, the investigator hypothesises that HBO preserves neurons that are not irreversibly damaged (i.e. severed) during initial trauma, thus enabling regain of their function.
- Trial name
- NCT03101982
- Testing
- HBO
- Where
- Austria
- Volunteers
- 11 people
- Sponsor
- Medical University of Graz
Fibromyalgia, Chronic Pain
HBOT in Fibromyalgia
Fibromyalgia (FM) is a chronic pain condition affecting several millions of Canadians. Although the etiology and pathophysiology are poorly understood, there is a well-recognized association between muscular pain in fibromyalgia…
- Trial name
- NCT02467218
- Testing
- Hyperbaric Oxygen Treatment
- Where
- 2 sites in Canada
- Volunteers
- 16 people
- Sponsor
- University Health Network, Toronto
Spinal Anesthesia, Cesarean Section
Does the Addition of Epinephrine Prolong the Duration of Spinal Anesthesia for Repeat Cesarean Section?
The purpose of this study is to investigate whether the addition of a medication called epinephrine to spinal medications prolongs the duration of the anesthesia.
- Trial name
- NCT02369510
- Testing
- Low-dose epinephrine, High-dose epinephrine, No epinephrine
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Optic Neuropathy, Glaucoma
Hyperbaric Oxygen Therapy for Optic Neuropathies
The purpose of the study is to evaluate the neuroprotective efficacy of hyperbaric oxygen for the treatment in patients with optic neuropathy.
- Trial name
- HBOT (NCT06128720)
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University