Clinical trials: Hyperbaric
BRAIN MALIGNANCIES AFTER RADIATION THERAPY
Hyperbaric Oxygen Stimulation for Patients With Brain Malignancies After Radiation Therapy.
Radiotherapy is the mainstay of treatment for brain malignancies and is associated with significant neurotoxicity. Due to continuous increase in patient's survival, the long term risk for radiation-induced brain inflammation and…
- Trial name
- NCT01808625
- Testing
- HYPERBARIC OXYGEN STIMULATION
- Where
- Israel
- Volunteers
- 2 people
- Sponsor
- Sheba Medical Center
Post-concussive Symptoms, Traumatic Brain Injury
Hyperbaric Oxygen Therapy (HBO2) for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (mTBI)
This is a Phase II randomized trial designed to describe the magnitude of change between baseline and follow-up outcomes for symptom surveys and a battery of neuropsychological tests administered at time points corresponding…
- Trial name
- HOPPS (NCT01306968)
- Testing
- hyperbaric oxygen
- Where
- 5 sites in United States
- Volunteers
- 79 people
- Sponsor
- U.S. Army Medical Research and Development Command
Traumatic Brain Injury, Post-Concussive Symptoms
Long-Term Outcomes Following HBOT
This study is designed to better understand the long-term effects of hyperbaric oxygen therapy (HBOT). Our goal is to determine whether improvements after treatment are maintained over time and whether additional benefits appear…
- Conditions
- Traumatic Brain Injury, Post-Concussive Symptoms, Post-Traumatic Stress Disorder
- Trial name
- NCT07732374
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Summit Hyperbarics and Wellness
Hemondynamic Changes in Spinal Anesthesia
Comparison of Hemodynamic Effects of Bupivacaine in Spinal Anesthesia
To assess hemodynamic changes with hyperbaric bupivacaine with spinal anesthesia
- Trial name
- Nill (NCT07616882)
- Testing
- Spinal Anesthesia (bupivacaine)
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Liaquat National Hospital & Medical College
Decompression Sickness
Markers of Central Nervous System Injury in Decompression Sickness
Research hypothesis There is a correlation between the quantity of fluid markers of CNS injury in blood and DCS. There is a correlation between quantity and kind of fluid markers of CNS injury in blood and both diving profile and…
- Trial name
- DCS NEURO (NCT03192956)
- Testing
- No active intervention
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Sahlgrenska University Hospital
Aging
Angiogenesis Induced in the Elderly by Hyperbaric Oxygen Therapy
Recent studies show preliminary evidence of HBOT therapeutic effects on angiogenesis, increased tissue blood flow and oxygenation correlated with tissue function.
- Trial name
- ANGIOHBOT (NCT02790541)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Outpatients, General Surgery
Comparing the Effects of Levobupivacaine and Bupivacaine in Saddle Spinal Anesthesia
İn this study; it was aimed to investigate the effects of equipotent doses of hyperbaric bupivacaine and hyperbaric levobupivacaine in outpatient anorectal surgery under saddle block.
- Conditions
- Outpatients, General Surgery, Anorectal Disorder, Anesthesia
- Trial name
- NCT04245774
- Testing
- Levobupivacaine (as Levobupivacaine Hydrochloride) 75 Mg/10 mL Solution for Injection Ampoule, Bupivacaine/Dextrose
- Volunteers
- 60 people
- Sponsor
- Gazi University
Infectious Endocarditis
Hyperbaric Oxygen Treatment in Humans With Gram Positive Cocci Endocarditis
Infectious endocarditis (IE) is defined as an infection anywhere on the endocardium, most often localised to the cardiac valves. It is an infection with an increasing incidence and in Denmark with 6-700 new cases annually.
- Trial name
- ENDOHOT (NCT04691440)
- Testing
- Hyperbaric oxygen
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Ole Hyldegaard
Radiation Injury, Radiation-Induced Complications
Hyperbaric Oxygen Therapy for Treatment of Severe Radiation-Induced Complications
This study evaluates the safety and effectiveness of hyperbaric oxygen therapy (HBOT) for the treatment of severe radiation-induced complications in patients previously treated with radiotherapy.
- Conditions
- Radiation Injury, Radiation-Induced Complications, Radiation Necrosis
- Trial name
- NCT07422168
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- Slovenia
- Volunteers
- 39 people
- Sponsor
- Institute of Oncology Ljubljana
Secondary Hyperalgesia, Inflammation
The Effect of Hyperbaric Oxygen Therapy on Inflammatory Parameters Induced by a Heat Injury Model
Hyperbaric oxygen may reduce neurophatic pain and promote wound healing. Established anti inflammatory effects of HBO may contribute to this effect.
- Trial name
- HBO-SHA (NCT02397343)
- Testing
- Hyperbaric oxygen
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain, Obesity
Effect of Body Mass Index on the Dose of Intrathecal Hyperbaric Bupivacaine for Elective Cesarean Section
Combined spinal - epidural (CSE) anesthesia is a well established technique used for elective Cesarean section. As its name suggests, it combines two anesthesia techniques - spinal and epidural.
- Trial name
- NCT00403663
- Testing
- bupivacaine 0.75% with fentanyl and morphine
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Anesthesia, Obstetric Anesthesia Problems
Effect of Subarachnoid Hyperbaric Bupivacaine in Obese Pregnant Patients Undergoing Cesarean Section
Evaluates the effect of hyperbaric subarachnoid bupivacaine at doses of 5 mg vs 10 mg on mean arterial pressure in obese pregnant patients undergoing cesarean section
- Trial name
- NCT06060015
- Testing
- 5mg bupivacaine, 10mg bupivacaine
- Where
- Mexico
- Volunteers
- 106 people
- Sponsor
- Hospital Civil de Guadalajara
Hypoxic-ischemic Encephalopathy
Hyperbaric Oxygen Therapy Improves Outcome of Hypoxic-Ischemic Encephalopathy
The purpose of this study is to to evaluate the safety and efficacy of hyperbaric oxygen in term gestation newborn infants with hypoxic-ischemic encephalopathy..
- Trial name
- NCT02894866
- Testing
- hyperbaric oxygen
- Where
- 10 sites in China
- Volunteers
- 250 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Breast Cancers
A Phase II Single-Arm Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Breast Cancer Patients
The goal of the study is to explore the efficacy and safety of hyperbaric oxygen in the neoadjuvant treatment of breast cancer patients
- Trial name
- NCT06811870
- Testing
- hyperbaric oxygen treatment
- Where
- 2 sites in China
- Volunteers
- 161 people
- Sponsor
- Guangdong Provincial People's Hospital
Diabetes, Foot Ulcer
Hyperbaric Oxygen Therapy as Adjunctive Treatment of Chronic Diabetic Foot Ulcers
The purpose of this study is to evaluate if hyperbaric oxygen therapy heels more foot ulcers as compared to placebo in patients with diabetes mellitus and chronic foot ulcers.
- Conditions
- Diabetes, Foot Ulcer, Healing
- Trial name
- HODFU (NCT00953186)
- Testing
- hyperbaric air, HBOT
- Where
- Sweden
- Volunteers
- 94 people
- Sponsor
- Mrs. Thelma Zoegas Foundation
Traumatic Injury of the Spinal Cord
Hyperbaric Oxygenation (HBO) in Traumatic Spinal Cord Injury. (EOS) - Pilot Study
Hypothesis of the Study: Based on the presented results, the investigator hypothesises that HBO preserves neurons that are not irreversibly damaged (i.e. severed) during initial trauma, thus enabling regain of their function.
- Trial name
- NCT03101982
- Testing
- HBO
- Where
- Austria
- Volunteers
- 11 people
- Sponsor
- Medical University of Graz
Vitiligo Vulgaris
Mitochondrial Network Modulation Approach Using Hyperbaric Oxygen (HBO) Therapy and Nb-UVB for Treating Vitiligo
Vitiligo affects approximately 1 to 2% of the global population and significantly impacts people's quality of life. Achieving the best treatment outcomes for vitiligo involves addressing the autoimmune inflammatory response for…
- Trial name
- MitOxyVit (NCT07557693)
- Testing
- OXYGENE MEDICINAL LIQUIDE AIR PRODUCTS MEDICAL
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Late Effect of Radiation
Hyperbaric Oxygen - a New Treatment Modality in Patients With Radiation Damaged Salivary Gland Tissue
Randomized clinical trial regarding the effect of hyperbaric oxygen on late radiation tissue injury to salivary gland tissue.
- Trial name
- NCT01606644
- Testing
- Hyperbaric oxygen
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Lone Forner
Hyperbaric Oxygen Therapy, Recovery Time
Hyperbaric Oxygen Therapy in Distal Radius Fractures: Can it Shorten Recovery Time and Increase Fracture Healing?
This project is meant to show wether the HBOT can fasten the recovery process after surgical treatment of distal Radius fractures.
- Conditions
- Hyperbaric Oxygen Therapy, Recovery Time, Contrast Media, Sonography
- Trial name
- HBOTRadius (NCT01365780)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Breast Cancers
Hyperbaric Oxygen Therapy for Peripheral Neuropathy Due to Paclitaxel Analogs
The goal of this study was to explore the safety and efficacy of hyperbaric oxygen in the treatment of peripheral neuropathy due to paclitaxel analogues
- Trial name
- NCT06819501
- Testing
- hyperbaric oxygenation treatment, routine care
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Guangdong Provincial People's Hospital