Clinical trials: Hyperbaric Oxygen
Fracture Related Infection, Hyperbaric Oxygenation
Hyperbaric Oxygen Therapy as Adjunctive Treatment for Fracture-Related Infection
A fracture-related infection (FRI) is a difficult to treat condition in which a bone fracture and surrounding tissues are infected.
- Trial name
- SOLDIER (NCT07535164)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Osteoradionecrosis
Hyperbaric Oxygen Treatment of Mandibular Osteoradionecrosis. A Randomized Clinical Study
There is currently not sufficient evidence that hyperbaric oxygen (HBO) benefits the surgical removal of necrotic bone in osteoradionecrosis patients.
- Trial name
- NCT00760682
- Testing
- Hyperbaric oxygen
- Where
- 4 sites in Denmark, Sweden and 1 more
- Volunteers
- 114 people
- Sponsor
- Lone Forner
Osteonecrosis of the Femoral Head
Triple-Modal Therapy in Early-Stage Femoral Head Osteonecrosis (TM-ONFH)
This retrospective observational study evaluates the clinical and radiological outcomes of patients with early-stage osteonecrosis of the femoral head treated with a combination of core decompression, stromal vascular fraction…
- Trial name
- TM-ONFH (NCT07560163)
- Testing
- Core decompression, stromal vascular fraction (SVF), Hyperbaric Oxygen Therapy (HBOT)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Fibrosis
Treatment of Radiation-induced Fibrosis in the Upper Aerodigestive Tract Cancer by a Combination of Pentoxifylline-tocopherol and Hyperbaric Oxygen
The pentoxifylline used with tocopherol achieves a certain effectiveness in the treatment of the fibrosis. Hyperbaric oxygen therapy has been recommended and used in a wide variety of medical conditions including the treatment of…
- Trial name
- ORT-OXI-2009 (NCT01822405)
- Testing
- pentoxifylline with tocopherol, pentoxifylline+tocopherol + Hyperbaric Oxygen Therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitario de Canarias
Brain Injury, Sequelae
Hyperbaric Oxygen Therapy in Chronic Stable Brain Injury
The purpose of this study is to discover the feasibility of conducting clinical research in individuals with chronic sequelae following brain injury who are given hyperbaric oxygen.
- Conditions
- Brain Injury, Sequelae, Stroke, Anoxia
- Trial name
- HYBOBI (NCT00830453)
- Testing
- Hyperbaric oxygen therapy (HBO2)
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Intermountain Health Care, Inc.
Breast Cancer, Lung Metastasis
Concept-verification Clinical Trial on the Inhibition of Breast Cancer Lung Metastasis Progression by Hyperbaric Oxygen
This is a proof-of-concept clinical trial focused on exploring whether hyperbaric oxygen therapy (HBOT) can inhibit the progression of lung metastasis in breast cancer patients.
- Conditions
- Breast Cancer, Lung Metastasis, Hyperbaric Oxygen Therapy
- Trial name
- HBOIBCLM (NCT07514728)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Jinan Central Hospital
Autistic Disorder
A Clinical Trial of the Clinical Effects of Hyperbaric Oxygen Therapy in Thai Autistic Children
Autism is a developmental and behavioral pattern which includes the triad of impairments, 1. social interaction 2. social communication 3. imagination.
- Trial name
- VPH (NCT00670891)
- Testing
- oxygen (Hyperbaric Oxygen Therapy)
- Where
- Thailand
- Volunteers
- 7 people
- Sponsor
- Vachira Phuket Hospital
Covid19
Hyperbaric Oxygen as an Adjuvant Treatment for Patients With Covid-19 Severe Hypoxemia
The severity of COVID-19 is related to the level of hypoxemia, respiratory failure, how long it lasts and how refractory it is at increasing concentrations of inspired oxygen.
- Trial name
- NCT04477954
- Testing
- Hyperbaric Oxygen
- Where
- 3 sites in Argentina
- Volunteers
- 40 people
- Sponsor
- Asociación Argentina de Medicina Hiperbárica e Investigación
Traumatic Brain Injury
The Effects of Hyperbaric Oxygen on Non-acute Traumatic Brain Injury
Traumatic brain injury (TBI) continues to be a major cause of death and disability throughout the world. The reduced cerebral blood flow secondary to the direct trauma-induced damage deregulates cerebral metabolism and depletes…
- Trial name
- NCT05387018
- Where
- China
- Volunteers
- 390 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Neurologic Deficiency, Traumatic Brain Injury
The Effect of Hyperbaric Oxygen Therapy on Patients Suffering From Neurologic Deficiency Due Traumatic Brain Injury
Traumatic brain injuries (TBI) are a major cause of morbidity and mortality worldwide. Due to improvements in emergency medical care, transportation and specialized trauma facilities, the number of people surviving TBI with…
- Trial name
- NCT00715052
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center
Acute Ischemic Stroke From Large Vessel Occlusion
HBO After Thrombectomy for AIS With LVO
The purpose of this RCT trial is to evaluate whether the sequential hyperbaric oxygen therapy can improve the 90-day functional outcome in patients with acute large vessel occlusion ischemic stroke after endovascular treatment.
- Trial name
- NCT07626450
- Testing
- Hyperbaric oxygen therapy plus standard medical treatment, Standard medical treatment
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Beijing Tiantan Hospital
Covid19, Neurocognitive Dysfunction
Hyperbaric Oxygen Therapy for Post-COVID-19 Syndrome
Post-COVID-19 syndrome is an assembly of symptoms, following an infection with Coronavirus disease 2019 (COVID-19). The syndrome is characterized by cognitive impairment, fatigue, sleep disorders, smell and taste disorders, pain…
- Trial name
- HBOTpCOVID (NCT04647656)
- Testing
- Hyperbaric oxygen
- Where
- Israel
- Volunteers
- 91 people
- Sponsor
- Assaf-Harofeh Medical Center
Stroke
HBOT Global Functioning After Stroke
Stroke is one of the leading causes of disability and death in North America and Europe. Up to 30% of stroke survivors never recuperate completely and suffer from loss of function and poor quality of life.
- Trial name
- NCT02666469
- Testing
- Hyperbaric Oxygen Therapy (HBOT) and Exercise Program, Exercise Program, Hyperbaric Multiplace Chamber
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University Health Network, Toronto
Stroke, Ischemic Stroke
Hyperbaric Oxygen Post Established Stroke
The purpose of this study is to examine the role of Hyperbaric Oxygen Therapy (HBOT) in improving neurological function in patients who are 6 to 36 months post ischemic stroke.
- Conditions
- Stroke, Ischemic Stroke, Established Stroke
- Trial name
- HOPES (NCT02582502)
- Testing
- Hyperbaric Oxygen
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- University of British Columbia
Hyperbaric Oxygen Therapy, Stroke
The Effectiveness of Hyperbaric Oxygen Therapy on Pneumonia Complicating Stroke
To investigate the evidence for the integration of hyperbaric oxygen therapy (HBOT) as part of interdisciplinary stroke rehabilitation.
- Conditions
- Hyperbaric Oxygen Therapy, Stroke, Pneumonia
- Trial name
- NCT04376359
- Testing
- hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Ya Zhang
Insulin Resistance Syndrome
Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopause
Background: In postmenopausal females, Insulin resistance is commonly encountered in clinical setting. Hyperbaric oxygen therapy have been proposed effective in lowering blood glucose level and improving function.
- Trial name
- NCT06806345
- Testing
- Hyperbaric oxygen therapy, Hypoglycemic Drug
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Barotrauma;Ear
Pseudoephedrine Prophylaxis for Prevention of Middle Ear Barotrauma in Hyperbaric Oxygen Therapy
Hyperbaric oxygen therapy (HBOT) utilizes 100% oxygen delivery at a pressure greater than 1 atm for the treatment of various emergent medical conditions including carbon monoxide poisoning.
- Trial name
- NCT04332211
- Testing
- Hyperbaric Oxygen Therapy, Pseudoephedrine 60 MG
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Maryland, Baltimore
Cerebral Small Vessel Diseases
Effect of Hyperbaric Oxygen on Functional Connectivity in Patients With Cerebral Small Vessel Disease
Patients will have a Functional MRI before and after 10 hyperbaric Oxygen treatments.
- Trial name
- NCT02890888
- Testing
- hyperbaric oxygen treatment
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- St. Luke's Hospital, Chesterfield, Missouri
Necrotizing Fascitis
Hyperbaric Oxygen Treatment for Necrotizing Fasciitis and Necrotizing Soft Tissue Infections
The goal of this clinical trial is to learn if hyperbaric oxygen is beneficial in treating necrotizing infections and decreasing rates of morbidity and mortality. This study therefore has two aims: 1.
- Trial name
- NCT07170020
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Corewell Health West
Bell Palsy
Effect of Adjuvant Hyperbaric Oxygen Therapy on Bells Palsy Outcome
This is a randomized, single blinded, non-placebo controlled that will compare one group of Bells Palsy patients receiving the current standard of care including oral corticosteroids and oral antivirals against an experimental…
- Trial name
- NCT03457025
- Testing
- Oral Corticosteroids, Oral antivirals, Hyperbaric Oxygen Therapy
- Where
- United States
- Sponsor
- NYU Langone Health