Clinical trials: Hyperbaric Oxygenation
Osteoradionecrosis, Osteoradionecrosis of Jaw
Combination Therapy: Hyperbaric Oxygen and PENTOCLO for Treatment of Osteoradionecrosis of the Mandible
Radiation is commonly used to treat cancer in the head and neck, however, this can lead to a serious complication called osteoradionecrosis (ORN), where there is necrotic (dead) open bone inside or outside of the mouth.
- Conditions
- Osteoradionecrosis, Osteoradionecrosis of Jaw, Osteoradionecrosis of the Mandible
- Trial name
- NCT06055257
- Testing
- modified PENTOCLO (mPENTOCLO)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
Vaso-occlusive Crisis, Sickle Cell Anemia Crisis
Hyperbaric Oxygen Therapy in Sickle Cell Pain
Sickle cell anemia is a genetic blood disorder where red blood cells are abnormally shaped, crescent- or sickle-shaped, instead of the normal, round shape.
- Trial name
- HAVOC (NCT03412045)
- Testing
- hyperbaric oxygen therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Nebraska
Diabetic Foot Ulcer
Effectiveness of Diabetic Recovery Shoes and Artificial Intelligence Supported Structured Exercise Program
This study aims to evaluate the effectiveness of the diabetic recovery sandal and artificial intelligence supported structured exercise program in individuals diagnosed with diabetic foot receiving hyperbaric oxygen therapy.
- Trial name
- NCT06515665
- Testing
- therapeutic foot orthosis
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hacettepe University
Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy
Treatment of U.S. Veterans With Mild Traumatic Brain Injury With Hyperbaric Oxygen Therapy
Mild traumatic brain (mTBI) injury affects 400,000 U.S. Veterans resulting in physical, cognitive and mental health symptoms. The Department of Defense (DoD) reported 26 suicides a day from mTBI despite ongoing care for the…
- Conditions
- Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy, Depression
- Trial name
- NCT06665633
- Testing
- Oxygen 100 % Gas for Inhalation, Hyperbaric Oxygen Therapy Chamber
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nova Southeastern University
Breast Cancers
Hyperbaric Oxygen Therapy for Peripheral Neuropathy Due to Paclitaxel Analogs
The goal of this study was to explore the safety and efficacy of hyperbaric oxygen in the treatment of peripheral neuropathy due to paclitaxel analogues
- Trial name
- NCT06819501
- Testing
- hyperbaric oxygenation treatment, routine care
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Guangdong Provincial People's Hospital
Diabetic Peripheral Neuropathic Pain (DPN)
Hyperbaric Oxygen Therapy Versus High Power Laser for Diabetic Neuropathy
The purpose of this study is to compare the clinical effects of Hyperbaric Oxygen Therapy (HBOT) versus High-Intensity Laser Therapy (HPLT) on sensorimotor functions and nerve conduction in patients suffering from painful…
- Trial name
- HBOT-HPLT-DPN (NCT07848867)
- Testing
- Conventional Physiotherapy Program, Hyperbaric Oxygen Therapy, High-Intensity Laser Therapy
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Aging
A Dosing Study of Hyperbaric Oxygen Therapy (HBOT) on Epigenetic Aging
This study aims to assess the impact of hyperbaric oxygen therapy on a number of outcomes, including epigenetic aging, inflammation, and cellular health.
- Trial name
- HBOT (NCT05297019)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TruDiagnostic
Otitic Barotrauma
Inner and Middle Ear Effects of Hyperbaric Oxygen Thrapy
Audiological evaluation performed to patients on hyperbaric oxygen therapy to see its effects on middle ear pressure
- Trial name
- NCT04186741
- Testing
- Hyperbaric oxygen
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Covid19
Hyperbaric Oxygen for Long COVID-19 Pulmonary Sequela
This is a pilot study in 24 subjects where half will be randomized to 10 treatments with hyperbaric oxygen (HBO). It will primarily study pulmonary sequelae with imaging and physiological measurements (low dose chest computer…
- Trial name
- NCT04905888
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Sponsor
- Peter Lindholm
Cardiovascular Fitness, Inflammation
Evaluating Whether Hyperbaric Oxygen Therapy Can Improve VO₂-Max and Reduce Inflammation Markers in Healthy Adults Ages 30-60.
The purpose of this study is to determine whether hyperbaric oxygen therapy (HBOT) at 1.75 atmospheres of pressure (ATA) improves cardiovascular fitness (VO₂ max) and reduces inflammation in healthy adults.
- Trial name
- NCT07361861
- Testing
- Hyperbaric Oxygen Therapy
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Chronic Neurological Deficiency, Stroke
Hyperbaric Oxygen Therapy Induced Neuroplasticity in Post Stroke Patients Suffering Chronic Neurological Deficiencies
The aim of the current work was to evaluate, for the first time in a prospective randomized study, the effect of HBOT on patients with chronic neurological deficiency due to stroke.
- Trial name
- NCT00715897
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- 2 sites in Israel
- Volunteers
- 74 people
- Sponsor
- Assaf-Harofeh Medical Center
Post Low Grade Glioma Surgery, Cognitive Deficits
Hyperbaric Oxygen Therapy Can Improve Cognitive Deficits Post Low Grade Glioma Removal Surgery
The aim of the current study is to evaluate, in a prospective cross-over, randomized study, the effect of hyperbaric oxygen therapy (HBOT) on patients with chronic impairment after low grade glioma tumor removal surgery
- Trial name
- NCT02122042
- Testing
- HBOT
- Where
- Israel
- Volunteers
- 62 people
- Sponsor
- Assaf-Harofeh Medical Center
Hyperbaric Oxygenation, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Initiation Time in Acute Carbon Monoxide Poisoning
Hyperbaric oxygen therapy (HBO2) is recommended for symptomatic patients within 24 h of carbon monoxide (CO) poisoning. However, previous major studies found significantly better outcomes with HBO2 in patients treated within 6 h.
- Conditions
- Hyperbaric Oxygenation, Carbon Monoxide Poisoning, Time
- Trial name
- NCT04656912
- Testing
- Hyperbaric oxygen therapy
- Where
- South Korea
- Volunteers
- 706 people
- Sponsor
- Wonju Severance Christian Hospital
Wounds and Injuries
Tissue Perfusion and Blood Flow Monitoring Technology
The purpose of this study is to investigate the safety and efficacy of an optical device designed and developed to quantitatively monitor blood flow velocity of wound sites.
- Trial name
- WoundImager (NCT01139567)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- CW Optics, Inc.
Avascular Necrosis of Femur Head
Investigation of the Effect of Hyperbaric Oxygen Therapy in Patients With Avascular Necrosis
Avascular necrosis is a condition that occurs when bone tissue loses sufficient blood flow. This condition causes bone cells to die and, as a result, bone structure to deteriorate.
- Trial name
- NCT07142018
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Carbon Monoxide Poisoning
One vs. Three Hyperbaric Oxygen Treatments for Acute Carbon Monoxide Poisoning
This randomized trial will investigate important clinical outcomes of patients with acute carbon monoxide poisoning randomized to receive either one or three hyperbaric oxygen treatments.
- Trial name
- 1V3CORCT (NCT00465855)
- Testing
- Hyperbaric Oxygen (HBO2) - 3 sessions, Hyperbaric Oxygen (HBO2) - 1 session
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Intermountain Health Care, Inc.
Acute Kidney Injury
Hyperbaric Oxygen Therapy and Acute Kidney Injury
Kidney injury is a serious complication of cardiac surgery that occurs in up to 30% of patients and increases the risk of adverse outcomes.
- Trial name
- NCT02743754
- Testing
- Standard therapy, Hyperbaric Oxygen
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- University Health Network, Toronto
Post Stroke Depression
Hyperbaric Oxygen Therapy for Persistent Post Stroke Depression
The study evaluates the effect of HBOT on depression in patients suffering from persistent symptoms of post stroke depression (PSD) in an double blind sham control study.
- Trial name
- NCT07423273
- Testing
- hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 142 people
- Sponsor
- Assaf-Harofeh Medical Center
Cerebral Decompression Illness, All Phases
Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Cerebral Decompression Illness
Chart review of patients who received hyperbaric oxygen therapy for cerebral decompression illness who also underwent SPECT brain blood flow imaging to see if SPECT brain imaging tracks and is consistent with the clinical…
- Trial name
- NCT02105194
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Paul G. Harch, M.D.
Traumatic Injury of the Spinal Cord
Hyperbaric Oxygenation (HBO) in Traumatic Spinal Cord Injury. (EOS) - Pilot Study
Hypothesis of the Study: Based on the presented results, the investigator hypothesises that HBO preserves neurons that are not irreversibly damaged (i.e. severed) during initial trauma, thus enabling regain of their function.
- Trial name
- NCT03101982
- Testing
- HBO
- Where
- Austria
- Volunteers
- 11 people
- Sponsor
- Medical University of Graz