Clinical trials: Hyperbaric Oxygenation
Fibromyalgia, Chronic Pain
HBOT in Fibromyalgia
Fibromyalgia (FM) is a chronic pain condition affecting several millions of Canadians. Although the etiology and pathophysiology are poorly understood, there is a well-recognized association between muscular pain in fibromyalgia…
- Trial name
- NCT02467218
- Testing
- Hyperbaric Oxygen Treatment
- Where
- 2 sites in Canada
- Volunteers
- 16 people
- Sponsor
- University Health Network, Toronto
Optic Neuropathy, Glaucoma
Hyperbaric Oxygen Therapy for Optic Neuropathies
The purpose of the study is to evaluate the neuroprotective efficacy of hyperbaric oxygen for the treatment in patients with optic neuropathy.
- Trial name
- HBOT (NCT06128720)
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Heart Arrest, Brain Injuries
A Comprehensive Evaluation of Hyperbaric Oxygen Therapy in Resuscitation Medicine - a Pilot Study (HOT-RESUS 1 Trial)
In this prospective pilot study, the effects of hyperbaric oxygen therapy (HBOT) in post-cardiac arrest syndrome will be evaluated. However, the primary outcome of this pilot study will be the feasibility of this approach.
- Trial name
- HOT-RESUS 1 (NCT05646875)
- Testing
- hyperbaric oxygen therapy
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Osteoradionecrosis
The Effect of Hyperbaric Oxygen Treatment in Patients With Osteoradionecrosis.
Osteoradionecrosis (ORN) is a severe delayed radiation-induced injury that can occur in patients whom have been subjected to radiotherapy for head and neck cancer. Hyperbaric oxygen treatment (HBO) is one treatment option.
- Trial name
- ORN (NCT04934644)
- Testing
- Hyperbaric oxygen treatment
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Göteborg University
Carbon Monoxide Poisoning, Neurologic Sequelae
Adjunct Targeted Temperature Management in Acute Severe Carbon Monoxide Poisoning
This randomized trial will investigate important neurocognitive clinical outcomes of patients with acute severe carbon monoxide poisoning (ASCOP) randomized to receive either therapeutic hypothermia or normothermia combined with…
- Conditions
- Carbon Monoxide Poisoning, Neurologic Sequelae, Hypothermia
- Trial name
- NCT04975867
- Testing
- Targeted therapeutic hypothermia, Targeted therapeutic normothermia
- Where
- 2 sites in South Korea
- Volunteers
- 37 people
- Sponsor
- Wonju Severance Christian Hospital
Necrotizing Soft Tissue Infection, Necrotizing Fascitis
Prognosis and Treatment of Necrotizing Soft Tissue Infections: A Prospective Cohort Study
The investigators will analyze biomarkers related to the prognosis and treatment of necrotizing soft tissue infections (NSTI). The focus will be on whether certain endothelial and immune system biomarkers can function as markers…
- Conditions
- Necrotizing Soft Tissue Infection, Necrotizing Fascitis, Gas Gangrene, Fournier Gangrene
- Trial name
- ProTreat (NCT03147352)
- Testing
- Hyperbaric oxygen therapy
- Where
- Denmark
- Volunteers
- 260 people
- Sponsor
- Ole Hyldegaard
Disorders of Consciousness, Vegetative State
AI-Assisted Precision Hyperbaric Oxygen Therapy Based on Dynamic BIS-EEG Feedback for Patients With Disorders of Consciousness
Disorders of consciousness (DoC) are severe neurological conditions characterized by impaired awareness and reduced interaction with the environment.
- Conditions
- Disorders of Consciousness, Vegetative State, Minimally Conscious State
- Trial name
- AI-HBOT-DoC (NCT07855848)
- Testing
- AI-Assisted Personalized Hyperbaric Oxygen Therapy, Conventional Hyperbaric Oxygen Therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Autistic Disorder
A Clinical Trial of the Clinical Effects of Hyperbaric Oxygen Therapy in Thai Autistic Children
Autism is a developmental and behavioral pattern which includes the triad of impairments, 1. social interaction 2. social communication 3. imagination.
- Trial name
- VPH (NCT00670891)
- Testing
- oxygen (Hyperbaric Oxygen Therapy)
- Where
- Thailand
- Volunteers
- 7 people
- Sponsor
- Vachira Phuket Hospital
Hyperbaric Oxygen Therapy, Diabetic Foot Ulcer
Short Duration Hyperbaric Oxygen Therapy to Improve HbA1c, Leukocyte, and Serum Creatinine
The investigators want to evaluate the short duration HBOT can improve glycohemoglobin (HbA1c) levels, leukocyte count, and serum creatinine levels in patients with DFU (diabetic foot ulcer) Wagner 3-4.
- Conditions
- Hyperbaric Oxygen Therapy, Diabetic Foot Ulcer, Type II Diabetes Mellitus
- Trial name
- NCT03615755
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Volunteers
- 30 people
- Sponsor
- Hendry Irawan
Autism
A Controlled Trial of the Clinical Effects of Hyperbaric Therapy in Autistic Children
Autism is a neurodevelopmental disorder currently affecting as many as 1 out of 166 children in the United States. Autism is considered by many to be a permanent condition with little hope for improvement.
- Trial name
- NCT00335790
- Testing
- Hyperbaric Therapy
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- International Hyperbarics Association
Inflammatory Bowel Disease (IBD), Crohn Disease
Hyperbaric Oxygen Therapy for Perianal Fistulizing Crohn's Disease Not Responsive or Intolerant to Conventional Care: HYPNOTIC Pilot Study
This study aims to test a new treatment called hyperbaric oxygen therapy (HBOT) for a severe type of inflammatory bowel disease called perianal Crohn's disease (PCD).
- Trial name
- HYPNOTIC (NCT06109961)
- Testing
- Oxygen Gas for Inhalation, Standard of care
- Volunteers
- 54 people
- Sponsor
- University of British Columbia
Endometriosis-related Pain
The HEROES Trial: Hyperbaric Oxygen Therapy for Endometriosis-Related Pain
Endometriosis, is a condition where tissue from the uterus, called endometrium, grows outside of the uterus. This effects up to 10% of women, and can lead to long-lasting, moderate to severe pelvic pain, infertility and other…
- Trial name
- HEROES (NCT06579040)
- Testing
- Monoplace Hyperbaric Chamber (Class III medical device)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Sunnybrook Health Sciences Centre
Healthy, Athletes
The Effect of Hyperbaric Oxygen Therapy on Aerobic and Anaerobic Physical Fitness
Previous evidence showed hyperbaric oxygen can enhance aerobic and anaerobic performance during the exposure. The effect of continuous exposure of hyperbaric oxygen on performance was never evaluated.
- Trial name
- SPORTRCT (NCT03524989)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Israel
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Radiation Pneumonitis
Hyperbaric Oxygen in the Prevention of Radiation Pneumonitis
Radiotherapy is one of the important treatments to improve the survival rate of breast cancer patients, but also has the risk of radiation lung injury, which can develop into pulmonary fibrosis.
- Trial name
- NCT05189496
- Testing
- hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Guangdong Provincial People's Hospital
Erectile Dysfunction, Hyperbaric Oxygen Therapy
HBOT Application in Erectile Dysfunction
Recent studies have shown that hyperbaric oxygen therapy (HBOT) can induce angiogenesis and improve impaired organ function. HBOT was also recently suggested as a possible therapy for ED due to surgical injuries.
- Trial name
- HBOTED (NCT02619383)
- Testing
- Hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 37 people
- Sponsor
- Assaf-Harofeh Medical Center