Clinical trials: Hyperbaric Oxygenation
Chronic Interstitial Cystitis, Painful Bladder Syndrome
Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder
Pilot study to determine feasibility for treating patients with two chronic inflammatory conditions of the urinary bladder: chronic interstitial cystitis and recurrent urinary tract infections using a standardized hyperbaric…
- Conditions
- Chronic Interstitial Cystitis, Painful Bladder Syndrome, Recurrent Urinary Tract Infection
- Trial name
- HBOTCICrUTI (NCT03143920)
- Testing
- Hyperbaric Oxygen Therapy-
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, San Diego
Obesity, Type 2 Diabetes
Hyperbaric Oxygen Therapy and Insulin Resistance (HOTAIR2) - Effect of One HBO Session.
Obesity is an epidemic in Western society and is the biggest risk factor for insulin resistance and type 2 diabetes. The investigators have recently shown that exposure to hyperbaric oxygen (HBO) leads to an increase insulin…
- Trial name
- HOTAIR2 (NCT02009813)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Australia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Adult and Pediatric Chronic Cerebral Disorders
Oxygen Toxicity of HBOT in Chronic Brain Injury
Hypothesis: That HBOT can be toxic in the low-pressure range.
- Trial name
- NCT00592891
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Paul G. Harch, M.D.
Hyperbaric Oxygenation, Cardiorespiratory Fitness
Retrospective Analysis of CPET and Cognitive Tests of Healthy Individuals, Treated With 60 Treatment of HBOT
This retrospective observational study evaluates physiological and cognitive changes following a series of 60 hyperbaric oxygen therapy (HBOT) sessions in healthy individuals.
- Conditions
- Hyperbaric Oxygenation, Cardiorespiratory Fitness, Cognition
- Trial name
- HBOT (NCT07596641)
- Testing
- Hyperbaric Oxygen Therapy - HBOT
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Hyperbaric Oxygen Therapy, Traumatic Brain Injury
Hyperbaric Oxygen Therapy Effect on Post Concussion Syndrome in Children
Due its high incidence, mTBI and its consequences of PPCS are a major public health issue. There is no consensus regarding the treatment of PPCS in pediatrics.
- Conditions
- Hyperbaric Oxygen Therapy, Traumatic Brain Injury, Post-Concussion Syndrome
- Trial name
- TBIPED (NCT03339037)
- Testing
- Hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 52 people
- Sponsor
- Assaf-Harofeh Medical Center
Combinational Immunotherapy, Hepatocellular Carcinoma Non-Resectable
Hyperbaric Oxygen Therapy Combined Camrelizumab in Patients With Advanced/Metastatic Hepatocellular Carcinoma
The purpose of this study is to explore the efficacy and safety of hyperbaric oxygen therapy plus Camrelizumab as a second-line treatment in patients with advanced hepatocellular carcinoma who have failed at least 1 previous…
- Conditions
- Combinational Immunotherapy, Hepatocellular Carcinoma Non-Resectable, Hyperbaric Oxygen Therapy
- Trial name
- CCGLC-003 (NCT05031949)
- Testing
- hyperbaric oxygen therapy plus Camrelizumab
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhang Bi Xiang, MD
Radiation-induced Xerostomia
Hyperbaric Oxygen for the Treatment of a Dry Mouth Which Occurred After Radiotherapy
The purpose of this study is to determine whether hyperbaric oxygen is effective in the treatment of a dry mouth that occured after radiotherapy for head and neck tumours.
- Trial name
- NCT00682747
- Testing
- Hyperbaric oxygen
- Where
- 2 sites in Germany
- Volunteers
- 13 people
- Sponsor
- Thomas Kuhnt
Ptsd
Hyperbaric Oxygen Therapy for Adult Onset Post Traumatic Stress Disorder
Posttraumatic stress disorder (PTSD) is the long term effect of severely distressing traumatic event characterized by intrusive thoughts, nightmares, and avoidance.
- Trial name
- NCT03466554
- Testing
- Hyperbaric oxygen-90 minutes exposure to 100% oxygen at 2 ATA, with 5-minute air breaks every 20 minutes
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia
Use of Hyperbaric Oxygen Therapy to Improve Umbilical Cord Blood Stem Cell Homing and Subsequent Engraftment
By doing this study, researchers hope to learn the following: If providing hyperbaric oxygen (HBO) therapy prior to an umbilical cord blood (UBC) transplant will help to improve the homing process The safety of HBO administration…
- Conditions
- Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome (MDS), Hodgkins Lymphoma
- Trial name
- NCT02099266
- Testing
- Administration of hyperbaric oxygen
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Kansas Medical Center
Suicide
Self-hangIng Patient and Hyperbaric Oxygen Therapy _ SIPHON Study
During an attempted hanging, patients present severe neurological distress that can lead to major neuropsychiatric sequelae. These sequelae are notably due to significant cerebral edema related to hanging.
- Trial name
- SIPHON (NCT07461272)
- Testing
- OXYGENE MEDICINAL LIQUIDE AIR PRODUCTS MEDICAL
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille
Barotrauma
Barotrauma in Hyperbaric Oxygen Therapy
The purpose of this research is to study whether the use of pseudoephedrine can help prevent middle ear trauma during HBOT. Pseudoephedrine is an approved drug that is used for temporary relief of nasal or sinus pain and pressure.
- Trial name
- HBOT (NCT05697328)
- Testing
- Pseudoephedrine Pill
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- John Muir Health
Diabetes Mellitus, Claudication, Intermittent
Additional Hyperbaric Oxygen After Lower Extremity Amputation
This study evaluates the effect of additional hyperbaric oxygen therapy after lower extremity amputation. The patients will be randomized after amputation to either a treatment group receiving hyperbaric oxygen therapy, or…
- Conditions
- Diabetes Mellitus, Claudication, Intermittent, Critical Limb Ischemia, Osteomyelitis
- Trial name
- AHOLEA (NCT03594344)
- Testing
- Hyperbaric oxygen therapy
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
COVID-19
Compassionate Use of Hyperbaric Oxygen Therapy
This is an observational patient registry of COVID-19 patients treated with HBOT.
- Trial name
- NCT04386265
- Where
- 11 sites in United States, Poland
- Volunteers
- 100 people
- Sponsor
- SerenaGroup, Inc.
Hamstring Injury
Hyperbaric Oxygen Therapy in HAMstring Injury (HOTHAM) Trial
The goal of this study is to learn if Hyperbaric Oxygen Therapy is able to accelerate and improve muscle healing following an acute hamstring injury. The main questions it aims to answer are: 1.
- Trial name
- HOTHAM (NCT06526728)
- Testing
- Hyperbaric oxygen
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- JL Tol
Brain Injuries, Traumatic, Neuropsychology
The Role of Hyperbaric Oxygen and Neuropsychological Therapy in Cognitive Function Following Traumatic Brain Injury
Traumatic brain injury (TBI) caused by accidents is a very important public health problem in Taiwan. There are many people with brain damage and cognitive dysfunction caused by traumatic brain injury every year.
- Trial name
- NCT03900182
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hung-Chen Wang
Myeloma
Repeated HBO Therapy in Myeloma Patients Undergoing High-Dose Therapy and Auto-HCT
Subjects with multiple myeloma (MM) who are considered eligible for high-dose therapy and autologous stem cell transplantation by the transplant team at WCI will be enrolled in the study.
- Trial name
- NCT04862676
- Testing
- Hyperbaric oxygen
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Rochester
Crohn's Disease, Perianal Fistulas
The Influence of Hyperbaric Oxygen in Patients With Perianal Crohn's Disease Already Treated With TNF Alpha Blockers Treated With TNF Alpha Blockers
The aim of this study is to evaluate the effect of hyperbaric oxygen therapy (HBOT) on patient suffering from residual Crohn's disease related perianal fistulas already treated with TNF alpha blockers
- Trial name
- NCT01828190
- Testing
- Hyperbaric oxygen
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Chronic Renal Failure
Hyperbaric Oxygen Therapy for Renal Regeneration in Diabetic Nephropathy
Diabetes kidney disease is a leading cause for end stage renal disease in the western world. To date no treatment that can reverse renal damage exists.
- Trial name
- NCT03376282
- Testing
- Hyperbaric Oxygen oxygen therapy (HBOT)
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Assaf-Harofeh Medical Center
Stem Cell Transplant Complications
Hyperbaric Oxygen Therapy for Hemorrhagic Cystitis Post HSCT
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative therapy for many malignant or nonmalignant hematological diseases.
- Trial name
- NCT04502628
- Testing
- Hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shandong Provincial Hospital
Diabetes Mellitus
Hyperbaric Oxygenation in Diabetic Ulcer
Hyperbaric oxygenation (HBO) involves breathing of 100% oxygen under elevated ambient pressure. In correlation to the pressure level oxygen dissolves in the plasma resulting in an increase of total oxygen in the body.
- Trial name
- NCT02042339
- Testing
- Hyperbaric oxygen
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Medical University of Graz