Clinical trials: Hyperbaric Oxygenation
Post-Concussion Syndrome, Traumatic Brain Injury
Hyperbaric Oxygen Treatment to Treat Mild Traumatic Brain Injury (mTBI)/Persistent Post-Concussion Syndrome (PPCS)
Objective/Hypothesis: An eight-week course of forty low-pressure Hyperbaric Oxygen Treatment's (HBOT's) can significantly improve symptoms and cognitive function in subjects with the persistent-post concussion syndrome (PPCS) of…
- Trial name
- NCT02089594
- Testing
- Hyperbaric Oxygen, No Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Traumatic Brain Injury, Post-Concussion Syndrome
Cognitive Effects of Hyperbaric Oxygen Therapy (HBOT) After a Traumatic Brain Injury
This is a retrospective, single-center observational study evaluating the cognitive effects of hyperbaric oxygen therapy (HBOT) in adults who sustained a traumatic brain injury (TBI).
- Trial name
- NCT07883668
- Testing
- Hyperbaric Oxygen Therapy - HBOT
- Volunteers
- 1,000 people
- Sponsor
- Assaf-Harofeh Medical Center
Pouchitis, Hyperbaric Oxygen Therapy
Hyperbaric Oxygen Therapy for Antibiotic Refractory Pouchitis
The aim of current study is to evaluate the effect of hyperbaric oxygen therapy for the treatment of chronic antibiotic-refractory pouchitis.
- Trial name
- HBOT-pouch (NCT03526796)
- Testing
- Hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Jinling Hospital, China
Glioblastoma
Adebrelimab Plus Temozolomide ± Hyperbaric Oxygen for Primary Glioblastoma
This is a prospective, randomized, open-label, multicenter phase II study. Newly-diagnosed primary glioblastoma patients who have undergone maximal safe resection or biopsy and completed standard concurrent chemoradiotherapy will…
- Trial name
- NCT07789379
- Testing
- Adebrelimab, Temozolomide, Procedure:Hyperbaric Oxygen Therapy
- Volunteers
- 94 people
- Sponsor
- Wei Jiang
Diabetes, Foot Ulcer
Hyperbaric Oxygen Therapy as Adjunctive Treatment of Chronic Diabetic Foot Ulcers
The purpose of this study is to evaluate if hyperbaric oxygen therapy heels more foot ulcers as compared to placebo in patients with diabetes mellitus and chronic foot ulcers.
- Conditions
- Diabetes, Foot Ulcer, Healing
- Trial name
- HODFU (NCT00953186)
- Testing
- hyperbaric air, HBOT
- Where
- Sweden
- Volunteers
- 94 people
- Sponsor
- Mrs. Thelma Zoegas Foundation
Post-COVID-19 Syndrome, Post-COVID Syndrome
Treatment of Post-COVID-19 With Hyperbaric Oxygen Therapy: a Randomized, Controlled Trial
The goal of this clinical try is to investigate the effect of hyperbaric oxygen therapy (HBOT) on symptoms, quality of life and absence of work through sickness in patients with post-COVID on short- and mid-term, as well as to…
- Conditions
- Post-COVID-19 Syndrome, Post-COVID Syndrome, Post COVID-19 Condition, Post-COVID Condition
- Trial name
- NCT06267300
- Testing
- Hyperbaric oxygen
- Where
- 7 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Erasmus Medical Center
Fibromyalgia, Interstitial Cystitis
HBOT for Patients With IC/FM (Interstitial Cystitis/Fibromyalgia)
The investigators observed 12 fibromyalgia and interstitial cystitis patients undergoing hyperbaric oxygen oxygen treatment in a multiplace pressure chamber for 90 minutes, 40 treatment each, using an oro-nasal mask.
- Trial name
- IC/FMHBOT (NCT03693001)
- Testing
- Intermittent Exposure to Oxygen via Oro-Nasal Mask
- Volunteers
- 12 people
- Sponsor
- University of South Florida
Acute Acoustic Trauma
Efficacy of Various Treatments for Acute Acoustic Trauma.
Acute acoustic trauma is a growing concern in the IDF. there is currently no accepted treatment. The present retrospective study is intended to evaluate the efficacy of different treatment modalities in the IDF between 01/01/2010…
- Trial name
- NCT04482998
- Testing
- No intervention - retrospective study
- Where
- Israel
- Volunteers
- 250 people
- Sponsor
- Medical Corps, Israel Defense Force
Barotrauma;Ear, Tympanum; Perforation
Effectiveness of Sequential Eustachian Tube Maneuvers in Hyperbaric Oxygen Conditions
Middle ear barotrauma represents the predominant complication associated with hyperbaric oxygen therapy, manifesting symptoms ranging from otalgia to tympanic membrane perforation.
- Trial name
- NCT06408363
- Testing
- Maneuver group
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Felicio Rocho
Alcohol Withdrawal Symptoms, Delirium Tremens (DTs)
Hyperbaric Oxygenation in Treatment of Alcohol Dependence Syndrome
A 30 alcohol dependent patients were divided into A: Treatment group and B: Placebo group using simple randomization technique. (Liver function tests) GGT, ALT and AST levels and MCV (Mean corpuscular volume) at admission and 2…
- Trial name
- NCT03470168
- Testing
- Hyperbaric Oxygenation Therapy, Normobaric Oxygenation therapy
- Volunteers
- 30 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Breast Cancer, Radiation Toxicity
The Effect of Hyperbaric OxygeN Therapy on brEast Cancer Patients With Late Radiation toxicitY - UMBRELLA HONEY Trial
The "Hyperbaric OxygeN therapy on brEast cancer patients with late radiation toxicity" (HONEY) trial aims to evaluate the effectiveness of HBOT on late radiation toxicity in breast cancer patients using the trial within cohorts…
- Trial name
- HONEY (NCT04193722)
- Testing
- Hyperbaric oxygen therapy
- Where
- Netherlands
- Volunteers
- 189 people
- Sponsor
- UMC Utrecht
Disorder Related to Lung Transplantation, Central Airway Stenosis
Hyperbaric Oxygen Therapy for Lung Transplantation
The objective of this study is to evaluate the effect of hyperbaric oxygen therapy (HBOT) on airway complications in post-lung transplant recipients with evidence of restricted levels of blood and oxygen in the airway tissue.
- Conditions
- Disorder Related to Lung Transplantation, Central Airway Stenosis, Airway Exudative Plaques, Airway Complications Post-Lung Transplantation
- Trial name
- NCT02363959
- Testing
- Hyperbaric Oxygen Therapy, Endobronchial Biopsy of Airway Epithelium
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University
FASD
Hyperbaric Oxygen Therapy Compared to Cognitive Training in FASD
Fetal Alcohol Spectrum Disorder (FASD) describes a wide range of adverse physical, behavioral and cognitive effects resulting from prenatal alcohol exposure (PAE) during embryonic and fetal development.
- Trial name
- NCT04664790
- Testing
- Hyperbaric Oxygen, Cognitive training
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
Traumatic Brain Injury
Hyperbaric Treatment of Traumatic Brain Injury (TBI)
This study is designed to test the hypothesis that patients with Traumatic Brain Injury (TBI)treated with Hyperbaric (HBO) will show improvement in function and an increased blood flow as evidenced by single-photon emission…
- Trial name
- TBI (NCT01847755)
- Testing
- Oxygen at 1.5 ATA (atmospheres absolute).
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Barry Miskin, MD
Metabolic Dysfunction-associated Steatotic Liver Disease, Hepatic Steatosis
Hyperbaric Oxygen Therapy for Metabolic Dysfunction-associated Steatotic Liver Diseases
The goal of this clinical trial is to learn if hyperbaric oxygen therapy (HBOT) works to treat Metabolic Dysfunction-associated Steatotic Liver Diseases (MASLD).
- Conditions
- Metabolic Dysfunction-associated Steatotic Liver Disease, Hepatic Steatosis, Non-alcoholic Fatty Liver Diseases
- Trial name
- MASLD (NCT06619808)
- Testing
- Hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Jinling Hospital, China
Osteonecrosis of the Femoral Head
Triple-Modal Therapy in Early-Stage Femoral Head Osteonecrosis (TM-ONFH)
This retrospective observational study evaluates the clinical and radiological outcomes of patients with early-stage osteonecrosis of the femoral head treated with a combination of core decompression, stromal vascular fraction…
- Trial name
- TM-ONFH (NCT07560163)
- Testing
- Core decompression, stromal vascular fraction (SVF), Hyperbaric Oxygen Therapy (HBOT)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Periampullary Tumor, Common Bile Duct Neoplasms
Pancreaticoduodenectomy With or Without Preoperative Hyperbaric Oxygen Therapy
The primary objective of this study is to assess the safety, tolerability and toxicity of preoperative HBOT in patients undergoing a pancreaticoduodenal resection for premalignant and malignant tumors of the common bile duct…
- Conditions
- Periampullary Tumor, Common Bile Duct Neoplasms, Duodenal Neoplasms
- Trial name
- HBOT (NCT02575014)
- Testing
- Preoperative hyperbaric oxygen
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Florida Hospital Tampa Bay Division
TBI (Traumatic Brain Injury)
Long Lasting Effect of Hyperbaric Oxygen Therapy on Cognitive Function in Traumatic Brain Injury Patients
To evaluate the cognitive functions of patients who suffered brain injury due to traumatic head injury and were previously treated in a hyperbaric chamber between one and four years after the end of treatment.
- Trial name
- NCT07430150
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Radiation Injury, Radiation-Induced Complications
Hyperbaric Oxygen Therapy for Treatment of Severe Radiation-Induced Complications
This study evaluates the safety and effectiveness of hyperbaric oxygen therapy (HBOT) for the treatment of severe radiation-induced complications in patients previously treated with radiotherapy.
- Conditions
- Radiation Injury, Radiation-Induced Complications, Radiation Necrosis
- Trial name
- NCT07422168
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- Slovenia
- Volunteers
- 39 people
- Sponsor
- Institute of Oncology Ljubljana
Wound, Biofilm
Clinical Implications of Biofilm in Chronic Wound
Chronic wounds are important economic and health-care problem. Biofilm has been recognized as a major factor in wound chronicity, delayed healing, and persistent infections, increasing the need for frequent dressing changes…
- Conditions
- Wound, Biofilm, Chronic Pain, Quality of Life
- Trial name
- NCT05054244
- Testing
- standard wound treatment, Hyperbaric oxygenation (HBOT)
- Where
- Croatia
- Volunteers
- 140 people
- Sponsor
- University of Rijeka