Clinical trials: Hyperbaric Oxygenation
Microcirculation, Wound Healing
Hyperbaric Oxygen Therapy in Calcaneal Intraarticular Fractures: Can it Decrease the Soft-tissue Complication Rate?
This study aims to test the hypothesis that postoperative daily hyperbaric oxygen therapy (HBOT) decreases soft-tissue complication rate during the operative handling of intra-articular calcaneal fractures. Minor motivations: 1.
- Trial name
- HOCIF (NCT01264146)
- Testing
- HBOT
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Intracranial Meningioma, Neurologic Deficits
Hyperbaric Oxygen Therapy Can Improve Neurological State Post Meningioma Removal Surgery
The aim of the current study is to evaluate, in a prospective cross-over, randomized study, the effect of hyperbaric oxygen therapy (HBOT) on patients with chronic neurological deficits and cognitive impairment after anterior…
- Trial name
- NCT02084927
- Testing
- HBOT
- Where
- Israel
- Volunteers
- 62 people
- Sponsor
- Assaf-Harofeh Medical Center
Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy for Comatose Patients With Acute Carbon Monoxide Poisoning
Carbon monoxide poisoning still places a burden on the healthcare system worldwide. While oxygen therapy is the cornerstone treatment, the role and practical modalities of hyperbaric oxygen therapy (HBO) remain controversial.
- Trial name
- NCT01099995
- Testing
- Hyperbaric oxygen therapy
- Where
- France
- Volunteers
- 170 people
- Sponsor
- University of Versailles
Cerebral Stroke
Hyperbaric Oxygen Therapy After Stroke - PILOT
The goal of this pilot study is to establish more information about hyperbaric oxygen therapy for this group of patients, and give us more information of how to initiate the best possible main study.
- Trial name
- NCT04149379
- Testing
- Hyperbaric oxygen
- Where
- Norway
- Sponsor
- Norwegian Underwater Intervention (NUI)
Neuropsychiatric Sequelae of Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Carbon Monoxide Poisoning
That SPECT brain imaging tracks and is consistent with clinical history and physical exam as well as cognitive testing.
- Trial name
- NCT00596180
- Testing
- HBOT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Paul G. Harch, M.D.
Secondary Lymphedema
Hyperbaric Oxygen Therapy to Reduce Lymphedema After Breast Cancer -an Explorative Clinical Trial
The purpose of this study is to examine if pressurechamber treatment (HBOT) can reduce early stages of breast cancer related lymphedema, and to explore the mechanisms involved in the disease progress.
- Trial name
- HBOT-LYCA (NCT02895724)
- Testing
- Medical Oxygen
- Volunteers
- 20 people
- Sponsor
- Danish Cancer Society
COVID-19
Hyperbaric Oxygen Therapy (HBOT) as a Treatment for COVID-19 (COVID-19) Infection
Patients who meet inclusion criteria will be randomized into treatment vs control group. Treatment groups will undergo Hyperbaric Oxygen Therapy (HBOT) and compared to the control group.
- Trial name
- NCT04343183
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Sponsor
- Ochsner Health System
Fracture Related Infection, Hyperbaric Oxygenation
Hyperbaric Oxygen Therapy as Adjunctive Treatment for Fracture-Related Infection
A fracture-related infection (FRI) is a difficult to treat condition in which a bone fracture and surrounding tissues are infected.
- Trial name
- SOLDIER (NCT07535164)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Colitis, Ulcerative
Hyperbaric Oxygen Therapy for Ulcerative Colitis Flares
Ulcerative colitis (UC) is a chronic inflammatory bowel disease associated with recurrent mucosal inflammation. Clinically, the disease is characterized by bloody diarrhea, abdominal pain, and constitutional symptoms such as…
- Trial name
- HBO-UC (NCT03494764)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- 8 sites in United States
- Volunteers
- 39 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Gastric (Stomach) Cancer
XELOX Combined With Sintilimab and HBO for Advanced or Metastatic GC/GEJC
This study investigates the efficacy and safety of XELOX chemotherapy combined with sintilimab and hyperbaric oxygen therapy (HBOT) as a first-line treatment for patients with Advanced or Metastatic gastric and gastroesophageal…
- Trial name
- NCT06742411
- Testing
- XELOX+Sintilimab+HBOT
- Where
- 2 sites in China
- Volunteers
- 57 people
- Sponsor
- West China Hospital
Brain Injury, Chronic
Treatment of Traumatic Brain Injury With Hyperbaric Oxygen Therapy
The purpose of this study is to determine if hyperbaric oxygen therapy (HBOT) improves the cognitive function of OIF/OEF individuals who have chronic mild to moderate traumatic brain injury (TBI).
- Trial name
- NCT00810615
- Testing
- Hyperbaric oxygen @ 2.4 ATA
- Volunteers
- 50 people
- Sponsor
- San Antonio Military Medical Center
Autism, Oxidative Stress
Effect of Hyperbaric Therapy on Markers of Oxidative Stress in Children With Autism
This study will look at the changes taking place in the blood levels of key markers of oxidative stress. Oxidative stress is the biological equivalent of rust on a car. It changes vital cell chemistry.
- Trial name
- NCT00263367
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The International Child Development Resource Center
Post-circumsion Complications
Management of Post-circumcision Ischemia Using Hyperbaric Oxygen Therapy
Background: Post-circumcision penile ischaemia is a rare but destructive complication. Our goal is to present our experience in the management of children, who had different forms of penile ischaemia, complicating the routine…
- Trial name
- NCT05152511
- Testing
- Hyperbaric oxygen therapy
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Aswan University Hospital
Middle Ear Barotrauma
Effects of Hyperbaric Oxygen Therapy on Middle and Inner Ear Functions
The goal of this observational study is to measure the effect of hyperbaric oxygen therapy on middle ear pressure in order to predict the risk factors for middle ear barotrauma also, to assess its effects on hearing functions of…
- Trial name
- HBOT (NCT06209021)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetes, Periodontitis
Hyperbaric Oxygen Therapy as Adjunctive Therapy to Scaling and Root-planing in the Management of Periodontitis in Patients With Type 2 Diabetes
Diabetes and Periodontitis are both prevalent diseases affecting millions of Americans. Periodontitis is prevalent among Diabetics.
- Trial name
- NCT02671136
- Testing
- Hyperbaric Oxygen therapy, Conventional Wound Therapies
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Loma Linda University
Chronic Heart Failure With Reduced Ejection Fraction
A Prospective, Single-center, Randomized Controlled Clinical Study Evaluating the Efficacy and Safety of Hyperbaric Oxygen Therapy as an Adjunctive Treatment for Chronic Heart Failure
This study aims to investigate whether adjunctive hyperbaric oxygen therapy, compared to guideline-directed medical therapy with the "New Four Pillars" (ARNI/ACEI/ARB + β-blocker + MRA + SGLT2 inhibitor) alone, improves cardiac…
- Trial name
- NCT07311109
- Testing
- hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Fujian Medical University
Autism, Oxidative Stress
Effects of Hyperbaric Oxygen Therapy in Autistic Children: A Pilot Study
Autism is a neurodevelopmental disorder that currently affects as many as 1 out of 166 children in the United States. Autism is considered by many to be a permanent condition with little hope for improvement.
- Conditions
- Autism, Oxidative Stress, Inflammation
- Trial name
- NCT00324909
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- International Hyperbarics Association
Crush Injury
Use of Hyperbaric Oxygen Therapy for the Treatment of Crush Injuries
The purpose of this study is to determine whether using hyperbaric oxygen (HBO) improves wound healing for patients who have a crush injury.
- Trial name
- NCT04049721
- Testing
- HBO, Standard of Care
- Where
- United States
- Sponsor
- NYU Langone Health
Retinitis Pigmentosa
Slowing the Degenerative Process, Long Lasting Effect of Hyperbaric Oxygen Therapy in Retinitis Pigmentosa
Our aim was to assess the role and usefulness of Hyperbaric oxygen therapy in a long lasting period, assessing its efficacy on rescuing retinal photoreceptors and preserving visual function in retinitis pigmentosa.
- Trial name
- NCT00461435
- Testing
- hyperbaric oxygen therapy
- Where
- Italy
- Sponsor
- Azienda Policlinico Umberto I
Hyperbaric Oxygenation, Oxygen Toxicity
Selected Lysosomal Enzyme Activities and the Oxidant-antioxidant Balance in Hyperbaric Oxygen Condition.
The aim of the research project was to investigate the effects of hyperbaric oxygen (HBO) treatment on the redox equilibrium in individuals with different pathological conditions.
- Conditions
- Hyperbaric Oxygenation, Oxygen Toxicity, Antioxidants, Oxidative Stress
- Trial name
- NCT06401941
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Nicolaus Copernicus University