Clinical trials: Hyperbaric Oxygenation
Post Traumatic Stress Disorder
Hyperbaric Oxygen Therapy for Post Traumatic Stress Disorder
The study evaluates the effect of hyperbaric oxygen therapy on veterans with combat-associated PTSD in an double blind sham control study.
- Trial name
- HBOT (NCT04518007)
- Testing
- hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 56 people
- Sponsor
- Assaf-Harofeh Medical Center
Long COVID, Post Acute Sequelae of COVID-19
Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine Trial - Effect of Hyperbaric Oxygen Therapy for the Treatment of Post COVID Condition
The RECLAIM study platform will be used to explore whether the use of Hyperbaric Oxygen therapy (HBOT) improves the symptoms of post covid cognitive dysfunction. Hyperbaric oxygen therapy is a well-established medical treatment.
- Conditions
- Long COVID, Post Acute Sequelae of COVID-19, Post-COVID-19 Condition
- Trial name
- RECLAIM-HBOT (NCT06452095)
- Testing
- Hyperbaric Oxygen therapy
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Brain and Central Nervous System Tumors, Cognitive/Functional Effects
Hyperbaric Oxygen Therapy in Treating Patients With Radiation Necrosis of the Brain
RATIONALE: Hyperbaric oxygen may increase blood flow and decrease swelling in areas of the brain damaged by radiation therapy. Giving hyperbaric oxygen therapy together with dexamethasone may be an effective treatment for…
- Conditions
- Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Radiation Toxicity
- Trial name
- NCT00087815
- Testing
- dexamethasone, hyperbaric oxygen, cognitive assessment
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Barrett Cancer Center
Sarcoma, Hyperbaric Oxygen Therapy
Hyperbaric Oxygen Therapy for Soft Tissue Sarcoma Pilot Study
A parallel-group randomized pilot trial at a single institution (Duke University) on the effect of postoperative hyperbaric oxygen therapy on wound healing in patients with soft tissue sarcoma undergoing surgical resection with…
- Trial name
- NCT03144206
- Testing
- Hyperbaric oxygen
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University
Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder
HBOT Effects on First Responders' Cognition and Well-Being
The goal of this study is to examine changes in cognitive functioning and post-concussive symptoms following hyperbaric oxygen therapy (HBOT) in current and former first responders with a history of traumatic brain injury.
- Conditions
- Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT07852728
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Summit Hyperbarics and Wellness
Brain Injury, Chronic
Hyperbaric Oxygen for Traumatic and Non-traumatic Brain Injury
The purpose of this study is to examine whether 40 hyperbaric oxygen sessions has effect on long-term symptoms after brain injury.
- Trial name
- HYBOBI2 (NCT01986205)
- Testing
- Hyperbaric Oxygen, Minimal pressure air
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Lindell Weaver
Aging
Angiogenesis Induced in the Elderly by Hyperbaric Oxygen Therapy
Recent studies show preliminary evidence of HBOT therapeutic effects on angiogenesis, increased tissue blood flow and oxygenation correlated with tissue function.
- Trial name
- ANGIOHBOT (NCT02790541)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Ulcer Foot, Diabetic Foot Ulcer
Adjunctive Hyperbaric Oxygen Therapy (HBOT) for Lower Extermity Diabetic Ulcer:
Diabetic foot ulcers are associated with high risk of amputation. About 50% of patients undergoing non-traumatic lower limb amputations are diabetics5.
- Trial name
- NCT03675269
- Testing
- HBOT, Standard wound care
- Sponsor
- King Hamad University Hospital, Bahrain
Hyperbaric Oxygen Therapy, Carbon Monoxide Poisoning
Optimal Number of Hyperbaric Oxygen Treatments for Carbon Monoxide Poisoning
The optimal treatment strategy with hyperbaric oxygen therapy has been the subject of some debate over the past 3 decades. Initial landmark studies showed a decrease in the incidence of DNS with a single treatment and also with…
- Trial name
- NCT06619717
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Alberta
Hyperbaric Oxygen Therapy, Stroke
The Effectiveness of Hyperbaric Oxygen Therapy on Pneumonia Complicating Stroke
To investigate the evidence for the integration of hyperbaric oxygen therapy (HBOT) as part of interdisciplinary stroke rehabilitation.
- Conditions
- Hyperbaric Oxygen Therapy, Stroke, Pneumonia
- Trial name
- NCT04376359
- Testing
- hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Ya Zhang
Post-concussive Symptoms, Traumatic Brain Injury
Hyperbaric Oxygen Therapy (HBO2) for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (mTBI)
This is a Phase II randomized trial designed to describe the magnitude of change between baseline and follow-up outcomes for symptom surveys and a battery of neuropsychological tests administered at time points corresponding…
- Trial name
- HOPPS (NCT01306968)
- Testing
- hyperbaric oxygen
- Where
- 5 sites in United States
- Volunteers
- 79 people
- Sponsor
- U.S. Army Medical Research and Development Command
Anxiety
The Effect of Emotional Freedom Technique and Virtual Reality Glasses on Anxiety and Vital Signs
The aim of the study was to examine the effects of the emotional freedom technique and virtual reality glasses applied to individuals receiving hyperbaric oxygen therapy for the first time on anxiety and vital signs.
- Trial name
- NCT06384274
- Testing
- Emotional Freedom Technique, Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Trigeminal Neuralgia, Pain
Clinical Trial of Hyperbaric Oxygen Treatment in Trigeminal Neuralgia Patients
The purpose of this study is to determine whether the hyperbaric oxygen treatment reduces pain and improve the life quality in trigeminal neuralgia patients.
- Trial name
- NCT00866424
- Testing
- Hyperbaric oxygen, Mock hyperbaric chamber
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xijing Hospital
Type 2 Diabetes Mellitus
Bone Marrow Mononuclear Cell and Hyperbaric Oxygen Therapy in Diabetes Mellitus
There were evidences that the non-immune mediated inflammatory pathways of cell damage occurred in vitro in human islets upon hyperglycemia in type 2 diabetes mellitus.
- Trial name
- NCT00767260
- Testing
- BM-MNC+HOT, BM-MNC, HOT
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Fuzhou General Hospital
Changes in Peripheral Blood Population Numbers and Type.
Stem Cell Quantification In Peripheral Blood After Hyperbaric Oxygen Therapy Treatments
This is an observational research study whose purposes are to see the effects of repeated hyperbaric oxygen therapy treatments on the levels of stem/progenitor cells in peripheral circulating blood following five days of…
- Trial name
- NCT01740908
- Testing
- Hyperbaric Oxygen Treatment
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Restorix Research Institute, LLLP
Necrotizing Soft Tissue Infection
Adjunctive Hyperbaric Oxygen Treatment for Patients With Necrotizing Soft-Tissue Infection (HOT-NSTI Trial).
Necrotizing soft-tissue infection (NSTI) is a rare, severe, fast-progressing bacterial infection within the soft tissue compartment. The NSTI mortality rate remain high and largely unaltered in the last decades.
- Trial name
- HOT-NSTI (NCT07489274)
- Testing
- Hyperbaric oxygen treatment, Standard of Care (Investigator Choice)
- Where
- 2 sites in Belgium, Norway
- Volunteers
- 1,480 people
- Sponsor
- Ole Hyldegaard
Oligospermia
Hyperbaric Oxygen Therapy for Men Suffering From Infertility Due to Oligospermia.
Infertility in a couple is defined as the inability to achieve conception despite one year of frequent, unprotected intercourse. Infertility affects approximately 12% of couples attempting to conceive.
- Trial name
- NCT05842239
- Testing
- Hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Erectile Dysfunction
New Treatment in Erectile Dysfunction Patients.
Erectile dysfunction patients who are non responder to sildenafil will be treated with hyperbaric oxygen therapy with 100% concentration and at 2 ATM for 30 consecutive sessions each one 90 minutes and then will be reassessed.
- Trial name
- NCT05439486
- Testing
- hyperbaric oxygen therapy within hyperbaric oxygen therapy chamber.
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Healthy Active Athletes
Intermittent Hypoxic Training (IHT) Versus Hyperbaric Oxygen Therapy (HBOT) for Aerobic Performance
Comparing the effect of HBOT and IHT on aerobic performance of athletes.
- Trial name
- NCT05447416
- Testing
- Hyperbaric Oxygen Therapy - HBOT, Intermittent Hypoxic Training - IHT
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Post COVID-19 Condition, Post-COVID-19 Syndrome
Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments
Over 500 million people have been infected with COVID-19, and to date, more than 6 million people have died. Many individuals who have recovered from COVID-19 continue to experience symptoms even after they have been "cured" of…
- Conditions
- Post COVID-19 Condition, Post-COVID-19 Syndrome, Post-COVID Syndrome, COVID-19
- Trial name
- PCS-HBOT (NCT06082518)
- Testing
- Monoplace Hyperbaric Chamber (Class III medical device).
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Sunnybrook Health Sciences Centre