Clinical trials: Hyperbaric Oxygenation
Skin Ulcer
The Regeneration Effects of Derma-PACE Shockwave in Chronic Diabetic Ulcers
Management of chronic diabetic foot skin ulcers require multidisciplinary approaches including diabetic control, wound care, antibiotic, shoe wear off-loading, and surgery in selected cases.
- Trial name
- NCT01219127
- Testing
- Derma-PACE
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Diabetes Mellitus, Type II, Insulin Resistance
Insulin Sensitivity During Hyperbaric Oxygen Compared to Hyperbaric Air
In a recent series of studies performed by our group, we have shown that exposure to hyperbaric oxygen (HBO) leads to an increase in insulin sensitivity in male subjects with type-2 diabetes (T2DM) and in obese and overweight men…
- Trial name
- HOTAIR4 (NCT03138746)
- Testing
- HBO, Hyperbaric air
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- University of Adelaide
Sickle Cell Disease, Hyperbaric Oxygen Therapy
Hyperbaric-oxygen Therapy (HBOT) Versus Placebo for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD)
This is a randomised, controlled, double-blind, placebo trial of HBOT (intervention) superiority in the treatment of VOC in SCD, to demonstrate the effectiveness of HBOT for the decrease in pain level in the treatment of SCD-VOC.
- Conditions
- Sickle Cell Disease, Hyperbaric Oxygen Therapy, Vaso-occlusive Crisis
- Trial name
- HBOT-SCD (NCT05289700)
- Testing
- HBOT in Hyperbaric chamber
- Where
- 3 sites in France, Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Osteonecrosis, Avascular Necrosis
Effect of HBOT on Femoral Head Avascular Necrosis (AVN)
The primary objective of this study is to determine whether the Hyperbaric Oxygen Therapy (HBOT) conducted under the Marx Protocol improves pain outcomes when combined with core decompression with autologous bone marrow aspirate…
- Trial name
- NCT06931301
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Yale University
Wounds and Injuries
Laser Speckle Imaging for Wound Perfusion Monitoring (WoundImager)
The purpose of this study is to investigate the efficacy of an optical device designed and developed to quantitatively monitor blood flow velocity of wound sites.
- Trial name
- NCT01675583
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- CW Optics, Inc.
Long COVID, Long COVID-19 Syndrome
Quality of Life After Hyperbaric Oxygen Therapy in Post-COVID Patients
Post-Covid syndrome, also known as long Covid, is a clinical condition in which patients experience long term symptoms after Covid-19 infection. Treatment options for post-Covid are not effective.
- Conditions
- Long COVID, Long COVID-19 Syndrome, Long Covid19, Long Covid 19
- Trial name
- QoL COVID HBOT (NCT06159309)
- Testing
- Hyperbaric oxygen therapy
- Where
- 6 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- Rutger Lalieu
Breast Reconstruction, Lipofilling
Hyperbaric Oxygen Therapy to Improve Autologous Fat Graft Intake in Irradiated Breast
The goal of this clinical trial is to learn if hyperbaric oxygen therapy (HBOT) enhances fat graft survival in lipofilling procedures in irradiated breast cancer patients.
- Conditions
- Breast Reconstruction, Lipofilling, Hyperbaric Oxygen Therapy
- Trial name
- NCT07140198
- Testing
- Hyperbaric Oxygen Therapy, Control
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- University Hospital, Geneva
Residual Neurological, Cognitive, Emotional, Behavioral Effects From Traumatic Brain Injury
Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Traumatic Brain Injury
Hypothesis: That SPECT brain imaging tracks and is consistent with clinical improvements in patients receiving hyperbaric oxygen therapy (HBOT) for chronic traumatic brain injury.
- Trial name
- NCT00594503
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Paul G. Harch, M.D.
Sudden Sensorineural Hearing Loss (SSNHL), Hyperbaric Oxygen Therapy
Effect of Hyperbaric Oxygen Therapy(HBOT) on Patients With Sudden Sensorineural Hearing Loss(SSNHL) and Coagulation Function
The objective of this observational study was to understand the effect of HBO on patients with SSNHL and its association with coagulation function and prognosis.
- Trial name
- NCT06819202
- Testing
- Hyperbaric oxygen treatment
- Where
- China
- Volunteers
- 1,309 people
- Sponsor
- Sun Yuting
Acute Thermal Burns
The Effects of Hyperbaric Oxygen Therapy (HBOT) on Acute Thermal Burns
The blinded RCTstudy aims to: Determine the effects of HBOT on burns conversion for patients who have fresh thermal burns injury using the LDI.
- Trial name
- NCT00824551
- Testing
- Hyperbaric Oxygen Therapy, Standard care
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- Singapore General Hospital
Necrotizing Fascitis, Cellulitis
Validation of the Use of the Arteriovenous Tension Difference in CO2 Under Hyperbaric Conditions
The central venous-arterial carbon dioxide tension difference is used daily in intensive care to establish peripheral tissue hypoperfusion, mainly mediated by a low cardiac index.
- Conditions
- Necrotizing Fascitis, Cellulitis, Septic Shock
- Trial name
- SEPTICO2HBO (NCT07492030)
- Testing
- Echography
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Lille
Pain, Inflammation
Hyperbaric Oxygen Therapy Attenuates Central Sensitization Induced by a Thermal Injury in Human Volunteers (HBO)
The hypothesis of this investigation is to observe if HBO have an anti-inflammatory effect in humans induced by tonic heat stimulation.
- Conditions
- Pain, Inflammation, Hyperalgesia
- Trial name
- NCT02025686
- Testing
- Hyperbaric Oxygen, Normal ambient conditions
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Per Rotbøll Nielsen
Ischemic Heart Disease
Hyperbaric Oxygen Therapy in Patients With Chronic Stable Ischemic Heart Disease: An Option for Therapeutic Angiogenesis?
Hyperbaric oxygen therapy (HBOT) is proposed as a possible in vivo angiogenic stimulator for improving microvascular myocardial perfusion and anginal symptoms as assessed by myocardial perfusion imaging and angina questionnaire…
- Trial name
- NCT02760394
- Testing
- HBOT
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Assaf Harofeh MC
Child Autism
Hyperbaric Oxygen Treatment in Autism Spectrum Disorders
Hyperbaric oxygen therapy (HBOT) is part of a multidisciplinary therapeutic management of infant autism including psychotherapy, drug treatment and other therapeutics (speech therapy, occupational therapy restrictive diet ...).
- Trial name
- NCT04472780
- Testing
- Hyperbaric oxygen Therapy HBOT
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- General Administration of Military Health, Tunisia
Chronic Fatigue Syndrome, ME/CFS
Hyperbaric Oxygen Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
This study evaluates the effects of hyperbaric oxygen therapy (HBOT) in patients with mild to moderate CFS/ME. Participants will undergo 60 HBOT sessions over 3 months with a 3-month follow-up, including physical, cognitive…
- Trial name
- HBOT-ME/CFS (NCT07621068)
- Testing
- Hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 74 people
- Sponsor
- Assaf-Harofeh Medical Center
Air or Gas Embolism, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Registry
The purpose of the Hyperbaric Oxygen Therapy Registry (HBOTR) is to provide real world patient outcome and side effect information from electronic health records submitted to a specialty specific hyperbaric registry as part of…
- Conditions
- Air or Gas Embolism, Carbon Monoxide Poisoning, Clostridial Myositis and Myonecrosis (Gas Gangrene), Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias
- Trial name
- HBOTR (NCT02483650)
- Volunteers
- 5,000 people
- Sponsor
- U.S. Wound Registry
Invasive Fungal Infections, Hyperbaric Oxygen Therapy
Hyperbaric Oxygen Therapy Used on Severely Injured Healthy Individuals With Fungal Infections
The goal of this observational study is to learn about the effects of Hyperbaric Oxygen Therapy on healthy individual who suffer from invasive fungal infection caused by severe trauma, who do not respond to conventional…
- Trial name
- NCT07120581
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Assaf-Harofeh Medical Center
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
COVID-19, Post COVID-19 Condition
Safety and Efficacy of Hyperbaric Oxygen Therapy for Long COVID Syndrome
Long COVID Syndrome (Long COVID), Post Acute COVID-19 Syndrome (PACS) or Post COVID-19 Syndrome (PCS) is defined as 'signs and symptoms that develop during or following an infection consistent with COVID-19, continue for more…
- Conditions
- COVID-19, Post COVID-19 Condition, Post COVID-19 Condition, Unspecified, Post COVID Condition
- Trial name
- HOT-LoCO (NCT04842448)
- Testing
- Hyperbaric oxygen
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska University Hospital
Radiation Injuries
Study to Determine if Hyperbaric Oxygen Therapy is Helpful for Treating Radiation Tissue Injuries
The principle objective of this research is to more precisely determine the degree of benefit that hyperbaric oxygen therapy affords in the treatment of late radiation tissue injury. The study has eight* components.
- Trial name
- NCT00134628
- Testing
- Hyperbaric Oxygen Therapy
- Where
- 7 sites in United States, Australia and 3 more
- Volunteers
- 248 people
- Sponsor
- National Baromedical Services