Clinical trials: Hypercalcemia, open to volunteers
Hypercalcemia, Renal Injury
Exploring Pathogenesis and Treatment of Hypercalcemia Caused by Intramuscular Injection of Paraffinoil
The aim of the study is to characterize paraffin oil induced granulomatous disease. We will investigate pathogenesis and natural history of paraffin disease.
- Conditions
- Hypercalcemia, Renal Injury, Paraffinoma
- Trial name
- NCT04265599
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Herlev Hospital
Idiopathic Infantile Hypercalcaemia - Severe Form, Genetic Disease
Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria
This study evaluates the efficacy of rifampin in the treatment of hypercalcemia and/or hypercalciuria in participants with at least one inactivating mutation of the CYP24A1 gene.
- Conditions
- Idiopathic Infantile Hypercalcaemia - Severe Form, Genetic Disease, Hypercalcemia, Idiopathic, of Infancy, Hypercalciuric Hypercalcemia
- Trial name
- RICHH (NCT03301038)
- Testing
- Rifampin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Philadelphia
Idiopathic Infantile Hypercalcemia - Severe Form
Vitamin D Analog in Vitamin D 24-hydroxylase Deficiency
Preclinical evaluation of a vitamin D analog for the treatment of vitamin D 24-hydroxylase using fibroblast from patients with CYP24A1 mutation.
- Trial name
- VaraD-Cell (NCT04987073)
- Testing
- skin biopsy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Comorbidities and Coexisting Conditions, Morality
Registry for Hypoparathyroidism Wuerzburg
Long-term conventional treatment of chronic hypoparathyroidism does not fully restore calcium homeostasis leading to increased morbidity, emergency events and reduced subjective health status.
- Conditions
- Comorbidities and Coexisting Conditions, Morality, Hypocalcemia, Hypercalcemia
- Trial name
- NCT05585593
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- University of Wuerzburg
Hypercalcemia, Granuloma
Hypercalcemia After Paraffin Oil Injection
Today, there is an increased use of non-medical, invasive cosmetic treatments globally without sufficient awareness of possible health risks.
- Trial name
- NCT04292288
- Testing
- Biochemical observational
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Martin Blomberg Jensen
Osteoporosis, Hypercalcemia
Evaluation of the Role of Luteinizing Hormone (LH) and Human Chorionic Gonadotropin (hCG) in Adult Patients Undergoing Assessment for Endocrine Disorders
Hormones are chemical messengers that help regulate many functions in the body. As women go through menopause, and as men age, levels of certain reproductive hormones change significantly.
- Conditions
- Osteoporosis, Hypercalcemia, Primary Hyperparathyroidism, Adrenal Gland Disease
- Trial name
- NCT07824102
- Where
- Denmark
- Volunteers
- 20,000 people
- Sponsor
- Martin Blomberg Jensen
Cardiopulmonary Failure, Myocardial Infarction (MI)
COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable
The COR-INSIGHT trial aims to evaluate the effectiveness of Peerbridge COR advanced ambulatory ECG wearables (COR 1.0 and COR 2.0) in accurately and non-invasively detecting cardiovascular and cardiopulmonary conditions using…
- Conditions
- Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure
- Trial name
- COR-INSIGHT (NCT06763549)
- Testing
- SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Paraffinoma, Granuloma, Foreign-Body
The GranStone Trial
This study will investigate whether treatment with empagliflozin or losartan can reduce the risk of kidney stone formation in patients with paraffin disease, a condition caused by the injection of paraffin oil into muscle tissue…
- Trial name
- NCT07828002
- Testing
- empagliflozin (Jardiance) 25 mg, Losartan 100 mg
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Martin Blomberg Jensen
Primary Hyperparathyroidism, Hypercalcemia
Calcitonin Pre-treatment to Improve SPECT-CT Sensitivity
Patients with biochemically confirmed primary hyperparathyroidism and non-localizing SPECT-CT exam within the past year will be included.
- Trial name
- NCT03935984
- Testing
- Calcitonin
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Joseph Sferra