Clinical trials: Hyperemesis Gravidarum
Corneal Dystrophy, Macular Dystrophy
The Efficacy of Hyperemesis Gravidarum on Macular Thickness, Corneal Thickness and Intraocular Pressure in Pregnancy
Aim Physiological changes in intraocular pressure as well as in the cornea and macula may occur during pregnancy. In the literature, there are limited data on ocular findings in hyperemesis gravidarum.
- Conditions
- Corneal Dystrophy, Macular Dystrophy, Hyperemesis Gravidarum - Severe
- Trial name
- NCT05927740
- Testing
- Optic coherence tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Batman Training and Research Hospital
Hyperemesis Gravidarum
The Effect of Guided Imagery and Diaphragmatic Breathing Exercise in Pregnant Women With Hyperemesis Gravidarum
Objective: The aim of the researchers is to determine the effects of guided imagery and diaphragmatic breathing exercise application on nausea, vomiting severity, and anxiety level in pregnant with hyperemesis gravidarum.
- Trial name
- NCT05829473
- Testing
- Breathing Exercise Group, Guided Imagery Group
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Hyperemesis Gravidarum
Use of the Modified PUQE Score on Admitted Cases of Hyperemesis Gravidarum (HG) to Guide Response to Treatment
Use of the PUQE score to judge the need for admission in cases of hyperemesis gravidarum Evaluation of the response to treatment by the PUQE score
- Trial name
- NCT04785911
- Testing
- Antiemetic Combinations
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Tasnem Abo-elouon
Hyperemesis Gravidarum
Comparison of Gabapentin and Metoclopramide for Treating Hyperemesis Gravidarum
The investigators will compare the effectiveness of gabapentin to metoclopramide for 1 week among 60 women with hyperemesis gravidarum (HG) in this randomized, double-blinded trial.
- Trial name
- NCT02163434
- Testing
- Gabapentin, Metoclopramide
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- State University of New York at Buffalo
Hyperemesis Gravidarum, Pregnancy Related
The Levels of the Orexin, Galanin and aMSH and CART in Patients With Hyperemesis Gravidarum
Hyperemesis gravidarum is a disease of unknown etiology that is frequently encountered in pregnant women and seriously impairs their quality of life.
- Trial name
- NCT05446025
- Testing
- Blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Siirt University
Hyperemesis Gravidarum, Nausea Gravidarum
Validating the Effect og Ondansetron and Mirtazapine in Treating Hyperemesis Gravidarum
The aim is to investigate the efficacy of mirtazapine and ondansetron as treatment for hyperemesis gravidarum(HG). The setup is a double-blind multicenter trial where patients suffering from HG will be randomized to treatment…
- Conditions
- Hyperemesis Gravidarum, Nausea Gravidarum, Vomiting of Pregnancy
- Trial name
- VOMIT (NCT03785691)
- Testing
- Mirtazapine, Ondansetron
- Where
- 7 sites in Denmark
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Hyperemesis Gravidarum
Acupressure in Hyperemesis Gravidarum
To examine the degree of nausea, vomiting between the acupressure and control group in women with hyperemesis gravidarum
- Trial name
- NCT05175079
- Testing
- Acupressure band, Standard treatment hospital protocol
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Hyperemesis Gravidarum, Pregnancy Related
Gallbladder Functions & Serum Cholecystokinin Levels in Women Diagnosed With Hyperemesis Gravidarum
This study evaluates the gallbladder functions and serum cholecystokinin levels in pregnant women diagnosed with hyperemesis gravidarum.
- Trial name
- NCT03950167
- Where
- Turkey (Türkiye)
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Müge Keskin
Nausea and Vomiting of Pregnancy
The Efficacy Of Diclectin® For Nausea And Vomiting Of Pregnancy
The purpose of this study is to determine whether Diclectin® (doxylamine succinate USP 10 mg and pyridoxine HCl 10 mg) is more effective at controlling the nausea and vomiting of pregnancy than a placebo.
- Trial name
- NCT00614445
- Testing
- doxylamine succinate 10 mg/pyridoxine hydrochloride 10 mg
- Where
- 7 sites in United States
- Volunteers
- 280 people
- Sponsor
- Duchesnay Inc.
Hyperemesis Gravidarum
Hyperemesis Gravidarum and Osteoporosis
Hyperemesis Gravidarum (HG) is a common disorder for hospitalization in the first trimester of pregnancy and related to protracted vomiting and nausea. It can be accompanied by ketonuria, dehydration and weight loss.
- Trial name
- NCT03127293
- Testing
- DEXA
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Adana Numune Training and Research Hospital
Hyperemesis; Gravidarum, With Dehydration, Gestational Diabetes
Hyperemesis Gravidarum and 75 Gram Oral Glucose Tolerance Test
Hyperemesis gravidarum (HEG) is not only nausea and vomiting of pregnancy, but it is also a clinical syndrome including endocrine and metabolic complications.
- Trial name
- NCT02963753
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Hyperemesis; Gravidarum, With Dehydration
Endothelial Dysfunction in Hyperemesis Gravidarum
The purpose of the study is to determine serum inflammatory adhesion molecules levels in hyperemesis gravidarum
- Trial name
- NCT02989337
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Hyperemesis Gravidarum, Pregnancy
Nutritional Markers in Normal and Hyperemesis Pregnancies
This study evaluate the rate of nausea and nutritional status in patients with hyperemesis gravidarum (severe nausea and vomiting in pregnancy) and healthy pregnant women using a questionnaire (PUQE-score), self-reported…
- Trial name
- PUQE-M (NCT02619188)
- Testing
- PUQE-form inclusion, Nutritional form inclusion, Blood sampling inclusion
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Hyperemesis Gravidarum
Bone Health in Hyperemesis Gravidarum
The purpose of the study is to determine whether maternal bone resorption would be seen in Hyperemesis Gravidarum and could be detected in early period using serum vitamin D levels, serum calcium (Ca) levels, serum parathormone…
- Trial name
- NCT02862496
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Hyperemesis Gravidarum, Pregnancy
Pre-emptive Treatment of Severe Nausea and Vomiting of Pregnancy
The purpose of this study is to determine whether pre-emptive use of a delayed release combination of pyridoxine hydrochloride and doxylamine succinate (Diclectin®), before eruption of symptoms of Nausea and vomiting of pregnancy…
- Trial name
- NCT00293644
- Testing
- Diclectin®
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- The Hospital for Sick Children
Hyperemesis Gravidarum
The Association of Helicobacter Pylori in the Pathogenesis of Hyperemesis Gravidarum in Pregnant Women
The purpose of this study to explore the association between Hyperemesis Gravidarum in pregnant women and Helicobacter pylori infection.
- Trial name
- AOHPIPOHGIPW (NCT02830321)
- Testing
- helicopacter pylori stool antigen test (CER TEST BIOTEC)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- rasha fawzy abd el kader
Hyperemesis Gravidarum, Temperament
Assessment of the Relationship Between Affective Temperament and the Severity of Nausea and Vomiting in Early Pregnancy
In this study, the investigators aimed to research the relationship between affective temperament with the severity of the symptoms of nausea and vomiting in early pregnancy.
- Conditions
- Hyperemesis Gravidarum, Temperament, Morning Sickness
- Trial name
- NCT02541682
- Testing
- TEMPS-A (Temperament Evaluation of Memphis, Pisa, Paris and San Diego Auto-questionnaire)
- Where
- Turkey (Türkiye)
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemalpasa Government Hospital
Hyperemesis Gravidarum
Does Thiamine Help Vomiting and Nausea in Pregnancy?
There are different treatments for nausea and vomiting in pregnancy. According to the ACOG recommendations, promethazine is the first line of parenteral treatment after oral treatment had failed.
- Trial name
- NCT00861523
- Testing
- thiamine & promethazine
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- HaEmek Medical Center, Israel
Hyperemesis Gravidarum
Pregnancy Specific Nausea Questionnaire (PUQE) Translated and Tested in Norwegian
Nausea in early pregnancy (emesis gravidarum) is very common but most often self-limiting. Hyperemesis gravidarum; where nausea and vomiting is severe and protracted is potentially dangerous for the woman and her foetus and…
- Trial name
- PUQE-N (NCT01836835)
- Testing
- Pregnancy Unique Questionnaire of Emesis (PUQE), 24 hours self-reported nutritional intake form
- Where
- 2 sites in Norway
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Pregnancy, Morning Sickness
Improving Multivitamin Supplementation to Pregnant Women
The purpose of this study is to compare the tolerability of Pregvit® to a common prenatal vitamin (Orifer® F) among pregnant women with morning sickness or those suffering from a variety of conditions.
- Conditions
- Pregnancy, Morning Sickness, Nausea, Vomiting
- Trial name
- NCT02300155
- Testing
- Pregvit®, Orifer F®
- Where
- Canada
- Volunteers
- 1,370 people
- Sponsor
- The Hospital for Sick Children