Clinical trials: Hyperglycaemia (Diabetic)
Diabetes Mellitus, Diabetes Mellitus, Type 1
The SHINE Study: Safety of Implant and Preliminary Performance of the SHINE SYSTEM in Diabetic Subjects
The objectives of SHINE study are to confirm the safety aspects of the SHINE SYSTEM. Moreover, the goal of this clinical investigation is the initial evaluation of sensor's performance by assessing sensor's ability to…
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Ketoacidosis, Diabetic
- Trial name
- NCT05597605
- Testing
- The SHINE SYSTEM
- Where
- 3 sites in Belgium, France and 1 more
- Volunteers
- 6 people
- Sponsor
- Indigo Diabetes NV
Cancer, Colon Cancer
Emergence of Chemotherapy Related Hyperglycemia in nOn-diabetic Patients
To assess chemotherapy related hyperglycemia in non-diabetic patients, the investigators will assess the incidence of hyperglycemia and analyze co-medications and risk factors.
- Conditions
- Cancer, Colon Cancer, Breast Cancer, Malignant Lymphoma
- Trial name
- ECHO (NCT03062072)
- Testing
- Chemotherapy
- Where
- 2 sites in South Korea
- Volunteers
- 300 people
- Sponsor
- National Cancer Center, Korea
Obesity, Pre-diabetes
Evaluation of Lifestyle Interventions to Treat Elevated Cardiometabolic Risk in Primary Care
The purpose of the E-LITE Study is to evaluate the feasibility and potential effectiveness of two lifestyle interventions in a community based primary care setting.
- Conditions
- Obesity, Pre-diabetes, Metabolic Syndrome
- Trial name
- E-LITE (NCT00842426)
- Testing
- Self-management program (SM), Care management program (CM)
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Palo Alto Medical Foundation
Diabetes Type 2 on Insulin, Hypoglycemia (Diabetic)
Comparing Glycemic Outcomes of Carbohydrate Counting vs. Fixed Mealtime Insulin Dosing in Hospitalized Patients With Hyperglycemia
The study compares two current practices for calculating insulin dose for admitted patients: flexible fixed mealtime dosing based on percent of meal eaten and carbohydrate counting based on amount of carbohydrates eaten.
- Conditions
- Diabetes Type 2 on Insulin, Hypoglycemia (Diabetic), Hyperglycemia Due to Type 2 Diabetes Mellitus
- Trial name
- MEND (NCT07808398)
- Testing
- Carbohydrate-counting-based prandial rapid-acting insulin dosing, Flexible fixed mealtime rapid-acting insulin dosing based on percentage of meal consumed
- Volunteers
- 500 people
- Sponsor
- Mayo Clinic
Type 2 Diabetes
Effect of Raw Versus Roasted Fenugreek Seed Powder in Reducing Blood Glucose Levels in Type 2 Diabetic Patients
Diabetes is a metabolic disorder that causes high glucose levels in the blood and leads to various complications with time such as Retinopathy, neuropathy, and nephropathy, and puts a lot of burden on the health of a person as…
- Trial name
- NCT05550870
- Testing
- Raw fenugreek seed powder, Roasted fenugreek seed powder
- Where
- Pakistan
- Volunteers
- 35 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Hyperglycemia
Association Between Blood Glucose Indicators and Heart Rate Variability in Non-diabetic Critically Ill Patients
Heart rate variability (HRV) is a simple way to check how well the body's automatic nervous system is working. It does this by looking at how the heart rate changes in the electrocardiogram.
- Trial name
- NCT07198308
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Zhongshan Hospital
Diabetic Ketoacidosis, Hyperglycemia
Continuous Glucose Monitoring Using a New Subcutaneous Insulin Protocol for Mild to Moderate Diabetic Ketoacidosis
Using a prospective, mixed methods study design, the investigators will assess the feasibility, usefulness, and care team acceptability of CGM in conjunction with FSBG during implementation of the new subQ DKA/HHS protocol at…
- Trial name
- NCT06693115
- Testing
- CGM with alerts
- Where
- United States
- Sponsor
- HealthPartners Institute
Sacro Iliac Joint Pain, Diabetes
Effect of Chromium on Blood Sugar After Sacroiliac Joint Injection
The aim of this study is to investigate whether oral chromium supplementation can decrease steroid-induced hyperglycemia in diabetic patients undergoing ultrasound-guided sacroiliac joint injections through a randomized…
- Trial name
- Cr (NCT06709313)
- Testing
- Chromium
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University
Diabetic Retinopathy, Neurodegeneration
Glycemic Control and Retinal Microvascular Changes
The goal of this prospective, observational study is to compare in the association of glycemic control and retinal microvascular changes in patients with type 2 diabetes mellitus (T2DM) without diabetic retinopathy (DR).
- Conditions
- Diabetic Retinopathy, Neurodegeneration, Blood Sugar; High
- Trial name
- NCT06150495
- Where
- South Korea
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hypoglycemia (Diabetic), Hyperglycaemia (Diabetic)
Hypoglycaemia and Cardiac Arrhythmias in Type 1 Diabetes
The investigators hypothesise that patients with type 1 diabetes have clinically relevant, but often unrecognised, episodes of arrhythmias linked to episodes of hypoglycaemia and/or clinically significant fluctuations in plasma…
- Conditions
- Hypoglycemia (Diabetic), Hyperglycaemia (Diabetic), Arrythmia, Cardiac, Type 1 Diabetes
- Trial name
- Hypo-Heart-1 (NCT04011683)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Steno Diabetes Center Copenhagen
Type I Diabetes
Type 1 Diabetic Post Prandial Glycemia Evaluation Using an Algorithm
The aim of this study is to demonstrate the efficacy of an algorithm to anticipate the post prandial glycemic profile in type I diabetic patient.
- Trial name
- EGHYA (NCT05151770)
- Testing
- Measure of glycemia levels and comparison to algorithm predictions
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- M-DT1
Pre-diabetes
A Study to Evaluate the Effects of Vildagliptin on the Insulin Response to Glucose in Subjects With Pre-diabetes
This is an exploratory study to assess whether vildagliptin, an unapproved drug, can increase insulin secretion in subjects with pre-diabetes who have a defect in the insulin response and elevated levels of fasting glucose.
- Trial name
- NCT00312130
- Testing
- Vildagliptin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Novartis
Pre Diabetic
How Fig Polyphenols Affect Blood Sugar and Insulin Levels After Eating in Adults at Risk for Diabetes
The study purpose is to understand how the body absorbs and metabolizes nutrient-like components in dried figs called polyphenols over 24 hours.
- Trial name
- FG (NCT07625046)
- Testing
- Fig, Control
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Coronary Artery Disease
Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery
The purpose of this study is to compare sitagliptin and placebo for the prevention of high blood glucose during surgery.
- Trial name
- SITACABG NonDM (NCT02443402)
- Testing
- Sitagliptin, Regular Human Insulin, Insulin glargine
- Where
- 4 sites in United States
- Volunteers
- 68 people
- Sponsor
- Emory University
Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR
New Taipei City 888 Digital Medical AI Platform for Prevention and Care of the Three Highs and Cardio-Renal-Vascular Diseases
Non-communicable diseases (NCDs), or chronic diseases, are a major public health burden globally and in Taiwan, and control of the "three highs" (hypertension, dyslipidemia, and hyperglycemia) is a national priority.
- Conditions
- Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR, Cardiovascular Disease Risk Factor, Cardiovascular Disease Prevention
- Trial name
- DIGICARE-DREAM (NCT07588256)
- Testing
- Interactive digital modules, Antihypertensive Medication Management
- Where
- Taiwan
- Volunteers
- 4,162 people
- Sponsor
- New Taipei City Medical Association
Diabetes, Diabetes Mellitus
Glycemic Control in Diabetic Hospitalized Patients
With the advanced management of diabetes and new innovative anti-hyperglycemic therapy hyperglycemia remains a culprit factor affecting the outcome of patients admitted to the hospital in general wards.
- Trial name
- NCT04800861
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- AlFayhaa General Hospital
Postprandial Hyperglycemia, Type 2 Diabetes
Development of Anti-Diabetic Nutraceuticals From Legume Seed Coats
This open-label clinical trial aims to evaluate whether daily consumption of soup prepared from boiled water extracts of selected legume seed coats, seasoned with salt and spices, improves glycemic regulation in individuals with…
- Conditions
- Postprandial Hyperglycemia, Type 2 Diabetes, Metabolic Syndromes
- Trial name
- NCT07688694
- Testing
- Legumes seed soup
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- JSS MEDICAL COLLEGE, JSS ACADEMY OF HIGHER EDUCATION AND RESEARCH
Diabetes Mellitus
Characteristics of Non Diabetic Hyperglycemic Inpatients
Retrospective nested non-matched case control study comparing patients by glycemic status
- Trial name
- NCT00842010
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Cook County Health
Glucose Intolerance, Obesity
Clinical Trial to Assess the Effects of Candesartan on the Carbohydrate Metabolism of Obese Subjects
Hypothesis: The use of candesartan 16-32 mg/d for 6 months improves the carbohydrate metabolism, and decreases the plasmatic levels of adipocytokines and oxidative stress markers, in non diabetic, non hypertensive subjects with…
- Trial name
- ARAMIA (NCT00319202)
- Testing
- Candesartan
- Where
- Colombia
- Volunteers
- 56 people
- Sponsor
- Fundación Cardiovascular de Colombia
Peripheral Vascular Diseases, Hyperglycaemia (Diabetic)
Peripheral Nerve Blocks for Above-the-knee Amputations
Surgery performed with nerve blocks and sedation may be safer and provide better pain control compared to general anesthesia and opioid therapy in high-risk patient populations such as elderly and troubled with peripheral…
- Conditions
- Peripheral Vascular Diseases, Hyperglycaemia (Diabetic), Hypertension, Coronary Artery Disease
- Trial name
- NCT03404180
- Testing
- Peripheral nerve block, Intravenous Sedatives, Lateral femoral cutaneous nerve blocks
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida