Clinical trials: Hyperglycaemia (Diabetic)
Type2 Diabetes, High Blood Sugar
Evaluate Safety as Mono or Combination Therapies With Anti-diabetes Mellitus Drugs in Japanese Subjects With Type 2 Diabetes Mellitus
This is a long term, single arm, open label study to evaluate the safety and efficacy of dapagliflozin as monotherapy or in combination therapy with other anti diabetic drug in Japanese subjects with type 2 diabetes mellitus who…
- Trial name
- NCT01294436
- Testing
- Dapagliflozin
- Where
- 38 sites in Japan
- Volunteers
- 728 people
- Sponsor
- AstraZeneca
End-Stage Kidney Disease, Type 2 Diabetes Mellitus
Glucose Containing and Glucose Free Hemodialysate in Type 2 Diabetic Patients
The purpose of this study is to investigate differences in glycemia during the whole hemodialysis day and the whole freeday during hemodialysis, during the evening and the night after hemodialysis and at the same time intervals…
- Trial name
- NCT02009514
- Testing
- Glucose-containing compared to glucose-free hemodialysate
- Volunteers
- 10 people
- Sponsor
- Tampere University Hospital
Pre Diabetes
Therapeutic Intervention of Eriocitrin in the Reduction of Hyperglycemia in Pre-diabetic Individuals
Supplementation with citrus bioflavonoids (hesperidin, naringin, diosmin and eriocitrin, among others) has been associated with an improvement in the glycidic and lipid profile, reduction of insulin resistance and systemic…
- Trial name
- NCT03928249
- Testing
- Eriocitrin
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- São Paulo State University
Hyperglycemia in Pregnant Diabetic Patients, Gestatiaonl Diabetes Mellitus
Shanghai Clinical Cohort of Hyperglycemia in Pregnancy
Establish a high-quality clinical cohort of hyperglycemia in pregnancy. Develop subtype-specific, end-to-end standards for diagnosis, treatment, and follow-up across the preconception, pregnancy, and postpartum phases.
- Trial name
- SHINE (NCT07161947)
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Shanghai General Hospital, China
Diabetes Mellitus, Type 2
A Randomized, Double-Blind, Comparator- and Placebo-Controlled, Multiple-Dose Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of MSDC-0602 in Type 2 Diabetic Patients
The purpose of this study is to assess the safety and tolerability of MSDC-0602 and to evaluate the reduction in fasting plasma glucose in patients with Type 2 diabetes.
- Trial name
- NCT01280695
- Testing
- MSDC-0602 100 mg, MSDC-0602 250 mg, Pioglitazone
- Where
- 14 sites in United States
- Volunteers
- 129 people
- Sponsor
- Metabolic Solutions Development Company
Pre-diabetes
A Study to Evaluate the Effects of Vildagliptin on the Insulin Response to Glucose in Subjects With Pre-diabetes
This is an exploratory study to assess whether vildagliptin, an unapproved drug, can increase insulin secretion in subjects with pre-diabetes who have a defect in the insulin response and elevated levels of fasting glucose.
- Trial name
- NCT00312130
- Testing
- Vildagliptin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Novartis
Pre-diabetes
Supplementation of YMETA, on Gut Health, Immunity and Metabolism in Pre-diabetic Adult Population
Type 2 diabetes mellitus (T2DM) is a major non-communicable disease and one of the world's fastest growing health problems. According to a 2019 report, about 463 million adults worldwide currently have diabetes and future…
- Trial name
- YMETA (NCT05400525)
- Testing
- YMETA
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Roehampton
Type 2 Diabetes Mellitus, Pre-diabetes
Acute Effects of Cold-induced Shivering on 24-hour the Glucose Profile in Metabolically Compromised Populations
Type 2 Diabetes Mellitus (T2DM) and its associated comorbidities pose a major health concern worldwide. Although lifestyle strategies, such as exercise and diet-induced weight loss are effective interventions to counteract the…
- Trial name
- SHIVER (NCT05576025)
- Testing
- Lifestyle intervention (cold exposure)
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Diabetic Neuropathies
Role of Carnosine in Combination With Vitamin B Complex in Preventing the Progression of Diabetic Neuropathy in Type 2 Diabetes Patients
Evaluation of the influence of oral administration of carnosine in combination with vitamin B Complex in preventing the progression of diabetic neuropathy in type 2 diabetes patients.
- Trial name
- NCT05422352
- Testing
- Carnosine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Diabetes, Physical Activity
Feasibility of REHIT in NDH Patients
The aim of this feasibility study was to describe and report data relevant to the acceptability of an exercise intervention (reduced-exertion, high-intensity interval training) in non-diabetic hyperglycaemia patients delivered in…
- Trial name
- NCT04011397
- Testing
- Exercise intervention, Usual care
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Huddersfield
Type2 Diabetes
An Alternative Approach to Improve Hyperglycemia Among Type 2 Diabetes Patients
The study compared the effect of bitter melon intake and moderate exercise on postprandial glucose levels as measured by incremental area under the curve (iAUC) in eight patients with type 2 diabetes.
- Trial name
- NCT04268212
- Testing
- Bitter melon juice (100 ml), Exercise
- Volunteers
- 8 people
- Sponsor
- Arizona State University
Diabetes, Gestational, Pregnancy in Diabetics
Westlake Precision Birth Cohort
The Westlake Precision Birth Cohort (WeBirth) is a prospective cohort study among women with hyperglycemia during pregnancy and their offspring living in Hangzhou, China.
- Conditions
- Diabetes, Gestational, Pregnancy in Diabetics, Intrauterine Hyperglycemia
- Trial name
- WeBirth (NCT04060056)
- Testing
- Standardized breakfast, Standardized snack, Standardized lunch
- Where
- China
- Volunteers
- 2,001 people
- Sponsor
- Westlake University
Diabetic Foot, Resistance Exercise
Breathing-based Leg Resistance Exercise Improves Wound Healing, Blood Sugar and Quality of Life for Diabetic Foot Ulcers
The purpose of the study was designed leg resistance training combined with breathing approach, and evaluated its effect on wound healing, blood sugar control and quality of life in type 2 diabetic patients with foot ulcers.
- Conditions
- Diabetic Foot, Resistance Exercise, Wound Healing, Hyperglycemia
- Trial name
- NCT05110092
- Testing
- leg resistance combined with breathing exercise training
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Diabetes
Assessment of Response Rates and Yields for Two Tools for Early Detection of Non-diabetic Hyperglycaemia and Diabetes
The purpose of this study is to establish the most effective method of increasing attendance to screening of type 2 Diabetes within a primary care setting within the backdrop of the NHS Health Check programme.
- Trial name
- ATTEND (NCT00950313)
- Testing
- Self Assessment, Electronic risk score
- Where
- United Kingdom
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Hypoglycemia (Diabetic), Hyperglycaemia (Diabetic)
Hypoglycaemia and Cardiac Arrhythmias in Type 1 Diabetes
The investigators hypothesise that patients with type 1 diabetes have clinically relevant, but often unrecognised, episodes of arrhythmias linked to episodes of hypoglycaemia and/or clinically significant fluctuations in plasma…
- Conditions
- Hypoglycemia (Diabetic), Hyperglycaemia (Diabetic), Arrythmia, Cardiac, Type 1 Diabetes
- Trial name
- Hypo-Heart-1 (NCT04011683)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Steno Diabetes Center Copenhagen
Sacro Iliac Joint Pain, Diabetes
Effect of Chromium on Blood Sugar After Sacroiliac Joint Injection
The aim of this study is to investigate whether oral chromium supplementation can decrease steroid-induced hyperglycemia in diabetic patients undergoing ultrasound-guided sacroiliac joint injections through a randomized…
- Trial name
- Cr (NCT06709313)
- Testing
- Chromium
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University
Periodontitis, Prediabetes
Metabolic Effects of Treatment of Chronic Periodontitis in Non-diabetic Subjects
This study was aimed at assessing the effects of non-surgical periodontal treatment (NSPT) of chronic periodontitis on insulin sensitivity, glucose tolerance, and serum C-reactive protein(CRP) level amongst non-diabetic subjects.
- Trial name
- PARODIA2 (NCT02830113)
- Testing
- non-surgical periodontal treatment
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yaounde Central Hospital
Hyperglycemia, Perioperative Complication
Effect of Perioperative Glycemia Protocol on Glycemic Outcomes in Diabetic Patients Undergoing Abdominal Surgery
This study evaluated to the effects of a glycaemic control protocol directed by nurses during the perioperative period on glycaemic outcomes in diabetic patients undergoing major abdominal surgery.
- Trial name
- NCT04167410
- Testing
- glycaemic management protocol implemented to clinic
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Surgery, Non Diabetic Hyperglycemia
Prevention and Treatment of Common Hyperglycemia in Surgery Pilot
The PATCH pilot trial aims to establish feasibility and determine the sample size of a future, large-scale, multi-site RCT, as well as reinforce the long-standing known safety profile of glucose, insulin, and potassium (GIK) and…
- Trial name
- PATCHS Pilot (NCT06624956)
- Testing
- glucose, insulin, and potassium (GIK), Crystalloid Infusion
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Washington
Insulinemic Response, Type 2 Diabetes (Adult Onset)
Impact of High-Oleic Palm Oil Consumption on Cardiovascular Biomarkers in Adults in Bogotá
This randomized clinical trial aims to evaluate the effects of refined high-oleic palm oil consumption on cardiovascular risk biomarkers and insulin resistance in healthy adults.
- Conditions
- Insulinemic Response, Type 2 Diabetes (Adult Onset), Hyperglycaemia (Diabetic), Hyperlipidaemia
- Trial name
- EDCHOPA-CRB (NCT07748559)
- Testing
- High-oleic palm oil
- Where
- Colombia
- Volunteers
- 52 people
- Sponsor
- Ruby Alejandra Villamil