Clinical trials: Hyperglycemia, Postprandial
Hyperglycaemia
Effects of Polyphenols Found in Pomegranate and Olives Food Supplements on Postprandial Blood Glucose in Vivo.
Consumption of carbohydrate containing foods or sugary drinks brings about changes to the blood glucose levels. After a meal or drink, blood glucose rises until it reaches a peak concentration usually after 30 minutes.
- Trial name
- NCT02486978
- Testing
- Control (109 g white bread), Dose 1, Dose 2
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Type 2 Diabetes Mellitus, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Antidiabetic Effect of Olive Pomace Oil
This clinical trial aims at assessing whether consumption of olive pomace oil in the diet may benefit persons with type 2 diabetes mellitus or persons at risk of developing the disease (prediabetic persons).
- Conditions
- Type 2 Diabetes Mellitus, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetic State, Diabetes
- Trial name
- OPODIABE (NCT06723886)
- Testing
- Experimental arm: Olive pomace oil, High-oleic acid sunflower oil
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Postprandial Hyperglycemia
Comparison of Different Types of Resistant Starch
This study is to determine whether different types of resistant starch have different effects on blood glucose in healthy adults.
- Trial name
- NCT00930956
- Testing
- Resistant Starch
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Prediabetes
Regulation of Postprandial Nitric Oxide Bioavailability and Vascular Function By Dairy Milk
Cardiovascular disease (CVD) is the leading cause of death in the United States. Short-term increases in blood sugar, or postprandial hyperglycemia (PPH), affect blood vessel function and increase the risk of CVD.
- Trial name
- NCT02482675
- Testing
- Glucose, Glucose with Non-fat Milk, Glucose with Whey Protein Isolate
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Fasting, Postprandial Hyperglycemia
Postprandial Metabolome and Metabolic Flexibility
Metabolic flexibility is a process in which the body can switch energy substrates in different physiological states. This flexibility plays an important role in an individual's health because losing it increases the risk of…
- Conditions
- Fasting, Postprandial Hyperglycemia, Lipid Metabolism Disorders, Glucose Metabolism Disorders
- Trial name
- NCT06878781
- Testing
- High carbohydrate challenge, High lipid challenge, High proteinchallenge
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Medicina Genomica
Hyperglycemia, Postprandial
Investigation of the Glycemic Index of Ethiopian Honey
The purpose of this study is to determine which of the Ethiopian honeys slowly/rapidly raise the blood glucose level.
- Trial name
- NCT02488018
- Testing
- Provision of experimental honey
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Addis Ababa University
Type 2 Diabetes
Effects of PDE-5 Inhibition on Postprandial Hyperglycemia in Type 2 Diabetes
An increase of blood flow and capillary permeability decrease the impact of an endothelial barrier for glucose and insulin allowing them to reach their target cells in peripheral insulin sensitive organ in the human body.
- Trial name
- NCT01238224
- Testing
- Tadalafil
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Vastra Gotaland Region
Pregnancy Related, Stress, Psychological
Emotion-Diet Interactions in Pregnancy
This study will investigate how maternal emotional state following a controlled stress exposure in pregnancy influences blood glucose and insulin levels after eating a standardized meal, and whether the effects of emotional state…
- Conditions
- Pregnancy Related, Stress, Psychological, Glucose Intolerance During Pregnancy, Emotional Stress
- Trial name
- PREDIP (NCT04430439)
- Testing
- Psychosocial stress, Control non-stress
- Where
- 2 sites in United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
PreDiabetes, Impaired Glucose Tolerance
High FODMAP Diet With Metformin in preDM
This is a prospective, double blinded, randomised cross over feeding trial examine high or low FODMAP diet in combination with metformin on postprandial glucose responses and gastrointestinal tolerability and gut microbiota…
- Trial name
- NCT05628584
- Testing
- High FODMAP diet with metformin, Low FODMAP diet with metformin
- Where
- Hong Kong
- Volunteers
- 26 people
- Sponsor
- Elaine Chow
Hyperglycemia, Postprandial, Overweight and Obesity
Ketone Supplementation, Glucose Control, and Cardiovascular Function
Post-prandial hyperglycemic excursions induce a cascade of deleterious effects on the body, including increased inflammation, production of reactive oxygen species, and impaired cardiovascular function.
- Conditions
- Hyperglycemia, Postprandial, Overweight and Obesity, Diabetes Mellitus Risk
- Trial name
- NCT03817749
- Testing
- Exogenous ketone monoester
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Postprandial Hyperglycemia, Type2 Diabetes
The Attenuating Effect of Soluble Fiber Consumption on Postprandial Glycemia in Humans
The main objective of the current study is to investigate whether consumption of soluble fibers (isomaltodextrin [IMD], partially digestible maltodextrin) and RS4 starch will lower postprandial glycemia as well as postprandial…
- Conditions
- Postprandial Hyperglycemia, Type2 Diabetes, Blood Sugar; High
- Trial name
- NCT05349916
- Testing
- Control, Isomaltodextrin Low Dose, Isomaltodextrin High Dose
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Purdue University
Type 2 Diabetes
Lifestyle Control of Postprandial Hyperglycemia
Large spikes in blood glucose experienced after meals in people with type 2 diabetes are known to damage blood vessels. Low carbohydrate high fat diets and exercise can improve blood glucose control in people with type 2 diabetes…
- Trial name
- NCT02683135
- Testing
- High-carbohydrate diet, Low-carbohydrate diet, Low-carbohydrate diet with post-meal walking
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of British Columbia
Pre Diabetic
How Fig Polyphenols Affect Blood Sugar and Insulin Levels After Eating in Adults at Risk for Diabetes
The study purpose is to understand how the body absorbs and metabolizes nutrient-like components in dried figs called polyphenols over 24 hours.
- Trial name
- FG (NCT07625046)
- Testing
- Fig, Control
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Insulin Resistance
Effects of Sourdough Fermentation Duration and Acid Development on Postprandial Blood Glucose in Prediabetic Adults
The primary intervention for management of prediabetes is lifestyle changes. Eating healthier and increasing physical activity was found to slow the progression of prediabetes into diabetes, reduce the risk of other diseases like…
- Trial name
- NCT06925451
- Testing
- sourdough bread 24, sourdough bread 48, sourdough bread 72
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Arizona State University
Prediabetes, Cardiovascular Disease
Cardioprotective Activities Of Whole Eggs On Vascular Endothelial Function In Prediabetic Adults
Cardiovascular disease (CVD) is largely a lifestyle-related condition that is the #1 killer of adults in the United States. Our work is aimed at understanding how short-term increases in blood sugar, like those that accompany…
- Trial name
- NCT02364570
- Testing
- Glucose (100g), Glucose (75g), Whole Eggs
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Type 1 Diabetes
Dual-wave Boluses in Children With Type 1 Diabetes Insulin Boluses in Children With Type 1 Diabetes
To analyze with the aid of CGM the blood sugar profiles of children receiving dual-wave versus standard bolus for dinner.
- Trial name
- NCT04668612
- Testing
- Dual-bolus, Standard bolus
- Where
- Estonia
- Volunteers
- 30 people
- Sponsor
- Tartu University Hospital
Postprandial Hyperglycemia
AVACEN Treatment Method and Postprandial Blood Glucose
A double-blind crossover randomized controlled trial to investigate the effects of the AVACEN device on postprandial blood glucose. The AVACEN device creates negative pressure around the hand while heating the palm.
- Trial name
- NCT04018976
- Testing
- AVACEN 100, AVACEN 100 heat only
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Postprandial, Hyperglycemia, Postprandial
Postprandial Response to Different Jams
The aim of this study is to investigate the effects of an acute intake of three different types of strawberry jam, differing in the carbohydrates and antioxidants content, on postprandial glucose metabolism, lipid profile…
- Conditions
- Postprandial, Hyperglycemia, Postprandial, Feeding Behaviors, Antioxidant
- Trial name
- NCT01684332
- Testing
- Strawberry Jam
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Hypercholesterolemia, Postprandial Hyperglycemia
Postprandial Lipemia and Glycemia Following a High-Fat Meal
The goal of this clinical trial is to determine the acute effects on postprandial lipemia and glycemia by supplementing a high-fat meal with either white button (WB) or shiitake (SH) mushroom powder in relatively healthy adults…
- Conditions
- Hypercholesterolemia, Postprandial Hyperglycemia, Lipid Disorder
- Trial name
- NCT05619952
- Testing
- Mushroom Powder
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Sugar; Blood, High
The Acute Effect of D-allulose Consumption on Postprandial Glycaemia
The rare sugar D-Allulose, when consumed in a drink before eating has been shown to reduce the blood glucose response to high carbohydrate drinks or meals in people who are healthy, or have elevated fasting blood glucose…
- Trial name
- NCT06330636
- Testing
- D-Allulose, Sodium Saccharin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nottingham