Clinical trials: Hyperglycemia, Postprandial
Pre-diabetes
Incretins in Impaired Fasting Glucose
People with high fasting glucose can develop type 2 diabetes with the passage of time. This study is being done to determine the effect of a novel medication in people with this elevated fasting glucose.
- Trial name
- NCT00364377
- Testing
- Sitagliptin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Mayo Clinic
Postprandial Hyperglycemia
Is Mid-morning Breakfast as Healthy as Early-morning Breakfast for Blood Sugar Control in Adolescent Girls?
Repeated, elevated levels of glucose (sugar) within the blood after eating can lead to type 2 diabetes. In adults, eating breakfast lowers blood glucose responses to subsequent meals when compared with skipping breakfast.
- Trial name
- NCT05000944
- Testing
- breakfast omission (BO), early-morning breakfast consumption (EM-BC), mid-morning breakfast consumption (MM-BC)
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Hyperglycemia
Effect of a Beverage Comprised of Compounds From Olives on Post-prandial Blood Glucose Responses in Healthy Volunteers
Consumption of carbohydrate containing foods or sugary drinks brings about changes to the blood glucose levels. After a meal or drink, blood glucose rises until it reaches a peak concentration usually after 30 minutes.
- Trial name
- NCT03093753
- Testing
- Control (study 1), Test (study 1), Control (study 2)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Coronary Heart Disease, Acute Coronary Syndrome
Acarbose Cardiovascular Evaluation Trial
The purpose of this study is to determine whether acarbose therapy can reduce cardiovascular-related morbidity and mortality in patients with impaired glucose tolerance (IGT) who have established coronary heart disease (CHD) or…
- Conditions
- Coronary Heart Disease, Acute Coronary Syndrome, Impaired Glucose Tolerance, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- ACE (NCT00829660)
- Testing
- Acarbose
- Where
- 177 sites in China, Hong Kong
- Volunteers
- 6,526 people
- Sponsor
- University of Oxford
Diabetes Mellitus, Type 1, Type 1 Diabetes
Co-administration of Pramlintide and Insulin Via an Automated Dual-hormone Artificial Pancreas System in Adults With Type 1 Diabetes
One of the main challenges in maintaining tight glucose control in a closed-loop system occurs at meal times. Amylin is a gluco-regulatory beta-cell hormone that is co-secreted with insulin in response to nutrient stimuli, and is…
- Conditions
- Diabetes Mellitus, Type 1, Type 1 Diabetes, Postprandial Hyperglycemia
- Trial name
- NCT04243629
- Testing
- Rapid-Acting Insulin, Pramlintide Acetate, Artificial Pancreas
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- McGill University
Hyperglycemia, Cardiovascular Disease
Green Tea Confections For Managing Postprandial Hyperglycemia-Induced Vascular Endothelial Dysfunction
The objective of this study is to formulate and validate a green tea confection (i.e. "gummy" candy) as a strategy to attenuate postprandial hyperglycemia-induced impairments in vascular function.
- Trial name
- NCT01857258
- Testing
- Green Tea Concentrate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Blood Glucose, Postprandial, Blood Insulin, Postprandial
Effects of Berries on Post-meal Blood Sugar
The purpose of this study is to investigate whether berries are effective in lowering blood glucose and insulin responses to meals containing starch or sucrose.
- Conditions
- Blood Glucose, Postprandial, Blood Insulin, Postprandial, Hyperglycemia
- Trial name
- SOMA (NCT01580150)
- Testing
- Berries, No berries
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marjukka Kolehmainen
Postprandial Hyperglycemia
Determination of the PPG and Insulin Responses of Rice Alone and Rice Consumed With Sugardown™
This study was a partly controlled laboratory-based study comparing the short-term postprandial blood glucose and insulin responses produced by 3 test meals containing white rice alone or with SUGARDOWN™ (Galactomannan) in…
- Trial name
- NCT03375398
- Testing
- Rice, Sugardown™
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Therapeutics
Prediabetes, Hyperglycemia
Benefit of IQP-VV-102 in Reducing Postprandial Glucose Level in Overweight Caucasian Subjects
In this trial, the investigational product , the active ingredients which has been proven to reduce postprandial glucose in healthy and diabetic patients, will be tested.
- Trial name
- NCT02541344
- Testing
- Dose 1 of IQP-VV-102, Dose 2 of IQP-VV-102
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Type 2 Diabetes Mellitus
1,5-AG as a Marker of Postprandial Hyperglycemia and Glucose Variability in Well-controlled Type 2 Diabetes Mellitus
The aim of this study was to evaluate the correlation between 1,5-Anhydroglucitol in patients with HbA1C <7%, and glycemic excursions as assessed by the continuous glucose monitoring system compared to fructosamine.
- Trial name
- NCT01161797
- Where
- South Korea
- Volunteers
- 53 people
- Sponsor
- Kyunghee University Medical Center
Pre Diabetes
Impact of Whey and Leucine on Glycaemia in Adults Without Diabetes
Higher than average blood sugar (glucose) levels are linked to an increased risk of developing type 2 diabetes. As such, there is interest in identifying dietary factors that could lower blood glucose to help reduce the number of…
- Trial name
- Whey2Glo (NCT03785951)
- Testing
- Whey Protein Isolate, Wheat Protein, Wheat Protein with Leucine
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Postprandial Hyperglycemia
Glycaemic Index (GI) Evaluation of Carbohydrate-based Food with Functional Ingredients Derived from Food Sources
In Singapore, the Ministry of Health has declared a "War on Diabetes" and major efforts will be made to develop and deploy programs to prevent diabetes.
- Trial name
- NCT03989674
- Testing
- Anthocyanin
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Glucose Intolerance, Diabetes Mellitus, Type 2
Effects of Seaweed Extract on Blood Glucose Response to Sucrose
This study will examine the impact of the seaweed (Ascophyllum nodosum) extract on blood glucose levels after a sugary drink in healthy subjects.
- Conditions
- Glucose Intolerance, Diabetes Mellitus, Type 2, Healthy Diet, Postprandial Hyperglycemia
- Trial name
- NCT05461560
- Testing
- Sucrose solution, Seaweed extract in sucrose solution
- Where
- Ireland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Markers of Inflammation, Hyperglycemia, Postprandial
Effect of Hibiscus Sabdariffa Beverage
There are numerous plant foods that are a source of bioactive compounds, which can induce an anti-inflammatory effect on various pathways of inflammatory processes in the body as it may be useful in decreasing markers of…
- Conditions
- Markers of Inflammation, Hyperglycemia, Postprandial, Hyperinsulinism
- Trial name
- Hibiscus (NCT05774613)
- Testing
- Effect of a Hibiscus sabdariffa beverage
- Where
- Mexico
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Instituto Tecnológico y de Estudios Superiores de Occidente
Type2 Diabetes
Validation of Machine Learning Based Personalized Nutrition Algorithm to Reduce Postprandial Glycemic Excursions Among North American Individuals With Newly Diagnosed Type 2 Diabetes
This is an initial validation study of the Personal Nutrition Project (PNP) algorithm in a North American population with recently diagnosed Type 2 Diabetes (T2D).
- Trial name
- NCT03053518
- Testing
- Abbott Freestyle Libre Pro, LifeStyle
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Normal, Impaired Fasting Glucose
A Crossover Trial of Chitosan Oligosaccharide on Post Prandial Glucose Control in Subjects With Normal, IFG and IGT
It is well known that Chitosan oligosaccharide is low molecular weight and water soluble and chitosan oligosaccharide has been shown to reduce blood cholesterol and blood pressure, increase immunity, and enhance antitumor…
- Conditions
- Normal, Impaired Fasting Glucose, Impaired Glucose Tolerance
- Trial name
- NCT03650023
- Testing
- Chitosan Oligosaccharide (GO2KA1), White egg
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Diabetes Mellitus, Type 2
Acute Study of Effect of Ultrasound Vagus Nerve Stimulation on Glycemia
This is an early feasibility study to evaluate the proof of concept of modulation of glycemia by non-invasive ultrasound vagus nerve stimulation.
- Trial name
- NCT04094649
- Testing
- Ultrasound Vagus Nerve Stimulation (DECIMA)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Aucta Technologies, Inc.
Insulin Resistance, Type 2 Diabetes
Endothelial Function in Patients With Type 2 Diabetes Versus Healthy Subjects
The aim of the study is to evaluate the effect of hyperinsulinemia and postprandial changes in plasma glucose and lipids concentrations on the endothelial function together with other metabolic parameters in patients with type 2…
- Trial name
- EndoPat (NCT01946347)
- Testing
- mixed meal, Acute in vivo induced hyperinsulinemia
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical and Experimental Medicine
Pre-Diabetes
BTI320 (SUGARDOWN®) on Post-Prandial Hyperglycaemia in Subjects With Pre-Diabetes
This is a single-centre, 16-week, randomized, double-blind, placebo-controlled, 3-treatment arm pilot study to evaluate the efficacy and safety of BTI320 in the treatment of high risk subjects with pre-diabetes.
- Trial name
- NCT02358668
- Testing
- BTI320
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Diabetes Mellitus
A Randomized Control Trial Comparing Linjeta Versus Humalog in Pumps: Effect on Postprandial Blood Sugars.
The purpose of this study is to determine if the use of Linjeta(tm) insulin when compared to Humalog will result in significantly lower episodes of hyperglycemia and hypoglycemia after a breakfast meal.
- Trial name
- NCT01067118
- Testing
- LINjeta U-100 Insulin, Humalog U-100
- Where
- 2 sites in United States
- Sponsor
- Stanford University