Clinical trials: Hyperglycemia Steroid-induced
Pregnancy Preterm, Neonatal Hypoglycemia
Euglycemia After Antenatal Late Preterm Steroids, the E-ALPS Study
Annually in the U.S 300,000 neonates are born late preterm, defined as 34 weeks 0 days - 36 weeks 6 days. The Antenatal Late Preterm Steroids (ALPS) Trial demonstrated that maternal treatment with betamethasone in the late…
- Conditions
- Pregnancy Preterm, Neonatal Hypoglycemia, Hyperglycemia Drug Induced
- Trial name
- E-ALPS (NCT03076775)
- Testing
- Maternal glycemic control
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pre-diabetes, Impaired Fasting Glucose
Effect of Sitagliptin on Short-Term Metabolic Dysregulation of Oral Glucocorticoid Therapy
The investigators hypothesize that sitagliptin will significantly reduce impairments in insulin secretion and insulin resistance resulting from short-term oral glucocorticoid therapy.
- Conditions
- Pre-diabetes, Impaired Fasting Glucose, Impaired Glucose Tolerance
- Trial name
- NCT01488279
- Testing
- Dexamethasone 2.5 mg and Sitagliptin 100 mg
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Vermont