Clinical trials: Hyperinsulinism
Hyperlipidemia
The Effect of Intranasal Insulin on Hepatic and Intestinal Triglyceride-rich Lipoprotein Production
This study compares the effect of insulin given as a nasal spray with a placebo. Insulin is a chemical messenger (hormone) in the body that controls fat (triglyceride) levels in the blood by controlling the amount of fat made by…
- Trial name
- LPNI (NCT03141827)
- Testing
- Insulin
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Postmenopausal Disorder
Anthropometric, Metabolic, Cardiovascular and Symptomatic Profile in Postmenopausal Women
The purpose of this study is to investigate anthropometric, metabolic, cardiovascular and symptomatic profiles in postmenopausal women.
- Trial name
- NCT01745042
- Testing
- Clinical exams
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hypertension, Insulin Resistance
Caveolin-1 and Vascular Dysfunction
Caveolin-1 and Vascular Dysfunction Thank you for your interest in the investigators Blood Pressure Research Study. The National Institutes of Health are sponsoring us to investigate why patients develop high blood pressure…
- Trial name
- NCT01426529
- Testing
- Para-aminohippuric Acid, Angiotensin II, Norepinephrine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brigham and Women's Hospital
Essential Hypertension, Metabolic Syndrome
Vascular Impact of Omega-3 in Metabolic Syndrome
The overall aims of the present project are to investigate the impact of a nutritional approach based on omega-3 from vegetal origin on vascular function in hypertension associated with metabolic syndrome.
- Trial name
- CARDIOMEGA (NCT01566188)
- Testing
- omega-3 from vegetal origin
- Where
- 4 sites in France
- Volunteers
- 95 people
- Sponsor
- University Hospital, Rouen
Insulin Resistance
Investigation of Urinary Biomarkers for the Diagnosis of Insulin Resistance
The study aims at the identification and the quantification of urinary branched-chain amino acids (BCAAs) by mass spectometry in healthy subjects and patients with insulin resistance and correlating urinary BCAAs with HOMA index.
- Trial name
- BIOMUIR (NCT04010903)
- Testing
- assessment of biomarkers of insulin resistance
- Where
- France
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Metabolic Syndrome X
EFFECT OF Salvia Hispanica l. (CHIA) IN THE BIOCHEMICAL METABOLIC SYNDROME COMPONENTS
The objective of this study is to evaluate the effect of the administration of 25 g of chia per day, for 90 days on the biochemical components of the metabolic syndrome in subjects with this condition
- Trial name
- NCT02480673
- Testing
- Chia, Oatmeal, Normocaloric diet
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Instituto Mexicano del Seguro Social
Obesity, Insulin Resistance
Diabetes Prevention Program for Obese Latino Youth
The purpose of this study is to examine the effects of 12 week lifestyle intervention on diabetes risk in obese Latino adolescents.
- Conditions
- Obesity, Insulin Resistance, Diabetes
- Trial name
- ELSC (NCT02039141)
- Testing
- Every Little Step Counts Intervention
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Insulin Resistance
Safety, Pharmacokinetics and Potential Activity of HE3286 in Obese Adult Subjects
The objectives of this study are to evaluate the safety, tolerance and pharmacokinetics of HE3286 when administered daily for 28 days to obese adult subjects and to assess potential activity of HE3286 to decrease insulin…
- Trial name
- NCT00555451
- Testing
- HE3286
- Where
- 2 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Harbor Therapeutics
Overweight, Microbiota
Effects of Maple Syrup on Gut Microbiota Diversity and Metabolic Syndrome
It has been suggested that the actual obesity epidemy is related to chronic overconsumption of added or free sugars. The increasing popularity of artificial sweeteners attest the population willingness to reduce added sugars…
- Conditions
- Overweight, Microbiota, Endotoxemia, Metabolic Syndrome
- Trial name
- NCT04117802
- Testing
- Maple syrup
- Where
- Canada
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Laval University
Type 2 Diabetes
Egg Ingestion in Adults With Type 2 Diabetes
We propose a prospective, randomized, single-blind controlled crossover study to assess the effects of daily egg inclusion versus egg exclusion, on glycemic control, anthropometric measures, and overall diet quality in adults…
- Trial name
- NCT02052037
- Testing
- Egg inclusion, Egg exclusion
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Griffin Hospital
Metabolic Syndrome, Anesthesia
The Impact of Metabolic Syndrome on Patients Undergoing Elective Laparotomy
Worldwide, the rising incidence of obesity has led to the identification of an obesity related syndrome, called metabolic. This syndrome is characterized by central obesity, hypertension, insulin resistance and altered lipid…
- Conditions
- Metabolic Syndrome, Anesthesia, Perioperative Outcome, Complications
- Trial name
- NCT02447523
- Testing
- Elective abdominal surgery
- Volunteers
- 105 people
- Sponsor
- University of Ioannina
Overweight, Metabolic Syndrome X
Effects of NUTRIOSE®FB Dietary Fiber Supplementation on Satiety, Body Fat, and Metabolic Syndrome in Overweight Adult Men
The purpose of this study was to determine the effects of NUTRIOSE® supplementation on body composition, satiety, and determinants of metabolic syndrome in overweight men.
- Trial name
- NCT01044680
- Testing
- NUTRIOSE
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Roquette Freres
Cardiovascular Diseases, Diabetes
Kuopio Ischaemic Heart Disease Risk Factor Study (Nutrition Component)
To determine associations between dietary factors and risk of major chronic diseases and their risk factors
- Conditions
- Cardiovascular Diseases, Diabetes, Metabolic Syndrome, Cancer
- Trial name
- NCT03221127
- Volunteers
- 2,682 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Diabetes Mellitus, Type 2, Overweight and Obesity
Cut Down on Carbohydrate Usage in the Diet of Type 2 Diabetes. The Hypo-energetic Study
Scientific evidence for the dietary treatment of type 2 diabetes (T2D) is insufficient, which is why the investigators aim to reform dietary recommendation to the overweight or obese patient with type 2 diabetes.
- Trial name
- CutDM-Hypo (NCT03814694)
- Testing
- CRHP Diet, CD Diet
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Bispebjerg Hospital
Insulin Resistance, Obesity
Tea-beetroot-venous Occlusion Plethysmography
In the present study, muscle perfusion will be studied before and after an oral glucose challenge following a fasting period.
- Trial name
- NCT01746329
- Testing
- Tea, Beet root
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Chronic Kidney Disease, Insulin Resistance
Study of Vitamin D3 Supplementation in Patients With Chronic Kidney Disease
The purpose of this study is to evaluate the impact of vitamin D3 supplementation on the insulin resistance in non-diabetic patients with chronic kidney disease (CKD) stages 3-4, vitamin D deficiency/insufficiency and elevated…
- Conditions
- Chronic Kidney Disease, Insulin Resistance, Vitamin D Deficiency
- Trial name
- VitaD-CKD1 (NCT00893451)
- Testing
- cholecalciferol (TillVal-D)
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Sahlgrenska University Hospital
Insulin Resistance, Glucose Intolerance
Is Insulin Resistance and/or Glucose Intolerance Pathogenetic in the Development of a Reduced Incretin Effect
The purpose of this study is to examine whether there is a causal relationship between insulin resistance and/or glucose intolerance in the development of a defect incretin effect.
- Trial name
- NCT00784745
- Testing
- Dexamethasone
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Insulinoma
Laparoscopy to Remove Pancreatic Tumors (Insulinomas)
This study will determine if laparoscopy can be used successfully to find and remove insulinomas (insulin-secreting tumors of the pancreas).
- Trial name
- NCT00005910
- Testing
- Intraoperative ultrasound
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Overweight, Obesity
Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease
Since uncontrolled observational studies first linked fructose to the epidemic of obesity almost a decade ago, it has become a focus of intense concern regarding its role in the obesity epidemic and increasing burden of…
- Conditions
- Overweight, Obesity, Dyslipidemia, Hyperlipidemia
- Trial name
- NCT01608620
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Cardiometabolic Syndrome
Nutrition Education in Cardiac Rehabilitation
Coronary heart disease is one of the United Kingdom's biggest killers. In the UK alone 175,000 myocardial infarctions are recorded annually.
- Trial name
- NCT05198024
- Testing
- Nutrition knowledge
- Where
- United Kingdom
- Volunteers
- 64 people
- Sponsor
- Jonathan Sinclair