Clinical trials: Hyperlipoproteinemia
Familial Hypercholesterolemia, Atherosclerosis
Familial Hypercholesterolemia in Turkey (A-HIT2)
A-HIT2, is also designed as a National FH registry. At least 1000 FH patients will be recruited from 30 outpatient clinics representing the 12 Nuts statistical Regions in Turkey proportional to the 2015 Turkey's Population…
- Trial name
- A-HIT2 (NCT03110250)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Ege University
Non-familial Hypercholesterolemia and Mixed Hyperlipidemia
A Study to Evaluate the Safety, Efficacy of SYH2053 in Chinese Participants With Non-familial Hypercholesterolemia and Mixed Hyperlipidemia on a Background of Lipid-lowering Therapy
The purpose of this study is to compare the effectiveness, safety of SYH2053 in participants with primary hypercholesterolemia (non-familial) or mixed dyslipidemia on a background of lipid-lowering therapy.
- Trial name
- NCT07421284
- Where
- China
- Volunteers
- 900 people
- Sponsor
- CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
Diabetes Mellitus, Hypertension
Reducing Clinical Inertia in Diabetes Care
In this randomized trial we evaluate two conceptually distinct but potentially synergistic interventions designed to reduce clinical inertia in the outpatient care of adults with type 2 diabetes.
- Conditions
- Diabetes Mellitus, Hypertension, Hyperlipidemia
- Trial name
- NCT00272402
- Testing
- Cognitive Behavioral Intervention, Office System Redesign Intervention
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Vascular Disease, Diabetes
The Epidemiology of Aortic Diameter in China
Aortic aneurysms are the major disease processes affecting the aorta and becoming a relatively common cause of death because of rupture or dissection.
- Conditions
- Vascular Disease, Diabetes, Hypertension, Hyperlipidemia
- Trial name
- NCT00820378
- Testing
- No special interventioin
- Where
- 2 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Zhejiang University
Homozygous Familial Hypercholesterolemia (HoFH)
A Dose-exploration Study of EDP167 in HoFH
EDP167 is a double-stranded small interfering RNA (siRNA) drug targeting angiopoietin-like 3 protein (ANGPTL3), which may bring benefits for patients with dyslipidemia conditions.
- Trial name
- NCT07489209
- Testing
- EDP167
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Eddingpharm (Zhuhai) Co., Ltd.
Peripheral Arterial Disease
Effect of Evolocumab in Functional Status and LDL Oxidation of Patients With Peripheral Arterial Disease
Peripheral arterial disease (PAD) is a manifestation of systemic atherosclerotic cardiovascular disease (ASCVD) and is associated with increase cardiovascular risk.
- Trial name
- Evol-PAD (NCT04306081)
- Testing
- Evolocumab 140 mg/mL Subcutaneous Injection 1 milliliter (mL) pre-filled injector Pen x 3 for a monthly dose of 420 mg for 6 months.
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Leonardo Clavijo
Diabetes, Hyperlipidemia
The Health Outcomes Management and Evaluation (HOME) Study
There is an urgent need to develop practical, sustainable approaches to improving medical care for persons treated in community mental health settings.
- Conditions
- Diabetes, Hyperlipidemia, Heart Disease, High Blood Pressure
- Trial name
- HOME (NCT01228032)
- Testing
- Care team
- Where
- United States
- Volunteers
- 447 people
- Sponsor
- Emory University
Hyperlipidemia
Differential Effects of a Diet Supplementation With Plant Sterol Esters on Human Monocytes
The purpose of this study is to evaluate the effects of a diet supplementation with plant sterol esters on serum lipids, plant sterol concentrations and monocyte subpopulations.
- Trial name
- PSE-MO (NCT00928616)
- Testing
- margarine + plant sterol esters
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Saarland
Obese, Hyperlipidemia
Effects of Green Tea Extract on Obese Women With High Level of LDL
Green tea is one of the most popular beverages in the world. It is believed to have beneficial effect in prevention and treatment of many diseases, one of which is reducing LDL-C.
- Trial name
- GTE-LDL (NCT02116517)
- Testing
- green tea extract
- Where
- Taiwan
- Volunteers
- 73 people
- Sponsor
- National Yang Ming Chiao Tung University
Diabetes Mellitus
Prospective Evaluation of Proteinuria and Renal Function in Diabetic Patients With Progressive Renal Disease
The purpose of this study is to evaluate the effects of Crestor (rosuvastatin) and (Lipitor) atorvastatin on urinary protein excretion over 1 year in patients with Type 1 or 2 diabetes with moderate proteinuria and…
- Trial name
- PLANET 1 (NCT00296374)
- Testing
- Rosuvastatin, Atorvastatin
- Where
- 116 sites in United States, Argentina and 9 more
- Volunteers
- 353 people
- Sponsor
- AstraZeneca
Obesity, Overweight
Eating Peanuts for Health
Evidence is accumulating that peanut consumption confers health benefits, such as reduction of cardiovascular disease risk and possibly diabetes risk (Jenkins et al., 2008; Mattes et al., 2008).
- Conditions
- Obesity, Overweight, Hyperlipidemia
- Trial name
- NCT01886326
- Testing
- Consumption of 42 grams of peanuts daily
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Purdue University
Coronary Artery Disease
Prevalence of Familial Hypercholesterolaemia (FH) in Italian Patients With Coronary Artery Disease
Evaluate the prevalence of familial hypercholesterolemia (FH) in patients with documented coronary artery disease (CAD) event [acute myocardial infarction (AMI), acute coronary syndrome (ACS), coronary artery bypass graft (CABG)…
- Trial name
- POSTER (NCT03520140)
- Where
- 81 sites in Italy
- Volunteers
- 5,415 people
- Sponsor
- Heart Care Foundation
Diabetes, Hyperlipidemia
Expanding Comparative Effectiveness Research (CER) Capability Through Complex Patient Relationship Management
The investigators are testing whether patients with diabetes can communicate with our health care system through text messaging.
- Trial name
- NCT01391585
- Testing
- Text Message prompts
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Denver Health and Hospital Authority
Hypolipoproteinemia, Hypercholesterolemia
Lipoprotein Metabolism in Normal Volunteers and Patients With High Levels of Lipoproteins
Researchers plan to study the fat-rich particles, called lipoproteins, which circulate in the blood. This study is designed to improve understanding of normal, as well as abnormal, lipoprotein metabolism and the role it plays in…
- Conditions
- Hypolipoproteinemia, Hypercholesterolemia, Dyslipidemia, Hyperlipidemia
- Trial name
- NCT00001154
- Where
- United States
- Volunteers
- 759 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypercholesterolemia
Efficacy of Lapaquistat Acetate Alone or Combined With Rosuvastatin in Subjects With Hypercholesterolemia
The purpose of this study is to evaluate lapaquistat acetate, once daily (QD), taken alone or with rosuvastatin on cholesterol levels in treating patients with elevated cholesterol.
- Trial name
- NCT00249912
- Testing
- Lapaquistat acetate and rosuvastatin, Rosuvastatin
- Where
- 92 sites in United States, Canada
- Volunteers
- 415 people
- Sponsor
- Takeda
Cardiometabolic Disease, Hyperlipidemia
Telehealth Integrated Care Model in Patients With Cardiometabolic Disease
The objective of this study is to evaluate the telehealth integrated care model for its clinical efficacy, medical resource utilization, health economics measurement, and satisfaction survey indicators in hyperlipidemia patients…
- Trial name
- NCT06022575
- Testing
- Telehealth integrated care, Conventional health care
- Where
- China
- Volunteers
- 1,302 people
- Sponsor
- Peking University Third Hospital
Familial Hypercholesterolemia, Cholesterol, Elevated
Improved Diagnosis of Familial Hypercholesterolemia Across the Northland (ID-FH)
The overall goal of this study is to promote awareness of Familial Hypercholesterolemia (FH). The investigators aim to enroll patients with suspected FH into the study and will randomize them to receive usual care or motivational…
- Conditions
- Familial Hypercholesterolemia, Cholesterol, Elevated, Genetic Disease
- Trial name
- ID-FH (NCT05238519)
- Testing
- Motivational interview (MI)
- Where
- 2 sites in United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Essentia Health
Homozygous Familial Hypercholesterolemia (HoFH)
A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of VSA003 in Chinese HoFH Patients
Significant reduction in ANGPLT3 levels is expected to reduce plasma LDL-C and TG levels and may lead to the reduction of risk of coronary heart disease and cardiovascular events associated with hypertriglyceridemia and LDL-C in…
- Trial name
- NCT06712771
- Testing
- VSA003
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Visirna Therapeutics HK Limited
Homozygous Familial Hypercholesterolemia (HoFH)
Identifying and Genotyping Homozygous Familial Hypercholesterolemia (HoFH) Patients
This study is designed to help identify patients with HoFH due to mutations in the LDLR as confirmed by genotyping.
- Trial name
- NCT04148001
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- REGENXBIO Inc.
Type 2 Diabetes Mellitus (T2DM), Type 2 Diabetes
Osaka Cardiometabolic Epidemiological Study: Ohtori Study Part 2
The aim of this study is to investigate the relationship between body fat distribution measured by CT scan and related risk factors with the risk of incident metabolic and cardiovascular disease in a prospective cohort study of…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Type 2 Diabetes, Diabetes Mellitus, Hypertension
- Trial name
- OCES-2 (NCT06694012)
- Where
- Japan
- Volunteers
- 2,000 people
- Sponsor
- Osaka Metropolitan University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.