Clinical trials: Hyperplasia
Benign Prostatic Hyperplasia, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
A Phase III Clinical Study of H077 Sustained-Release Tablets Compared With Silodosin Capsules in the Treatment of Benign Prostatic Hyperplasia
This is a randomized, double-blind, controlled, non-inferiority multicenter Phase III clinical study to evaluate the efficacy and safety of H077 sustained-release tablets versus silodosin capsules in treating benign prostatic…
- Trial name
- NCT07146386
- Testing
- H077 sustained-release tablet, Silodosin capsules Control Group
- Where
- 66 sites in China
- Volunteers
- 728 people
- Sponsor
- Shanghai Huilun Pharmaceutical Co., Ltd.
Benign Prostate Hyperplasia
A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of HGP0412 and HIP1402 in Patients With BPH
The main objective of this study is to evaluate efficacy and safety of (Tamsulosin) HGP0412 and HIP1402 in patients with Benign Prostatic Hyperplasia
- Trial name
- NCT02390882
- Testing
- HGP0412 capsule, HIP1402 capsule
- Where
- South Korea
- Volunteers
- 494 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Benign Prostate Hyperplasia
Efficacy and Safety of Tamsulosin/Solifenacin Combination Therapy in Patients With Voiding Symptoms and Moderate to Severe Storage Symptoms Due to Benign Prostate Hyperplasia
Efficacy and Safety of Tamsulosin/Solifenacin Combination therapy in Patients with voiding symptoms and moderate to severe storage symptoms due to Benign Prostate Hyperplasia : a randomized, double blinded, parallel design…
- Trial name
- NCT02827578
- Testing
- Tamsulosin, Solifenacin
- Where
- South Korea
- Volunteers
- 588 people
- Sponsor
- IlDong Pharmaceutical Co Ltd
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Research for the Efficacy and Safety of Percutaneous Tibial Nerve Stimulation to Promote Storage Symptoms Postoperative Recovery for Patients With Benign Prostatic Hyperplasia
The goal of this clinical trial is to guide and promote the clinical application of T-PTNS in promoting the postoperative recovery of urinary storage symptoms in patients with BPH.
- Trial name
- NCT06742489
- Testing
- Percutaneous tibial nerve stimulation device
- Volunteers
- 160 people
- Sponsor
- Zhu Yiping
Benign Prostate Hyperplasia
Prostatic Artery Embolization for Benign Prostatic Hyperplasia
To evaluate whether Prostatic Artery Embolization (PAE) might be an effective alternative treatment option for benign prostatic hyperplasia (BPH), in comparison to current gold standard surgical treatment- Transurethral Resection…
- Trial name
- NCT01835860
- Testing
- Prostate artery embolization
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Saskatchewan Health Authority - Regina Area
Benign Prostatic Hyperplasia
Ultrasound-Guided vs. Conventional Prostate Suspension in BPH: An Exploratory Study
This is an exploratory, prospective, single-center, open-label, 1:1 randomized controlled study. The study compares two surgical methods for benign prostatic hyperplasia (BPH): ultrasound-guided prostate suspension and…
- Trial name
- NCT07873125
- Testing
- Ultrasound-Guided Prostatic Urethral Lift, Conventional Prostatic Urethral Lift
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai East Hospital
Breast Cancer
Protocol for Women at Increased Risk of Developing Breast Cancer
A pilot study to assess the effects of six months of letrozole on breast tissue risk markers in postmenopausal women on hormone replacement therapy at high risk of developing breast cancer.
- Trial name
- NCT00291135
- Testing
- letrozole
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Carol Fabian, MD
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Evaluation of Symptom-specific Goal Achievement
Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) consists of a constellation of symptoms (including voiding, storage, and post-micturition).
- Trial name
- NCT00836823
- Testing
- Alfuzosin
- Where
- 2 sites in South Korea
- Volunteers
- 130 people
- Sponsor
- Samsung Medical Center
Prostatic Hyperplasia, Prostate
Study to Determine Safety and Effectiveness of Tadalafil on Prostate Related Sex Organ/Urinary Tract Problems
Study to look at safety and effectiveness of different doses of tadalafil on prostate related genital/urinary tract problems.
- Trial name
- PILUTS (NCT00547625)
- Testing
- tadalafil
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- Eli Lilly and Company
Prostatic Hyperplasia, Benign, Prostatic Obstruction
HoLEP: Learning Curve Analysis and Comparison With TURP
This study evaluates the outcomes of Holmium laser enucleation of the prostate (HoLEP) during both the learning and expert phases compared to transurethral resection of the prostate (TURP) in managing benign prostatic obstruction…
- Trial name
- NCT06849089
- Testing
- Transurethral resection of prostate (TURP), Holmium laser enucleation of prostate
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University
Benign Prostatic Hyperplasia
A Study in Benign Prostatic Hyperplasia
The purpose of this trial is to evaluate the effect of tadalafil 5 milligrams (mg) daily for 8 weeks compared to placebo on prostatic blood perfusion in men with signs and symptoms of Benign Prostatic Hyperplasia (BPH), measured…
- Trial name
- NCT01152190
- Testing
- Tadalafil
- Where
- 5 sites in United States, Austria and 1 more
- Volunteers
- 97 people
- Sponsor
- Eli Lilly and Company
Urosepsis, Bladder Cancer
Antibiotic Prophylaxis in Transurethral Prostate Resection (TURP) and Transurethral Bladder Tumour Resection (TURB)
To investigate the use of antibiotic prophylaxis in patients undergoing TURP and TURB. The investigators set up a prospective, randomized controlled trial in which (after exclusion of risk factors) patients will be randomized in…
- Conditions
- Urosepsis, Bladder Cancer, Prostate Hyperplasia, Antibiotic Resistant Strain
- Trial name
- Prophylaxis001 (NCT04212403)
- Testing
- Levofloxacin
- Where
- Belgium
- Volunteers
- 1,350 people
- Sponsor
- Jessa Hospital
Prostatic Hyperplasia, Impotence
Effect of Vardenafil on Blood Pressure in Patients With Erectile Dysfunction Who Received Concomitant Doxazosin GITS
The purpose of this study is to investigate the interaction between doxazosin GITS and vardenafil on blood pressure (Both systolic and diastolic blood pressure) in patients with both ED and BPH.
- Trial name
- NCT00517179
- Testing
- Vardenafil 10mg
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Hospital Authority, Hong Kong
Benign Prostatic Hyperplasia
Clinical Trial To Evaluate the Efficacy and Safety of CKD-397 in Benign Prostatic Hyperplasia Patients
A Multicenter, Randomized, Double-blind, Active-controlled, Parallel group, Phase III Clinical Trial To Evaluate the Efficacy and Safety of CKD-397 in Benign Prostatic Hyperplasia Patients.
- Trial name
- NCT03246880
- Testing
- Tamsulosin 0.2mg, Tadalafil 5mg
- Where
- South Korea
- Volunteers
- 455 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Chronic Rhinosinusitis With Polyposis, Chronic Hyperplastic Sinusitis
Intravenous Tranexamic Acid and Intraoperative Visualization During Functional Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is an effective treatment of sinus disease. FESS is carried out using cameras to view the surgical field. Bleeding during the surgery can lead to poor surgical field visualization.
- Trial name
- NCT01111669
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Mouth Diseases
Evaluation of Oral Potentially Malignant Disorders (OPMDs) with STRATICYTE™
The purpose of this study is to validate the ability of the STRATICYTE™ predictive model to predict the transformation of oral potentially malignant disorders (OPMDs) to oral squamous cell carcinoma (OSCC) in a retrospective…
- Trial name
- NCT05853783
- Testing
- STRATICYTE™ Test
- Where
- 5 sites in United States
- Volunteers
- 180 people
- Sponsor
- Proteocyte Diagnostics Inc.
Endometrial Cancer, Cervical Cancer
Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer
The overarching objective of this project is to develop a pan-gynecologic cancer detection test using gynecologic (unique endometrial, cervical, and ovarian cancer) cancer-specific methylated DNA markers and high-risk human…
- Conditions
- Endometrial Cancer, Cervical Cancer, Atypical Endometrial Hyperplasia, Cervical Dysplasia
- Trial name
- ECHO (NCT05051722)
- Testing
- Vaginal Fluid Collection, Blood Collection
- Where
- 25 sites in United States
- Volunteers
- 3,110 people
- Sponsor
- Mayo Clinic
Nocturia, Benign Prostatic Hypertrophy (BPH)
Dose Response Study of VA106483 in Males With Nocturia and Benign Prostatic Hypertrophy (BPH)
The purpose of this study is to establish the dose response relationship of VA106483 and nocturnal urine volumes in a population of elderly male subjects with Benign Prostatic Hypertrophy (BPH) who are likely to present with…
- Trial name
- NCT01330927
- Testing
- VA106483
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Vantia Ltd
Bladder Cancer
Comparison of Medical and Surgical Treatments of Benign Prostate Hyperplasia in Patients Who Have Low Grade Non Muscle Invasive Bladder Cancer for Tumour Recurrence and Progression
The purpose of this study is to compare medical and surgical treatments of benign prostate hyperplasia in patients who have non muscle invasive bladder cancer for tumour recurrence and progression.
- Trial name
- NCT02443844
- Testing
- Transurethral Resection, Tamsulosin
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Diskapi Teaching and Research Hospital
Benign Prostatic Hyperplasia
IIT-2022-Simultaneous Urolift™ and Median Lobe Enucleation
To evaluate postoperative outcomes of BPH/Lower urinary tract symptoms, erectile function, and ejaculatory capacity of simultaneous UroLiftTM and Holmium laser enucleation of the prostatic median lobe.
- Trial name
- NCT06157164
- Testing
- UroLift™ System and Holmium Laser Enucleation of the Prostate (HoLEP)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Kansas Medical Center