Clinical trials: Hypersensitivity, Food
Peanut Allergy
Validation of the HYPONUT Product
The HYPONUT product was previously validated in a laboratory setting ("Procédé de préparation d'aliment hypoallergénique", n° FR1250977) on 2012. A international patent was then obtained on 2013.
- Trial name
- NCT03849079
- Testing
- Hyponut
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Montpellier
Wheat Allergy
Oral Immunotherapy for Wheat Allergy
This study is being done to learn about the medical effects, the safety, and the immunologic effects of Wheat Oral Immunotherapy (OIT) treatment.
- Trial name
- Wheat OIT (NCT01980992)
- Testing
- Wheat OIT
- Where
- 4 sites in United States
- Volunteers
- 46 people
- Sponsor
- Hugh A Sampson, MD
Food Allergies
Omalizumab for Plant-Food Allergy Due to Sensitization to LTP or Profilin
Omalizumab has demonstrated efficacy, increasing the tolerance threshold in patients with multiple food allergies, as well as reducing the risk of severe reactions when used as monotherapy.
- Trial name
- Omlyclo (NCT07073404)
- Testing
- Omalizumab Injection
- Volunteers
- 37 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Food Allergy
Infants Fed an Amino Acid-based Formula
To observe the effects of an amino acid-based formula on symptoms associated with food allergies in infants.
- Trial name
- NCT04127656
- Testing
- Amino Acid-Based Experimental Study Formula
- Where
- 3 sites in United Kingdom
- Volunteers
- 26 people
- Sponsor
- Abbott Nutrition
Eosinophilic Esophagitis
Targeted Elimination Diet in EoE Patients Following Identification of Trigger Nutrients Using Confocal Laser Endomicroscopy
Using confocal laser endomicroscopy (CLE), gastrointestinal allergic reactions to certain foods in the duodenum will be evaluated on a cellular level.
- Trial name
- CLE-EoE (NCT05695456)
- Testing
- personalized exclusion diet based on CLE, empiric exclusion diet
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cirrhosis, Food Preferences
Feeding Behavior and Taste Sensitivity Before and After Liver or Renal Transplantation
This study evaluates the influence of the taste sensitivity, of food preferences and of the reward system on the energetic balance before and after liver transplantation in cirrhotic patients and after kidney transplantation in…
- Conditions
- Cirrhosis, Food Preferences, Taste Disorders, Protein-Energy Malnutrition
- Trial name
- GREFFE (NCT02931812)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Burgundy
Hypersensitivity, Food
Prospective Study About Sensitization Pattern to Insects as Food Source in Patients With House Dust Mite Allergy
Patients allergic to seafood and/or sensitized to Tropomyosin of Skin Prick tests SPT or crustacean origin will may be also be sensitized to edible insects.
- Trial name
- InFood (NCT04239131)
- Testing
- Skin prick test
- Where
- Switzerland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Asthma
A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of AZD9898
In this integrated, multi-part, Phase I study, the safety, tolerability, food effect, pharmacokinetic (PK) and pharmacodynamic (PD) properties of single and repeated doses of AZD9898 will be investigated.
- Trial name
- NCT03140072
- Testing
- AZD9898
- Where
- 2 sites in United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Nutrient Deficiency, Eating Behavior
The Effect of Early Childhood Cow's Milk Allergy Elimination Diet on Eating Behaviors, Nutrition, and Growth Status
Cow's milk allergy (CMA) is the most common Food Allergy (FA) in children, and the essential strategy in prevention is avoiding the allergens that may cause potentially life-threatening reactions.
- Conditions
- Nutrient Deficiency, Eating Behavior, Cow Milk Allergy, Growth Disorders
- Trial name
- NCT04576845
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Saglik Bilimleri Universitesi
Cow's Milk Allergy
Diagnosis of Cow's Milk Protein Allergy
The study will assess the diagnosis of cow's milk protein allergy (CMPA) among infant and children in assiut university children hospital using skin prick test and specific serum IgE as well as their management.
- Trial name
- NCT04330092
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Systemic Nickel Allergic Syndrome
Telemedicine for SNAS Patients in COVID-19 Pandemic
Restrictions due to Covid-19 pandemic have brought negative social and psychological consequences on people and limited patients' access to hospital care.
- Trial name
- DISTANCE (NCT04894331)
- Testing
- Dietary intervention, Video call
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Catholic University of the Sacred Heart
Allergy, Asthma
Evaluation and Long-Term Follow-Up of Patients With Allergic and Inflammatory Disorders
This study will evaluate and follow patients with various allergic, hypersensitivity and inflammatory disorders. The protocol is not designed to test new treatments; patients will be managed with standard of care therapies.
- Conditions
- Allergy, Asthma, Allergic Rhinitis, Mastocytosis
- Trial name
- NCT00557895
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Egg Allergy
Safe Administration of Flu Vaccine to Egg Allergic Children
Historically, providing influenza vaccination of egg allergic children and young adults (EAC) with a history of anaphylaxis to egg, or other severe symptoms of an allergic reaction to egg (e.g., severe hives, swelling, or…
- Trial name
- SAFE (NCT01264601)
- Testing
- Trivalent Influenza Vaccine
- Where
- 5 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Michigan
Peanut Allergy
PALISADE Follow-on Study (ARC004)
The purpose of this study is to demonstrate the safety, tolerability, and efficacy of AR101 through oral immunotherapy (OIT) in peanut-allergic children and adults who have completed the ARC003 study.
- Trial name
- NCT02993107
- Testing
- AR101
- Where
- 65 sites in United States, Canada and 7 more
- Volunteers
- 388 people
- Sponsor
- Aimmune Therapeutics, Inc.
Fasting, Fed
Development of the Leeds Food Preference Questionnaire in Spanish
The Leeds Food Preference Questionnaire (LFPQ) is a computer-based task used to measure reward responses and preferences for images of food.
- Trial name
- ES-LFPQ (NCT05837572)
- Testing
- Standardized meal
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Individual Difference, Food Sensitivity
Modifying Whey Protein Fortified Drinks and Foods
This study aims to investigate whether consumers differ in mouthdrying sensitivity and if mouthdrying can be modulated.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04869722
- Testing
- Liquid Model, Solid Model
- Where
- United Kingdom
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Reading
Peanut Allergy
Study of ENP-501 in Peanut-Allergic and Non-Allergic Participants
This is a Phase 1/2 study to evaluate the safety and clinical activity of ENP-501 in non-peanut allergic (NPA) healthy participants and participants with an established peanut allergy (PA)
- Trial name
- NCT07117669
- Testing
- ENP-501
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- N-Fold, LLC
Hypersensitivity, Allergy, Egg
Hypersensitivity Reactions to Propofol in Children
The investigators would only include the children who received propofol (Propolipid, Fresenius Kabi, Schelle, Belgium) for sedation, the investigators would exclude the children that didn't receive propofol during the procedure.
- Conditions
- Hypersensitivity, Allergy, Egg, Soy Allergy
- Trial name
- NCT04839666
- Testing
- Propofol
- Where
- Belgium
- Volunteers
- 2,299 people
- Sponsor
- Universitair Ziekenhuis Brussel
Food Allergy
E-B-FAHF-2, Multi OIT and Xolair for Food Allergy
The purpose of this study is testing the use of Enhanced-Butanol purified-Food Allergy Herbal Formula-2 (E-B-FAHF-2) Chinese herbal therapy in combination with multi-food oral immunotherapy (OIT) and Xolair® (Omalizumab) to help…
- Trial name
- FAHF-2 (NCT06103656)
- Testing
- Drug: Chinese Herbal Medication, Drug: Omalizumab
- Volunteers
- 33 people
- Sponsor
- New York Medical College
Peanut Allergy
Oral Immunotherapy for Young Children With Peanut Allergy - Small Children OIT
Open label study with peanut oral immunotherapy (OIT). Peanut allergic children aged 1-3 years of age will be randomized 2:1 to: 1.
- Trial name
- SmaChO (NCT04511494)
- Testing
- Peanut (bamba)
- Where
- Sweden
- Volunteers
- 114 people
- Sponsor
- Karolinska Institutet