Clinical trials: Hypersensitivity, Food
Food Allergy
Efficacy of Cashew Nut Protein Immunotherapy
It is a randomized, single-center, controlled trial to evaluate the effectiveness of oral immunotherapy with cashew protein compared with standard treatment (elimination diet) in pediatric patients with cashew allergy.
- Trial name
- NCT06328504
- Testing
- Cashew immunotherapy
- Where
- Poland
- Volunteers
- 39 people
- Sponsor
- Medical University of Warsaw
Microbiome, Stress
Investigating the Detection of Bovine and Soy Proteins in Human Milk
This study is a randomized, cross-over, dietary intervention research design comprising a 5-day run-in period, two 3-day dietary interventions, and a 2-day washout period.
- Conditions
- Microbiome, Stress, Food Allergy in Infants
- Trial name
- NCT04851340
- Testing
- Cow's Milk, Soy Milk
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Idaho
Food Allergy in Children, Food Allergy
Virtual Reality Technology Versus Standard Technology During Pediatric Oral Food Challenge
The purpose of this study is to determine if non-invasive distracting devices (Virtual Reality headset) are more effective than the standard of care of utilizing existing technologies that are currently more common in food…
- Trial name
- NCT04376242
- Testing
- use of virtual reality, use of standard technology
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Stanford University
Food Allergy, Anaphylaxis Food
Inhibition of Anaphylaxis by Ibrutinib
This is a phase II open label study on the use of Ibrutinib on the inhibition of food-induced anaphylaxis in adults with food allergy.
- Trial name
- NCT03149315
- Testing
- Ibrutinib
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Cow's Milk Allergy
Evaluation of Tolerance, Efficacy and Safety of an Hydrolyzed Formula in Infants With IgE/Non-IgE Mediated CMA.
The aim of this interventional study is to assess the hypoallergenicity of a new formula in infants having a cow milk allergy (CMA), whatever the type of CMA, meaning in both IgE-mediated and non-IgE-mediated CMA patients.
- Trial name
- MERLIN (NCT06481280)
- Testing
- Test Formula
- Where
- 2 sites in Belgium, Italy
- Volunteers
- 70 people
- Sponsor
- United Pharmaceuticals
Venous Thromboembolism, Atopic Dermatitis
The Incidence of Venous Thromboembolism in Atopic Dermatitis
This study aims to investigate the incidence of venous thromboembolism in people who are diagnosed with atopic dermatitis.
- Conditions
- Venous Thromboembolism, Atopic Dermatitis, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- NCT04969653
- Testing
- Exposure of venous thromboembolism
- Where
- United Kingdom
- Volunteers
- 754,745 people
- Sponsor
- Momentum Data
Cow Milk Allergy, Food Allergy
Clinical Versus Home Introduction of Milk in Children with Non-IgE-mediated Cow's Milk Allergy
There are a lot of parents who believe that their child may not tolerate cow's milk because they develop symptoms such as redness of the skin or they may vomit.
- Trial name
- ENIGMA (NCT05785299)
- Testing
- Cow's milk, Home introduction
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Martini Hospital Groningen
Food Allergy
Efficacy and Safety of Viaskin Milk in Children With IgE-Mediated Cow's Milk Allergy
The objectives of this study are to evaluate the safety and efficacy of Viaskin Milk after 12 months of epicutaneous immunotherapy (EPIT) treatment, for desensitizing IgE-mediated cow's milk allergic children and to assess the…
- Trial name
- MILES (NCT02223182)
- Testing
- Viaskin Milk 150 mcg, Viaskin Milk 300 mcg, Viaskin Milk 500 mcg
- Where
- 17 sites in United States, Canada
- Volunteers
- 198 people
- Sponsor
- DBV Technologies
Child Allergy, IgE-Mediated Allergic Process
Observatory of the Lille Paediatric Allergy Unit
The goal of this study is to set up a paediatric observatory within the allergology department of The saint Vincent Hospital, Lille.
- Conditions
- Child Allergy, IgE-Mediated Allergic Process, Food Allergy
- Trial name
- PAUL (NCT06634992)
- Testing
- Oral immunotherapy
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Lille Catholic University
Eosinophilic Disorder, Food Allergy
Gastrointestinal STRING Test With Oral Immunotherapy
This STRING study will examine markers of esophageal inflammation using a minimally-invasive testing device, the esophageal string test (EST).
- Trial name
- STRING (NCT04943744)
- Testing
- Entero-tracker, omalizumab, dupliumab
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Stanford University
Allergy, Food Allergy
Threshold Dose Distribution for Pistachio Allergy
The main objective of this study is to describe the distribution of reactogenic thresholds for pistachio. The secondary objectives are to 1) describe the clinical severity of allergic reactions to pistachio in an oral challenge…
- Trial name
- NCT06589232
- Testing
- Food allergy
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
FOOD ALLERGY, FOOD ALLERGY İN CHİLDREN
Evaluation of the Effect of Life With Food Allergy Education
Purpose of the Study It was aimed to reveal the changes in the knowledge levels of mothers with food allergy with Life with Food Allergy Education based on Pender's Health Promotion Model.
- Trial name
- NCT06509737
- Testing
- Face to face group, social mediagroup
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Food Allergy
The Basophil Activation Test For Egg Allergy
In this study, basophil activation test (BAT) established by the investigators' lab was evaluated for its sensitivity and specificity in child egg allergy diagnosis.
- Trial name
- BAT (NCT06559319)
- Testing
- blood sampling
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Xia Peng
Food Allergy
Improvement of Foodallergy Diagnostic in Gastrointestinal Tract
Currently, diagnostic possibilities for the detection of food allergy in the gastrointestinal tract are scarce. The endoscopic segmental Lavage is the method of choice, but it´s controversial.
- Trial name
- NCT03151252
- Testing
- Cytobrush
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Food Allergy, Food Hypersensitivity
Mucosal IgE to Improve Diagnosis of Food Allergy and Food Hypersensitivity
Aim of the study is to improve the diagnosis of food allergy and hypersensitivity. Intestinal homogenates will be used to determine total IgE, specific IgE, tryptase, histamine and inflammation parameters (IFNgamma, TNFalpha).
- Trial name
- NCT05259826
- Testing
- biopsy sampling
- Where
- Germany
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Allergy Milk, Allergy;Food
Dietary Choice for the Management of Cow's Milk Allergy Influences Other Allergic Manifestations
Food allergy is a common chronic condition in childhood. Recent studies have suggested that the natural history of food allergy has changed during the last two decades, with an increased prevalence, severity of clinical…
- Conditions
- Allergy Milk, Allergy;Food, Allergic Asthma, Allergic Conjunctivitis
- Trial name
- ATMAII (NCT03861910)
- Testing
- hypoallergenic formulas
- Where
- Italy
- Volunteers
- 365 people
- Sponsor
- Federico II University
Food Allergy
Observatory on Cow's Milk Protein Allergy
The purpose of this study is to describe the symptoms and their evolution up to the age of 5 years in a population of newly diagnosed infants with a suspected or confirmed allergy to cow proteins, for whom the doctor prescribed…
- Trial name
- OLAF (NCT06085118)
- Testing
- Pepticate® Syneo®
- Where
- 2 sites in France
- Volunteers
- 3,000 people
- Sponsor
- Nutricia Nutrition Clinique
Food Allergy
Allergenicity Assessment of Green Marine Macroalga Ulva sp.
To determine the allergenic potential in humans, we will conduct a three-stage clinical trial. In the first group, 20 healthy volunteers will be involved.
- Trial name
- NCT06452381
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Tree Nut Allergy, Food Allergy
TRADE Trial - Tree Nut Immunotherapy Route Development and Evaluation
Tree nut immunotherapy Route Assessment and DEvelopment (TRADE) is a randomized controlled trial that evaluates the efficacy and safety of sublingual immunotherapy and lower, more tolerable, doses of oral immunotherapy than…
- Trial name
- TRADE (NCT05521711)
- Testing
- Food
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Tree Nut Allergy, Food Allergy
Thresholds In Food Allergy evaluaTion And predictioN
Thresholds In food allergy evaluaTion And predictioN, a prospective, observational registry. The aim is to quantify food allergy thresholds in Canada and their clinical predictors.
- Trial name
- TITAN (NCT06038019)
- Testing
- Oral food challenge
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation