Clinical trials: Hypersensitivity, Food
Cow's Milk Allergy, Atopic Disease
Effect Of Lactobacillus GG on Atopic March
Food allergy (FA), defined as an adverse immune response to food allergens, is among the most frequent allergic disorders in childhood and it has recognized as a major paediatric health problem due to the severity of the…
- Trial name
- NCT01891916
- Testing
- Extensively hydrolyzed casein formula + LGG
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Federico II University
Fish Allergy, Food Allergy in Children
Fish Oral Immunotherapy in Hong Kong Children
At present there is no cure for food allergy. People with a food allergy need to avoid the food they are allergic to in order to stay safe, but we know that accidental exposure is common.
- Trial name
- NCT05590299
- Testing
- Fish oral immunotherapy (codfish)
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- Chinese University of Hong Kong
Allergy
Follow up of Patients After Oral Immunotherapy for Cow's Milk, Eggs and Peanuts
Food allergy is a potentially life threatening condition. The current practice consists of elimination diet and injectable epinephrine in case of a reaction.
- Trial name
- OIT followup (NCT01999387)
- Testing
- Allergenic food
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Assaf-Harofeh Medical Center
Eosinophilic Esophagitis
Food Antigen in Eosinophilic Esophagitis
The relationship or effect of food antigen (wheat based soy sauce) in eosinophilic esophagitis. It is believed that when food antigens are exposed to the esophageal tissue it starts an chronic allergy-based inflammation.
- Trial name
- EoE (NCT02434705)
- Testing
- Antigen (wheat base soy sauce) spray
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Mayo Clinic
Milk Allergy
OIT and Xolair® (Omalizumab) in Cow's Milk Allergy
Food allergy affects up to 4% of the U.S. population and is most common in young children. Milk allergy is the most common cause of food allergy in infants and young children, and usually develops in the first year of life.
- Trial name
- NCT01157117
- Testing
- Omalizumab, Milk powder
- Where
- 3 sites in United States
- Volunteers
- 77 people
- Sponsor
- Hugh A Sampson, MD
Digestive Health, Gastrointestinal Health
The Effects of Oral Fructanase Administration on Gastrointestinal Symptoms After Inulin Challenge in Healthy Adults
The carbohydrate inulin (from chicory root) is a healthy prebiotic ingredient found in dietary supplements and fortified foods (Nagy et al).
- Conditions
- Digestive Health, Gastrointestinal Health, FODMAP Intolerance, Food Sensitivity
- Trial name
- NCT06628869
- Testing
- Fructanase
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BIO-CAT, Inc.
Taste Sensitivity, Umami Taste Perception
Umami Taste Intensity and ad Libitum Meal Intake
Background Sweet and salty tastes can influence food intake {Sørensen, 2003 #40}. Increased intensity of these tastes has been shown to decrease food intake and increase satiation compared to the less intense taste, independent…
- Conditions
- Taste Sensitivity, Umami Taste Perception, Food Intake Regulation, Hedonic Function
- Trial name
- RiceSort (NCT07059117)
- Testing
- Hedonic mapping, Ad libitum risotto test meal
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Cow Milk Allergy
Diagnosis of Cow's Milk Protein Allergy Among Infants and Children in Assuit University Children Hospital
The study will assess the diagnosis of Cow's milk protein allergy (CMPA) among infant and children in Assiut University Children Hospital using skin prick test and specific serum IgE
- Trial name
- NCT03456479
- Testing
- skin prick test - specific serum IgE
- Volunteers
- 30 people
- Sponsor
- Assiut University
Healthy Volunteers, Atopic Diathesis and Atopic Dermatitis
Single Dose and Multiple Dose Study to Assess Safety and Tolerability of LOU064
This is a 6-part first-in-human study in up to approximately 184 participants. Parts 1 to 5 is in health volunteers and part 6 is in subjects with atopic dermatitis.
- Trial name
- NCT03918980
- Testing
- LOU064
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Cow Milk Allergy
Mineral Status Ininfants With Cow's Milk Protein Allergy
This study evaluate the mineral status of infants with cow's milk protein allergy which is affected due to the elimination of milk , and the change in this mineral status after receiving amino acid - based formula for 12 weeks.
- Trial name
- NCT04327297
- Testing
- Amino acid-based formula
- Volunteers
- 40 people
- Sponsor
- Assiut University
Allergy;Food, Allergy to Shrimp
Food Allergen OIT for Shrimp and Cashew
A prospective Phase 2, single-center, single-allergen OIT of cashew or shrimp in participants with proven allergies to either cashew or shrimp, respectively.
- Conditions
- Allergy;Food, Allergy to Shrimp, Allergy to Cashew Nut (Disorder)
- Trial name
- MOTIF (NCT03504774)
- Testing
- Cashew or Shrimp Oral Immunotherapy
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Sayantani B. Sindher
Milk Allergy
Xolair Treatment for Milk Allergic Children
This is a pilot feasibility study, using Xolair pretreatment for oral milk desensitization. The major assessment will be safety, and the investigators will evaluate for any type of reaction, including allergic reactions that…
- Trial name
- NCT00968110
- Testing
- omalizumab
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Boston Children's Hospital
Food Allergy, Anaphylaxis
Evaluation of the Sphingolipid Metabolite S1P as a Novel Biomarker in Food Allergy
Food allergies represent an increasing health concern in the industrialized countries and especially affect pediatric patients. In this population adverse reactions against food compounds can lead to anaphylactic reactions.
- Trial name
- NCT01776489
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Medical University of Vienna
Venous Thromboembolism, Atopic Dermatitis
The Incidence of Venous Thromboembolism in Atopic Dermatitis
This study aims to investigate the incidence of venous thromboembolism in people who are diagnosed with atopic dermatitis.
- Conditions
- Venous Thromboembolism, Atopic Dermatitis, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- NCT04969653
- Testing
- Exposure of venous thromboembolism
- Where
- United Kingdom
- Volunteers
- 754,745 people
- Sponsor
- Momentum Data
Atopic Dermatitis, Food Allergy
Development of Peanut, Sesame, and Tree Nut Allergy in Polish Children at High Risk of Food Allergy
The aim of the study is to assess the prevalence of peanut, tree nuts, and sesame allergy in Polish children at high risk of food allergy.
- Conditions
- Atopic Dermatitis, Food Allergy, Peanut Allergy, Tree Nut Allergy
- Trial name
- NCT05662800
- Testing
- Assessment of peanut, tree nuts and sesame allergy
- Where
- 2 sites in Poland
- Volunteers
- 240 people
- Sponsor
- Medical University of Warsaw
Cow Milk Allergy, Food Allergy
Detection of Metabolite Biomarkers for the Early Diagnosis and Prognosis of Cow's Milk Allergy in Children
In this study, fecal and urine samples will be collected from children diagnosed with : IgE mediated cow's milk allergy, suspected of a cow's milk allergy, but with negative diagnosis IgE mediated food allergy other than cow's…
- Trial name
- NCT04249973
- Testing
- Collection of urine and feces
- Where
- 8 sites in Belgium
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Ghent
Wheat Allergy, Anaphylaxis Food
Major Allergen in Wheat Anaphylaxis in Thai Population
To study Major allergen in Wheat anaphylaxis in Thai population To study and compare demographic data between group of wheat anaphylaxis
- Conditions
- Wheat Allergy, Anaphylaxis Food, Anaphylaxis Exercise
- Trial name
- NCT03487315
- Testing
- immunoblot
- Where
- Thailand
- Volunteers
- 36 people
- Sponsor
- Mahidol University
Peanut Allergy
Safety and Efficacy Study of Viaskin Peanut in Peanut-allergic Young Children 1-3 Years of Age
The study aims to assess the safety and efficacy of Viaskin Peanut to induce desensitization to peanut in peanut-allergic children 1 to 3 years of age after a 12-month treatment by EPicutaneous ImmunoTherapy (EPIT).
- Trial name
- EPITOPE (NCT03211247)
- Testing
- Part A Viaskin Peanut 250 mcg, Part A Viaskin Peanut 100 mcg, Part B Viaskin Peanut 250 mcg
- Where
- 51 sites in United States, Australia and 6 more
- Volunteers
- 414 people
- Sponsor
- DBV Technologies
Food Allergy
Improvement of Foodallergy Diagnostic in Gastrointestinal Tract
Currently, diagnostic possibilities for the detection of food allergy in the gastrointestinal tract are scarce. The endoscopic segmental Lavage is the method of choice, but it´s controversial.
- Trial name
- NCT03151252
- Testing
- Cytobrush
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Food Allergy
Induction of Sustained Unresponsiveness to Sesame Using High- and Low-dose Sesame Oral Immunotherapy
This is an experimental, interventional study, following on from a clinical trial comparing the efficacy and safety of oral immunotherapy with low and high doses of sesame protein, in which patient desensitisation was achieved…
- Trial name
- NCT05923216
- Testing
- High dose OIT, Low dose OIT
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Warsaw