Clinical trials: Hypertension, Ocular
Ocular Hypertension, Open Angle Glaucoma
CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension
To assess the safety, tolerability and efficacy of a single sustained release dose of OTX-TIC, a sustained release travoprost drug product, in subjects with primary open-angle glaucoma or ocular hypertension.
- Trial name
- NCT04360174
- Testing
- OTX-TIC
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- Ocular Therapeutix, Inc.
Glaucoma, Open-Angle, Glaucoma, Primary Open Angle
Following Patients After Selective and Pascal Laser Trabeculoplasty for Treatment of Chronic Open-Angle Glaucoma
The purpose of this study is to follow and describe the outcomes of patients after selective and pascal laser trabeculoplasty treatment for chronic open-angle glaucoma.
- Conditions
- Glaucoma, Open-Angle, Glaucoma, Primary Open Angle, Exfoliation Glaucoma, Glaucoma, Pigmentary
- Trial name
- FPSPLTTCOAG (NCT02679482)
- Where
- Colombia
- Volunteers
- 36 people
- Sponsor
- Fundación Oftalmológica Nacional
Glaucoma Medication Adherence, Glaucoma Patients
Eye Patient Adherence and Compliance Study
This study looks at ways to help people with glaucoma take their eye drops regularly and attend their clinic appointments. Each participant will be asked about the main challenges they face, such as forgetfulness, difficulty…
- Trial name
- EYE-PACIP (NCT07793474)
- Testing
- Eye Droppers, Eye Educate, Eye Coordinate
- Where
- Canada
- Volunteers
- 189 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Glaucoma
Polymorphisms in the Human Matrix Metalloproteinase Genes MMP1, MMP3, and MMP9: Genetic Risk Factors of Primary Open Angle Glaucoma?
Matrix metalloproteinases (MMPs) fulfill diverse important molecular functions and play pivotal roles in development, tissue morphogenesis, repair, aging, and inflammatory processes.
- Trial name
- NCT00312403
- Testing
- Blood Sample
- Where
- Austria
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Glaucoma, Ocular Hypertension
A Study to Evaluate the Effectiveness of Cosopt® as First Line Therapy (MK-0507A-153)
Evaluate the effectiveness of dorzolamide-timolol (Cosopt®) as first line therapy in reducing intraocular pressure in patients with untreated Open angle glaucoma (OAG) or Ocular hypertension (OH).
- Trial name
- NCT00546286
- Testing
- dorzolamide hydrochloride (+) timolol maleate, Comparator: dorzolamide HCl/timolol maleate + prostaglandin
- Volunteers
- 170 people
- Sponsor
- Merck Sharp & Dohme LLC
Glaucoma, Open-Angle
Use of Methazolamide to Lower Intraocular Pressure
The purpose of this study is to evaluate the effect of methazolamide, 25 mg or 50 mg tablets once a day for a week than twice a day for a week, on lowering intraocular pressure and the safety of methazolamide.
- Trial name
- NCT05498103
- Testing
- Methazolamide 25 MG, Methazolamide 50 MG
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Primary Open Angle Glaucoma, Secondary Open Angle Glaucoma
Early Diagnosis, Pathogenesis and Progression of Open Angle Glaucoma
The Erlangen Glaucoma Registry is a clinical registry for cross sectional and longitudinal observation of patients with open angle glaucoma (OAG) or glaucoma suspect, founded in 1991.
- Conditions
- Primary Open Angle Glaucoma, Secondary Open Angle Glaucoma, Ocular Hypertension
- Trial name
- NCT00494923
- Where
- Germany
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Glaucoma, Intraocular Pressure
Intraocular Pressure Fluctuation in Patients With Glaucoma and in Healthy Patients During Standard Yoga Positions
The purpose of the study is to investigate the IOP difference between normal and glaucomatous eyes using standard ophthalmic tonometry devices while subjects are performing different standard yoga asanas.
- Trial name
- NCT01915680
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Robert Ritch, MD, LLC.
Craniosynostosis, Strabismus
Ocular Characteristics in Patients With Craniosynostosis
Craniosynostosis are cranial deformations due to the premature closure of one or more cranial sutures. These deformations affect approximately one in 2.500 births.
- Conditions
- Craniosynostosis, Strabismus, Intracranial Hypertension, Amblyopia
- Trial name
- COPACA (NCT06928727)
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Glaucoma, Open-Angle, Ocular Hypertension
Direct Selective Laser Trabeculoplasty in Ethnic Chinese Population The Zhuiguang Trial
The objective of this study is to evaluate the effectiveness (Intra-Ocular Pressure lowering) and safety of Direct Selective Laser Trabeculoplasty (DSLT) in ethnic Chinese subjects with Primary Open Angle Glaucoma or Ocular…
- Trial name
- NCT05043831
- Testing
- DSLT
- Sponsor
- BelkinVision
Obstructive Sleep Apnoea, Open Angle Glaucoma
Prevalence of Obstructive Sleep Apnoea in Glaucoma
This study aims to investigate a potential link between Obstructive Sleep Apnoea (OSA) and Open Angle Glaucoma (OAG); initially by determining whether the prevalence of OSA is higher in patients with OAG in comparison to people…
- Trial name
- POSAG (NCT02713152)
- Where
- United Kingdom
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Papworth Hospital NHS Foundation Trust
Glaucoma
Evaluation of Visual Training System in Patients With Glaucoma
This study intends to conduct visual function examinations and follow-ups on two groups of glaucoma patients, one receiving visual perceptual training and the other serving as a control without training.
- Trial name
- NCT06433102
- Testing
- Visual perceptual training based on the lateral masking paradigm
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Glaucoma
Study on Micro-invasive Glaucoma Surgical (MIGS) Devices
Glaucoma is an ocular condition in which optic nerve damage occurs, frequently in the presence of increased pressure within the eye.
- Trial name
- NCT04092400
- Testing
- Micro-invasive Glaucoma Surgical Devices
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- National University Hospital, Singapore
Glaucoma
Baerveldt Plate Area Comparison (BPAC)
This research is being done to compare the safety and effectiveness of two sizes of the Baerveldt glaucoma implant. A Baerveldt glaucoma implant is one of the most common types of glaucoma operations performed.
- Trial name
- BPAC (NCT01159314)
- Testing
- Baerveldt Device surgical Procedure
- Where
- 5 sites in United States
- Volunteers
- 69 people
- Sponsor
- Johns Hopkins University
Glaucoma, Open-Angle
Internet-based, Naturalistic Evaluation of Tolerability and Individual Patient Target Pressures With Bimatoprost 0.03% in Glaucoma
The purpose of this study is to evaluate the range of target IOPs set for glaucoma patients starting monotherapy with bimatoprost and to evaluate patient and physician satisfaction with bimatoprost in "real-world" settings
- Trial name
- NCT00487214
- Volunteers
- 361 people
- Sponsor
- Allergan
Glaucoma
Comparison of Critical Flicker Fusion Versus Automated Visual Fields in the Detection of Early Glaucoma
The purpose of this study is to evaluate if critical flicker fusion is a more reliable method for detection of early glaucoma compared to automated visual fields in comparison to subjects without evidence of glaucoma or optic…
- Trial name
- NCT01076114
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Glaucoma, Glaucoma Open-Angle Primary
Analysis of Conjunctival Changes as Indicators for Ab-interno Gelatin Microstent Implantation Surgery Outcomes
Trabeculectomy and XEN45 gel stent implantation are glaucoma surgeries that creates an aqueous humor (AH) shunt towards the subconjunctival space (filtration bleb).
- Trial name
- IIT_XEN (NCT04727411)
- Testing
- XEN45 Gel stent, Trabeculectomy
- Where
- Spain
- Volunteers
- 39 people
- Sponsor
- Hospital Clinic of Barcelona
Glaucoma, Glaucoma, Open-Angle
Glaucoma Surgery Using the ViaLase Laser System
Prospective, single-center, multi-cohort clinical trial of ViaLase Laser for the reduction of IOP in patients with open angle glaucoma.
- Trial name
- NCT04949802
- Testing
- ViaLase Laser
- Where
- Hungary
- Volunteers
- 22 people
- Sponsor
- Vialase, Inc.
Diabetic Maculopathy, Age Related Macular Degeneration
Reading Analysis in Ophthalmologic Patients
Investigation of the reading parameters and fixation behavior in patients with different ocular diseases (age-related macular degeneration, glaucoma, diabetic maculopathy, epiretinal membrane) and healthy subjects.
- Conditions
- Diabetic Maculopathy, Age Related Macular Degeneration, Glaucoma, Epiretinal Membrane
- Trial name
- NCT03750149
- Testing
- EyeTracker
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Intraocular Pressure Disorder
The Effects of Virtual Colonoscopy on Intraocular Pressure
Our trial examined the intraocular pressure measurements differences, before and after virtual colonoscopy examination.
- Trial name
- NCT03090243
- Testing
- Virtual colonoscopy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shlomo gavrielli