Clinical trials: Hypertension, Pregnancy Induced
Pregnancy Induced Hypertension, Preeclampsia and Eclampsia
Role of L-citrulline in Prevention of Pregnancy Associated Hypertension
The target population for our study is healthy nulliparous pregnant women (first pregnancy) between the 12-16 week of pregnancy. If a subject is eligible, written consent will be obtained by person to person contact.
- Conditions
- Pregnancy Induced Hypertension, Preeclampsia and Eclampsia, Gestational Hypertension
- Trial name
- NCT04979793
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Restless Leg Syndrome, Severe Preeclampsia
Restless Leg Syndrome and Severe Preeclampsia
Restless Leg Syndrome is a common but not well recognized central nervous system disorder. It is more prevalent during pregnancy and, if present before pregnancy, can develop an exacerbation of symptoms.
- Trial name
- NCT01538147
- Where
- Panama
- Volunteers
- 310 people
- Sponsor
- Saint Thomas Hospital, Panama
Preeclampsia
Prediction of Adverse Perinatal Outcome for Preeclampsia in Sichuan Province of China
The purpose of this study is to build a model for the prediction of adverse perinatal outcome for preeclampsia in china
- Trial name
- NCT01804751
- Sponsor
- West China Second University Hospital
Pre-Eclampsia, Severe, Pregnancy
Finger Plethysmography to Predict Fluid Responsiveness in Healthy Pregnancy and Severe Preeclampsia
The goal of this observational study is to determine whether noninvasive finger plethysmographic cardiac output monitoring can help predict fluid responsiveness in pregnant women, including those with preeclampsia with severe…
- Trial name
- NCT07430254
- Testing
- Noninvasive finger plethysmographic cardiac output monitoring, Standard transthoracic echocardiographic assessment
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Stanford University
Induction of Labor
A Randomized Trial of Oral Misoprostol Alone Versus Oral Misoprostol Followed by Oxytocin for Labour Induction
The primary objective of the trial is to assess the following: In women who have undergone cervical preparation with oral misoprostol as part of labour induction for hypertensive disease in India, is augmentation using oral…
- Trial name
- MOLI (NCT03749902)
- Testing
- Oral misoprostol, Oxytocin
- Where
- 3 sites in India
- Volunteers
- 520 people
- Sponsor
- University of Liverpool
Patient Satisfaction
Patient Satisfaction With Abbreviated Postpartum Magnesium Sulfate for Severe Preeclampsia
Preeclampsia is a common and potentially devastating disease that affects only pregnant or postpartum patients. It is a leading cause of maternal mortality not only worldwide, but in the United States as well.
- Trial name
- NCT05789381
- Testing
- Magnesium sulfate
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Pregnancy Induced Hypertension
Prospects for the Prevention of Pregnancy-induced Hypertension and Preeclampsia Trial
Hypertensive disorders of pregnancy (HDP) are with 50.000 deaths every year one of the major causes of maternal mortality worldwide, especially in low and middle income countries.
- Trial name
- 4P (NCT02007837)
- Testing
- Combined aspirin and multinutrient supplement, Daily text reminder text messages
- Where
- 2 sites in Ghana
- Volunteers
- 440 people
- Sponsor
- UMC Utrecht
Cardiovascular Biomarkers, Preeclampsia (PE) Risk
A Study to Find and Confirm Blood-based Markers (Called Proteins) That May Show Early Heart Changes in Women With Preeclampsia, Even Before Symptoms Appear, and the Use of Heart Ultrasound (Echocardiography) to Look at Patterns of How the Heart Changes During Pregnancy in Women With Preeclampsia
The goal of this study is to find and confirm blood-based markers (called proteins) that may show early heart changes in women with preeclampsia, even before symptoms appear.
- Conditions
- Cardiovascular Biomarkers, Preeclampsia (PE) Risk, Preeclampsia (PE)
- Trial name
- PRECISE (NCT07463898)
- Testing
- No Intervention: Observational Cohort
- Where
- Nigeria
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Pregnancy, Prolonged, Pre Eclampsia
Foley Catheter Versus Vaginal Misoprostol for Cervical Ripening and Induction of Labor
PURPOSE: The purpose of this study is to determine the effectiveness of balloon dilatation (Foley) with vaginal misoprostol for cervical ripening and induction of labor.
- Conditions
- Pregnancy, Prolonged, Pre Eclampsia, Oligohydramnios
- Trial name
- NCT01140971
- Testing
- Misoprostol, Foley
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Municipal Hospital Vila Nova Cachoeirinha
Pre-eclampsia
Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia
OBJECTIVES: I. Determine the effectiveness of nimodipine versus magnesium sulfate in the prevention of eclamptic seizures in patients with severe preeclampsia.
- Trial name
- NCT00004399
- Testing
- magnesium sulfate, nimodipine
- Volunteers
- 2,000 people
- Sponsor
- FDA Office of Orphan Products Development
Preeclampsia
Second Trimester Maternal Serum Homocysteine Levels and Uterine Artery Doppler for Prediction of Preeclampsia and Placentation Disorders
The current study included the singleton pregnancies (without history of previous risk factors), had their homocysteine measured as part of a serum-screening program in addition to uterine artery Doppler.
- Trial name
- NCT02854501
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy Related
Women's Refusal to Participate in a Randomized Trial Involving First-trimester Screening for Pre-eclampsia: Factors Associated With Refusal and Reasons for Acceptance and Refusal
The main objective is to assess whether there are factors associated with women's refusal to participate in a randomized clinical trial involving first-trimester screening for pre-eclampsia.
- Trial name
- RANSPRE-refus (NCT06322771)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 472 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pre-Eclampsia, Hypertension, Pregnancy-Induced
Remifentanil for General Anesthesia in Preeclamptics
The purpose of this study is to determine whether remifentanil use in preeclamptic patients may blunt hemodynamic response to intubation during general anesthesia for cesarean section.
- Conditions
- Pre-Eclampsia, Hypertension, Pregnancy-Induced, Pregnancy Complications
- Trial name
- NCT00567957
- Testing
- Remifentanil, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Mild Pre-eclampsia, Severe Pre-eclampsia
Evaluation of Metabolic Acid-base Abnormalities in Pre-eclamptic Women Applying the Stewart-Fencl Approach
Acid/base imbalances are not well understood in pre-eclamptics, and better tools are needed to allow a thorough and meaningful evaluation.
- Trial name
- NCT02164370
- Where
- 2 sites in United States, South Africa
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Washington
Airway Assessment
Ultrasonographical Assessment of Airway Indices in Pregnancy
Clinical and ultrasound indices of airway, in addition to laryngoscopic view will be assessed and compared among three groups of patients: non pregnant, pregnant with normal blood pressure, preeclampsia patients undergoing…
- Trial name
- NCT07423741
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- South Valley University
Preeclampsia
Low Dose Aspirin for the Prevention of Preeclampsia
Preeclampsia is one of the three leading causes of maternal morbidity and mortality all over the world. The use of low dose aspirin has been mentioned in several studies with promising results.
- Trial name
- NCT01890005
- Testing
- Aspirin
- Where
- Panama
- Volunteers
- 476 people
- Sponsor
- Saint Thomas Hospital, Panama
Pre-Eclampsia
Preeclampsia Associated Vascular Aging
To evaluate cardiovascular health, especially endothelial health, of women after pre-eclampsia compared to women without pre-eclampsia, and to compare women who had taken PETN during pregnancy with women who had not attempted…
- Trial name
- PAVA (NCT04484766)
- Testing
- Primary data collection
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Jena University Hospital
Preeclampsia Postpartum
Aspirin and Preeclampsia
This is a single-center, double-blind, randomized, placebo-controlled clinical trial. Peripartum and postpartum Activin A are significantly elevated in women with preeclampsia.
- Trial name
- NCT04479072
- Testing
- Aspirin 81 mg
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Chicago
Preeclampsia
Daily Aspirin Treatment After Preeclampsia
Women who develop preeclampsia during pregnancy are four times more likely to develop cardiovascular disease later in life, even if they are otherwise healthy.
- Trial name
- NCT06168461
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Anna Stanhewicz, PhD
Preeclampsia
Antioxidant Supplementation in Pregnant Women With Low Antioxidant Status
The purpose of this study is to investigate antioxidants supplementation in pregnant women with low antioxidant status at 10-12 weeks gestation age in relation to adverse pregnancy outcome in randomized prospective study.
- Trial name
- NCT00388856
- Testing
- Vitamin C 1000mg and E 400IU
- Where
- Indonesia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Showa University
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