Clinical trials: Hypertension, Pregnancy Induced
Pre-Eclampsia
Can Atorvastatin Improve Vascular Function in Women With a History of Preeclampsia?
The purpose of the study is to test the hypothesis that a short course of atorvastatin can improve vascular function in women with a history of preeclampsia, compared to placebo.
- Trial name
- PVS3 (NCT01278459)
- Testing
- Atorvastatin
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- University of Oxford
Pre-Eclampsia
HMW-Adiponectin is Raised in Newborns
Cross sectional, hospital-based study dealing with adiponectin levels in newborns to mothers with pre-eclampsia. Venus cord blood samples were collected immediately after birth; 30 cases and 62 controls were enrolled into the…
- Trial name
- NCT00438542
- Sponsor
- University of Oslo
Preeclampsia
Aspirin for Prevention of Preeclampsia in Healthy, Nulliparous Obese and Overweight Pregnant Women
Preeclampsia is a pregnancy-specific syndrome that affects 3 - 5% of pregnancies. It is one of the main causes of maternal, fetal and neonatal morbidity and mortality, resulting in approximately 40,000 maternal deaths worldwide…
- Trial name
- NCT03725891
- Testing
- Aspirin 162 mg, Aspirin 81 mg
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Aswan University Hospital
Preeclampsia, Hypertension in Pregnancy
Bedside Monitoring to Identify Impaired Cerebral Autoregulation in Women with Postpartum Hypertension
The purpose of this research study is to develop a protocol for NIRS-based bedside monitoring to identify impaired cerebral autoregulation in women admitted to the high-risk obstetrics unit with postpartum hypertension.
- Trial name
- NCT05155852
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Columbia University
Pregnancy Complications, Preeclampsia
Severe Pregnancy Complications Are Associated With Elevated Factor VIII Plasma Activity
Congenital and acquired thrombophilia were identified as risk factors for thrombosis in systemic vessels.Thrombophilias have also been recently found to be associated with preeclampsia, intrauterine fetal growth restriction…
- Conditions
- Pregnancy Complications, Preeclampsia, Placental Abruption, Intrauterine Fetal Growth Restriction
- Trial name
- NCT00573118
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Preeclampsia
Predicting Late-onset Preeclampsia at 10-14 Weeks of Pregnancy
The aim of this study is to make it easier to predict late-onset preeclampsia at 11-14 weeks of pregnancy. This will be done by measuring certain proteins in the mother's blood together with obtaining the mother's medical…
- Trial name
- NCT04075708
- Where
- Denmark
- Volunteers
- 1,427 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Pregnancy, High Risk, Pre-Eclampsia
Blood Pressure Monitoring in High Risk Pregnancy to Improve the Detection and Monitoring of Hypertension
Raised blood pressure is a common problem in pregnancy. Raised blood pressure and pre-eclampsia affect about one in ten women and are a major cause of death and premature birth in the United Kingdom and worldwide.
- Conditions
- Pregnancy, High Risk, Pre-Eclampsia, Hypertension, Hypertension, Pregnancy-Induced
- Trial name
- BUMP (NCT03334149)
- Testing
- Self-Monitoring of Blood Pressure
- Where
- 13 sites in United Kingdom
- Volunteers
- 3,042 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Preterm Birth, Intra-uterine Growth Restriction
Consequences of Antiangiogenic Factors Involved in Preeclampsia on Intra-uterine Growth Restricted Preterm Newborn
Preeclampsia complicates about 2-7% of pregnancies and is a major contributor to maternal and neonatal morbidity and mortality worldwide.
- Conditions
- Preterm Birth, Intra-uterine Growth Restriction, Maternal Preeclampsia, Bronchopulmonary Dysplasia
- Trial name
- ANGIODYS (NCT01648855)
- Testing
- Biological samples
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension, Premature Birth
Trial of Exercise to Prevent HypeRtension in Young Adults
TEPHRA investigates the effect of exercise on blood pressure and other cardiovascular factors in young adults with different birth histories.
- Trial name
- TEPHRA (NCT02723552)
- Testing
- Aerobic Exercise
- Where
- United Kingdom
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Pre-Eclampsia
Midkine Role With Deregulated Oxidative and Immune Milieu in Induction of Preeclampsia
Preeclampsia (PE) is a hypertensive pregnancy-related disorder that endangers maternal and fetal outcomes and accounts for 9-10% of maternal mortalities with its early-onset phenotype is the most dangerous, but its etiology is…
- Trial name
- NCT06329284
- Testing
- ELISA
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Benha University
Preeclampsia
Treatment Approaches for Preeclampsia in Low-Resource Settings
Preeclampsia is a condition unique to pregnancy characterized by the new onset of hypertension and proteinuria. Eclampsia, characterized by maternal seizures, is a serious complication increasing the risk of maternal and infant…
- Trial name
- NCT00666133
- Testing
- SpringFusor Pump
- Where
- 2 sites in India
- Volunteers
- 304 people
- Sponsor
- Gynuity Health Projects
Hypertension in Pregnancy
Remote Surveillance of Postpartum Hypertension
Women with hypertensive disorders of pregnancy need postpartum blood pressure (BP) surveillance to detect persistent hypertension. Various barriers result in only 30% attendance at postpartum BP visits.
- Trial name
- TextBP (NCT03185455)
- Testing
- Remote (text based) surveillance
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- University of Pennsylvania
Preterm Birth, Intrauterine Growth Retardation
Fish Oil Trials in Pregnancy for the Prevention of Pregnancy Complications ('FOTIP')
The initial trial examined if fish oil supplementation during pregnancy could reduce the risk of pregnancy induced hypertension, intrauterine growth retardation, and preterm birth in pregnancies that were at increased risk of…
- Conditions
- Preterm Birth, Intrauterine Growth Retardation, Pregnancy Induced Hypertension
- Trial name
- FOTIP (NCT02229526)
- Testing
- Low dose fish oil, Low dose olive oil, High dose fish oil
- Volunteers
- 1,619 people
- Sponsor
- Sjurdur Frodi Olsen
Perinatal Death, Hypertension, Pregnancy-Induced
Pregnancy in the Context of Urbanicity and Climate Change. The Overall Aim of the Project is to Co-create, Implement, and Test New Clinical Guidelines in Order to Improve the Quality of Care in Antenatal Clinics in the Context of Urbanisation and Climate Change in Dar es Salaam, Tanzania.
Tanzania's population is growing quickly, and Dar es Salaam is one of the fastest-growing cities in the world. At the same time, the city is increasingly affected by very hot weather, flooding, and air pollution.
- Conditions
- Perinatal Death, Hypertension, Pregnancy-Induced, Abortion, Spontaneous, Stillbirth
- Trial name
- NCT07751432
- Testing
- CC-ANC intervention group.
- Where
- Tanzania
- Volunteers
- 1,060 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Preeclampsia, Small for Gestational Age at Delivery
Early Vascular Adjustments to Prevent Preeclampsia
Women destined to develop gestational hypertensive complications often exhibit deviant hemodynamic adaptation patterns before overt clinical disease.
- Conditions
- Preeclampsia, Small for Gestational Age at Delivery, HELLP Syndrome
- Trial name
- NCT04216706
- Testing
- tailored pharmaceutical treatment
- Where
- Netherlands
- Volunteers
- 314 people
- Sponsor
- Maastricht University Medical Center
Postpartum Period, Sepsis
Correlation of Survival in Puerperae by Electrical Impedance Tomography
Introduction: Electrical Impedance Tomography (TIE) consists of an equipment that enables the visualization / quantification in real time of the regional distribution of ventilation and pulmonary perfusion, as well as of…
- Conditions
- Postpartum Period, Sepsis, Respiratory Distress Syndrome,Adult, HELLP Syndrome
- Trial name
- COSIPBEIT (NCT03715647)
- Testing
- Sepsis, HELLP Syndrome, Respiratory Distress Syndrome Adult
- Volunteers
- 30 people
- Sponsor
- Amazon University
Thrombocytopenia, Small for Gestational Age (SGA)
Mechanism of Thrombocytopenia in Infants
This research project is studying the causes for low platelet levels in preterm infants. Platelets are a component of blood that helps with clotting.
- Conditions
- Thrombocytopenia, Small for Gestational Age (SGA), Preeclampsia
- Trial name
- NCT00333333
- Testing
- Cord blood
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Hypertension in Pregnancy, Preeclampsia
Blood Pressure Monitoring in Postpartum Women at Risk of Hypertension
Cardiovascular disease and hypertensive disorders of pregnancy (HDP) are the leading causes of maternal morbidity and mortality in the United States.
- Conditions
- Hypertension in Pregnancy, Preeclampsia, Gestational Hypertension, Chronic Hypertension With Pre-Eclampsia
- Trial name
- NCT05457504
- Testing
- Remote blood pressure monitoring, Usual Care
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Preeclampsia, Blood Pressure Check (Hypertension Screening)
EFFECT OF BLOOD PRESSURE MEASUREMENT IN DIFFERENT POSITIONS ON BLOOD PRESSURE VALUES AND ANXIETY LEVELS IN PREGNANT WOMEN WITH PREECLAMPSIA
Aim: This study examined the effects of blood pressure measurement in different positions on diastolic and systolic blood pressure values and anxiety levels in pregnant women diagnosed with preeclampsia.
- Trial name
- PREECLAMPSIA (NCT06898567)
- Testing
- Right Lateral Position, Left Lateral Position, Semi Fowler Position (45° Fowler)
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Istanbul University - Cerrahpasa
Mild Pre-eclampsia, Severe Preeclampsia
İs There a Relationship Between Severity of Preeclampsia and Maternal Heavy Metal Levels?
The purpose of this study, to investigate whether severity of preeclampsia is associated with altered levels of heavy metals (Cd, Hg, arsenic and Pb) in maternal blood, fetal blood, and maternal hair.
- Trial name
- NCT01906567
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital