Clinical trials: Hypertension, Pregnancy Induced
Pre-Eclampsia
DM199 for Pregnancy Complications
This entry was submitted in error by DiaMedica Therapeutics, Inc. and was not authorized by any of the trial Investigators or study sponsor (Stellenbosch University).
- Trial name
- NCT06875141
- Testing
- DM199
- Sponsor
- DiaMedica Therapeutics Inc
Preeclampsia
Optimizing the Use of Aspirin for the Prevention of Preeclampsia
Pregnant women at higher risk for preeclampsia (PE) are currently recommended to take low-dose aspirin (acetylsalicylic acid, ASA) daily from the first trimester until 36 weeks of gestation.
- Trial name
- Optim-PRE (NCT07665853)
- Testing
- Discontinuation of Acetylsalicilic acid 150 mg/day at 24-28 weeks of gestation
- Where
- 38 sites in Austria, Bulgaria and 5 more
- Volunteers
- 15,160 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Pregnancy, Infertility
Selenium Supplementation in Pregnancy
Serum levels of isolated anti-thyroperoxidase (TPOab) and anti-thyreoglobulin (Tgab) autoantibodies are strongly associated with an increased risk of miscarriage and premature deliveries in euthyroid pregnant women.
- Conditions
- Pregnancy, Infertility, Auto-immune Thyroiditis
- Trial name
- Serena (NCT01465867)
- Testing
- Selenium, Selenium + L-Thyroxine (LT4)
- Where
- 11 sites in Italy
- Volunteers
- 56 people
- Sponsor
- University of Roma La Sapienza
Gestational Hypertension, Cardiovascular Pregnancy Complication
Physical Activity and Cardiovascular Profile of Pre-conceptional Women At Risk for GHD
To compare the cardiovascular profile of pre-conceptional women at risk for developing Gestational Hypertensive Disorders in subsequent pregnancy before and after physical activity.
- Trial name
- SPORTY (NCT05888467)
- Testing
- supervised infrared exercise group, supervised non-infrared exercise group, Control group
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Kidney Injury, Proteinuria
Isosorbide Mononitrate For Anti-Vascular Endothelial Growth Factor (VEGF) Induced Kidney Injury
The purpose of this study is to test the hypothesis that isosorbide mononitrate prevents deterioration of renal function in patients receiving anti-angiogenic therapies that target vascular endothelial growth factor (VEGF).
- Conditions
- Kidney Injury, Proteinuria, Hypertension
- Trial name
- NCT04051957
- Testing
- Isosorbide Mononitrate
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The University of Texas Health Science Center, Houston
Hypertension in Pregnancy, Hypertension
Inorganic Nitrate Supplementation in Chronic Hypertensive Pregnancies
High blood pressure during pregnancy poses significant risks to both the mother and baby. A combination of factors, including advancing maternal age, rising obesity rates, and metabolic health issues, have amplified the…
- Conditions
- Hypertension in Pregnancy, Hypertension, Pregnancy
- Trial name
- NIT_CH (NCT06105775)
- Testing
- Inorganic Nitrate Capsule
- Where
- Brazil
- Volunteers
- 144 people
- Sponsor
- University of Sao Paulo
Gestational Hypertension
PREMOM-II: Pregnancy Remote Monitoring of Women with Gestational Hypertensive Disorders
The goal of this project is thoroughly evaluate the added value of telemonitoring (TM) program for women at risk for gestational hypertensive disorders (GHD), by investigating it impact on prenatal follow-up, health outcomes for…
- Trial name
- PREMOM-II (NCT04031430)
- Testing
- Telemonitoring, Longitudinal CV profiling during pregnancy and before and after the start/switch of antihypertensive medication, CV profiling before and after the start/switch of antihypertensive medication
- Where
- 5 sites in Belgium
- Volunteers
- 1,095 people
- Sponsor
- Hasselt University
Pregnancy, Miscarriage Less Than 12 Gestational Weeks
Low-Dose Aspirin in in Vitro Fertilization (IVF) and Intracytoplasmic Sperm Injection (ICSI) Treatments
In this study we hypothesized that low-dose aspirin therapy (100 mg daily) improves ovarian responsiveness, uterine haemodynamics and clinical pregnancy rates in unselected subjects undergoing IVF/ICSI when the treatment is…
- Conditions
- Pregnancy, Miscarriage Less Than 12 Gestational Weeks, Extrauterine Pregnancy, Preeclampsia
- Trial name
- NCT00683202
- Testing
- Acetylsalicylic acid
- Where
- Finland
- Volunteers
- 374 people
- Sponsor
- University of Oulu
Patients Hospitalized for Pre-eclampsia
Evaluation of Cardiovascular Risk After Preeclampsia in General Practitioners and Patients
Pre-eclampsia is a disease characterized by placental damage leading to a cascade of complications during pregnancy. It is initially manifested by high blood pressure and the presence of albumin in the urine.
- Trial name
- PreCarVasc (NCT06059937)
- Testing
- Patient with pre-eclampsia
- Where
- France
- Volunteers
- 155 people
- Sponsor
- Central Hospital, Nancy, France
Preeclampsia
The Effect of Epidural Anesthesia on the Optic Nerve Sheath Diameter in Preeclampsia
This study aims to assess the effect of epidural anesthesia on the optic nerve sheath diameter in parturients with preeclampsia.
- Trial name
- ONSD (NCT04095832)
- Testing
- Epidural anesthesia
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Seoul National University Hospital
Pregnancy Complications, Obesity
Acute Exercise Effects in Obese Pregnancy
Obesity before and during pregnancy is associated with a higher risk for a number of obstetric and metabolic complications in women and their offspring.
- Conditions
- Pregnancy Complications, Obesity, Pre-Eclampsia, Gestational Diabetes
- Trial name
- NCT03750695
- Testing
- Resistance exercise, Aerobic Exercise, Rest
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Gestational Hypertension, Preeclampsia (PE)
Postpartum CO Rehabilitation
Some women who develop high blood pressure during pregnancy, such as gestational hypertension or preeclampsia, may continue to have slightly or moderately high blood pressure after giving birth.
- Trial name
- NCT06920537
- Testing
- Postpartum Cardio-obstetric Rehabilitation Program
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Preeclampsia
Coenzyme Q10 Supplementation and Development of Preeclampsia
As preeclampsia is a disease specially affecting young and primiparous women, and due to the fact that we found previously in several studies a prevalence of 12%, to ensure a confidence of 95% and a power of 80%, it is necessary…
- Trial name
- NCT00300937
- Testing
- Coenzyme Q10
- Where
- Ecuador
- Volunteers
- 235 people
- Sponsor
- Teran, Enrique, MD, PhD
Preeclampsia
Marinobufagenin as a Target for DIGIBIND in Preeclampsia
Background: Preeclampsia is a combination of high blood pressure and other potentially life-threatening symptoms. Preeclampsia occurs in up to 10% of pregnancies and is a main cause of maternal and fetal death worldwide.
- Trial name
- NCT01328600
- Where
- 3 sites in Russia
- Volunteers
- 144 people
- Sponsor
- National Institute on Aging (NIA)
Preeclampsia
162 mg of Aspirin for Prevention of Preeclampsia
This is a study to assess if 162 mg of aspirin will decrease rates of preeclampsia in pregnant patients compared to 81 mg of aspirin.
- Trial name
- NCT05221164
- Testing
- Aspirin 162 mg
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Methodist Medical Center of Illinois
Preeclampsia
Biological Changes Associated With High Risk of Preeclampsia in Nulliparous Women
Primary outcome 1. to identify biological changes in nulliparous women at high risk for preeclampsia defined by combined screening by Fetal Medicine Foundation (FMF) 2.
- Trial name
- PRERISK (NCT06200571)
- Where
- 2 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Syncytiotrophoblast
From Cytotrophoblast to Syncytiotrophoblast
A deeper understanding of the syncytiotrophoblast development processes and its properties may allow a better understanding of the placenta pathological process for the development of treatment models for the relevant pregnancy…
- Trial name
- NCT02368821
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Pre-Eclampsia
Evaluation of HALP Score in Preeclampsia
Preeclampsia is a serious condition that can occur during pregnancy and can pose problems for both the mother and the baby. It occurs in approximately 2-8% of all pregnancies globally and is caused by issues with blood vessels…
- Trial name
- NCT05816044
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Pregnancy, Obesity
Advanced MRI for Uteroplacental Flow, Perfusion, Oxygenation & Inflammation
The purpose of the study is to develop advanced ultrasound (U/S) and Magnetic Resonance Imaging, known as MRI to study uteroplacental health.
- Conditions
- Pregnancy, Obesity, Preeclampsia
- Trial name
- NCT02791568
- Testing
- Ultrasound Scan, MRI Scan, Ferumoxytol
- Where
- 2 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Preeclampsia, Eclampsia
Vitamin D Supplementation Among Pregnant Women in Uganda for the Prevention of Hypertensive Disorders in Pregnancy, and Other Adverse Maternal and Foetal Outcomes
The goal of this randomised controlled trial is to investigate if vitamin D supplementation among pregnant women in Uganda prevents adverse maternal and foetal outcomes, with special emphasis on preeclampsia.
- Conditions
- Preeclampsia, Eclampsia, HELLP Syndrome
- Trial name
- MAMA (NCT07510568)
- Testing
- oral 2.000 IU vitamin D3 (cholecalciferol) daily, in addition to routine ANC supplementations
- Volunteers
- 1,980 people
- Sponsor
- St Mary's Hospital, Lacor
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