Clinical trials: Hypertension, Pregnancy Induced
Pre-Eclampsia, Pregnancy
Women Specific Cardiac Recovery After Preeclampsia
Pregnancy is considered a cardiovascular (CV) stress test, and complicated pregnancies are associated with an increased risk for cardiovascular disease (CVD) later in life.
- Conditions
- Pre-Eclampsia, Pregnancy, HELLP Syndrome, Intrauterine Growth Restriction
- Trial name
- WeCare (NCT02807324)
- Testing
- Venapunction
- Where
- Netherlands
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Fetal Demise, Fetal Growth Restriction
Dose Adjusting Enoxaparin Thromboprophylaxis Dosage According to Anti-factor Xa Plasma Levels Improve Pregnancy Outcome
The risk of venous thromboembolism increases in pregnancy. Thrombophilia whether genetic or acquired, is a hypercoagulable disorder that may increase the risk of venous thromboembolic events.
- Conditions
- Fetal Demise, Fetal Growth Restriction, Preeclampsia, Abruptio Placentae
- Trial name
- NCT01068795
- Testing
- enoxaparin
- Where
- Israel
- Volunteers
- 144 people
- Sponsor
- HaEmek Medical Center, Israel
Pre-Eclampsia
Prevention of Preeclampsia With Aspirin in Recipients of Donated Oocytes.
The main objective of this trial is to study the occurrence of preeclampsia in recipients of donated oocytes receiving aspirin at an early stage during pregnancy and to compare the results with those obtained in patients…
- Trial name
- PROVAS (NCT02174328)
- Testing
- Acetylsalicylic acid
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Pre-Eclampsia, Gestational Hypertension
Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide
Postpartum prophylactic HCTZ administration for prevention and relapse of preeclampsia or gestational hypertension.
- Conditions
- Pre-Eclampsia, Gestational Hypertension, Superimposed Pre-Eclampsia, Hypertension, Pregnancy-Induced
- Trial name
- NCT03298802
- Testing
- Hydrochlorothiazide 50mg Tablet
- Where
- 2 sites in United States
- Volunteers
- 453 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Pre-Eclampsia
Safety and Efficacy of Twelve Hours Duration of MgSO4 in the Treatment of Eclampsia in Low Resource Setting in Sudan
the investigators assume that magnesium sulphate for treating eclampsia can be safely reduced from 24 hours to shorter duration of therapeutic anticonvulsant effect for 12 hours.
- Trial name
- NCT03112551
- Testing
- Adminstration of magnesium Sulphate for treatment of eclampsia
- Where
- Sudan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gadarif University
Preeclampsia
Comparison of Intravenous Labetalol and Intravenous Hydralazine in Severe Preeclampsia
Due to limited data regarding preeclampsia from the local population, the debate is still ongoing in the study setting. Hence, the current study was planned to compare the efficacy of labetalol and hydralazine for the treatment…
- Trial name
- NCT07572656
- Testing
- Labetalol, Hydralazine
- Where
- Pakistan
- Volunteers
- 132 people
- Sponsor
- Muhammad Aamir Latif
Brain Health, Gestational Hypertension
Brain Health in Midlife
The purpose of this study is to learn if hypertensive disorders during pregnancy affects brain health in midlife.
- Conditions
- Brain Health, Gestational Hypertension, Alzheimer Disease, Dementia
- Trial name
- ADORE BRAIN (NCT06640842)
- Testing
- A combination of various tests and biomarkers will be completed to understand the effect of hypertensive disorders of pregnancy on brain health in midlife.
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Preeclampsia Severe, Preeclampsia Postpartum
Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of Preeclampsia
The objective of the study is to determine whether administration of vitamin C (1.5g/6 hours) in the first three days post-partum reduces the amount of extravascular lung water assessed by lung ultrasound in patients with severe…
- Trial name
- NCT03451266
- Testing
- Vitamin C
- Where
- Slovenia
- Volunteers
- 34 people
- Sponsor
- University Medical Centre Ljubljana
Pregnancy, Pre-eclampsia
LimPrOn: Limburg Pre-eclampsia Investigation
Background: Multiple adaptations at the cardiovascular system occurs during pregnancy. In the pregnancy condition pre-eclampsia (PE), this adaptations are abnormal.
- Trial name
- LimPrOn (NCT03509272)
- Testing
- remote monitoring
- Where
- 8 sites in Belgium
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Pre-Eclampsia, Vascular Diseases
Mechanisms of Pregnancy Vascular Adaptations
The investigators will collect omental tissue (research surgical excision) and placental tissue (standard of care clinical delivery) from both preeclamptic and non-preeclamptic women during their c-section and use these samples…
- Trial name
- NCT03806283
- Testing
- Omental Biopsy
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Preeclampsia
Determining the Risk Elevation After Maternity
Evaluating the long term cardiovascular risks of those mothers who have been diagnosed with preeclampsia in pregnancy.
- Trial name
- DREAM (NCT02305745)
- Testing
- Observational
- Where
- Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Preeclampsia, Gestational Hypertension
Serum Vasohibin, Cardiotrophin, Endocan & Perinatal Outcomes
Investigation of the relationship between maternal serum vasohibin-1, vasohibin-2, cardiotrophin -1 and endocan concentrations at the 11th and 14th weeks of gestation and adverse perinatal outcomes.
- Conditions
- Preeclampsia, Gestational Hypertension, Gestational Diabetes, Preterm Birth
- Trial name
- NCT06416995
- Testing
- first trimester serum diagnostic test
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Umraniye Education and Research Hospital
Preeclampsia
Study of Maternal and Fetal Cardiovascular Function in Hypertensive States of Pregnancy
The pharmacological treatment strategy is then tailored to the underlying hemodynamic phenotype of each patient. That is, rather than applying a one-size-fits-all treatment for all patients, therapy is tailored to the specific…
- Trial name
- CARDIAC-OAT (NCT06858345)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Preeclampsia
The Effect of Massage Ball Application on Blood Pressure, Fatigue and Anxiety in Pregnant With Preeclampsia
The aim of this study is to determine the effect of massage ball application on arterial blood pressure, fatigue and anxiety in pregnant women diagnosed with preeclampsia.
- Trial name
- NCT06066411
- Testing
- Massage Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Saglik Bilimleri Universitesi
Preeclampsia
ST- Depression on Electrocardiogram During Caesarean Section in Regional Anaesthesia in Women With Preeclampsia
The investigators examined whether there was a difference in the occurrence of ST depressions after injection of five or ten units of oxytocin, in preeclamptic patients delivered by caesarean section (CS) under regional…
- Trial name
- NCT01530230
- Testing
- oxytocin
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Uppsala University Hospital
Polycystic Ovary Syndrome
Metformin in Pregnant PCOS Women
To investigate the effect of metformin on pregnancy complications and pregnancy outcome in the II. and III. trimester of pregnancy in women with polycystic ovary syndrome.
- Trial name
- PregMet (NCT00159536)
- Testing
- Metformin
- Where
- 10 sites in Norway
- Volunteers
- 257 people
- Sponsor
- Norwegian University of Science and Technology
Preeclampsia Severe
Discontinuation of Magnesium Sulfate After Delivery in Women With Severe Preeclampsia. A Randomized Controlled Trial
All women with severe preeclmapsia were given a loading dose of 4 g magnesium sulfate IV followed by the maintenance dose of 1 g/h infusion till the delivery.
- Trial name
- NCT03318211
- Testing
- Magnesium Sulfate
- Volunteers
- 100 people
- Sponsor
- Cairo University
Preeclampsia
Magnesium and Vanadium Levels in Preeclampsia
Introduction: Vanadium important pollutants produced from anthropogenic activities, has been suggested to be embryotoxic and fetotoxic in a lot of studies.
- Trial name
- V-Mg&PrE (NCT04387565)
- Testing
- magnesium and vanadium measurements and compare
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Cengiz Gokcek Women's and Children's Hospital
Pre-Eclampsia, Fetal Growth Retardation
Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia
Placental insufficiency is the source of preeclampsia (PE) and intrauterine growth retardation (IUGR). Current data demonstrate a significant beneficial effect of prophylactic use of aspirin on the recurrence of placental…
- Conditions
- Pre-Eclampsia, Fetal Growth Retardation, Premature Birth, Placental Insufficiency
- Trial name
- NCT01352234
- Testing
- Acetylsalicylic Acid 160 mg, Acetylsalicylic Acid 80 mg
- Where
- Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Preeclampsia
Usefulness of Extracorporeal Removal of sFLT-1 in Women With Very Early Severe Preeclampsia
Introduction Preeclampsia is a multifactorial disease that is responsible of important adverse maternal and perinatal outcomes. Recently, it has been suggested that soluble fms-like tyrosine kinase 1, s-Flt1, induces…
- Trial name
- ADENA (NCT02286284)
- Testing
- Apheresis for extracorporal removal of sFlt-1
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.