Clinical trials: Hypertension, Renal, open to volunteers
Hypertension, Renal Insufficiency
Food Frequency Questionnaire to Assess Sodium Intake
EvalSel can precisely assess the salt intake of hospitalized patients in nephrology and cardiology or in medical consultation. It can determine salt consumption to the nearest gram.
- Trial name
- EVALSEL (NCT05533645)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Lille
Uncontrolled Hypertension
Netrod-Pilot Study of Renal Denervation With NetrodTM Sixelectrode Radiofrequency RDN System
This single-arm, non-randomized, open-label investigation aims to collect safety and efficacy data of the CE-Marked Netrod™ RDN System in treating European patients with primary hypertension in the absence of anti-hypertensive…
- Trial name
- NCT07061054
- Testing
- Netrod™ six-electrode radiofrequency renal denervation system
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Shanghai Golden Leaf MedTec Co. Ltd
Hypertension, Hypertension,Essential
Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR)
To obtain an assessment of the efficacy and safety of renal denervation by dehydrated alcohol injection, USP administered via the Peregrine System™ Infusion Catheter in hypertensive subjects in the absence of antihypertensive…
- Trial name
- RADAR (NCT07083765)
- Testing
- Dehydrated Alcohol Injection, USP
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Ablative Solutions, Inc.
Renal Artery Obstruction, Hypertension, Renovascular
A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension
A prospective Danish national registry of percutaneous transluminal renal angioplasty (PTRA) in high-risk patients with renal artery stenosis selected on the basis of common national criteria, and with a common follow-up protocol…
- Conditions
- Renal Artery Obstruction, Hypertension, Renovascular, Cardiovascular Diseases, Kidney Diseases
- Trial name
- DAN-PTRA (NCT02770066)
- Testing
- Percutaneous transluminal renal angioplasty
- Where
- 5 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- University of Aarhus
Cardiovascular Diseases, Cerebrovascular Disease
REnal Denervation After Stroke (REDs) Study - A Randomized Clinical Trial of Renal Denervation in the Subacute Phase of Stroke
The REnal Denervation after stroke (REDs) study is a national, multicenter, investigator-initiated randomized controlled clinical trial designed to assess the efficacy of catheter-based renal denervation (RDN) performed in the…
- Conditions
- Cardiovascular Diseases, Cerebrovascular Disease, Arterial Hypertension, Hypertension
- Trial name
- REDs (NCT07114757)
- Testing
- Renal denervation after stroke
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- Centro per la Lotta Contro l'Infarto - Fondazione Onlus
Hypertension, Resistant Hypertension
The Effect of Ablation Duration of Renal Denervation on Antihypertensive Efficacy
This is a prospective, multicenter, randomized controlled study designed to evaluate the effect of renal denervation (RDN) ablation duration on blood pressure reduction in patients with hypertension.
- Trial name
- RDN-DA (NCT07876479)
- Testing
- Renal Denervation Using a Multielectrode Radiofrequency Ablation Catheter (RDN016)
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Ruijin Hospital
Refractory Hypertension or Drug-intolerant Hypertension
Laparoscopic Adventitial Renal Denervation (RDN) for Refractory Hypertension
This is a first-in-human study to test the safety and effectiveness of a new device-based treatment for high blood pressure that is difficult to control with medicine. This condition is known as refractory hypertension.
- Trial name
- NCT07108829
- Testing
- Renal Artery Radiofrequency Ablation Clamp
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Chronic Kidney Diseases
miRNA in Chronic Kidney Diseases
Oxidative stress and endoplasmic reticulum (ER) stress play a key role in tubular damage in both acute kidney injury and chronic kidney disease (CKD).
- Trial name
- NCT06316284
- Where
- Croatia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Hypertension Arterial, Kidney Transplant
POTASSIUM-RICH SALT SUBSTITUTES IN KIDNEY TRANSPLANT RECIPIENTS
Excessive sodium intake and inadequate potassium intake in the diet are known risk factors for the development of arterial hypertension and an increased risk of cardiovascular events.
- Trial name
- NCT07178964
- Testing
- Potassium-enriched salt-substitute, Regular table salt
- Where
- Slovenia
- Volunteers
- 80 people
- Sponsor
- University Medical Centre Ljubljana
Hypertension (HTN), Diabetes (DM)
Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health (Healthy Heart - CKM)
The investigators are proposing a new team-based shared decision-making (SDM) program. The goal of this study is to see whether this program is practical and whether it may help adults with cardiometabolic risk factors and…
- Conditions
- Hypertension (HTN), Diabetes (DM), Hyperlipidaemia, Kidney Disease
- Trial name
- SDM in CKM (NCT07662616)
- Testing
- Team-based shared decision-making
- Volunteers
- 94 people
- Sponsor
- Johns Hopkins University
Conditions, Infections
Analysis of the Virtual Acute Care at Home Experience
The purpose of this study is to examine the implementation, intervention effectiveness, and dissemination of a digital acute care delivery model for improving selected health outcomes in the Hospital at Home population.
- Conditions
- Conditions, Infections, Heart Failure, Renal and Urinary Disorders
- Trial name
- HaH (NCT05952999)
- Testing
- Digital Care Solution as supportive personalized care, Traditional Hospital Level Care
- Where
- United States
- Volunteers
- 9,654 people
- Sponsor
- OSF Healthcare System
Chronic Kidney Diseases, Pregnancy
Kynurenine Concentrations During Pregnancy in Women With or Without Chronic Kidney Disease - A Prospective Multicenter Study
Chronic kidney disease (CKD) affects more than 10% of the population worldwide and represents the second most important risk factor for preeclampsia, a life-threatening complication of pregnancy responsible for approximately…
- Conditions
- Chronic Kidney Diseases, Pregnancy, Preeclampsia
- Trial name
- KIDNEY-MOM (NCT07411937)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 204 people
- Sponsor
- CHU de Reims
Cardiovascular Diseases, Chronic Kidney Diseases
Improving the Collaborative Health of Adult Dyads
This study tests the efficacy of a dyadic intervention to mitigate the adverse health consequences of adults with pre-existing chronic health conditions and their informal carepartners (IC).
- Conditions
- Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus, Type 2, Chronic Disease
- Trial name
- NCT05370014
- Testing
- Integrating Community-based Intervention Under Nurse Guidance with Families (iCINGS FAM)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Kidney Diseases, Food/Nutrition Insecurity
Supporting VETerans With Kidney Disease Through Food As Medicine
The goal of this pilot clinical trial is primarily learn if produce boxes improve clinical outcomes among Veterans with kidney disease and food or nutrition insecurity.
- Conditions
- Kidney Diseases, Food/Nutrition Insecurity, Diabetes, Hypertension
- Trial name
- VETFAM (NCT07194733)
- Testing
- VET FAM Product Box and Nutrition Education
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Eastern Colorado Health Care System
Hypertension, Renal Denervation Therapy
Efficacy and Safety of Renal Denervation on Isolated Diastolic Hypertension
This study aims to evaluate the efficacy and safety of renal denervation (RDN) in patients with isolated diastolic hypertension (IDH).
- Trial name
- NCT06783296
- Testing
- Renal Denervation, Renal Angiography
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Shanghai 10th People's Hospital
Chronic Kidney Disease, Hypertension (HTN)
Investigating Vascular Properties of HEMI and SPG Signals in Individuals With or at Risk for Chronic Kidney Disease
This prospective, single-center clinical investigation conducted in France will evaluate two non-invasive investigational devices (HEMI and SPG-NINOX) designed to assess microcirculation in adults.
- Conditions
- Chronic Kidney Disease, Hypertension (HTN), Type 2 Diabetes Mellitus (T2DM)
- Trial name
- STIMULUS-CKD (NCT07604922)
- Testing
- HEMI device, SPG-NINOX device
- Where
- France
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Arterial Hypertension
Fetuin A as a Predictor of Deterioration of Renal Function in Hypertonic Patients
Commonly used parameters (creatinine, estimated glomerular filtration rate, and urine albumin/creatinine ratio) for prediction of decline of renal function are sensitive for advanced kidney impairment.
- Trial name
- NCT05963126
- Testing
- No intervention.
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Ostrava
Coronary Artery Disease, Diabete Mellitus
Assessment and Management of Multiple Drug Use in Elderly Chronic Disease Patients
The purpose of this observational study is to understand the impact of polypharmacy on the prognosis of elderly patients with chronic diseases.
- Conditions
- Coronary Artery Disease, Diabete Mellitus, Chronic Kidney Disease, Hypertension
- Trial name
- NCT07180368
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Xijing Hospital
Acute Kidney Injury, Intra-Abdominal Hypertension
Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery.
- Trial name
- IAP-AKI (NCT07891026)
- Testing
- Serial Intra-Abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ugur Duman
Hypertension
Sitogilun Malate Plus Amlodipine in Patients With Hypertension and Risk of Early Kidney Damage
This is a multicenter, randomized, double-blind, parallel-controlled Phase IV clinical trial designed to evaluate the efficacy and safety of sitogilun malate tablets in combination with amlodipine besylate tablets in patients…
- Trial name
- SABER (NCT07876544)
- Testing
- Sitogilun Malate, Allisartan Isoproxil, Amlodipine besylate
- Where
- China
- Volunteers
- 456 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine