Clinical trials: Hypertension, Uncontrolled
Uncontrolled Diabetes, Uncontrolled Hypertension
Community Health Workers Reduce Social Barriers That Affect the Health of Patients With High Blood Pressure and Diabetes.
The goal of this mixed-methods study is to assess the impact of a Community Health Worker (CHW)-led social risk screening and referral in improving management of uncontrolled diabetes (DM) and hypertension (HTN) among patients…
- Trial name
- (CHW-SYSTIM) (NCT06926855)
- Testing
- CHC-level cluster randomized control trial
- Where
- 3 sites in United States
- Volunteers
- 72,726 people
- Sponsor
- Morehouse School of Medicine
Hypertension,Essential
An Observational Study to Evaluate Effectiveness and Safety of Amosartan Plus Tablet
This study was to evaluate the therapeutic effect and safety of Amosartan Plus tablet administration in uncontrolled essential hypertension patients.
- Trial name
- NCT05462535
- Testing
- Amosartan Plus Tab.
- Where
- South Korea
- Volunteers
- 4,785 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Contrast Induced Nephropathy
Preventing Contrast Nephropathy With Sodium Bicarbonate in Patients With Pulmonary Edema,Heart Failure,Uncontrolled HTN
Radio Contrast Induced Nephropathy (RCIN) remains a well recognized complication in patients undergoing diagnostic or interventional procedures requiring radiographic contrast agents.
- Trial name
- NCT00513825
- Testing
- Sodium Bicarbonate
- Where
- Iran
- Volunteers
- 72 people
- Sponsor
- Tehran University of Medical Sciences
Hypertension
The Efficacy and Safety of OROSARTAN® Versus CODIOVAN® in Patients With Essential Hypertension Uncontrolled With Monotherapy
A multi-center, randomized, double-blind, phase IV clinical trial to compare the efficacy and safety of OROSARTAN® tablet 5/160mg versus CODIOVAN® tablet 160/12.5mg in patients with essential hypertension uncontrolled with…
- Trial name
- NCT02433119
- Testing
- OROSARTAN® 5/160mg, CODIOVAN® 160/12.5mg
- Where
- South Korea
- Volunteers
- 238 people
- Sponsor
- Dong-A ST Co., Ltd.
Uncontrolled Hypertension
Engaging Patients in Adherence Interventions Using Behavioral Science
The overarching goal of the proposed research is to prepare an evidence-based clinical pharmacist-delivered medication adherence intervention for sustainable implementation and dissemination.
- Trial name
- ENGAGE-HTN (NCT06543394)
- Testing
- Primer postcard, Control recruitment letter, Behavioral theory-informed recruitment letter
- Where
- United States
- Volunteers
- 584 people
- Sponsor
- Columbia University
Hypertension
Effectiveness of Pharmaceutical Care on Primary Care Patients With Uncontrolled Hypertension
This randomized clinical trial is a multicentre study conducted at 4 community-based pharmacies within the Brazilian public health service, which freely distributes standardized medicines.
- Trial name
- EPHACA (NCT00807131)
- Testing
- Patient follow-up, Counseling, Drug dispensing
- Where
- Brazil
- Volunteers
- 301 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypertension; Community Health Workers
Effectiveness of a Community Health Worker Delivered Care Intervention for Hypertension Control in Uganda
Over 80% of the morbidity and mortality related to non-communicable diseases (NCDs) occurs in low-income and middle-income countries (LMICs).
- Trial name
- CHW-HTC (NCT05068505)
- Testing
- Community health worker delivered multicomponent intervention
- Where
- Uganda
- Volunteers
- 869 people
- Sponsor
- Charite University, Berlin, Germany
Hypertension
Effectiveness and Tolerability of Long-Acting Nifedipine Gastrointestinal Therapeutic System in Chronic Kidney Disease With Uncontrolled Hypertension Patients, a Prospective, Multicenter, Observational Study
Chronic kidney disease (CKD) and hypertension are two closely related common chronic diseases that have serious implications to human health.
- Trial name
- ADRENAL (NCT03194633)
- Testing
- Nifedipine controlled-release tablets(Nifedipine GITS, ADALAT, BAYA1040)
- Where
- China
- Volunteers
- 871 people
- Sponsor
- Bayer
Diabetes Mellitus, Hypertension
Phase 4 Study of the Efficacy of Losartan Based Therapy in Hypertensives With and Without Diabetes
To study antihypertensive efficacy of 12 weeks of Losartan based therapy Resilo (Losartan) and Resilo-H (Losartan+ Hydrochlorothiazide) in uncontrolled hypertensive and diabetic hypertensive patients.
- Trial name
- NCT03978884
- Testing
- Losartan 50Mg Tab, Losartan/Hydrochlorothiazide 50 Mg-12.5 Mg ORAL TABLET, Losartan/Hydrochlorothiazide 100 Mg-25 Mg ORAL TABLET
- Where
- Jamaica
- Sponsor
- The University of The West Indies
Arterial Hypertension, Medication Nonadherence
Feasibility of a Program on a Nurse-led Telephone 6-month-follow-up for Uncontrolled Hypertensive Women
This study evaluate the feasibility of a 6-month personalized support program for hypertensive and non-observant women, led by nurses by telephone follow-up.
- Trial name
- PreDynamiques (NCT03963934)
- Testing
- Program on a nurse-led telephone 6-month-follow-up for uncontrolled hypertensive women: a patient-tailored intervention
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Mme Edith DAUCHY
Hypertension
Improving Blood Pressure in Colorado
We will improve hypertension control in Colorado by implementing a population-based intervention using interactive voice response (IVR) technology that will be delivered to patients in three healthcare systems across Colorado…
- Trial name
- NCT00520988
- Testing
- Use of telephone-based Interactive Voice Recognition system
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- Kaiser Permanente
Hypertension, Renal Denervation
International First-in-Human Study of the EnligHTN Generation 2 System in Patients With Drug-resistant Uncontrolled Hypertension
The purpose of this First-in-Human Clinical investigation is to evaluate the safety and performance of the St. Jude Medical EnligHTN™ Generation 2 Renal Denervation System for the treatment of patients with drug-resistant…
- Trial name
- EnligHTN III (NCT01836146)
- Testing
- EnligHTN™ Renal Artery Ablation Catheter
- Where
- 6 sites in Australia, New Zealand
- Volunteers
- 39 people
- Sponsor
- Abbott Medical Devices
Treatment Adherence
Therapeutic Adherence in Uncontrolled Arterial Hypertension
In hypertension, highly prevalent, up to 10-15% of hypertensive patients have uncontrolled blood pressure despite being treated with ≥3 drugs, which is known as resistant hypertension.
- Trial name
- NCT04464746
- Testing
- implementation of a specific program to improve therapeutic adherence
- Where
- Spain
- Volunteers
- 47 people
- Sponsor
- Parc de Salut Mar
Hypertension
A Study to Investigate Efficacy and Safety of a TCA108 in Participants ≥18 Years With Uncontrolled Hypertension
The purpose of this study if to evaluate the efficacy and safety of TCA108 on treatment of hypertension.
- Trial name
- TRÍADE-HA (NCT07030101)
- Testing
- TCA108, Bramicar HCT, Micardis Anlo
- Volunteers
- 400 people
- Sponsor
- EMS
Essential Hypertension, Metabolic Cardiovascular Syndrome
Technological Innovation in the Virtual Assistance of Patients With Uncontrolled Arterial Hypertension - Hyper 2
The purpose of this study is to evaluate the effectiveness of the use of artificial intelligence in home monitoring in patients with uncontrolled arterial hypertension.
- Conditions
- Essential Hypertension, Metabolic Cardiovascular Syndrome, Heart Disease Risk Factors
- Trial name
- Hyper2 (NCT05843682)
- Testing
- Using the Avatr App
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo General Hospital
Hypertension, Physical Activity
Uncontrolled Hypertension Management Among Jordanian Adults
This study will evaluate a newly developed multimodal health intervention including dietary approach to stop hypertension (DASH) diet, exercise (Ex), and medication adherence (MA) using motivational interviewing (MI) counselling…
- Conditions
- Hypertension, Physical Activity, Dietary Habits, Medication Adherence
- Trial name
- DASH-ExMAMI (NCT06156631)
- Testing
- DASH-ExMAMI
- Where
- 4 sites in Jordan
- Volunteers
- 126 people
- Sponsor
- Universiti Sains Malaysia
ASCVD, Hyperlipidemia
Duke Cardiometabolic Prevention Clinic's Impact on High-risk Cardiovascular Patients With Uncontrolled Risk Factors
This project is studying whether a team-based specialty clinic can help people with type 2 diabetes and heart disease better manage their blood pressure and cholesterol.
- Conditions
- ASCVD, Hyperlipidemia, Hypertension
- Trial name
- DUKE PREVENT (NCT07117695)
- Testing
- Referral to the Duke Cardiometabolic Prevention Clinic
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Duke University
Hypertension
Safety and Efficacy Study of BMS-823778 to Treat Uncontrolled High Blood Pressure in Overweight and Obese Patients
The purpose of this study is to determine whether BMS-823778 is safe and effective in the treatment of hypertension in overweight and obese patients.
- Trial name
- NCT01602367
- Testing
- BMS-823778
- Where
- 35 sites in United States, Colombia and 3 more
- Volunteers
- 7 people
- Sponsor
- Bristol-Myers Squibb
Glaucoma, Intraocular Pressure
IOP Reduction After Anecortave Acetate Injection in Glaucoma Patients
Introduction: Ocular administration of glucocorticoids is a common and effective treatment for several ocular diseases. However it is often complicated with the elevation of intraocular pressure (IOP).
- Trial name
- NCT00533962
- Testing
- Anterior Juxtascleral Depot of Anecortave Acetate
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Hypertension
Monitoring Blood Pressure at Home
The overall goal of this project is to determine if measuring blood pressure at home and staying in contact with a team of pharmacists and physicians to manage your blood pressure is feasible.
- Trial name
- NCT06247111
- Testing
- Remote Blood Pressure Monitoring + Telehealth, Usual care
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Alabama at Birmingham