Clinical trials: Hypertension, suspended
Hypertension, COVID-19
Coronavirus (COVID-19) ACEi/ARB Investigation
Coronavirus disease 2019 (COVID-19) is a pandemic infection caused by a virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Trial name
- CORONACION (NCT04330300)
- Testing
- Thiazide or Thiazide-like diuretics, Calcium Channel Blockers, ACE inhibitor
- Where
- Ireland
- Volunteers
- 2,414 people
- Sponsor
- National University of Ireland, Galway, Ireland
Pulmonary Hypertension Associated With Interstitial Lung Disease
Efficacy and Safety of Seralutinib in Adult Subjects With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
This Phase 3 study is designed as a 24-week randomized, double-blind, placebo-controlled period (PCP) followed by a 144-week long-term extension (LTE) period.
- Trial name
- SERANATA (NCT07181382)
- Testing
- Seralutinib, Generic Dry Powder Inhaler
- Where
- 4 sites in United States, Israel
- Volunteers
- 480 people
- Sponsor
- GB002, Inc.
Methamphetamine Abuse, Pulmonary Hypertension
Screening of Pulmonary Hypertension in Methamphetamine Abusers
Methamphetamine is misuse if classified as a "likely" risk factor for pulmonary arterial hypertension (PAH). Nevertheless the actual prevalence of and a screening strategy for PAH in methamphetamine users have not been…
- Trial name
- SOPHMA (NCT04019600)
- Testing
- Echocardiography
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Preeclampsia, Pregnancy Induced Hypertension
Preeclampsia: A Marker for Future Cardiovascular Risk in Women
This study will compare blood vessel and hormone differences between women who have a history of a pregnancy complicated by preeclampsia or high blood pressure, and women who have a history of uncomplicated pregnancy in the last…
- Trial name
- NCT01519297
- Testing
- Irbesartan
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Glaucoma
Impact of an Educational Video on Satisfaction After Glaucoma Surgery
Overall Objective: This study will assess whether an educational video is effective in increasing patient satisfaction with glaucoma surgery. 1.
- Trial name
- NCT03958929
- Testing
- Educational Video
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Sun Yat-sen University
Parkinson Disease, Hypertension
Clinical Characteristics of Parkinson's Disease Subjects With Severe Hypertension During Motor OFFs.
Current management of hypertension in PD motor fluctuators is flawed. The current practice often is to treat transient hypertensive spikes reported by patients or measured in clinics with anti-hypertensive medications.
- Conditions
- Parkinson Disease, Hypertension, Antiparkinsonism Drugs Causing Adverse Effects in Therapeutic Use
- Trial name
- CLIN-HTN-PD (NCT03433950)
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Health and Science University
Hypertension
Comparison of Losartan Associated With Indapamide Versus Hyzaar® in the Hypertension Treatment
The purpose of this study is to evaluate the clinical efficacy of indapamide 1.5mg / losartan 50mg and indapamide 1.5mg / losartan 100mg on reduction of blood pressure.
- Trial name
- NCT01620788
- Testing
- Indapamide / Losartan, Hyzaar®
- Where
- Brazil
- Volunteers
- 636 people
- Sponsor
- EMS
Pre-Eclampsia
Evaluation of the Safety of Relaxin in Preeclampsia
The purpose of this study is to determine whether different doses of recombinant human relaxin is safe when given to women with severe preeclampsia
- Trial name
- NCT00333307
- Testing
- recombinant human relaxin
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Corthera, Inc.(formerly BAS Medical, Inc.), a member of the Novartis group of companies
Primary Open Angle Glaucoma
CRISPR/Cas9 Instantaneous Gene Editing Therapy to Intraocular Hypertensive POAG With MYOC Mutation
This study is intented to evaluate the safety, tolerability and preliminary efficacy of CRISPR/Cas9 Instantaneous Gene Editing Therapy (BD113 virus-like particle, also BD113vLVP) in patients with primary open-angle glaucoma…
- Trial name
- NCT06465537
- Testing
- BD113vVLP
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Shanghai BDgene Co., Ltd.
Proteinuria, Hypertension
Specific Blockage of Angiotensine 2 and Podocyturia in Glomerular Nephropathies With Hypertension and Proteinuria
Chronic glomerular diseases are one of the main causes leading to end stage renal disease (ESRD). Hypertension and proteinuria are two modifiable factors promoting the progression of ESRD.
- Conditions
- Proteinuria, Hypertension, End Stage Renal Disease
- Trial name
- NCT00369538
- Testing
- losartan, hydrochlorothiazide, hydrochlorothiazide, losartan
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Hypertension
The Chinese Mutation Hotspot of ENaC Causing Liddle's Syndrome and the Association of ENaC Variations and Hypertension
The variations of ENaC have an impact on the degradation of epithelial sodium channels and sodium reabsorption, and thus are associated with hypertension and hypokalemia.
- Trial name
- NCT00448162
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College
Glaucoma, Glaucoma, Open Angle
SOLX Gold Shunt Versus Control Implant: Randomized Trial for Refractory Glaucoma
Study Objective: To establish the substantial equivalence of the SOLX Gold Shunt to commercially available aqueous shunts, specifically the Ahmed™ Glaucoma Valve Model FP7, in the ability to reduce intraocular pressure (IOP)…
- Trial name
- NCT00382395
- Testing
- SOLX Gold Shunt GMS-plus, Ahmed FP7 Glaucoma Valve
- Where
- 15 sites in United States, Canada and 3 more
- Volunteers
- 180 people
- Sponsor
- SOLX, Inc.
Ocular Hypertension, Open Angle Glaucoma
Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertension
The aim of this research study is to assess the safety and feasibility of lowering intraocular pressure (IOP) using an experimental study drug, JV-GL1.
- Trial name
- NCT04761705
- Testing
- JV-GL1, Latanoprost 0.005% Ophthalmic Solution
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- JeniVision, Inc.
Hypertension
Telehealth Referral to Improve Outcomes
Emergency patients often have uncontrolled asymptomatic hypertension upon discharge from the emergency department. This 3-arm randomized controlled trial will evaluate the impact of nurse telehealth encounters and remote patient…
- Trial name
- TRIO (NCT05000970)
- Testing
- blood pressure cuff PLUS tablet, Telehealth Consult
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypertension, Blood Pressure
A Prospective Study on The"Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting"
In recent years, with the investment from government in the health management of the elderly, community management of hypertension in the elderly has made great progress in management rate and standardized management, but the…
- Trial name
- PROMISE (NCT04135911)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Yan Li
Cervical Cancer, Breast Cancer
Guangzhou Women's Health Cohort Study (GWHCS)
The Guangzhou Women's Health Cohort Study aims to explore the health trajectory and factors contributing to the health of women aged 35-64 in Guangzhou.
- Conditions
- Cervical Cancer, Breast Cancer, Lung Cancer, Colorectal Cancer
- Trial name
- NCT05506800
- Where
- China
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Hypertension
Autonomic Nervous System Function - Hypertension
The Life University Center for Chiropractic Research is conducting a research study to better understand the physiological differences, in terms of Autonomic nervous system function, between individuals with Hypertension and…
- Trial name
- NCT05312996
- Testing
- Heart Rate Variability, Galvanic Skin Response (Biopac)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Life University
High Risk Pregnancy
Efficacy of Aspirin and L-arginine in High Risk Preeclamptic
Worldwide, the incidence of preeclampsia ranges from 2 to 10% of pregnancies. The World Health Organization (WHO) estimates that the incidence of preeclampsia is seven times higher in developing countries than in developed (2.8%…
- Trial name
- NCT02838030
- Testing
- L-arginine, acetylsalicylic acid
- Where
- Mexico
- Volunteers
- 82 people
- Sponsor
- University of Guadalajara
Heart Failure, Pulmonary Hypertension
Exercise Training to Improve Cardiopulmonary Hemodynamics in Heart Failure Patients
This research study is being done to find out if exercise therapy can help improve the heart function, overall health, and quality of life of patients with pulmonary hypertension caused by heart failure.
- Trial name
- NCT04909008
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Cardiac Surgery, Hypertension, Pulmonary
The Effect of Pituitrin on the Patients With Pulmonary Hypertension Undergoing Cardiac Surgery
This study is a parallel group, single blind, randomized controlled trial. Patients with pulmonary hypertension who met the inclusion criteria and planned to undergo elective cardiac surgery under cardiopulmonary bypass from July…
- Trial name
- NCT05727618
- Testing
- Pituitrin, normal saline
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Qianfoshan Hospital