Clinical trials: Hypertension (HTN), open to volunteers
Hypertension (HTN), CKD - Chronic Kidney Disease
Community Health Worker Nutrition Self-Management Support for Cardio-Kidney-Metabolic Health
This study tests whether adding CHW support to usual nutrition care helps adults with type 2 diabetes, hypertension, or chronic kidney disease manage their diet and health.
- Conditions
- Hypertension (HTN), CKD - Chronic Kidney Disease, Cardio-Renal Syndrome, Food Insecurity
- Trial name
- INTEGRATE-CHW (NCT07918508)
- Testing
- INTEGRATE-CHW, Usual Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Florida International University
Hypertension (HTN), Healthy Adult Participants
Study of AB-110 in Healthy and Hypertensive Participants
This Phase 1, randomized, double-blind study is designed to evaluate safety, tolerability, PK, and PD effects of AB-110. This study will be conducted in 2 parts: a single ascending dose (SAD; Part A) in healthy participants with…
- Trial name
- NCT07916961
- Testing
- Active drug
- Where
- New Zealand
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Antlia Bioscience, Inc
Hypertension, Hypertension (HTN)
Common Carotid Artery-Renal Artery-Femoral Artery Survey for Hypertension
To evaluate both sides of the common carotid artery, renal artery, and femoral artery in Hypertension patient that cause of systemic arterial hypertension and/or the effects of target organ damage, both structural and functional…
- Conditions
- Hypertension, Hypertension (HTN), Artery Disease, Target Organ Damage
- Trial name
- CRF Survey (NCT07760623)
- Testing
- Diameter measurement, Velocity
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- DejthidaNathaphong
Hypertension (HTN), Blood Pressure
Team-Based Shared Decision-Making Program in Hypertension Control (Healthy Heart - BP Program)
The main goal of the study is to conduct a pilot trial to test the feasibility of the Team-Based Shared Decision-Making (SDM) Program, supported by Healthy Heart, involving 90 adults with uncontrolled hypertension (HTN) at…
- Trial name
- SDM in BP (NCT07909161)
- Testing
- Pharmacist-led Team-Based SDM on health behavior change and medication management for HTN control, Nurse-led Team-Based SDM on health behavior change and medication management for HTN control, Telehealth SDM visits focus on medication management and health behavior change
- Volunteers
- 90 people
- Sponsor
- Johns Hopkins University
End Stage Kidney Disease (ESKD), Hypertension (HTN)
Guiding Optimal Blood Pressure Management in Peritoneal Dialysis Pilot Trial
The GOAL-BP pilot study will help determine whether a study comparing two blood pressure goals can be carried out in adults with end-stage kidney disease and high blood pressure who receive peritoneal dialysis.
- Conditions
- End Stage Kidney Disease (ESKD), Hypertension (HTN), Peritoneal Dialysis (PD)
- Trial name
- GOAL-BP (NCT07910773)
- Testing
- Target systolic blood pressure <120 mmHg., Target systolic blood pressure <140 mmHg
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Hypertension (HTN), Hypertension
A Study to Evaluate the Effectiveness and Safety of S-amlodipine-based Monotherapy and Combination Therapy
This study aims to evaluate the effectiveness, safety, and clinical utility as a treatment strategy of the s-amlodipine-based monotherapy, dual combination, and triple combination in patients with hypertension across various…
- Conditions
- Hypertension (HTN), Hypertension, Essential (Primary) Hypertension
- Trial name
- STRIKE (NCT07907822)
- Volunteers
- 4,528 people
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
Hypertension (HTN), Diabetes (DM)
Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health (Healthy Heart - CKM)
The investigators are proposing a new team-based shared decision-making (SDM) program. The goal of this study is to see whether this program is practical and whether it may help adults with cardiometabolic risk factors and…
- Conditions
- Hypertension (HTN), Diabetes (DM), Hyperlipidaemia, Kidney Disease
- Trial name
- SDM in CKM (NCT07662616)
- Testing
- Team-based shared decision-making
- Volunteers
- 94 people
- Sponsor
- Johns Hopkins University
Hypertension (HTN), Diabetes
Evaluation of a New Virtual Care Pathway for Older Adults With Noncommunicable Diseases
The purpose of this study is to evaluate a newly developed virtual care program for older adults with chronic diseases (hypertension, diabetes and lipid disorders) whether it is feasible and economical to implement in the…
- Conditions
- Hypertension (HTN), Diabetes, Dyslipidaemia
- Trial name
- TeleCOOP-NCD (NCT07843238)
- Testing
- Teleconsultation care pathway for older adults with NCDs (TeleCOOP-NCD©)
- Where
- Malaysia
- Volunteers
- 160 people
- Sponsor
- National University of Malaysia
Hypertension (HTN)
Hypertension Treatment in Nigeria 2.0
The purpose of the second phase of the Hypertension Treatment in Nigeria (HTN 2.0) Program is to build upon the success of the first phase of the HTN Program (2020-2023), which implemented the WHO HEARTS package across 60 primary…
- Trial name
- HTN 2 (NCT07351162)
- Testing
- Implementation of a modified WHO HEARTS Hypertension Treatment Bundle
- Where
- 49 sites in Nigeria
- Volunteers
- 10,000 people
- Sponsor
- Washington University School of Medicine
Hypertension, Hypertension (HTN)
Clinical Decision Support Tool for the Treatment of Uncontrolled Hypertension
The goal of this clinical trial is to study whether having a clinical decision support (CDS) tool available to clinician use will more effectively lower BP 4 weeks after an outpatient visit compared with usual care.
- Conditions
- Hypertension, Hypertension (HTN), Blood Pressure, High, Blood Pressure Control
- Trial name
- AI-HTN (NCT07218198)
- Testing
- Standard medical treatment, Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- The Cleveland Clinic
Hypertension (HTN)
Spinal Cord Stimulation for Blood Pressure Control in Hypertension
High blood pressure, also called hypertension, raises the risk of heart disease, stroke, and kidney disease. Medications work well for many people, but some people still have blood pressure that stays too high, or they have side…
- Trial name
- HTN-SCS (NCT07842315)
- Testing
- Lower Thoracic Spinal Cord Stimulation
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Calgary
Cardiovascular Diseases, Chronic Kidney Diseases
Improving the Collaborative Health of Adult Dyads
This study tests the efficacy of a dyadic intervention to mitigate the adverse health consequences of adults with pre-existing chronic health conditions and their informal carepartners (IC).
- Conditions
- Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus, Type 2, Chronic Disease
- Trial name
- NCT05370014
- Testing
- Integrating Community-based Intervention Under Nurse Guidance with Families (iCINGS FAM)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Hypertension (HTN), Hypertension ,Pregnancy
REmote Physical ACtivity Intervention for High Blood Pressure Postpartum
The purpose of this intervention is to help new mothers who had elevated blood pressure during pregnancy become more physically active after birth. The investigators will connect data from FitBits to the electronic health record.
- Conditions
- Hypertension (HTN), Hypertension ,Pregnancy, Physical Activity
- Trial name
- REACH BP (NCT07127731)
- Testing
- Patient Portal Messaging, FitBit EHR Linkage
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Hypertension (HTN)
Project HOPE (Hypertension Outreach Through Partnership and Engagement)
The goal of this study is to learn if a nurse-led, task-shifting, community-based program can help lower blood pressure in adults aged 25 and older with uncontrolled high blood pressure (hypertension) in Monrovia, Liberia.
- Trial name
- HOPE (NCT07681726)
- Testing
- Project HOPE Intervention
- Where
- Liberia
- Volunteers
- 150 people
- Sponsor
- Johns Hopkins University
Hypertension (HTN), Vascular Diseases
The BASIC-S Feasibility Study for Vascular Risk Reduction
Vascular risk factors drive stroke, heart disease, and dementia, but translating lifestyle guidelines into routine clinical care remains challenging.
- Conditions
- Hypertension (HTN), Vascular Diseases, Stroke, Dementia
- Trial name
- BASIC-S (NCT07755631)
- Testing
- BASIC-S Intervention, Standard / Usual Care
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Andrew Appleton
Cardiovascular Disease (CVD), Heart Failure
Study of the Progression of Chronic Cardiovascular Conditions
This study will collect physiologic data in patients with cardiovascular conditions and observe the natural history of those conditions for research purposes.
- Conditions
- Cardiovascular Disease (CVD), Heart Failure, Aortic Stenosis, Aortic Stenosis Disease
- Trial name
- OCORO (NCT07420907)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Prolaio
Hypertension (HTN)
Assessing the Feasibility of the "Heart Care Pairs" Intervention
The researchers will invite 30 patients in primary care who have high blood pressure to participate in this health program with a supportive partner of their choosing (these will be the "participant pairs").
- Trial name
- NCT07760350
- Testing
- Dyadic lifestyle intervention for CVD risk reduction
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Alabama at Birmingham
Hypertension (HTN), Food Insecurity
Navigating Hypertension and Food Insecurity
This multi-site randomized controlled trial uses a community-based approach to evaluate a Food as Medicine program for Native Hawaiian and Pacific Islander (NHPI) adults in Hawaii who have high blood pressure and difficulty…
- Trial name
- NCT07544836
- Testing
- Produce Prescription Only, Community Health Worker navigated Produce Prescription
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Hawaii
Hypertension (HTN)
Feasibility and Acceptability of Isometric Exercise and Lifestyle Change for the Management of Hypertension
High blood pressure (hypertension) is a leading risk factor for cardiovascular diseases and may contribute to poor health and premature death.
- Trial name
- NCT07213479
- Testing
- Isometric Exercise and Lifestyle Change Advice, Lifestyle Change Advice
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Northumbria University
Chronic Kidney Disease, Hypertension (HTN)
Investigating Vascular Properties of HEMI and SPG Signals in Individuals With or at Risk for Chronic Kidney Disease
This prospective, single-center clinical investigation conducted in France will evaluate two non-invasive investigational devices (HEMI and SPG-NINOX) designed to assess microcirculation in adults.
- Conditions
- Chronic Kidney Disease, Hypertension (HTN), Type 2 Diabetes Mellitus (T2DM)
- Trial name
- STIMULUS-CKD (NCT07604922)
- Testing
- HEMI device, SPG-NINOX device
- Where
- France
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France