Clinical trials: Hypertensive Disorders
Hypertension
Program for Health Promotion to Improve Therapeutic Compliance in Hypertensive Patiente
The aim was to test if interpersonal relationships group strategies provided by nursing can promote an additional benefit on blood pressure (BP) control and quality of life (QoL) in hypertensive patients.
- Trial name
- PHPTCHP (NCT02036814)
- Testing
- Program Health Education
- Volunteers
- 21 people
- Sponsor
- University of Sao Paulo General Hospital
Hypertension, Chronic Kidney Disease
Effects of Aliskiren in Elderly Hypertensive Chronic Kidney Disease (CKD) Patients
The purpose of this study is to determine whether aliskiren is effective in the treatment of blood pressure, hear function, renal function in elderly hypertensive chronic kidney disease (CKD) patients.
- Trial name
- NCT01284114
- Testing
- Aliskiren
- Where
- 4 sites in Japan
- Volunteers
- 23 people
- Sponsor
- Jichi Medical University
Hypertension
SHINE: Trends and Satisfaction in Hypertensives Using Aktiia Optical BP Monitoring Device (SHINE)
The SHINE study aims to gather data on the evolution of participant's blood pressure and to correlate this with demographic, lifestyle and health factors in a hypertensive population as well as, to gather data on participants'…
- Trial name
- SHINE (NCT06356077)
- Where
- United Kingdom
- Volunteers
- 1,729 people
- Sponsor
- Aktiia SA
Hypertension, Sleep Apnea
Losartan in Hypertensive Men and Women With Sleep Apnea Before and on Continuous Positive Airway Pressure (CPAP) Treatment
Obstructive sleep apnea (OSA) is a highly prevalent condition in hypertensive patients. The renin-angiotension-aldosterone-system (RAAS) has a central role in blood pressure control.
- Trial name
- LosartanPAP (NCT00701428)
- Testing
- Losartan, CPAP
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Skaraborg Hospital
Hypertension
Clinical Characteristics and Medication Satisfaction of Kanarb Tablet in Korean Hypertensive Patient(Kanarb-Hypertension Epidemiology Medication Satisfaction Study)
1. Investigate the clinical characteristics, medication satisfaction and quality of life of anti-hypertensive drugs in Korean hypertensive patients 2.
- Trial name
- K-HEMS (NCT02394392)
- Where
- South Korea
- Volunteers
- 12,691 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Diabetes Mellitus, Hypertension
Correlation of Albuminuria With Arterial Stiffness
The investigators aim to investigate the relationship between albuminuria and arterial stiffness in diabetic patients, hypertensive patients and healthy subjects.
- Conditions
- Diabetes Mellitus, Hypertension, Albuminuria, Vascular Stiffness
- Trial name
- NCT01041599
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Hypertension
The Impact of Mobile Application-Supported Monitoring on Treatment Compliance and Success in Lifestyle Changes in Hypertensive Patients
Hypertension (HT) is defined as an arterial blood pressure persistently exceeding 140/90 mmHg in repeated measurements. It is a systemic disease characterized by chronically elevated blood pressure, which can lead to severe…
- Trial name
- NCT07299266
- Testing
- Mobile App-Supported Blood Pressure Monitoring
- Volunteers
- 40 people
- Sponsor
- University of Gaziantep
Hypertension, Resistant Hypertension
Effects of Aerobic Exercise on Blood Pressure Levels of Resistant Hypertensive Subjects
The aim of this intervention study is to evaluate the acute and chronic effects of different intensity (mild, moderate and high intensity) of aerobic exercise on blood pressure levels of subjects classified as resistant…
- Trial name
- NCT02670681
- Testing
- Aerobic Exercise Training
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of Paraíba
Cardiac Fibrosis, Diastolic Dysfunction
Effects of Pycnogenol on Cardiac Fibrosis and Diastolic Dysfunction in Aged Hypertensive Subjects
The purpose of this study is to determine whether Pycnogenol, a natural pine bark extract, is effective in modifying the age-dependent process of cardiac fibrosis and diastolic function in aged hypertensive subjects.
- Trial name
- NCT00952627
- Testing
- Pycnogenol
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Arizona
Hypertension
Efficacy and Safety of LCZ696 Compared to Olmesartan in Essential Hypertensive Patients Not Responsive to Olmesartan
This study will assess the efficacy and safety of LCZ696 in comparison to olmesartan in essential hypertensive patients not adequately responsive to olmesartan
- Trial name
- NCT01876368
- Testing
- LCZ696, Olmesartan
- Where
- 51 sites in United States, Argentina and 5 more
- Volunteers
- 376 people
- Sponsor
- Novartis Pharmaceuticals
Cardiovascular Diseases, Hypertension
Vascular Dysfunction in Hypertensive Postmenopausal Women
The purpose of this study is to investigate the role of ET-1 in mediating vasoconstrictor tone in hypertensive postmenopausal women (PMW) alone and in combination with a commonly prescribed Angiotensin II (ANG II) antagonist.
- Trial name
- NCT03371823
- Testing
- Normotensive, Hypertensives
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Hypertension Arterial
Antihypertensive Effects of Rosmarinus Officinalis L. Infusion
This study assessed the antihypertensive effect of rosemary tea through a placebo-controlled clinical study, angiotensin-converting enzyme (ACE) inhibition analysis, and in silico evaluation of interactions between rosemary…
- Trial name
- NCT07386210
- Testing
- Rosemary extract infusion
- Where
- 2 sites in Tunisia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- awatef Sassi
Hypertension
Valsartan/Hydrochlorothiazide Combination in Hypertensive Patients Not Controlled With Valsartan Alone
This study will test the effectiveness and safety of a combination treatment in patients whose blood pressure is not controlled with a single medication.
- Trial name
- NCT00170989
- Testing
- valsartan plus hydrochlorothiazide
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 2,714 people
- Sponsor
- Novartis
Ocular Hypertension
Safety and Efficacy of Liposomal Latanoprost in Ocular Hypertension
Aim: Evaluation of a single subconjunctival injection of liposomal EggPC formulation of latanoprost in treating glaucoma. Hypothesis: The investigators have already evaluated carrier stability, drug partitioning, in vitro drug…
- Trial name
- NCT01987323
- Testing
- Subconjunctival injection of liposomal latanoprost
- Volunteers
- 6 people
- Sponsor
- Singapore Eye Research Institute
Lifestyle Intervention, Lifestyle Modification
Effect of Counselling Using Lifestyle Medicine Assessment Tool on Hypertensive Patients
The goal of this clinical trial is to learn if knowing and understanding a patient's daily habits and then giving clear advice on what changes to make can help control blood pressure better than the routine way of advising people…
- Conditions
- Lifestyle Intervention, Lifestyle Modification, Hypertension, Counselling
- Trial name
- NCT07449962
- Testing
- Lifestyle Intervention
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Indus Hospital and Health Network
Arterial Hypertension, Metabolic Syndrome
Blood Pressure Control and Compliance to Treatment in Hypertensive Patients With Metabolic Syndrome: a Study Based on Home Blood Pressure Telemonitoring and Assessment of Psychological Determinants
The purpose of this study is to assess whether, in patients at high cardiovascular risk (hypertension with metabolic syndrome), long-term (1-year) blood pressure control is most effective when based on home blood pressure…
- Trial name
- TELEBPMET (NCT01541566)
- Where
- 12 sites in Italy
- Volunteers
- 254 people
- Sponsor
- Italian Institute of Telemedicine
Covid19, Hypertension
Inspiratory Muscle Trainer and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) COVID-19 Persistent Symptoms
Inspiratory muscle training considered as safe and valid method to improve respiratory muscle strength and functional capacity among uncountable conditions which could improve post COVID-19 persistent symptoms including but not…
- Conditions
- Covid19, Hypertension, Corona Persistent Symptoms
- Trial name
- NCT04919031
- Testing
- Inspiratory muscle trainer, diaphragmatic release
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Hypertension, Cardiovascular Disease
Combination of OLMesartan and CCB or Low Dose Diuretics in High Risk Elderly Hypertensive Patients Study (COLM-Study)
The purpose of this study is to investigate which combination therapy is more effective in reducing the incidence of cardiovascular events in Japanese elderly high-risk hypertensive patients: AT1 subtype angiotensin II receptor…
- Conditions
- Hypertension, Cardiovascular Disease, Diabetes
- Trial name
- NCT00454662
- Testing
- olmesartan medoxomil / amlodipine or azelnidipine, olmesartan medoxomil / low dose thiazide type drug
- Where
- Japan
- Volunteers
- 5,141 people
- Sponsor
- COLM Study Research Organization
Hypertensive Intracerebral Hemorrhage, Intraventricular Hemorrhage
Neuroinflammatory Response in Patients With ICH and IVH Treated With rtPA
This study compares the neuroinflammatory response in patients with hypertensive ICH associated with IVH treated with intraventriculary applied rtPA, and the control group.
- Conditions
- Hypertensive Intracerebral Hemorrhage, Intraventricular Hemorrhage, Brain Injuries
- Trial name
- NCT03452722
- Testing
- intraventricual recombinant tissue plasminogen activator application
- Volunteers
- 88 people
- Sponsor
- University of Rijeka
Hypertension, Vitamin D Deficiency
Effects of Vitamin D on Renin Expression in Hypertensive Patients
The cardiovascular effects of vitamin D therapy (in humans) have been documented only in patients with known vitamin D deficiency or hyperparathyroidism (a surrogate marker of inadequate vitamin D activity).
- Trial name
- NCT00585442
- Testing
- calcitriol
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Utah