Clinical trials: Hypertensive Heart Disease
Cardiovascular Diseases, Heart Diseases
Preventing Weight Gain and Controlling Blood Pressure During Smoking Cessation in Hypertensive Smokers
The purpose of this study is to develop effective interventions that assist individuals with high blood pressure to quit smoking and prevent weight gain.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00113074
- Testing
- Nicotine Replacement Therapy, Diet
- Where
- 2 sites in United States
- Volunteers
- 139 people
- Sponsor
- Mark Vander Weg
Heart Disease (Coronary Artery Disease, Ischemic Heart Disease, Hypertensive Heart Disease), Uncontrolled Diabetes (HBA1c ≥ 10)
Piloting the IPROACTIF Program to Preserve Functioning and Prevent Cognitive Decline
Conduct a pilot randomized control to assess the preliminary efficacy of IPROACTIF, an occupational therapist-delivered primary care intervention for aging and chronic disease management.
- Trial name
- NCT04682977
- Testing
- IPROACTIF (Integrated PRimary Care and Occupational Therapy for Aging and Chronic Disease Treatment to preserve Independence and Functioning), Usual primary care services
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Illinois at Chicago
Diabetes Mellitus, Non-Insulin-Dependent, Hypertensive Disease
To Evaluate the Effect of Liraglutide on Ambulatory Blood Pressure-A Pilot Study
The investigators are conducting this research to study the effect of Liraglutide on blood pressure. Several studies have shown increased cardiovascular complications and deaths in diabetics with hypertension.
- Trial name
- NCT02299388
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Tulane University School of Medicine
Hypertension, Coronary Artery Disease
The Effect of Nebivolol in Hypertensive Patients With Coronary Artery Disease
This study is being done to see if the blood pressure lowering effect of an approved drug nebivolol is comparable to that of another approved drug carvedilol for the treatment of hypertension in patients who have coronary artery…
- Trial name
- NCT00673075
- Testing
- Nebivolol, Carvedilol
- Where
- 34 sites in United States
- Volunteers
- 39 people
- Sponsor
- Forest Laboratories
Heart Failure
Dietary Prevention of Heart Failure in Hypertensive Metabolic Syndrome
Tens of thousands of Veterans have heart failure with preserved ejection fraction (HFpEF), and suffer poor quality of life, frequent hospitalizations, and high death rates.
- Trial name
- NCT03170375
- Testing
- Performance of WHEELS-I in promoting DASH/SRD adoption
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- VA Office of Research and Development
Hypertension, Left Ventricular Diastolic Dysfunction
Effect of Nebivolol on the Blood Flow in Hearts of Adults With High Blood Pressure and Abnormal Filling of Heart
To investigate whether treatment with Nebivolol in subjects with high blood pressure and abnormal filling of left ventricle (LVDD) improves exercise time by improving Left Ventricular deformation and filling.
- Trial name
- NCT01961323
- Testing
- Nebivolol
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypertension
Clevidipine Bolus Administration in the Treatment of Hypertensive Patients Undergoing Cardiac Surgery (SPRINT)
This study was designed to evaluate the pharmacodynamics of a bolus dosing regimen of clevidipine, a vascular-selective L-type calcium channel antagonist, for the management of blood pressure in cardiac surgery patients, as well…
- Trial name
- SPRINT (NCT00799604)
- Testing
- clevidipine
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- The Medicines Company
Infection, Heart Failure
Rural Home Hospital: Proof of Concept
This study examines the implications of providing hospital-level care in rural homes.
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT04531280
- Testing
- Home hospital care
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Brigham and Women's Hospital
Hypertension, High Blood Pressure
Pre-clinical Cardiac Dysfunction Among Asymptomatic Hypertensive Patients
This project will evaluate the clinical and cost effectiveness of a novel, multidisciplinary approach to identify and treat pre-clinical cardiac dysfunction (PCCD) in asymptomatic hypertensive patients identified in a single…
- Conditions
- Hypertension, High Blood Pressure, Ventricular Hypertrophy, Diastolic Dysfunction
- Trial name
- NCT00689819
- Testing
- Exercise, Weight Loss, Low Sodium Diet
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Hypertrophy, Left Ventricular
The CLEVER Study - Coreg And Left Ventricular Mass Regression
This study is designed to compare the effects of COREG MR (carvedilol modified release formulation) to atenolol on indices of left ventricular dimensions when added to standardized angiotensin converting enzyme (ACE) inhibition…
- Trial name
- NCT00108082
- Testing
- carvedilol MR, atenolol, lisinopril
- Where
- 78 sites in United States
- Volunteers
- 287 people
- Sponsor
- GlaxoSmithKline
Hypertension
Irbesartan and Atenolol in Hypertensive Heart Disease
The renin-angiotensin-aldosterone system has been implicated in the control of structural changes of the heart and the vasculature, beyond the effects on blood pressure.
- Trial name
- SILVHIA (NCT00389168)
- Testing
- Irbesartan, Atenolol
- Where
- Sweden
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Hypertension
Comparison of Bisoprolol With Metoprolol Succinate Sustained-release on Heart Rate and Blood Pressure in Hypertensive Patients
This is a multicentre, randomized, open-label parallel trial to demonstrate the superiority and/or non-inferiority of bisoprolol on metoprolol succinate sustained-release (SR) tablet in subjects with mild to moderate primary…
- Trial name
- CREATIVE (NCT01508325)
- Testing
- Bisoprolol, Metoprolol
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Hypertension, Chronic Kidney Disease
Effects of Aliskiren in Elderly Hypertensive Chronic Kidney Disease (CKD) Patients
The purpose of this study is to determine whether aliskiren is effective in the treatment of blood pressure, hear function, renal function in elderly hypertensive chronic kidney disease (CKD) patients.
- Trial name
- NCT01284114
- Testing
- Aliskiren
- Where
- 4 sites in Japan
- Volunteers
- 23 people
- Sponsor
- Jichi Medical University
Diastolic Heart Failure, Hypertensive Heart Disease
Effects of the Dietary Approaches to Stop Hypertension(DASH) Sodium-restricted Diet in Diastolic Heart Failure
Heart failure with preserved systolic function (HF-PSF, or 'diastolic heart failure') accounts for half of hospitalizations for heart failure in patients over the age of 65.
- Trial name
- DASH-DHF (NCT00939640)
- Testing
- DASH/sodium-restricted diet (SRD)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Michigan