Clinical trials: Hypertensive Kidney Disease
Chronic Kidney Diseases
Telemonitoring of Hypertensive Patients With Chronic Kidney Disease
Background: Hypertension, together with poorly controlled blood pressure (BP) are known risk factors for kidney disease and progression to kidney failure as well as increased cardiovascular (CV) morbidity and mortality.
- Trial name
- NCT04098354
- Testing
- home BP telemonitoring system .
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- University of Alberta
Albuminuria, Chronic Kidney Diseases
Improving Albuminuria Screening Compliance Using a Smartphone Urinalysis Kit
This study will test the effectiveness of mailed, smartphone urinalysis kits to improve albuminuria screening compliance and detection of albuminuria.
- Conditions
- Albuminuria, Chronic Kidney Diseases, Cardiovascular Diseases, Hypertension
- Trial name
- NCT03470701
- Testing
- Mailed Urinalysis Smartphone Kit
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- Geisinger Clinic
Hypertensive Nephropathy, Auto Immune Disorders
ACE Reno, Pico Cell Matrix and Its Effect on eGFR in Chronic Kidney Diseases
This study investigates the safety and efficacy of ACE Reno, an oral transmucosal solution containing standardized bioactive peptides and amino acids, in patients with nephropathy of various etiologies and stages.
- Conditions
- Hypertensive Nephropathy, Auto Immune Disorders, Chronic Kidney Disease, Chronc Kidney Disease Stage 5
- Trial name
- ACE Reno (NCT07187713)
- Testing
- ACE Reno
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Ace Cells Lab Limited
Hypertension;Nephropathy
Nighttime Valsartan in Hemodialysis Hypertension
Hypertension is one of the most important independent risk factors for the prognosis of maintenance hemodialysis patients. The incidence rate is high and the control rate is low.
- Trial name
- NVHH (NCT03594825)
- Testing
- Valsartan
- Volunteers
- 68 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Hypertension, Obesity
Renal Response to Lower Body Negative Pressure in Pre-hypertensive States
The purpose of this study is to determine whether in pre-hypertensive and hypertensive states such as white coat hypertension, obesity related hypertension or resistant hypertension, renal function is more sensitive to…
- Conditions
- Hypertension, Obesity, White Coat Hypertension, Resistant Hypertension
- Trial name
- NCT01734096
- Testing
- Lower body negative pressure (LBNP), Candesartan cilexetil
- Where
- 2 sites in Switzerland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- PD Dr. Grégoire Wuerzner
Infection, Heart Failure
Hospital-Level Care at Home for Acutely Ill Adults
The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be…
- Conditions
- Infection, Heart Failure, COPD, Asthma
- Trial name
- NCT03203759
- Testing
- Home hospitalization, Traditional inpatient hospitalization
- Where
- 2 sites in United States
- Volunteers
- 91 people
- Sponsor
- Brigham and Women's Hospital
Homocysteine, Coronary Disease
The Relationship Between HHcy and Contrast-induced Nephropathy in Hypertensive Patients After Coronary Artery Diagnosis and Treatment
Contrast-induced nephropathy has become the third-largest cause of hospital acquired acute renal injury, and which morbidity is only less than that of renal hypoperfusion and renal toxicity of drugs, about 11%of all cases.
- Conditions
- Homocysteine, Coronary Disease, Angioplasty,Balloon,Coronary, Contrast Media
- Trial name
- CONTRAST-CADT (NCT02575092)
- Testing
- Enalapril Maleate Tablets(as the program-based antihypertension), Enalapril Maleate and Folic Acid tablets(as the program-based antihypertension)
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Fuling Central Hospital of Chongqing City
Kidney, Polycystic, Autosomal Dominant
CCB Safety Study in Treatment of Hypertension of ADPKD
This study examines the safety and efficacy of calcium channel blocker (CCB) in the treatment of hypertension of Autosomal Dominant Polycystic Kidney Disease (ADPKD) patients.
- Trial name
- NCT00541853
- Testing
- Candesartan, Candesartan and Cilnidipine, Candesartan plus non-CCB agents
- Where
- 6 sites in Japan
- Volunteers
- 150 people
- Sponsor
- Kyorin University
Infection, Heart Failure
Rural Home Hospital: Proof of Concept
This study examines the implications of providing hospital-level care in rural homes.
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT04531280
- Testing
- Home hospital care
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Brigham and Women's Hospital
Hypertension, Hypertension Resistant to Conventional Therapy
High Prevalence of Secondary Arterial Hypertension (HIPRESH) with Prospective Systematic Screening in a Cohort of Consecutive Hypertensive Patients Referring to Regional Specialized Center
Hypertensive Patients referring to our center will undergo a systematic diagnostic workup aimed at finding the cause(s) of their high blood pressure.
- Conditions
- Hypertension, Hypertension Resistant to Conventional Therapy, Secondary Hypertension to Endocrine Disorders, Secondary Hypertension
- Trial name
- HIPRESH (NCT06664255)
- Volunteers
- 1,400 people
- Sponsor
- University Hospital Padova
Diabetes Type 2, Hypertension
Acetyl-L-Carnitine in Type 2 Diabetes
Decreased insulin sensitivity (or insulin resistance) is a major risk factor for type 2 diabetes mellitus and renal and cardiovascular disease.
- Trial name
- DIABASI (NCT00984750)
- Testing
- acetyl-L-carnitine/statin (simvastatin)
- Where
- 5 sites in Italy
- Volunteers
- 229 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Non-diabetic Nephropathy With Hypertension
ARIA (Atacand Renoprotection In NephropAthy Pt.)
To determine the effective dose of candesartan cilexetil for reduction of urinary protein excretion in hypertensive patients with non-diabetic chronic kidney disease with baseline urinary protein/creatinine ratio between 500mg/g…
- Trial name
- PCR (NCT00573430)
- Testing
- Candesartan Cilexetil, Candesartan Cilexetil 32mg
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- AstraZeneca
Hypertension
Study of CS-3150 in Hypertensive Patients With Type 2 Diabetes and Albuminuria
To examine antihypertensive effect and safety of administration of CS-3150 in combination with ARB or ACE inhibitor in hypertensive patients with type 2 diabetes and albuminuria.
- Trial name
- NCT02807974
- Testing
- CS-3150
- Where
- Japan
- Volunteers
- 51 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Proteinuria
Safety and Pharmacokinetic Study of Subcutaneous ALXN1720 in Participants With Proteinuria
The primary objective of this study is to assess the impact of proteinuria on the pharmacokinetic (PK) of a single dose of ALXN1720 in participants with proteinuria.
- Trial name
- NCT05314231
- Testing
- ALXN1720
- Where
- 2 sites in South Korea
- Volunteers
- 13 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Kidney Disease, Chronic, Diabetic Kidney Disease (DKD)
Mesenchymal Stem Cells for Chronic Kidney Diseases
This study will evaluate the effect of intravenous injection of umbilical cord tissue derived mesenchymal stem cells (UMSCs) on the improvement of renal function in patients with chronic kidney disease (CKD) at stage 3 or 4, with…
- Conditions
- Kidney Disease, Chronic, Diabetic Kidney Disease (DKD), Hypertensive Nephropathy
- Trial name
- NCT07240987
- Testing
- 0.9% sodium chloride, MSCs
- Volunteers
- 32 people
- Sponsor
- The First Affiliated Hospital of Air Force Medical University
Diabetes Mellitus, Hypertension
Quantitative Renal Uptake Using TC99m DMSA in Hypertensive &/or Diabetic Patients.
the investigators explore the possible role of DMSA to detect renal affection in diabetic \&/or hypertensive patients by detecting difference in counts using Tc 99m DMSA in control \& diabetic \&/or hypertensive patients.
- Trial name
- NCT03123237
- Testing
- DMSA scan
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Assiut University
Hypertensive Nephropathy, Self-management
Effectiveness of Implementation of a Patient-centered Self-management Program in Patients With Hypertensive Nephropathy
This study is a 2-years project. The year 1 project: to assess the effectiveness of implementation of the program in patients with HN.
- Conditions
- Hypertensive Nephropathy, Self-management, Self-efficacy, Mental Health Wellness 1
- Trial name
- NCT04633993
- Testing
- PCSMP
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Chronic Kidney Failure
Clinical Evaluation of Low Sodium Peritoneal Dialysis (PD) Solution on Hypertensive Patients Treated With PD
The aim of this study is to assess the superiority of the new low sodium peritoneal dialysis (PD) solution PDsol 12 in comparison with a conventional, already marketed solution, Gambrosol trio 40, in the treatment of the…
- Trial name
- PDOne (NCT00794326)
- Testing
- Solution for Peritoneal Dialysis
- Where
- 29 sites in Denmark, France and 3 more
- Volunteers
- 140 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Hypertension, Blood Pressure
The Effects of Sodium and Potassium on Blood Pressure, Vascular Function and Renal Function
To determine the effect of (1) increased sodium intake and (2) increased potassium intake on blood pressure, vascular function and renal function in untreated (pre)hypertensive subjects.
- Conditions
- Hypertension, Blood Pressure, Vascular Function, Renal Function
- Trial name
- KaNa (NCT01575041)
- Testing
- Sodium, Potassium
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Catecholamine; Overproduction, Catecholamine; Secretion
Sympathetic Activity and Cardiometabolic Complications
Recent studies on catecholamine physiology have shown a direct correlation with arterial hypertension, overcoming the exclusive role in the diagnosis and follow-up of chromaffin tumors.
- Conditions
- Catecholamine; Overproduction, Catecholamine; Secretion, Metabolic Syndrome, Hypertensive Heart Disease
- Trial name
- SYMPACT (NCT04495231)
- Where
- Italy
- Volunteers
- 1,380 people
- Sponsor
- University of Turin, Italy