Clinical trials: Hypertensive Patients
Hypertension
One Year Study to Evaluate the Safety of the Combination of Valsartan and Amlodipine in Patients With Hypertension
A ONE YEAR SAFETY STUDY FOR PATIENTS WHO COMPLETE STUDY VAA489A2201.
- Trial name
- NCT00409851
- Testing
- valsartan+amlodipine
- Where
- 2 sites in United States, Germany
- Volunteers
- 1,293 people
- Sponsor
- Novartis
Hypertension
Randomized, Parallel, Comparison, Double-Blind Efficacy & Safety Study of APROVEL Versus Placebo in Chinese Patients With Hypertensive Type II Diabetic Patients With Microalbuminuria
To evaluate the effects and safety of irbesartan on proteinuria in hypertensive patients with type Ⅱdiabetes mellitus.
- Trial name
- PRIME (NCT00561964)
- Testing
- Irbesartan
- Volunteers
- 241 people
- Sponsor
- Sanofi
Hypertension, Diabetes Mellitus
Comparison of Amlodipine and Aliskiren in Diabetic Hypertensive Patient With Blood Pressure Not Controlled by Losartan
Assess if aliskiren is capable of enhancing vascular stiffness and endothelial function and compare theses effects and renin activity and concentration to those obtained with a calcium channel blocker, amlodipine, in patients…
- Trial name
- NCT01409408
- Testing
- Aliskiren, Amlodipine
- Where
- Brazil
- Sponsor
- Hospital Universitario Pedro Ernesto
Hypertension, Hyperlipidemia
Efficacy and Safety of Telmisartan/Rosuvastatin Co-administration in Hypertensive Patients With Hyperlipidemia
To identify efficacy and safety of Telmisartan/Rosuvastatin co-administration in hyperlipidemia control in hypertensive patients with hyperlipidemia compared to each monotherapy.
- Trial name
- NCT02087540
- Testing
- Telmisartan 80mg, Rosuvastatin 20mg, Rosuvastatin 10mg
- Where
- South Korea
- Volunteers
- 310 people
- Sponsor
- IlDong Pharmaceutical Co Ltd
Hypertension
Flaxseed in Controlling Blood Pressure of Patients
Hypertension is one of the major risk factor for global mortality. Approximately half of 17 million cardiovascular deaths worldwide are accounted for HTN.
- Trial name
- NCT04759508
- Testing
- Flax Oil Capsule
- Volunteers
- 72 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Hypertension; Heart Disease, Hypertensive
Effect of Aterial Stiffness on Myocardial Work in Patients With Hypertension
Hypertension is a serious threat to human health and a major global economic burden.Chronic hypertension can cause left ventricular remodeling and loss of function, eventually leading to heart failure.Exploring the early changes…
- Trial name
- NCT04573257
- Testing
- Echocardiography and pulse wave velocity measurement
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chongqing Medical University
Hypertension
Clinical Response of EXTOR (Amlodipine/Valsartan) in Newly Diagnosed Hypertensive Patients.
The American College of Cardiology/American Heart Association hypertension guidelines recommend treatment initiation with dual antihypertensive therapy in adults with stage 2 hypertension (corresponding to grade 1 and 2 in the…
- Trial name
- HELP (NCT06625346)
- Testing
- Fixed-Dose Combination of Amlodipine/Valsartan
- Where
- 2 sites in Pakistan
- Volunteers
- 420 people
- Sponsor
- The Searle Company Limited Pakistan
Hypertension, End Stage Renal Disease
Study of the Effect of Intradialytic Vasopressin on Chronic Hypertension in Patients With End Stage Renal Disease
The death rate of patients with endstage renal disease (ESRD) on dialysis each year is 20%, with diseases related to the heart and blood vessels causing about half.
- Trial name
- NCT01247090
- Testing
- Vasopressin - Very Low Dose, Vasopressin - Low Dose
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Columbia University
Hypertension
COugh Among Hypertensive Patients Treated With Telmisartan, Who Had to Stop previoUs ACE-i Treatment Due to couGH in Slovakia
In the light of ONTARGET and TRANSCEND studies results, it would be interesting to investigate the real-life telmisartan treatment tolerability.
- Trial name
- COUGH (NCT01217879)
- Testing
- Telmisartan (Kinzal/Pritor, BAY68-9291)
- Where
- Slovakia
- Volunteers
- 980 people
- Sponsor
- Bayer
Hypertension
Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines Level
Aim: To evaluate the effects of Valsartan versus Amlodipine on LV deformation in relation to plasma adiponectin and leptin levels in hypertensive individuals.
- Trial name
- NCT03990480
- Testing
- valsartan (160 mg/d), amlodipine (10 mg/d).
- Where
- Egypt
- Volunteers
- 230 people
- Sponsor
- Damanhour University
Metabolic Syndrome, Hypertension
Irbesartan in the Treatment of Hypertensive Patients With Metabolic Syndrome
The purpose of this clinical research study is to learn if irbesartan is superior to hydrochlorothiazide relative to effects on insulin sensitivity and glucose metabolism in hypertensive patients with metabolic syndrome.
- Trial name
- NCT00110422
- Testing
- Irbesartan, Hydrochlorothiazide
- Where
- 25 sites in France, Germany and 4 more
- Volunteers
- 400 people
- Sponsor
- Bristol-Myers Squibb
Hypertension
Trial to Evaluate the Efficacy and Safety of a Combination Therapy of Candesartan and Amlodipine Versus Candesartan Monotherapy in Hypertensive Patients Inadequately Controlled by Candesartan Monotherapy
A Phase 3 Trial to Evaluate the Efficacy and Safety of a Combination Therapy of Candesartan and Amlodipine Versus Candesartan Monotherapy in Hypertensive Patients Inadequately Controlled by Candesartan Monotherapy
- Trial name
- NCT02651870
- Testing
- Candesartan 16mg, Amlodipine 5mg, Amlodipine 10mg
- Where
- South Korea
- Volunteers
- 135 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Arterial Hypertension, HTN
Evaluation of the Antihypertensive effectIveness, Tolerability, and Adherence With Amlodipine/ Indapamide/ Perindopril Triple Single-pill Combination in Hypertensive Patients Without Concomitant Antihypertensive Therapy (TRIPTYCH)
This is a multi-centre, observational, ambispective study, which will retrospectively and prospectively collect clinical and socio-demographic data from medical records of outpatients with arterial hypertension (HTN) initiated…
- Trial name
- TRIPTYCH (NCT06259175)
- Testing
- Amlodipine 5 mg + indapamide 1.25 mg + perindopril 5 mg, Amlodipine 5 mg + indapamide 2.5 mg + perindopril 10 mg, Amlodipine 10 mg + indapamide 2.5 mg + perindopril 10 mg
- Where
- Russia
- Volunteers
- 396 people
- Sponsor
- Servier Russia
Hypertension, Blood Pressure
Effect of Smart Phone Based Telemonitoring on Blood Pressure Among Hypertensive Patients in Primary Care
To test the hypothesis that hypertensive patients who participate in smart phone based telemonitoring of BP will conduct more home blood pressure monitoring, better self management behavior and greater reduction in blood pressure…
- Trial name
- NCT02046993
- Testing
- Smart phone telemonitoring HBP + enhanced usual care, Enhanced usual care
- Where
- Hong Kong
- Volunteers
- 210 people
- Sponsor
- Kwong Wah Hospital
Hypertension
Evaluation of the Effect of Telmisartan on Blood Pressure Control of High Risk Patients
The study is designed to evaluate the effect of treatment with Micardis/MicardisPlus on blood pressure and its ability to reduce different indicated cardiovascular risk scores.
- Trial name
- NCT01108809
- Testing
- Telmisartan or Telmisartan and Hydrochlorthiazide
- Where
- 49 sites in Romania
- Volunteers
- 295 people
- Sponsor
- Boehringer Ingelheim
Hypertension
Compliance of Blood Pressure and Lipid in Hypertensive Patients Under the Management of Hospitals at Different Levels
This is a multi-center, prospective cohort study that collects only diagnostic and therapeutic data in subjects but does not interfere with treatment.
- Trial name
- NCT04015843
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- China Cardiovascular Association
Hypertension
Effects of Telemonitoring and Telemedicine Service for Hypertensive Care
This is a multi-centered, randomized, parallel group, interventional \& open label clinical trial accessing efficacy of intervention effect by smart care system over existing treatment group for lowering blood pressure of…
- Trial name
- Smart-HTN (NCT01335984)
- Testing
- Telemonitoring, Telemonitoring & Telemedicine, control group
- Where
- 3 sites in South Korea
- Volunteers
- 440 people
- Sponsor
- Chang Hee, Lee
Hypertension
Canadian Study of Trandolapril on Blood Pressure in Hypertensive Patients (TRAIL)
The TRAIL study was conducted to examine the effects of escalating doses of an ACE inhibitor, trandolapril, on lowering blood pressure in Stage 1-2 hypertensive patients.
- Trial name
- TRAIL (NCT00233532)
- Testing
- Trandolapril
- Volunteers
- 2,000 people
- Sponsor
- Abbott
Hypertension
The Effect of a Complementary Multi Disciplinary Program on Blood Pressure in Hypertensive Patients
Intervention description: Complementary Approaches to Lower Mean arterial pressure (CALM) is a multi dispensary program aimed to reduce blood pressure in hypertensive patients.
- Trial name
- NCT00409149
- Testing
- CALM Approache, DASH approach
- Where
- Israel
- Volunteers
- 113 people
- Sponsor
- Assaf-Harofeh Medical Center
Hypertension
Antihypertensive Efficacy and Safety of Approved Drugs in Japanese Patients With Essential Hypertension (Banyu Study)(0954A-302)
The purpose of this study is to evaluate antihypertensive (lowering blood pressure) effectiveness of three combinations of approved study drugs compared to both study drugs being given alone.
- Trial name
- NCT00092209
- Testing
- MK0954A, hydrochlorothiazide (+) losartan potassium
- Volunteers
- 840 people
- Sponsor
- Organon and Co