Clinical trials: Hypertensive Patients
Hypertension
Nice Morning- Safety and Efficacy Observational Study of Telmisartan in Hypertensive Patients in Multicenters
The purpose of this observational study is to survey the safety and effectiveness of the product under the real condition of usual practice in Taiwanese hypertensive patients.
- Trial name
- NCT00615108
- Where
- 17 sites in Taiwan
- Volunteers
- 3,148 people
- Sponsor
- Boehringer Ingelheim
Hypertension
BEtter Control of Blood Pressure in Hypertensive pAtients Monitored Using the HOTMAN® sYstem
The purpose of this study is to demonstrate that monitoring hemodynamic parameters and then applying a predefined algorithm of drug selection (i.e.
- Trial name
- BEAUTY (NCT01482364)
- Testing
- Integrated hemodynamic management (IHM) - HOTMAN System, Non Integrated Hemodynamic Management (Non-IHM) - HOTMAN System
- Where
- 5 sites in Estonia, France and 3 more
- Volunteers
- 183 people
- Sponsor
- Hemo Sapiens, Inc.
Hypertension, High Blood Pressure
Pre-clinical Cardiac Dysfunction Among Asymptomatic Hypertensive Patients
This project will evaluate the clinical and cost effectiveness of a novel, multidisciplinary approach to identify and treat pre-clinical cardiac dysfunction (PCCD) in asymptomatic hypertensive patients identified in a single…
- Conditions
- Hypertension, High Blood Pressure, Ventricular Hypertrophy, Diastolic Dysfunction
- Trial name
- NCT00689819
- Testing
- Exercise, Weight Loss, Low Sodium Diet
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Hypertension
An Extension Study to Evaluate the Long Term Safety, Tolerability and Efficacy of Aliskiren Compared to Enalapril in Pediatric Hypertensive Patients 6-17 Years of Age
The purpose of this study is to evaluate in a randomized, double-blind fashion, the long-term safety, tolerability and efficacy profile of aliskiren compared to the active comparator enalapril in children, 6 - 17 years old with…
- Trial name
- NCT01151410
- Testing
- Aliskiren, Enalapril
- Where
- 36 sites in United States, Guatemala and 5 more
- Volunteers
- 208 people
- Sponsor
- Novartis Pharmaceuticals
Arterial Hypertension, Hypertension
Validity of 6 Minutes Stepper Test in Hypertension
The six minutes stepper test (6MST) was used assess exercise capacity of individuals having different chronic conditions. In the literature, there are some validation studies analyzing validity of 6MST.
- Trial name
- NCT06087172
- Testing
- Six Minutes Stepper Test (6MST)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ebru Calik Kutukcu
Severe Hypertension
Safety and Tolerability and Efficacy of LCZ696 in Japanese Severe Hypertensive Patients
This study assessed the safety, tolerability, and efficacy of LCZ696 in severe hypertensive Japanese patients
- Trial name
- NCT01646671
- Testing
- LCZ696
- Where
- 9 sites in Japan
- Volunteers
- 35 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension
Novel Approaches of Advanced Neuroimaging Based on MRI Fiber Tracking to Detect Early Signs of Vascular Cognitive Impairment in Hypertensive Patients
Hypertension is the major risk factor for vascular cognitive impairment (VCI). One of the main limitations in the clinical approach to VCI is that, by the time that it is manifested, it might be too late to reverse the…
- Trial name
- NCT03986957
- Testing
- No interventions
- Where
- Italy
- Volunteers
- 176 people
- Sponsor
- Neuromed IRCCS
Hypertension, Hypertriglyceridemia
Fish Oil Supplementation and Vascular Function in Hypertensive Patients With Hypertriglyceridemia
The objective of this study is to compare the effects of ciprofibrate versus omega-3 fatty acid supplementation on the vascular structure and function in hypertensive patients with hypertriglyceridemia.
- Trial name
- NCT01480687
- Testing
- DHA-EPA, Ciprofibrate
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Hospital Universitario Pedro Ernesto
Hypertension, Obesity
Trial Comparing Metabolic Effects of Telmisartan and Amlodipine on Hypertensive Patients With Obesity and Diabetes
Recent studies have shown that obese people are more prone to high blood pressure. With the co-existence of obesity, hypertension and diabetes, patients were more susceptible to hyperlipidemia, coronary and cerebral…
- Conditions
- Hypertension, Obesity, Diabetes
- Trial name
- HOT-DM (NCT00847262)
- Testing
- Temisartan, Amlodipine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Third Military Medical University
Glaucoma
Efficacy and Safety of Travoprost 0.004% Versus Tafluprost 0.0015% in Patients With Primary Open-angle Glaucoma or Ocular Hypertension
The purpose of this study is to assess the safety and efficacy of Travoprost 0.004% and Tafluprost 0.0015% in patients with primary open angle glaucoma or ocular hypertension when both medications are administered in the evening.
- Trial name
- NCT00966940
- Testing
- Travoprost 0.004% ophthalmic solution (TRAVATAN), Tafluprost 0.0015% ophthalmic solution
- Volunteers
- 51 people
- Sponsor
- Alcon Research
Arterial Hypertension, Medication Nonadherence
Feasibility of a Program on a Nurse-led Telephone 6-month-follow-up for Uncontrolled Hypertensive Women
This study evaluate the feasibility of a 6-month personalized support program for hypertensive and non-observant women, led by nurses by telephone follow-up.
- Trial name
- PreDynamiques (NCT03963934)
- Testing
- Program on a nurse-led telephone 6-month-follow-up for uncontrolled hypertensive women: a patient-tailored intervention
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Mme Edith DAUCHY
Hypertensive Emergency
The Value of TOI in Evaluating Renal Function Damage in Hypertensive Emergency Patients
TOI was used to measure heart rate, respiration, blood pressure, heart rate variability and psychological stress. At the same time, the patient's urine protein, creatinine, urea nitrogen and other indicators were detected.
- Trial name
- NCT06201572
- Testing
- The relationship between TOI composite index and renal function in hypertensive emergency patients was compared
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Hangzhou Normal University
Hypertension
Safety & Efficacy of Qurs e Fishar in Mild to Moderate Hypertensive Patients in Pakistan
The herbal medicine Qurs-e-Fishar to treat mild to moderate High blood pressure or hypertension comprises of Rauwolfia serpentina. A product of Hamdard Laboratories (Waqf) Pakistan.
- Trial name
- NCT06852079
- Testing
- Qurs e Fishar
- Where
- Pakistan
- Volunteers
- 119 people
- Sponsor
- Abdul Bari
Diabetes, Hypertension
Adherence and Intensification of Medications (AIM) Implementation Study
Background: Good blood pressure (BP) control among patients with diabetes is essential in preventing diabetes complications and has been found to be not only cost-effective but cost-saving.
- Trial name
- NCT00495794
- Testing
- Clinical pharmacist-based intervention
- Where
- United States
- Volunteers
- 4,622 people
- Sponsor
- US Department of Veterans Affairs
Arterial Hypertension, Resistant Hypertension
Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity.
- Conditions
- Arterial Hypertension, Resistant Hypertension, Microvascular Function, Nitrate Supplementation
- Trial name
- NCT06169241
- Testing
- Beetroot extract
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Hypertension, Arteriosclerosis
The Effects of Lowering Dialysate Sodium in Hypertensive Hemodialysis Patients
Unfavorably high sodium intakes remain prevalent around the world. A negative sodium gradient in hemodialysis treatment results in absolute sodium removal via diffusive transport of sodium from the blood to the dialysate, and it…
- Conditions
- Hypertension, Arteriosclerosis, Left Ventricular Hypertrophy
- Trial name
- NCT01455974
- Testing
- Decreasing dialysate sodium from 138 mmol/L to 136 mmol/L
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Capital Medical University
PROTEINURIA, Hypertension
Effect of Valsartan on Proteinuria in Patients With Hypertension and Diabetes Mellitus
This is a study of whether valsartan affects levels of proteinuria in patients with type 2 diabetes and hypertension.
- Conditions
- PROTEINURIA, Hypertension, Type 2 Diabetes
- Trial name
- NCT00241085
- Testing
- valsartan
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Novartis
Hypertension, Cardiovascular Diseases
Evaluation of the Effect of Telmisartan (Micardis® 80 mg/ MicardisPlus® 80/12.5 mg) on Blood Pressure and Cardiovascular Risk Factor Index in High Risk Hypertensive Patients
The study is designed to evaluate the effect of treatment with Micardis/MicardisPlus on blood pressure and its ability to reduce different indicated cardiovascular risks.
- Trial name
- NCT00904371
- Where
- 36 sites in Slovenia
- Volunteers
- 211 people
- Sponsor
- Boehringer Ingelheim
Hypertension
Comparison of Two Treatment Strategies in Hypertensive Patients
The purpose of the study is to determine whether a specific training of General Practitioners (Family Physicians) regarding the new official guidelines for the treatment of hypertension results in a higher control of high Blood…
- Trial name
- NCT00171444
- Testing
- Medical education
- Volunteers
- 4,445 people
- Sponsor
- Novartis
Essential Hypertension
The Prevalence of Sympathetic Overactivity in Primary Hypertensive Patients.
The purpose of this NIS is to assess the prevalence of sympathetic overactivity in patients with newly diagnosed essential hypertension.
- Trial name
- SORT (NCT01295021)
- Where
- 97 sites in India
- Volunteers
- 1,514 people
- Sponsor
- AstraZeneca