Clinical trials: Hypertensive Patients
Glaucoma, Ocular Hypertension
Intraocular Pressure Measured by a Novel Sensing Contact Lens Versus Tonometry
While elevated intraocular pressure (IOP) is no longer part of the definition of glaucoma it remains the sole proven modifiable risk factor for the onset and progression of glaucoma.
- Trial name
- NCT04024293
- Testing
- Goldfish (GF)
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Sensimed AG
Uncontrolled Hypertension, High Blood Pressure
SCRATCH-HTN Study: Evaluating Autonomic Neuromodulation Using Trans-cutaneous Vagal Stimulation in Hypertensive Patients
This is a pilot, sham-controlled, double blind, single-site device clinical trial designed to evaluate the safety, acceptability and efficacy of non-invasive autonomic neuromodulation in a cohort of 63 adult patients with…
- Trial name
- SCRATCH-HTN (NCT05179343)
- Testing
- Active AffeX-CT device
- Where
- United Kingdom
- Volunteers
- 63 people
- Sponsor
- Queen Mary University of London
Hypertension
Study of CS-3150 in Hypertensive Patients With Type 2 Diabetes and Albuminuria
To examine antihypertensive effect and safety of administration of CS-3150 in combination with ARB or ACE inhibitor in hypertensive patients with type 2 diabetes and albuminuria.
- Trial name
- NCT02807974
- Testing
- CS-3150
- Where
- Japan
- Volunteers
- 51 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Hypertension
Effect of Nocturnal Administration of Anti-hypertensive Medications in NoN-dippers
The purpose of this study is to determine the effect of nocturnal administration of Anti-hypertensive medications in Non-dippers. Efficacy variables. 1. ECHO 2. 24hr. horter 3. IMT 4. BUN/crea, urine analysis (microalbulinuria 5.
- Trial name
- NCT01091753
- Testing
- Valsaltan, amlodipine
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Yonsei University
Medication Adherence, Adherence, Treatment
mHealth App Intervention to Improve Medication Adherence
It is a parallel-design, two-arm, randomized controlled trial designed to assess the effectiveness of mHealth application using 7- items, multifaceted educational and reminder module intervention( written message, voice message…
- Trial name
- NCT04577157
- Testing
- mHealth using"WhatsApp" multifaceted educational and reminder module intervention to improve adherence
- Where
- Pakistan
- Volunteers
- 440 people
- Sponsor
- Universiti Putra Malaysia
Hypotension, Orthostatic, Hypertension
Effects of Melatonin to Reduce Nocturnal Hypertension in Patients With Neurogenic Orthostatic Hypotension
Neurogenic Orthostatic Hypotension (NOH) is clinically defined as a consistent drop in systolic blood pressure (SBP) ≥30mmHg upon standing from a seated or lying position.
- Conditions
- Hypotension, Orthostatic, Hypertension, Autonomic Nervous System Diseases
- Trial name
- NCT02963181
- Testing
- Yohimbine, Melatonin
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hypertension
Research Study To Test Carvedilol CR + Lisinopril Versus Lisinopril + Placebo In Patients With High Blood Pressure
Randomized, double-blind, parallel group, multicenter study of subjects with Stage 1 or 2 essential hypertension who are not at target blood pressure (<140/90mmHg) at Baseline.
- Trial name
- NCT00624065
- Testing
- carvedilol controlled release/lisinopril
- Where
- 76 sites in United States
- Volunteers
- 348 people
- Sponsor
- GlaxoSmithKline
Cardiovascular Disease, Chronic Kidney Disease
Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease
Introduction: Chronic kidney disease (CKD) is now an important public health issue. While 0.1% of the population is on dialysis, approximately 4.5% of subjects have renal dysfunction (glomerular filtration rate <60 ml/min/1.73…
- Conditions
- Cardiovascular Disease, Chronic Kidney Disease, Chronic Renal Disease, Hypertension
- Trial name
- NCT01155128
- Testing
- exercise aerobic
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Federal University of Pelotas
Hypertension Secondary to Renal Disease
Treatment of Resistant Hypertension by Renal Sympathetic Denervation in Patients Undergoing Dialysis Therapy
The study is designed to investigate the efficacy of renal nerve denervation in treating drug-resistant hypertension in patients with end stage renal disease.
- Trial name
- TreatDialRDN (NCT01881035)
- Testing
- Renal nerve denervation
- Where
- Finland
- Volunteers
- 6 people
- Sponsor
- Turku University Hospital
Hypertension
Irbesartan in Hypertension
Study objectives: To demonstrate the effect of irbesartan on the regulation of diastolic blood pressure, in case of missing one dose after a period of administration for 6 to 8 weeks To evaluate the safety of irbesartan
- Trial name
- NCT00265967
- Testing
- Irbesartan
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Sanofi
Hypertension
Awareness Development and Usage of mHealth Technology Among Hypertensive Patients in a Rural Community of Bangladesh
To develop awareness, enhance knowledge, attitude and make behavioral changes by using health education and mHealth technology among hypertensive patients in a rural community of Bangladesh, A Randomized Controlled Trial will be…
- Trial name
- NCT03614104
- Testing
- Mobile Health Technology (short message service)
- Where
- Bangladesh
- Volunteers
- 420 people
- Sponsor
- Hiroshima University
Hypertension, Cardiovascular Diseases
A Cohort Study on Biomarkers of Hypertension in Guangdong Province(GDP Study)
Hypertension is the most common chronic diseases and a most important risk factor for cardiovascular and cerebrovascular diseases, and also a substantial public health problem.
- Trial name
- NCT04212455
- Testing
- Non-interventional study
- Where
- 2 sites in China
- Volunteers
- 50,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Patients Undergoing Neurosurgery
The Comparison of Hypotension Incidence Between Remimazolam and Propofol in Hypertensive Patients Undergoing Neurosurgery
This study aims to find an excellent drug in terms of hemodynamic stability when comparing the propofol and remifentanil with the combined use of remimazolam and remifentanil.
- Trial name
- NCT05164146
- Testing
- propofol, remimazolam
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Ocular Hypertension Glaucoma
Efficacy and Safety Assessment of T4030 Eye Drops Versus Ganfort® UD in Ocular Hypertensive or Glaucomatous Patients.
To demonstrate the non-inferiority of T4030 unpreserved eye drops compared to Ganfort® UD in terms of efficacy.
- Trial name
- NCT04898387
- Testing
- Bimatoprost Timolol (T4030), Bimatoprost Timolol (Ganfort)
- Where
- Bulgaria
- Volunteers
- 554 people
- Sponsor
- Laboratoires Thea
Hypertension
A Study to Evaluate Whether Losartan Protects the Kidney in Hypertensive Diabetic Participants With Microalbuminuria (MK0954-365 AM1)
This study will evaluate whether losartan protects the kidney in hypertensive Type II diabetic participants with microalbuminuria.
- Trial name
- NCT01390415
- Volunteers
- 136 people
- Sponsor
- Organon and Co
Hypertension
Open-label Follow-up Trial of Fixed Dose Combination of Telmisartan + Hydrochlorothiazide in Hypertensive Patients
The primary objective is to assess the efficacy and safety of the fixed dose combination of telmisartan 80 mg + hydrochlorothiazide 25 mg (T80/H25) alone or in addition to other antihypertensive therapies during open-label…
- Trial name
- NCT00267943
- Testing
- telmisartan 80 mg + hydrochlorothiazide 25 mg
- Where
- 78 sites in Denmark, Finland and 14 more
- Volunteers
- 639 people
- Sponsor
- Boehringer Ingelheim
Macular Edema
Macular Thickness and Visual Acuity in Diabetic Hypertensive Patients
In this study, measurements of central macular thickness using optical coherence tomography along with examination of visual acuity by Snellen's chart in diabetic hypertensive patients will be done .
- Trial name
- NCT05209971
- Volunteers
- 100 people
- Sponsor
- Sohag University
Cardiovascular Mortality
Factors Influencing Cardiovascular Prognosis
The purpose of this study is to identify risks for cardiovascular events in a follow up period of 10 years.
- Trial name
- Pythia-GR (NCT00973206)
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Hypertension
I PREVENT - Irbesartan In Hypertensive Diabetic Patients
To evaluate Blood Pressure (BP) reduction to the targeted values (Systolic BP ≤ 130 mmHg and Diastolic BP ≤ 80 mmHg) in hypertensive type 2 diabetic patients.
- Trial name
- NCT00362258
- Testing
- Irbesartan (Aprovel)
- Where
- Egypt
- Volunteers
- 797 people
- Sponsor
- Sanofi
Hypertension
Open-label inteRventional Clinical Trial to Assess Efficacy and Safety of the exteMporaneous combInation of Nebivolol and Ramipril in hypertenSIve pAtients
Open-label, inteRventional clinical Trial to assess EffIcacy and safety of the exteMporaneous combInation of Nebivolol and Ramipril in hypertenSIve pAtients.
- Trial name
- ARTEMISIA (NCT06104423)
- Testing
- Nebivolol 5 mg, Ramipril 2.5/5/10 mg
- Where
- Hungary
- Volunteers
- 266 people
- Sponsor
- Menarini International Operations Luxembourg SA