Clinical trials: Hypertensive Patients
Sacubitril/Valsartan, Hypertension
Effect of Sacubitril/Valsartan on Cardiac Function in Hypertensive Patients Stratified by BMI: A Real World Study
The purpose of this study is to investigate the effect of sacubitril/valsartan on cardiac function assessed by cardiac magnetic resonance (CMR) in hypertensive patients stratified by BMI.
- Conditions
- Sacubitril/Valsartan, Hypertension, Obesity
- Trial name
- NCT05498675
- Testing
- Sacubitril / Valsartan Oral Tablet [Entresto], ACEI/ARB
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Friendship Hospital
Hypertension With Renal Dysfunction
Safety and Tolerability and Efficacy of LCZ696 in Japanese Hypertensive Patients With Renal Dysfunction
This study assessed the safety, tolerability, and efficacy of LCZ696 in hypertensive patients with renal dysfunction.
- Trial name
- NCT01593787
- Testing
- LCZ696
- Where
- 13 sites in Japan
- Volunteers
- 32 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension, Medication Adherence
Medication Adherence Program
Randomized controlled trial testing the efficacy of the Supporting Tailored Adaptive change and Reinforcement for Medication Adherence Program (STAR-MAP), a health coaching approach that aims to improve antihypertensive…
- Conditions
- Hypertension, Medication Adherence, Behavior and Behavior Mechanisms
- Trial name
- MAP (NCT05183763)
- Testing
- STAR-MAP health coaching, Medication reminder tools
- Where
- 5 sites in United States
- Volunteers
- 402 people
- Sponsor
- Tulane University
Venous Thromboembolism, Pulmonary Embolism
Timing of Venous Thromboembolism Prophylaxis in Patients With Hypertensive Intracerebral Hemorrhage
The objective of this randomized clinical trial is to evaluate the safety and efficiency of different anticoagulation schemes with heparin for venous thromboembolism prevention in patients with hypertensive intracerebral…
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, Intracerebral Hemorrhage, Deep Vein Thrombosis
- Trial name
- NCT06753786
- Testing
- Venous thromboembolism prophylaxis with unfractionated heparin or low molecular weight heparin starting within the first 2 days but not earlier than 12 hours after a hospital admission., Venous thromboembolism prophylaxis with unfractionated heparin or low molecular weight heparin starting on the 3rd day after a hospital admission.
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Pirogov Russian National Research Medical University
Atrial Fibrillation Recurrent, Hypertension
Sacubitril Valsartan in Preventing the Recurrence of Atrial Fibrillation After Ablation in Elderly Hypertensive Patients With Atrial Fibrillation
Study name: Sacubitril Valsartan in Preventing the Recurrence of Atrial Fibrillation After Ablation in Elderly Hypertensive Patients With Atrial Fibrillation. Medicine: sacubitril/valsartan (100mg) and valsartan (80mg).
- Trial name
- NCT05528419
- Testing
- Sacubitril-valsartan, Valsartan
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Enalapril Adverse Reaction, Pharmacogenomics
A Pharmacogenomics Study of Safety and Efficacy of Enalapril or Enalapril-Folic Acid Therapy in Hypertensive Patients.
Dry cough is the most common adverse reaction of angiotensin converting enzyme, including enalapril, in Chinese population. Clinical observations suggest that the incidence of ACEI-induced dry cough is different between Chinese…
- Conditions
- Enalapril Adverse Reaction, Pharmacogenomics, Stroke
- Trial name
- NCT03259399
- Testing
- detection of genotype
- Where
- China
- Volunteers
- 2,200 people
- Sponsor
- Cui Yimin
Elderly, Hypertension
Unsupervised Physical Activity in Elderly
To evaluate safety and the effects of a unsupervised physical activity program (USPAP) over blood pressure (BP), physical fitness (PF) and quality of life (QL) of elderly hypertensive patients.
- Conditions
- Elderly, Hypertension, Physical Conditioning
- Trial name
- NCT02976506
- Testing
- Unsupervised exercise program, Physical fitness and quality of life
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Lignocaine, Hypertensive Patients
Preoperative Nebulized Lignocaine Versus Nebulized Dexmedetomidine for Blunting the Pressor Response to Laryngoscopy and Intubation in Controlled Hypertensive Patients
This study aims to compare the efficacy of preoperative nebulized lignocaine versus nebulized dexmedetomidine for blunting the pressor response to laryngoscopy and intubation in patients with controlled hypertension under medical…
- Conditions
- Lignocaine, Hypertensive Patients, Dexmedetomidine, Laryngoscopy
- Trial name
- NCT07897578
- Testing
- Group D (Dexmedetomidine), Group L (Lignocaine)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Hypertension, Insulin Resistance
Effects of Pioglitazone in Hypertensive Patients
Insulin resistance is often complicated with hypertension. AGE and inflammation play important roles in insulin resistance. Some studies reported that pioglitazone, insulin sensitizer, is effective for patients with insulin…
- Trial name
- NCT01472497
- Testing
- Pioglitazone
- Where
- Japan
- Volunteers
- 16 people
- Sponsor
- Tottori University Hospital
Hypertension
The Effect of Smart Phone Application Supported Nursing Care Program
Hypertension is an important public health problem in our country and in the world. For success in hypertension treatment, timely and accurate diagnosis of patients, effective implementation of lifestyle changes, timely…
- Trial name
- NCT05392140
- Testing
- Health belief model-based smartphone-assisted nursing care program application will be installed on the phones of the patients who will be in the intervention group., Standart care
- Volunteers
- 102 people
- Sponsor
- Kastamonu University
Congenital Heart Disease
Reversibility by Sildenafil of Exercise-Induced Abnormal Right Ventricular Pressure Response in ASD and VSD-Operated Patients
The purpose of this study is to determine whether oral sildenafil citrate reduces the abnormal right ventricular pressure response during exercise in adolescent and adult patients with specific types of congenital heart defects.
- Trial name
- NCT00772135
- Testing
- sildenafil citrate
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Hypertension
Effect of the Angiotensin II Receptor Antagonist Irbesartan on Biochemical and Functional Markers of Endothelial Dysfunction in Patients With Hypertension
Primary: To evaluate the impact of irbesartan on endothelial function in hypertensive patients with metabolic syndrome. Secondary: To evaluate the oxidative stress status in patients with hypertension with metabolic syndrome.
- Trial name
- NCT00529750
- Testing
- IRBESARTAN, Atenolol
- Volunteers
- 108 people
- Sponsor
- Sanofi
Kidney Injury, Acute, Cardiac Function Failed
Effect of Vasopressin on Kidney and Cardiac Function in Septic Shock
Septic shock is a syndrome characterized by tissue hypoperfusion and hypotension secondary to an uncontrolled infection. It is a frequent cause of admission to the intensive care unit (ICU) and has an associated mortality around…
- Trial name
- NCT06125184
- Testing
- Vasopressor test
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Hypertension
A Study to Determine the Effectiveness and Tolerability of MK8141 in Patients With High Blood Pressure (MK-8141-006)
This study will evaluate the effectiveness and tolerability of MK8141 in lowering blood pressure in patients who have hypertension (high blood pressure).
- Trial name
- NCT00543413
- Testing
- MK8141, Enalapril
- Volunteers
- 160 people
- Sponsor
- Merck Sharp & Dohme LLC
Hypertension
A Clinical Trial to Evaluate the Blood Pressure Lowering Effect of a Candemore Plus Tab Versus Cantabell Tab in Hypertensive Patients Inadequately Controlled by Candesartan Monotherapy
Phase 4 clinical trial to Evaluate the blood pressure lowering effect of a Candesartan/Hydrochlorothiazide(Candemore Plus Tab) versus Candesartan/Amlodipine(Cantabell Tab) in Hypertensive Patients
- Trial name
- NCT04521023
- Testing
- Cantabell Tab, Candemore Plus Tab
- Where
- 14 sites in South Korea
- Volunteers
- 132 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Metabolic Syndrome
A Clinical Trial of YMC017 in Hypertensive and Hypercholesterolemic Patients With Metabolic Syndrome
This is a Randomized, open-label, 2 groups, parallel design.
- Trial name
- NCT02968160
- Testing
- Telmisartan 40mg + Rosuvastatin 20mg, Telmisartan 80mg + Rosuvastatin 20mg, Telmisartan 40mg, 80 mg
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Yuhan Corporation
Hypertension
Diet and Other Non Pharmacological Interventions to Reduce Cardiovascular Risk in Hypertensive Patients
The purpose of this study is to evaluate the effectiveness of diet change and other non-pharmacological treatments which includes physical activity and integrative therapies oriented to reduce the blood pressure in hypertensive…
- Trial name
- NCT04746118
- Testing
- DIET CHANGE, PHYSICAL ACTIVITY, INTEGRATIVE PRACTICES
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Hospital Universitário Clementino Fraga Filho
Hypertension, Hypertension,Essential
Effects of Electrical Nervous Stimulation Transcutaneous in Hypertensive Patients
Systemic arterial hypertension is a disease characterized by high blood pressure levels. It has a high prevalence, is a precursor of cardiovascular diseases, resulting in high costs to the health system and increased mortality.
- Trial name
- NCT06025643
- Testing
- TENS - Cervical stimulation group, TENS - Plus cervical stimulation group, TENS - Renal stimulation group
- Volunteers
- 40 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Hypertension
Comparison of Bisoprolol With Metoprolol Succinate Sustained-release on Heart Rate and Blood Pressure in Hypertensive Patients
This is a multicentre, randomized, open-label parallel trial to demonstrate the superiority and/or non-inferiority of bisoprolol on metoprolol succinate sustained-release (SR) tablet in subjects with mild to moderate primary…
- Trial name
- CREATIVE (NCT01508325)
- Testing
- Bisoprolol, Metoprolol
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Hypertension, Type 2 Diabetes Mellitus
Study of the Glycemic Effects of Nebivolol Compared With Metoprolol and HCTZ in Diabetic Hypertensive Patients
This study will evaluate the effects of nebivolol on glycemic control compared with metoprolol and HCTZ in patients with hypertension and type 2 diabetes mellitus
- Trial name
- NCT00744237
- Testing
- Nebivolol, Metoprolol ER, HCTZ
- Where
- 65 sites in United States, Puerto Rico
- Volunteers
- 231 people
- Sponsor
- Forest Laboratories