Clinical trials: Hypertensive Patients
Hypertension
Diet and Other Non Pharmacological Interventions to Reduce Cardiovascular Risk in Hypertensive Patients
The purpose of this study is to evaluate the effectiveness of diet change and other non-pharmacological treatments which includes physical activity and integrative therapies oriented to reduce the blood pressure in hypertensive…
- Trial name
- NCT04746118
- Testing
- DIET CHANGE, PHYSICAL ACTIVITY, INTEGRATIVE PRACTICES
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Hospital Universitário Clementino Fraga Filho
Diastolic Dysfunction, Hypertension
Impact of HMGB1 on Diastolic Dysfunction in Hypertensive Patients
This study evaluated the association between HMGB1 and diastolic dysfunction in hypertensive patients. HMGB1 level were tested in all patients, and diastolic function determined by echocardiographic.
- Conditions
- Diastolic Dysfunction, Hypertension, Inflammation
- Trial name
- NCT03177408
- Volunteers
- 100 people
- Sponsor
- Jing Li
Hypertension
Whole Body Vibration Training Applied with Different Frequencies in Hypertensive Patients
At least 36 volunteers with a diagnosis of hypertension in the Department of Cardiology of Dokuz Eylul University and who meet the criteria for follow-up and inclusion will participate in the study.
- Trial name
- NCT05768555
- Testing
- Whole body vibration intervention at 40 Hz, Whole body vibration intervention at 25 Hz, Whole body vibration intervention at 0 Hz
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Dokuz Eylul University
Hypertension
Telmisartan Tab Hypertension
To assess the efficacy of telmisartan in hypertensive patients with high cardiovascular risk
- Trial name
- NCT00890084
- Testing
- Telmisartan or Telmisartan + Hydrochlorothiazide (HCTZ)
- Volunteers
- 2,913 people
- Sponsor
- Boehringer Ingelheim
Hypertension, Left Ventricular Diastolic Dysfunction
Sacubitril/Valsartan Versus Valsartan Alone on Left Atrial Volume Index in Hypertensive Patients
Hypertension is a leading global risk factor for cardiovascular disease and is frequently associated with left atrial and ventricular remodeling, leading to subclinical diastolic dysfunction[cite: 2].
- Conditions
- Hypertension, Left Ventricular Diastolic Dysfunction, Essential (Primary) Hypertension
- Trial name
- NCT07853625
- Testing
- Sacubitril / Valsartan, Valsartan
- Volunteers
- 102 people
- Sponsor
- University of Health Sciences Lahore
Cerebral Hemorrhage, Intracranial Arteriovenous Malformations
MRI for the Early Evaluation of Acute Intracerebral Hemorrhage
What happens in the borderzone of a cerebral hemorrhage remains widely onknown and furhter the best timing for doing MR to look for vascular pathology in cerebral hemorrhage has not yet been determined.
- Conditions
- Cerebral Hemorrhage, Intracranial Arteriovenous Malformations, Intracranial Hemorrhage, Hypertensive, Brain Neoplasms
- Trial name
- NCT01689402
- Testing
- MRI Scan with the specified sequences below:
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Bispebjerg Hospital
Hypertension
Study 2: Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients
Hypertension (HTN) is the single most prevalent risk factor for cardiovascular disease, diabetes, obesity and metabolic syndrome.
- Trial name
- NCT02133885
- Testing
- Minocycline Group
- Where
- United States
- Sponsor
- University of Florida
Hypercholesterolemia, Hypertension
Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patients
In this study, Amlodipine has been used to study its effects in newly diagnosed hypertensive patients.
- Conditions
- Hypercholesterolemia, Hypertension, Cholesterol Deposition
- Trial name
- NCT05467384
- Testing
- Amlodipine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ayub Teaching Hospital
Hypertension
A Study of Safety and Efficacy in MK-0954A Combination in Participants With Hypertension (MK-0954A-373 AM3)
This study is being conducted to evaluate the safety and antihypertensive efficacy of MK-0954A (Losartan 50 mg / Hydrochlorothiazide (HCTZ) 12.5 mg) in participants with mild to moderate essential hypertension.
- Trial name
- NCT01431508
- Testing
- Losartan 50 mg / HCTZ 12.5 mg
- Volunteers
- 15 people
- Sponsor
- Organon and Co
Hypertension
Comparison of Nebivolol and Metoprolol With Exercise and Angiotensin II in Hypertensive Patients
The purpose of this study is to determine if Nebivolol a) attenuates the angiotensin II (Ang II)-induced increase in oxidative stress, thereby attenuating Ang II-induced vasoconstriction; and b) attenuates sympathetic mediated…
- Trial name
- NCT01502787
- Testing
- Metoprolol succinate, Nebivolol, Forearm blood flow
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Texas Southwestern Medical Center
Essential Hypertension
Hydrochlorothiazide (+) Losartan Potassium vs. Amlodipine Comparative Study (0954A-314)
An efficacy and safety study of hydrochlorothiazide (+) losartan potassium compared to amlodipine at week 12 in Korean patients with essential hypertension
- Trial name
- NCT00157963
- Testing
- MK0954A; hydrochlorothiazide (+) losartan potassium / Duration of Treatment: 12 weeks
- Volunteers
- 174 people
- Sponsor
- Organon and Co
Hypertension
Effect Of Carvedilol Versus Metoprolol On Glycemic Control In Patients With Type II Diabetes And Hypertension
Evaluation of the effect of two different antihypertensive treatments on control of glucose in Type II diabetic patients with high blood pressure
- Trial name
- NCT00060931
- Testing
- carvedilol, metoprolol
- Where
- 119 sites in United States
- Volunteers
- 501 people
- Sponsor
- GlaxoSmithKline
Severe Trauma Brain Injury, Intracranial Hypertension
Sodium-Lactate and Traumatic Brain Injury
The purpose of this study is to compare the effect of bolus of either sodium-lactate or mannitol on the evolution of intracranial pressure (ICP) during intracranial hypertensive episodes (IHE)
- Trial name
- NCT00319345
- Testing
- Mannitol, Sodium-Lactate
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Institut d'Anesthesiologie des Alpes Maritimes
Arterial Hypertension, Medication Nonadherence
Feasibility of a Program on a Nurse-led Telephone 6-month-follow-up for Uncontrolled Hypertensive Women
This study evaluate the feasibility of a 6-month personalized support program for hypertensive and non-observant women, led by nurses by telephone follow-up.
- Trial name
- PreDynamiques (NCT03963934)
- Testing
- Program on a nurse-led telephone 6-month-follow-up for uncontrolled hypertensive women: a patient-tailored intervention
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Mme Edith DAUCHY
Hypertension
Tadalafil Effects in Left Ventricle Diastolic Dysfunction in Resistant Hypertensive Patients
Left ventricle diastolic dysfunction (LVDD) is associated with resistant hypertension. In addition, brain natriuretic peptide (BNP) levels are elevated when LVDD is present.
- Trial name
- NCT01743911
- Testing
- sugar pill, Tadalafil
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Campinas, Brazil
Hypertension; Heart Disease, Hypertensive
Effect of Blood Pressure on Myocardial Work in Patients With Hypertension
Hypertension is a serious threat to human health and a major global economic burden. Chronic hypertension can cause left ventricular remodeling and loss of function, eventually leading to heart failure.
- Trial name
- NCT05062811
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chongqing Medical University
Hypertension, Dyslipidemia
Effect of Omega 3 in Hypertensive Patients
This study aims to evaluate the impact of omega-3 (O3) supplementation in participants with high blood pressure and elevated triglycerides, focusing on cardiovascular risk factors.
- Trial name
- OMECARDIO (NCT06840964)
- Testing
- omega 3 ethyl esters at 90%
- Where
- Argentina
- Volunteers
- 100 people
- Sponsor
- Santa Maria de la Salud, Argentina
Hypertension
Irbesartan/Amlodipine in Hypertensive Patients Uncontrolled on Amlodipine 5 mg Monotherapy
Primary Objective: To demonstrate that the antihypertensive efficacy of the fixed combination irbesartan/amlodipine 150/5 mg is superior to that of amlodipine 5 mg monotherapy in lowering systolic blood pressure (SBP) as measured…
- Trial name
- I-COMBINE (NCT00956644)
- Testing
- irbesartan/amlodipine, amlodipine
- Where
- 40 sites in Brazil, Chile and 7 more
- Volunteers
- 406 people
- Sponsor
- Sanofi
Metabolic Syndrome, Hypertension
Irbesartan in the Treatment of Hypertensive Patients With Metabolic Syndrome
The purpose of this clinical research study is to learn if irbesartan is superior to hydrochlorothiazide relative to effects on insulin sensitivity and glucose metabolism in hypertensive patients with metabolic syndrome.
- Trial name
- NCT00110422
- Testing
- Irbesartan, Hydrochlorothiazide
- Where
- 25 sites in France, Germany and 4 more
- Volunteers
- 400 people
- Sponsor
- Bristol-Myers Squibb
Type 2 Diabetes Mellitus, Hypertension
Evaluation of Improved Outcomes Among Ambulatory Diabetes and/or Hypertensive Patients - an Intervention Study (CPCLINT)
The goal of this interventional study is to compare improved outcomes among diabetes and/or hypertensive patients sequel to educational intervention.
- Trial name
- CPCLINT (NCT05996601)
- Testing
- Educational intervention
- Where
- Nigeria
- Volunteers
- 400 people
- Sponsor
- University of Ibadan