Clinical trials: Hypertensive Patients
Root Caries, Antihypertensive Drugs
Effect of Hypertensive Drugs on Root Caries Among Senior Patients in Cairo University
The aim of this analytical cross-sectional study study is to evaluate the prevalence of root caries in senior patients of both genders age of 50 to 70 years old, taking antihypertensive drugs attending the Cairo University Dental…
- Trial name
- NCT06709352
- Testing
- non
- Where
- Egypt
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes Mellitus, Hypertension
Phase 4 Study of the Efficacy of Losartan Based Therapy in Hypertensives With and Without Diabetes
To study antihypertensive efficacy of 12 weeks of Losartan based therapy Resilo (Losartan) and Resilo-H (Losartan+ Hydrochlorothiazide) in uncontrolled hypertensive and diabetic hypertensive patients.
- Trial name
- NCT03978884
- Testing
- Losartan 50Mg Tab, Losartan/Hydrochlorothiazide 50 Mg-12.5 Mg ORAL TABLET, Losartan/Hydrochlorothiazide 100 Mg-25 Mg ORAL TABLET
- Where
- Jamaica
- Sponsor
- The University of The West Indies
Hypertension
High-Dose Quinapril Versus Low-Dose Quinapril Plus Amlodipine in the Treatment of High-Risk Hypertensive Patients
The purpose of this study is to compare the impact of two blood pressure lowering treatments (high dose quinapril versus low dose quinapril plus amlodipine) on variations in heart rate over 24 hours.
- Trial name
- NCT00313547
- Testing
- Quinapril 40 mg, Quinapril 10 mg and amlodipine 5 mg
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Montreal Heart Institute
Primary Hypertension
Effects of Telmisartan/Hydrochlorothiazide Treatment in Hypertensive Patients Under Real-life Setting
One of the most common adverse effects resulting from the therapy with thiazides, thiazide-like diuretics and loop diuretics is increased potassium secretion.
- Trial name
- POTASSIUM (NCT01392534)
- Testing
- Telmisartan/hydrochlorothiazide (Pritor Plus, BAY98-7103)
- Where
- Poland
- Volunteers
- 1,586 people
- Sponsor
- Bayer
Hypertension
Safety and Efficacy of Valsartan and Amlodipine Combined and Alone in Patients With Hypertension.
This trial will compare valsartan and amlodipine combination therapies to both valsartan and amlodipine, and placebo for the treatment of hypertension.
- Trial name
- NCT00409760
- Testing
- valsartan+amlodipine combination, valsartan, amlodipine
- Where
- Germany
- Volunteers
- 1,930 people
- Sponsor
- Novartis
Portal Hypertension, Hepatic Encephalopathy
Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis
OBJECTIVES: I. Assess the effect of lactulose on the circadian rhythm of plasma melatonin in patients with subclinical hepatic encephalopathy. II.
- Conditions
- Portal Hypertension, Hepatic Encephalopathy, Cirrhosis
- Trial name
- NCT00004796
- Testing
- lactulose
- Volunteers
- 16 people
- Sponsor
- National Center for Research Resources (NCRR)
Hypertension
Irbesartan/Hydrochlorothiazide to Control Elevated Blood Pressure to Target in Moderate to Severe Hypertensive Patients
The primary objective is to evaluate the antihypertensive efficacy of a fixed combination of Irbesartan/HydroChloroThiazide (CoAprovel) in Chinese moderate to severe hypertensive patients.
- Trial name
- NCT00670566
- Testing
- irbesartan/hydrochlorothiazide
- Where
- China
- Volunteers
- 503 people
- Sponsor
- Sanofi
Diabetes Mellitus, Type 2, Hypertension
12 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Patients With Type 2 Diabetes Mellitus
This trial will evaluate safety and efficacy of BI 10773 in hypertensive patients with type 2 diabetes. Since hyperglycaemia and hypertension are key risk factors for both micro- and macrovascular complications, assessment of…
- Trial name
- NCT01370005
- Testing
- BI 10773
- Where
- 120 sites in United States, Canada and 10 more
- Volunteers
- 825 people
- Sponsor
- Boehringer Ingelheim
Hypertension
Predictive Factors of Systolic Dysfunction in Non-complicated Hypertensive Patients
Hypertension is a major cardiovascular risk factor. Heart failure is one of its main complications but the factors that influence its development are still insufficiently known.
- Trial name
- GLOBAL-HTN (NCT02841696)
- Testing
- Cardiac echography
- Where
- France
- Volunteers
- 183 people
- Sponsor
- University Hospital, Bordeaux
Hypertension, Salt; Excess
Intervention for Monitoring of Salt Intake in Hypertensive Patients
Sodium is an essential nutrient for humans, but excessive sodium consumption is causally associated with high blood pressure and increase risk of cardiovascular diseases.
- Trial name
- NCT05397054
- Testing
- Education, Reformulation, Environmental change
- Where
- Thailand
- Volunteers
- 240 people
- Sponsor
- Mahidol University
Atrial Fibrillation
Nifedipine vs Telmisartan on Prevention of Atrial Fibrillation (AF) Recurrence in Hypertensive Patients With AF
Different lowing blood pressure strategies have a different clinical efficacies. Blocking the angiotensin II type 1 receptor (Telmisartan) reduces the incidence of episodes of atrial fibrillation in hypertensive patients with…
- Trial name
- NCT01435161
- Testing
- Nifedipine,, Telmisartan
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
COVID-19 Pneumonia
Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers With Risk of COVID_19
1. To determine the risk of COVID -19 in patients who use ACEI and ARBS 2. To determine the Effect of ACEI and ARBS on COVID -19 infection . 3. To determine the Severity of COVID -19 in patients who use ACEI and ARBS .
- Trial name
- NCT05398731
- Testing
- Covid_19
- Volunteers
- 400 people
- Sponsor
- Assiut University
Hypertension
A Study to Evaluate Whether Losartan Protects the Kidney in Hypertensive Diabetic Participants With Microalbuminuria (MK0954-365 AM1)
This study will evaluate whether losartan protects the kidney in hypertensive Type II diabetic participants with microalbuminuria.
- Trial name
- NCT01390415
- Volunteers
- 136 people
- Sponsor
- Organon and Co
Hypertension
Emerging Biomarkers in Hypertension
First of all to evaluate the relationship between non-conventional biomarkers and essential hypertension; then to evaluate the effects of various anti-hypertensive drugs on blood pressure control and non-conventional biomarkers…
- Trial name
- NCT02064218
- Testing
- Anti-hypertensive drugs
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pavia
Hypertension, Laparoscopic Cholecystectomy
Hemodynamic Stability of Dexmedetomidine in Hypertensive Patients Undergoing Laparoscopic Cholecystectomy
Dexmedetomidine provides better hemodynamic stability to the patients with hypertension undergoing laparoscopic cholecystectomy.
- Trial name
- NCT04646317
- Testing
- Dexmedetomidine injection, Normal Saline
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Dr. Ruth K.M. Pfau Civil Hospital, Karachi
Hypertension (HTN)
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
The purpose of this extension study is to collect additional safety and efficacy on QCZ484 for hypertensive patients who successfully completed the parent study, CQCZ484A12201 or additional QCZ484 studies as specified in the…
- Trial name
- NCT07543120
- Testing
- QCZ484
- Where
- 25 sites in United States, Japan and 1 more
- Volunteers
- 323 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension
Exergaming Training Among Hypertensive Patients
Since Hypertension affects all body systems and importantly postural balance control. So, the evidence indicates a strong link and connection between balance and hypertension through somatosensory, visual, vestibular…
- Trial name
- NCT06777927
- Testing
- Exercise, No intervention
- Where
- Pakistan
- Volunteers
- 81 people
- Sponsor
- Riphah International University
Essential Hypertension
Amlodipine as add-on to Olmesartan in Hypertension
Test the efficacy and safety of the combination of olmesartan and amlodipine in hypertensive patients whose blood pressure is not adequately controlled with olmesartan alone.
- Trial name
- NCT00220220
- Testing
- olmesartan medoxomil, amlodipine
- Where
- 6 sites in Germany
- Volunteers
- 429 people
- Sponsor
- Sankyo Pharma Gmbh
Hypertension, Mhealth
Effect of Digital Intervention on Self-management of Hypertensive Patients at High Risk of Stroke
Stroke is the second leading cause of death in the world, and the number of stroke patients in China ranks the first in the world. Hypertension is the most important risk factor.
- Trial name
- NCT07089810
- Testing
- Digital intervention has a high blood pressure in the high-risk population of stroke Study on the effect of stress on self-management behavior of patients
- Volunteers
- 120 people
- Sponsor
- Affiliated Hospital of Nantong University
Hypertension
A Dose Ranging Study to Compare the Safety and Efficacy of Aliskiren in Patients With High Blood Pressure
This is a study for people diagnosed with hypertension to compare 3 doses (75 mg, 150 mg, and 300 mg) of an experimental product, aliskiren in comparison to a placebo. Each patient is in the study for 8 weeks
- Trial name
- NCT00260923
- Testing
- aliskiren
- Where
- 2 sites in United States, Germany
- Volunteers
- 641 people
- Sponsor
- Novartis