Clinical trials: Hypertensive Patients
Hypertension, Diabetes Mellitus, Type 2
A Study on Ca Blocker Versus AII Antagonists in Hypertension With Type 2 Diabetes
The antihypertensive effect of the increased dose of angiotensin II receptor blocker (AII antagonist) is compared with that of the additional combined use of amlodipine in hypertensive patients with Type 2 diabetes mellitus, who…
- Trial name
- NCT00144144
- Testing
- Angiotensin II receptor antagonists, Calcium channel blocker
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Advanced-J
Hypertension, Sleep Disorder
Phenotypisation of Sleep Pattern in Hypertensive Patients With Non Dipper Pattern
High blood pressure is the most common modifiable risk factor for cardiovascular diseases (CV). The large interindividual variability in clinical expression of the disease and response to treatment, however, makes the management…
- Trial name
- INTO-DIP (NCT06302738)
- Testing
- polysomnography
- Where
- 11 sites in Italy
- Volunteers
- 143 people
- Sponsor
- Istituto Auxologico Italiano
Hypertension,Essential
Hypertension Treatment Adherence Improving Trial
Persistent adherence to lifestyle modifications and blood pressure lowering medications were the best way to control blood pressure.
- Trial name
- NCT04565548
- Testing
- Educational program for hypertensive patients, Usual care
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 148 people
- Sponsor
- The Hong Kong Polytechnic University
Hypertension, Potassium Imbalance
Occurrence of Dyskalemia With Treatment for Hypertension
Hypertension is a major public health issue associated with significant morbidities and mortality. Fixed-dose combination (FDC) pills, combining 2 or more classes of antihypertensive medications have considerable appeal because…
- Trial name
- OK (NCT05155436)
- Testing
- Fixed Dose Combination pill of Telmisartan 40mg and Amlodipine 5 mg
- Where
- Bangladesh
- Volunteers
- 1,090 people, healthy volunteers welcome
- Sponsor
- National Heart Foundation of Bangladesh
Atrial Fibrillation, Atrial Flutter
Prevalence of Primary Aldosteronism in Hypertensive Patients Presenting With Atrial Flutter or Fibrillation
Primary objective of the PAPPHY Study is to establish the prevalence of primary aldosteronism (PA) in consecutive hypertensive patients referred for 'lone' paroxysmal, persistent or permanent atrial flutter or fibrillation (AFF).
- Conditions
- Atrial Fibrillation, Atrial Flutter, Aldosteronism
- Trial name
- PAPPHY (NCT01267747)
- Where
- 2 sites in Italy
- Volunteers
- 411 people
- Sponsor
- University Hospital Padova
Hypertension
Assistance Multidisciplinary in Hypertensive Patient: Randomized Clinical Trial
The purpose of this study is to determine if multidisciplinary care improves the health condition of hypertensives.
- Trial name
- MULTIHAS (NCT02230293)
- Testing
- Multidisciplinary assistance, Conventional treatment and follow up
- Where
- Brazil
- Volunteers
- 124 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Hypertension With Hyperlipidemia
Efficacy/Safety of Telmisartan/Amlodipine/Rosuvastatin in Hypertensive Patients With Hyperlipidemia
A Randomized, Double-blind, Multi-center Phase III Clinical Trial to Evaluate the Efficacy and Safety of Telmisartan/Amlodipine and Rosuvastatin Co-administration in Hypertensive Patients with Hyperlipidemia
- Trial name
- NCT03566316
- Testing
- Telmisartan/Amlodipine, Rosuvastatin, Telmisartan
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- IlDong Pharmaceutical Co Ltd
Hypertension
Implementing Evidence Based Treatment of Hypertension
This study examines the use of patient initiated discussions of blood pressure medication in the primary care setting. Additionally, this study examines different levels of patient incentive(s) to initiate discussions with…
- Trial name
- NCT00265538
- Testing
- Patient educational letter to engage provider in hypertension rx discussion, Financial incentive (Arms B and C) and health educator phone call (Arm C)
- Where
- 2 sites in United States
- Volunteers
- 834 people
- Sponsor
- VA Office of Research and Development
Hypertension
Long Term Study of Valsartan and Amlodipine in Patients With Essential Hypertension (Extension to Study CVAA489A1301)
The purpose of this study is to evaluate long-term safety and tolerability of once daily administration of the combination of Valsartan and Amlodipine 80/5 mg for 52 weeks in patients with essential hypertension.
- Trial name
- NCT00446524
- Testing
- Valsartan + Amlodipine besilate
- Where
- Japan
- Volunteers
- 403 people
- Sponsor
- Novartis
Glaucoma, Ocular Hypertension
Long-term Vascular, Functional and Morphological Changes in Glaucoma and Ocular Hypertensive Patients
This is an observational study involving patients with glaucoma, those with ocular hypertension and healthy subjects. The aim of the study is the long term evaluation of functional, vascular and morphological changes in glaucoma…
- Trial name
- Ippocrate (NCT06827535)
- Where
- 5 sites in Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Mario Stirpe
Chronic Kidney Disease
Effect of Valsartan vs Perindopril on HOMA-IR Index in Patients With Chronic Kidney Disease
The purpose of this study is to compare the effect of valsartan and perindopril on HOMA-IR Index in patients with chronic kidney disease.
- Trial name
- NCT02299310
- Testing
- Valsartan, Perindopril
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chinese PLA General Hospital
Hypertension,Essential, Hypertension, Masked
Wearable Blood Pressure Devices to Identify Masked Uncontrolled Hypertension.
Uncontrolled out-of-office blood pressure (BP), measured by either home BP monitoring (HBPM) or ambulatory BP monitoring, has been shown to predict higher cardiovascular risk.
- Trial name
- NCT04863508
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Essential Hypertension
Use of the Combination of Olmesartan and Hydrochlorothiazide in Essential Hypertension
The study will evaluate the blood pressure lowering effects of two different dosages of the combination of olmesartan and hydrochlorothiazide in patients with moderate or severe high blood pressure.
- Trial name
- NCT00430508
- Testing
- olmesartan medoxomil (OM)/hydrochlorothiazide (HCTZ) tablets, olmesartan medoxomil/hydrochlorothiazide tablets
- Where
- 55 sites in Bulgaria, Czechia and 5 more
- Volunteers
- 972 people
- Sponsor
- Daiichi Sankyo
Hypertension, Metabolic Syndrome
Effect of Valsartan on Lipid Subfractions in Hypertensive Patients With Metabolic Syndrome
The purpose of this study is to evaluate potential effects of valsartan on lipid subfractions and other parameters in lipid metabolism in patients with essential hypertension and metabolic syndrome.
- Trial name
- NCT00394745
- Testing
- Valsartan
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 45 people
- Sponsor
- Novartis
Hypertension Self-management, Hypertension
Adaptive Intervention Model for Hypertension Self-Management in Rural Areas: A Doctor-Patient Interaction Approach
The aim of this project is to develop and validate an adaptive intervention model to improve self-management behavior in rural hypertensive patients.
- Trial name
- NCT06869031
- Testing
- Standard Interactive Intervention for Hypertension Management, Intensified Interactive Intervention for Hypertension Management
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Yuju Wu
Healthy, Hypercholesterolemia
The Role of Cyclooxygenase Activity in the Endothelial Function of Hypertensive and Hypercholesterolemic Patients
A layer of cells called the endothelium line the walls of blood vessels. These cells produce substances that control the tone of blood vessels and thus control blood flow through the vessel.
- Conditions
- Healthy, Hypercholesterolemia, Hypertension
- Trial name
- NCT00001742
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertension
Comparison of Blood Pressure Lowering Effect Between Fimasartan and Losartan
Comparison of blood pressure lowering effect between Fimasartan and Losartan in the hypertensive patient during night and early morning time
- Trial name
- NCT02958631
- Testing
- Fimasartan, Losartan
- Volunteers
- 40 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Hypertension
A Pilot Study of Changing Medication Adherence In Hypertensive African-American Patients
We will conduct an empirical test of the two intervention approaches under study. Specifically, we seek to determine the potential differential impact of positive affect induction and self affirmation.
- Trial name
- NCT00248937
- Testing
- Positive affect and self-affect induction
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Weill Medical College of Cornell University
Reflexology, Hypertension, Acupressure, Traditional Medicine
Effect of Foot Reflexology on Blood Pressure and Pulse Rate: A Randomized Clinical Trial
Hypertension (HT) has been known for its prominent risk of cardiovascular events. Although there are various pharmacological choices, many patients fail to adhere with them.
- Trial name
- NCT04516005
- Testing
- foot reflexology
- Volunteers
- 94 people
- Sponsor
- Khon Kaen University
Cardiovascular Health
HERE: Health Empowerment and Resources After Pregnancy
This study will examine whether a patient navigation program can help improve long-term heart health among people who experienced high blood pressure disorders during pregnancy at Boston Medical Center (BMC).
- Trial name
- HERE (NCT07701148)
- Testing
- Longitudinal patient navigation, Standard care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston Medical Center