Clinical trials: Hypertensive Patients
Hypertensive Patients With Dyslipidemia
Clinical Trial to Evaluate the Efficacy and Safety of CKD-333 Tablet
To Evaluate the Efficacy and Safety of CKD-333
- Trial name
- NCT03583905
- Testing
- CKD-330, D086, D723
- Where
- 16 sites in South Korea
- Volunteers
- 154 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Obstructive Sleep Apnea, Masked Hypertension
Masked Hypertensive Patients With Obstructive Sleep Apnea
The general objective is to evaluate the effect of continuous positive airway pressure (CPAP) treatment in patients with masked hypertension.
- Trial name
- Masked-OSA (NCT04251975)
- Testing
- CPAP treatment
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Hypertension
Novel Approaches of Advanced Neuroimaging Based on MRI Fiber Tracking to Detect Early Signs of Vascular Cognitive Impairment in Hypertensive Patients
Hypertension is the major risk factor for vascular cognitive impairment (VCI). One of the main limitations in the clinical approach to VCI is that, by the time that it is manifested, it might be too late to reverse the…
- Trial name
- NCT03986957
- Testing
- No interventions
- Where
- Italy
- Volunteers
- 176 people
- Sponsor
- Neuromed IRCCS
High Blood Pressure, Metabolic Syndrome
Comparison of Aliskiren and Amlodipine on Insulin Resistance and Endothelial Dysfunction in Patients With Hypertension and Metabolic Syndrome
The purpose of this study was to determine the effects of Aliskiren on insulin resistance (IR) and endothelial dysfunction (ED) in patients with high blood pressure and metabolic syndrome.
- Conditions
- High Blood Pressure, Metabolic Syndrome, Insulin Resistance, Endothelial Dysfunction
- Trial name
- NCT00417170
- Testing
- Aliskiren, Amlodipine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Novartis Pharmaceuticals
Essential Hypertension, Metabolic Syndrome
A Clinical Trial to Evaluate the Blood Pressure Control of Telmisartan or Losartan in Essential Hypertensive Patients With Metabolic Syndrome
This is a multi-center, randomized, open-label, active comparator-controlled, phase 4 clinical trial to evaluate the blood pressure control of Telmisartan or Losartan in essential hypertensive patients with metabolic syndrome
- Trial name
- PRISTINE (NCT05843162)
- Testing
- Telmisartan, Losartan
- Volunteers
- 116 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertension, Cognitive Decline
Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control in Minimize Cognitive Decline
The study will test a multifaceted strategy for implementing an intensive blood pressure intervention protocol targeting systolic BP <120 mmHg on cognitive decline in racial minority and low-income hypertensive patients in…
- Trial name
- IMPACTS-MIND (NCT04797403)
- Testing
- Stepped-care protocol adapted from the SPRINT intensive-treatment algorithm
- Where
- United States
- Volunteers
- 1,306 people, healthy volunteers welcome
- Sponsor
- Tulane University
Chronic Kidney Disease, Hypertension
Aliskiren and Muscle Sympathetic Nerve Activity
The central hypothesis of this project is that Aliskiren causes a substantial decrease in MSNA in hypertensive patients with CKD.
- Conditions
- Chronic Kidney Disease, Hypertension, Muscle Sympathetic Nerve Activity
- Trial name
- MSNA (NCT00719316)
- Testing
- Aliskiren
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- UMC Utrecht
Cardiovascular Diseases, Surgery
Pressure Recording Analytical Method Parameters and Their Relationship With Hypotension in Hypertensive Patients
Perioperative anesthesiologists can benefit from easily obtainable hemodynamic variables detecting or quantifying the lack of an adequate compensatory capacity of the cardiovascular system in order to optimize patient management…
- Conditions
- Cardiovascular Diseases, Surgery, Hypotension, Hypotension on Induction
- Trial name
- PRAM-in-HYPO (NCT05960604)
- Testing
- Passive leg raising
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 660 people
- Sponsor
- Recep Tayyip Erdogan University
Hypertension
Variability of Sulfotransferase Activity in Humans: an Approach to Improve Predictive Drug Response Part II: Analysis of Interindividual Variation in Hypertensive Patients
An open-label, single center, nonrandomized clinical study in hypertensive patients, with intervention, over a 5-week period. After written informed consent, subjects will undergo screening evaluations, including blood and urine…
- Trial name
- NCT06782204
- Testing
- Paracetamol
- Where
- Portugal
- Volunteers
- 7 people
- Sponsor
- Hospital da Luz, Portugal
Cardiac Rehabilitation, Rheumatoid Arthritis
The Effects of Cardiac Rehabilitation Programme in Hypertensive Rheumatoid Arthritis Patients
The aim of this study is to investigate the beneficial impacts of the 6-week standardized CR program applied to hypertensive RA patients whose disease activity is under control with regular pharmacological treatment.
- Conditions
- Cardiac Rehabilitation, Rheumatoid Arthritis, Hypertension
- Trial name
- CARDIRA (NCT06295848)
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Hypertension
Spironolactone Versus Indapamide in Obese and Hypertensive Patients
Most recent guidelines continue to recommend thiazide diuretics as first-line agents for patients with hypertension in spite of the potential metabolic side effects, while mineralocorticoid receptor antagonists (MRAs), such as…
- Trial name
- NCT03626506
- Testing
- Spironolactone, Indapamide, Amlodipine
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
Atrial Fibrillation Recurrent
SPironolactONe for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation
Introduction: There is evidence that aldosterone and the activation of its receptor, mineralocorticoid receptor (MR), promote cardiac fibrosis and electrical disturbances.
- Trial name
- SPONSoR (NCT06204640)
- Testing
- Spironolactone
- Volunteers
- 580 people
- Sponsor
- University Hospital, Caen
Pressure; Brachial Plexus
The Effect of Remote Ischemic Preconditioning (RIPC) on Blood Pressure and Its Vascular Protection Effect
The purpose of this study is to determine the effect of remote ischemic preconditioning (RIPC) on blood pressure and its vascular protection effect among Chinese young healthy adults and primary hypertensive patients stage I.
- Trial name
- NCT02414997
- Testing
- RIPC
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Chronic Kidney Diseases
Chronic Kidney Disease Among Hypertensive Patients in Ha'il, Saudi Arabia
Chronic kidney disease (CKD) is defined as persistent abnormalities of kidney structure or function for more than 3 months leading to a sustained reduction in glomerular filtration rate (GFR) and/or to the occurrence of kidney…
- Trial name
- CKD (NCT05030480)
- Testing
- renal functions
- Where
- Saudi Arabia
- Volunteers
- 392 people
- Sponsor
- Zagazig University
Glaucoma
Efficacy and Safety of Travoprost 0.004% Versus Tafluprost 0.0015% in Patients With Primary Open-angle Glaucoma or Ocular Hypertension
The purpose of this study is to assess the safety and efficacy of Travoprost 0.004% and Tafluprost 0.0015% in patients with primary open angle glaucoma or ocular hypertension when both medications are administered in the evening.
- Trial name
- NCT00966940
- Testing
- Travoprost 0.004% ophthalmic solution (TRAVATAN), Tafluprost 0.0015% ophthalmic solution
- Volunteers
- 51 people
- Sponsor
- Alcon Research
Limb Ischemia
Comparison of Aspirin Alone Versus Low-Dose Rivaroxaban Plus Aspirin in Chronic Limb-Threatening Ischemia
The goal of this clinical trial is to compare the effectiveness of low-dose rivaroxaban plus aspirin versus aspirin alone in patients aged 40-70 years with chronic limb-threatening ischemia, diabetes mellitus, hypertension, and…
- Trial name
- NCT07832578
- Testing
- Aspirin tablet, Low-Dose Rivaroxaban Plus Aspirin,
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- King Edward Medical University
Hypertension
Study Describing the Hypertensive Population Treated With Telmisartan and Conditions of Use by Medical Practitioners and Patients
Primary objective: to characterize hypertensive patients treated for at least 1 month with Telmisartan (alone or in combination with other drugs) in order to define the beneficiary population (those actually receiving the…
- Trial name
- NCT02242851
- Testing
- Telmisartan
- Volunteers
- 5,018 people
- Sponsor
- Boehringer Ingelheim
Patients Undergoing Neurosurgery
The Comparison of Hypotension Incidence Between Remimazolam and Propofol in Hypertensive Patients Undergoing Neurosurgery
This study aims to find an excellent drug in terms of hemodynamic stability when comparing the propofol and remifentanil with the combined use of remimazolam and remifentanil.
- Trial name
- NCT05164146
- Testing
- propofol, remimazolam
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Infection, Heart Failure
Remote Physician Care for Home Hospital Patients
This study examines the implications of providing remote physician care to home hospitalized patients compared to usual home hospital care with in-person/in-home physician visits.
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT04080570
- Testing
- Remote Visit
- Where
- 2 sites in United States
- Volunteers
- 172 people
- Sponsor
- Brigham and Women's Hospital
Hypertension, Obesity
Trial Comparing Metabolic Effects of Telmisartan and Amlodipine on Hypertensive Patients With Obesity and Diabetes
Recent studies have shown that obese people are more prone to high blood pressure. With the co-existence of obesity, hypertension and diabetes, patients were more susceptible to hyperlipidemia, coronary and cerebral…
- Conditions
- Hypertension, Obesity, Diabetes
- Trial name
- HOT-DM (NCT00847262)
- Testing
- Temisartan, Amlodipine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Third Military Medical University