Clinical trials: Hypertensive Patients
Hypertension, Abdominal Aortic Aneurysm
Study on Anti-inflammatory Effect of Anti-hypertensive Treatment in Patients With Small AAA's and Mild Hypertension
Inflammation of the blood vessel plays an important role in the development and growth of a dilated abdominal aorta. An elevated blood pressure leads to an increase in inflammation, therefore blood pressure lowering is an…
- Trial name
- PISA (NCT01425242)
- Testing
- Aliskiren, Amlodipine
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- Amsterdam UMC, location VUmc
Hypertension,Essential
An OS to Evaluate Effectiveness and Safety of Fixed-dose Combinations of FMS/AML or FMS/AML/HCTZ
The main purpose of this observation study is to collect data on the effects and side effects for 12 weeks of the medication administration of the single-pill combinations, which are fimasartan/amlodipine or…
- Trial name
- NCT05413057
- Where
- South Korea
- Volunteers
- 20,000 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Severe Hypertension
Safety and Tolerability and Efficacy of LCZ696 in Japanese Severe Hypertensive Patients
This study assessed the safety, tolerability, and efficacy of LCZ696 in severe hypertensive Japanese patients
- Trial name
- NCT01646671
- Testing
- LCZ696
- Where
- 9 sites in Japan
- Volunteers
- 35 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension
CKD-828 Telmisartan Non-Responder Trial
The aim of the present study is to evaluate the efficacy and safety of two dose combination of Telmisartan/S-Amlodipine (40/2.5mg and 40/5mg) compared with telmisartan monotherapy (80mg) in hypertensive patients inadequately…
- Trial name
- NCT01426100
- Testing
- CKD-828 40/2.5mg, CKD-828 40/5mg, Telmisartan 80mg
- Where
- 18 sites in South Korea
- Volunteers
- 183 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertensive Leg Ulcer
To Assess Analgesia Provided by Continuous Sciatic Nerve Block in Patients With Hypertensive Leg Ulcer
Hypertensive leg ulcer, also called Martorell ulcer, represents 1 to 15% of leg ulcers in hospital. These ulcers are painful, long to heal, and hospitalization is sometimes necessary for analgesia and debridement of necrotic…
- Trial name
- ANGIOCATH (NCT01964911)
- Testing
- Ropivacaïne
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Nantes University Hospital
Central Blood Pressure in Diabetic Hypertensive
The Effect of Central Blood Pressure on Clinical Outcome in Diabetic Hypertensive Patients in Assiut University Hospitals
In recent decades, some observational studies suggest that peripheral BP measured by brachial artery may not necessarily represent BP measured in the aortic artery which is known as central BP .In addition, some clinical trials…
- Trial name
- NCT03682016
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hypertension
The Effect of a Complementary Multi Disciplinary Program on Blood Pressure in Hypertensive Patients
Intervention description: Complementary Approaches to Lower Mean arterial pressure (CALM) is a multi dispensary program aimed to reduce blood pressure in hypertensive patients.
- Trial name
- NCT00409149
- Testing
- CALM Approache, DASH approach
- Where
- Israel
- Volunteers
- 113 people
- Sponsor
- Assaf-Harofeh Medical Center
Hypertension Complicated, Hypertrophy, Left Ventricular
Efficacy and Safety of Valsartan and Nebivolol/Valsartan in Hypertensive Patients With LVH
To assess the efficacy of Left Ventricular Hypertrophy (LVH) reduction and 24-hour blood pressure control of Valsartan 80mg or Nebivolol/Valsartan 5/80mg once daily as replacement therapy for currently treated or untreated…
- Conditions
- Hypertension Complicated, Hypertrophy, Left Ventricular, Blood Pressure
- Trial name
- BVreduce (NCT03180593)
- Testing
- Valsartan 80 mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Trinity Hypertension & Metabolic Research Institute
Chronic Coronary Syndrome, Hypertension
Benidipine in Hypertensive and/or Chronic Coronary Syndrome Patients
Evaluation of the clinical outcomes of Benidipine initiated by physician's preference in patients with hypertension and/or angina pectoris (chronic coronary syndrome) presenting to cardiology outpatient clinics in Turkey.
- Conditions
- Chronic Coronary Syndrome, Hypertension, Angina Pectoris
- Trial name
- Benidipine-TR (NCT06808321)
- Testing
- Benidipine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 800 people
- Sponsor
- The Society of Prevention and Awareness of Cardiovascular Diseases
Hypertension
An Observational Cohort Study to Evaluate the Safety and Efficacy of Micardis Tablets Taken Once Daily at 40 mg/Day and 80 mg/Day in Hypertensive Patients Under Real Life Conditions in Usual Clinical Practice
The "CONTROL" study is an out patient based prospective observational cohort study. The main aim of the study is to survey the safety and efficacy of Micardis 40 mg/day and 80 mg/day under real life conditions in usual clinical…
- Trial name
- NCT00982735
- Volunteers
- 987 people
- Sponsor
- Boehringer Ingelheim
Diabetes
Preventing Microalbuminuria in Type 2 Diabetes
In people with type 2 diabetes, microalbuminuria is a strong, independent risk factor for diabetic nephropathy and cardiovascular morbidity and mortality.
- Trial name
- VARIETY (NCT00503152)
- Testing
- Benazepril, Valsartan, Benazepril/Valsartan
- Where
- 9 sites in Italy
- Volunteers
- 612 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Hypertension
Effects of Aliskiren/Amlodipine Versus Amlodipine Monotherapy on Ankle-foot Volume in Hypertensive Patients
Comparison between the effect of aliskiren/amlodipine combination with amlodipine monotherapy on ankle-foot volume in hypertensive patients. It will be enrolled male or female outpatients, aged 18-65 years.
- Trial name
- NCT01048047
- Testing
- aliskiren/amlodipine
- Where
- 2 sites in Italy
- Volunteers
- 88 people
- Sponsor
- University of Pavia
Blood Pressure
Newer Versus Older Antihypertensive Agents in African Hypertensive Patients (NOAAH) Trial
The purpose of this study is to compare the blood pressure lowering efficacy of a treatment regimen based on a dihydropyridine calcium-channel blocker combined with an angiotensin II type-1 receptor blocker with the recommended…
- Trial name
- NOAAH (NCT01030458)
- Testing
- amlodipine 5/10 mg per day plus valsartan 160 mg/day, hydrochlorothiazide 6.25 mg/day plus bisoprolol 5/10 mg/day
- Where
- 7 sites in Cameroon, Côte d’Ivoire and 3 more
- Volunteers
- 183 people
- Sponsor
- KU Leuven
Hypertension
Antihypertensive Effect of Simvastatin in Hypertensive Patients
Few trials have investigated the hypotensive effect of the Statins. Most were not specifically aimed at this pleiotropic effect or had methodological problems.
- Trial name
- NCT00704548
- Testing
- Simvastatin 40mg
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypertension
COREG MR Versus TOPROL-XL On The Lipid Profile Of Normolipidemic Or Mildly Dyslipidemic Patients With Hypertension
This study was designed to determine whether treatment with COREG MR is more effective at maintaining a better lipid profile than treatment with TOPROL-XL for hypertension.
- Trial name
- NCT00273052
- Testing
- Carvedilol Phosphate modified release formulation, metoprolol succinate
- Where
- 120 sites in United States, Canada and 1 more
- Volunteers
- 514 people
- Sponsor
- GlaxoSmithKline
Hypertensive Patients, Monotherapy
Analysis of Factors Influencing the Efficacy of Levamlodipine Benzoate and Its Population Pharmacodynamic Modeling
1. Preliminarily explore the correlation factors of differences in the efficacy of levamlodipine besylate in the treatment of hypertension. 2.
- Trial name
- NCT05958524
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Glaucoma, Open-Angle, Ocular Hypertension
24-hour Efficacy and Tolerability of the Tafluprost-timolol Fixed Association Without Preservatives in Glaucomatous or Ocular Hypertensive Patients Already Treated With Latanoprost Preserved With BAK. A Prospective, Open Study of 3 Months Duration.
This is a phase IV, interventional, multi-center, open clinical Trial. Patients will be administered one eye drop of tafluprost/timolol fixed combination at 20:00 (+/- 1 hour), in the treatment of open angle glaucoma and ocular…
- Trial name
- HERO (NCT05299593)
- Testing
- tafluprost/timolol
- Where
- 3 sites in Italy
- Volunteers
- 43 people
- Sponsor
- Fondazione G.B. Bietti, IRCCS
Hemodynamics
Gradual Versus Intermittent Release of Tourniquet Effect on MAP in Hypertensive Patients Undergoing Upper Limb Orthopedic Surgeries
In this clinical trial, the authors will compare two tourniquet deflation techniques and their clinical implications on hemodynamics and acid base parameters in hypertensive orthopedic patients undergoing upper limb surgeries…
- Trial name
- NCT07290504
- Testing
- Tourniquet deflation
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Kasr El Aini Hospital
Diabetes, Hypertensive Disease
Effect of Renin-angiotensin System Blockers on Glomerular Filtration Rate in Patients With Hypertension, Type 2 Diabetes With Normoalbuminuria
Diabetes is the leading cause of chronic kidney disease in developed countries. About 30-40% of patients with type 1 and type 2 diabetes mellitus will develop diabetic nephropathy.
- Trial name
- eGFR (NCT01500590)
- Testing
- Renin-angiotensin system blockers, non-renin angiotensin system blockers
- Where
- China
- Volunteers
- 1,400 people
- Sponsor
- Hospital Authority, Hong Kong
Blood Pressure
Anaerobic Exercises on Cardiac Workload, Peripheral Resistance and Lipid Index Among Grade 1 Hypertensive Young Adults
Impact of resistance exercises on grade I hypertensive patients were monitored on three outcome measures that were blood pressure, peripheral resistance and lipid index after 12 weeks of intervention
- Trial name
- NCT04683523
- Testing
- Exercise
- Where
- Pakistan
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Ziauddin University