Clinical trials: Hypertensive Patients
Hypertension, Chronic Kidney Disease.
Effect of Eplerenone in Elderly Hypertensive Early Stage Chronic Kidney Disease (CKD) Patients
The purpose of this study is to determine whether eplerenone is effective in the treatment of blood pressure, heart function, renal function in elderly hypertensive stage1 (eGFR>=90ml/min/1.73m2) and stage2 (eGFR…
- Trial name
- NCT01302236
- Testing
- Eplerenone
- Sponsor
- Jichi Medical University
Hypertension
National Survey on Hypertension
Describe the clinical characteristics of hypertensive patients aged of 75 years and older seen in general practitioner consultation according to their renal damage
- Trial name
- SERENITE (NCT00804167)
- Where
- 1,291 sites in France
- Volunteers
- 4,500 people
- Sponsor
- AstraZeneca
Hypertension on Chronic Maintenance Hemodialysis
The Pharmacokinetics of Nifedipine Controlled Release Tablets in Hypertensive Patients on Hemodialysis
This is a prospective, open, non-randomized, non-controlled study. 20 patients with hypertension on chronic maintenance hemodialysis will be enrolled in the study.
- Trial name
- PICASSO (NCT01021501)
- Testing
- nifedipine controlled release tablets
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Guangzhou First People's Hospital
Hypertension
A 12-week, Multicentric Study to Evaluate the Safety and Efficacy of Bisoprolol in Filipino Hypertensive Subjects With Diabetes
The aim of this 12-week, multicenter, interventional, prospective, open-label and single-arm study is to evaluate the safety and efficacy of 5 milligram per day (mg/day) and 10 mg/day bisoprolol in Filipino hypertensive subjects…
- Trial name
- NCT01190436
- Testing
- Bisoprolol
- Where
- Philippines
- Volunteers
- 125 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Pregnancy, Maternal Anemia
Better Birth Outcomes Through Technology, Education, and Reporting
This is a pragmatic randomized control trial to evaluate the BETTER intervention compared to standard obstetrical care (control) to determine whether it helps to reduce maternal anemia and other adverse pregnancy outcomes.
- Conditions
- Pregnancy, Maternal Anemia, Pre-Term Birth, Hypertensive Disorders
- Trial name
- BETTER (NCT06261398)
- Testing
- BETTER: motivational interviewing and text messaging, Standard of care
- Where
- 3 sites in United States
- Volunteers
- 550 people
- Sponsor
- Ohio State University
Hypertension
VALERIA: Valsartan in Combination With Lisinopril in Hypertensive Patients With Microalbuminuria
The purpose of this study is to compare if the combination of valsartan 320 mg/lisinopril 20 mg versus the monotherapies of lisinopril 40 mg or valsartan 320 mg will result in a greater decrease of urinary albumin excretion…
- Trial name
- NCT00171067
- Testing
- valsartan, lisinopril
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 134 people
- Sponsor
- Novartis
Tracheal Intubation Morbidity, Laryngoscopy
Oral Melatonin VS Nebulized Dexmedetomidine Premedication on Attenuation of Hemodynamic Response to Direct Laryngoscopy and Tracheal Intubation in Hypertensive Patients
The aim of this study is to compare the efficacy of oral melatonin versus nebulized dexmedetomidine in attenuating the hemodynamic response to direct laryngoscopy and endotracheal intubation in controlled hypertensive patients…
- Conditions
- Tracheal Intubation Morbidity, Laryngoscopy, Hemodynamic Response
- Trial name
- NCT06935292
- Testing
- Dexmedetomidine, Melatonin
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Hypertension
Phase III Clinical Study to Evaluate the Efficacy and Safety of the Combination of Lercanidipine/Valsartan in Hypertensive Patients
This study aims to compare and assess the efficacy and the safety of the combination agent of Lercanidipine and Valsartan and monotherapy of Lercanidipine alone in patients with essential hypertension
- Trial name
- NCT01928628
- Testing
- Lercanidipine 10mg, Lercanidipine10mg /Valsartan 80mg, Lercanidipine 10mg /Valsartan 160mg
- Where
- South Korea
- Volunteers
- 449 people
- Sponsor
- LG Life Sciences
Hypertension
Salt Intake, Microbiota, Immune Response and Endothelial Function in Hypertension
Hypertension is a significant cardiovascular risk factor which affects 45% of the adult population. Salt intake is essential in the development and progression of hypertension.
- Trial name
- NCT04648592
- Testing
- Low salt diet plus sodium chloride supplements
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Hypertension, Adherence, Medication
OUTREACH: Urine Analysis and Antihypertensive Treatment
Non-adherence to antihypertensive treatment is one of the leading causes of suboptimal blood pressure control and translates into increased risk of cardiovascular morbidity and mortality.
- Trial name
- OUTREACH (NCT03293147)
- Testing
- HPLC-MS/MS-guided intervention, Standard care
- Where
- 12 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Manchester
Hypertension
An Observation Study on the Identification of Prescription Patterns of Lodient Tab(Telmisartan/S-amlodipine)
This study identify prescription patterns of Lodient Tab and evaluate the changes of the hypertension symptoms (BP pressure) who are first prescribed and taking Lodient Tab.
- Trial name
- NCT06214832
- Where
- South Korea
- Volunteers
- 4,000 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Hypertension
ConfidenHT System for Diagnostic Electrical Mapping of Renal Nerves
To evaluate the safety and performance of the ConfidenHT System
- Trial name
- RDN (NCT02777216)
- Testing
- ConfidenHT system
- Where
- 3 sites in Greece, Netherlands
- Volunteers
- 20 people
- Sponsor
- BlueWind Medical
End-stage Renal Disease
Effects of Strict Volume Control in Hypertensive Hemodialysis Patients on Cardiac Structure and Chronic Inflammation
This study aims mainly to investigate the effects of two approaches to control blood pressure in hypertensive hemodialysis patients; using antihypertensive drugs versus strict volume control (by strict dietary salt restriction…
- Trial name
- NCT00307463
- Testing
- strict volume control policy, antihypertensive drugs administration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 258 people
- Sponsor
- Ege University
Hypertension, Grade 1, Hypertension Treatment
Hypertensive Ambulatory Trial to Compare the Efficacy of HCTZ and Lisinopril
The purpose of this trial is to evaluate if an objective clinical decision of anti-hypertensive therapy can be made using an N-of-1 (single patient) trial design.
- Conditions
- Hypertension, Grade 1, Hypertension Treatment, N of 1 Study Design, Hypertension
- Trial name
- 1HAT (NCT01258764)
- Testing
- Lisinopril, Hydrochlorothiazide
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Scripps Translational Science Institute
Hypertension
Short Term Effect of Empagliflozin in Hypertension
The investigators assessed the 6-week effect of once daily 25mg SGLT2-i Empagliflozin on left ventricular diastolic function and blood pressure profile in non diabetic hypertensive patients
- Trial name
- EMPHYT (NCT04203914)
- Testing
- Empagliflozin Tablets
- Where
- 2 sites in Cameroon
- Volunteers
- 15 people
- Sponsor
- Yaounde Central Hospital
Hypertensive Patients
A Comparative Study of Glidescope Versus Macintosh Laryngoscope in Adult Hypertensive Patients
Hemodynamic response to laryngoscopy and tracheal intubation remain of utmost concern in anesthesia practice. Sympathetic stimulation and adverse physiologic events could be tolerated by healthy individuals, but they may be…
- Trial name
- NCT03316443
- Testing
- Glidescope, Macintosh
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Hypertension, Renal Denervation
The Predictive Role of Proteomics in Blood Pressure Response of Hypertensive Patients Undergoing Renal Denervation.
Renal sympathetic nervous activity plays a crucial role in the development and maintenance of hypertension (HTN). Renal denervation (RDN) is a minimally invasive catheter-based treatment using mainly radiofrequency or ultrasound…
- Conditions
- Hypertension, Renal Denervation, Proteomics
- Trial name
- PREDICT-RDN (NCT06208501)
- Testing
- Urine sample for proteomic analysis, ABPM, OBPM
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Hippocration General Hospital
Hypertension
Efficacy of a Telmisartan/S-Amlodipine on 24-hour BP Control in Hypertensive Patients Inadequately Controlled
To Evaluate the Efficacy of the Timing of the Administration of a Telmisartan/S-Amlodipine (Telminuvo®Tab. 40/2.5mg) on 24-hour BP Control in Hypertensive Patients Inadequately Controlled by Telmisartan Monotherapy
- Trial name
- NCT02526875
- Testing
- Telminuvo®Tab. 40/2.5mg
- Where
- 10 sites in South Korea
- Volunteers
- 208 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertension
Oral Cannabidiol Effect on Blood Pressure in Hypertensive Patients
The objective of this randomized, placebo-controlled and crossover study is to extend the findings from the acute studies into more chronic administration of CBD in individuals with mild or moderate hypertension who are either…
- Trial name
- HYPER-H21-4 (NCT05346562)
- Testing
- Cannabidiol
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- University of Split, School of Medicine
Hypertension,Nephropathy
Nighttime Losartan in Continous Ambulatory Peritoneal Dialysis (NVCAPD)
Hypertension is one of the most important independent risk factors for the prognosis of continous ambulatory peritoneal dialysis patients. The incident rate is high and the control rate is low.
- Trial name
- NCT03692013
- Testing
- Losartan
- Volunteers
- 68 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University