Clinical trials: Hypertensive Patients
Hypertension
Examining the Individual Response to a Restricted Sodium Diet in Hypertensive Patients
Excessive dietary sodium intake is an independent risk factor for hypertension and cardiovascular disease. A vast array of efforts have tried to reduce sodium consumption based on evidence indicating a public health benefit.
- Trial name
- NCT04764253
- Testing
- Modified Sodium Watcher Program + Digital Self-Monitoring, Usual care + Digital Self-Monitoring
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Hypertension
A Study on the Long-term Efficacy of Nebivolol After Withdrawal of Therapy
This study will evaluate the long-term efficacy of nebivolol monotherapy in patients with stage 1 or stage 2 hypertension after the withdrawal of active medication.
- Trial name
- NCT00785512
- Testing
- Nebivolol
- Where
- 26 sites in United States
- Volunteers
- 207 people
- Sponsor
- Forest Laboratories
Hypertension, Microalbuminuria
Community-based Microalbuminuria Screening in Patients With Hypertension
This study evaluates the effectiveness of different anti-hypertensive drugs on patients with hypertension and microalbuminuria.
- Trial name
- CMSIH (NCT03596840)
- Volunteers
- 3,000 people
- Sponsor
- Shanghai Zhongshan Hospital
Hypertension
Canadian Study of Trandolapril on Blood Pressure in Hypertensive Patients
The in-MAU-tion study is conducted to determine the percentage of hypertensive participants with or without diabetes reaching CHEP (Canadian Hypertension Education Program) defined blood pressure targets.
- Trial name
- in-MAU-tion (NCT01078584)
- Where
- 568 sites in Canada
- Volunteers
- 7,993 people
- Sponsor
- Abbott
Hypertension
Cognitive Dysfunction in Hypertensive Patients Having Spine Surgery
While hypotension during general anesthesia has routinely been considered to be a tolerable abnormality with little clinical consequence, the proposed study takes the innovative approach of defining hypotensive events within the…
- Trial name
- HTN (NCT01140854)
- Testing
- Lumbar spine surgery, Neurologic/neuropsychometric examinations
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obstructive Sleep Apnea, Hypertension
Isometric Hand Grip Training in Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea (OSA) is a common clinical condition, involving the development of arterial hypertension. A Meta analysis study have shown that isometric hand grip training promotes blood pressure reduction.
- Trial name
- OSA (NCT03757169)
- Testing
- Hand grip isometric contraction, Control
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- University of Pernambuco
Hypertension, Diabetes Type 2
Evaluating the Effect of Aliskiren Versus HCTZ on Coronary Flow Reserve in Hypertensive Type II Diabetics
The purpose of this study is to assess the effect of Tekturna (aliskiren), in combination with an ACE and calcium channel blocker in hypertensive patients diagnosed with Type II diabetes.
- Trial name
- NCT00994253
- Testing
- Aliskiren, Hydrochlorothiazide
- Where
- United States
- Sponsor
- Corewell Health East
Venous Thromboembolism, Pulmonary Embolism
Timing of Venous Thromboembolism Prophylaxis in Patients With Hypertensive Intracerebral Hemorrhage
The objective of this randomized clinical trial is to evaluate the safety and efficiency of different anticoagulation schemes with heparin for venous thromboembolism prevention in patients with hypertensive intracerebral…
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, Intracerebral Hemorrhage, Deep Vein Thrombosis
- Trial name
- NCT06753786
- Testing
- Venous thromboembolism prophylaxis with unfractionated heparin or low molecular weight heparin starting within the first 2 days but not earlier than 12 hours after a hospital admission., Venous thromboembolism prophylaxis with unfractionated heparin or low molecular weight heparin starting on the 3rd day after a hospital admission.
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Pirogov Russian National Research Medical University
Lignocaine, Hypertensive Patients
Preoperative Nebulized Lignocaine Versus Nebulized Dexmedetomidine for Blunting the Pressor Response to Laryngoscopy and Intubation in Controlled Hypertensive Patients
This study aims to compare the efficacy of preoperative nebulized lignocaine versus nebulized dexmedetomidine for blunting the pressor response to laryngoscopy and intubation in patients with controlled hypertension under medical…
- Conditions
- Lignocaine, Hypertensive Patients, Dexmedetomidine, Laryngoscopy
- Trial name
- NCT07897578
- Testing
- Group D (Dexmedetomidine), Group L (Lignocaine)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Glaucoma, Ocular Hypertensive
Comparison of Efficacy and Ocular Surface Assessment Between BRIDIN-plus and Combigan in Glaucoma or Ocular Hypertensive
Comparison of Efficacy and Ocular Surface Disease Assessment between BRIDIN-plus Eye drops and Combigan Eye drops in Glaucoma or Ocular Hypertensive Patients : Phase 4, Parallel Group Design, Investigator-blind, Active-control…
- Trial name
- BCT (NCT06078592)
- Testing
- BRIDIN-plus Eye drops, Combigan Eye drops
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- CHA University
Hypertension
Impact of an IT-Based and Healthcare Professional Support Program on Patients With High Blood Pressure
The study is a randomised controlled trial to evaluate the impact of a program using information technology (IT) and healthcare professional support in patients with high blood pressure (BP) compared to usual care.
- Trial name
- NCT00374829
- Testing
- An IT-based patient follow-up and reminder system
- Where
- Canada
- Volunteers
- 223 people
- Sponsor
- Université de Montréal
Medication Adherence, Adherence, Treatment
mHealth App Intervention to Improve Medication Adherence
It is a parallel-design, two-arm, randomized controlled trial designed to assess the effectiveness of mHealth application using 7- items, multifaceted educational and reminder module intervention( written message, voice message…
- Trial name
- NCT04577157
- Testing
- mHealth using"WhatsApp" multifaceted educational and reminder module intervention to improve adherence
- Where
- Pakistan
- Volunteers
- 440 people
- Sponsor
- Universiti Putra Malaysia
Hypertension
A Randomized Controlled Trial for Hypertension Control by Integrating Cloud BP System and CPOE
Importance: Less than fifty percent of patients with hypertensive disease manage to maintain their blood pressure (BP) within normal levels.
- Trial name
- NCT02175511
- Testing
- Cloud-based home BP monitoring
- Volunteers
- 382 people
- Sponsor
- Taipei Medical University
Hypertension
A Study to Evaluate the Combination of Valsartan and Amlodipine in Hypertensive Patients Not Controlled on Monotherapy
This study is designed to provide additional efficacy and safety data for a treatment strategy based on the combination valsartan with amlodipine in hypertensive patients previously treated with monotherapy and remaining…
- Trial name
- NCT00327145
- Testing
- valsartan, hydrochlorothiazide, amlodipine
- Where
- Switzerland
- Volunteers
- 894 people
- Sponsor
- Novartis
Hypertension
Systolic Pressure Efficacy and Safety Trial of Alagebrium (SPECTRA)
This study comprises a 3- to 6-week hydrochlorothiazide run in phase, followed by a 12 week double-blind treatment phase, followed by a 2 week single-blind follow-up hydrochlorothiazide treatment phase.
- Trial name
- NCT00089713
- Testing
- alagebrium chloride (ALT-711)
- Where
- United States
- Volunteers
- 392 people
- Sponsor
- Synvista Therapeutics, Inc
Hypertension, Cardiovascular Diseases
OlmeSartan and Calcium Antagonists Randomized (OSCAR) Study
The purpose of this study is to investigate whether high-dose angiotensin II receptor blocker (ARB) monotherapy or combination therapy with ARB and calcium channel blockers is more effective in reducing the incidence of…
- Trial name
- NCT00134160
- Testing
- Olmesartan medoxomil, Calcium channel blockers (amlodipine, azelnidipine)
- Where
- 2 sites in Japan
- Volunteers
- 1,000 people
- Sponsor
- OSCAR Study
Essential Hypertension
Antihypertensive Effect of Rostafuroxin Compared With Losartan in Hypertensive Patients Bearing Specified Gene Mutations
The principal aim of the study is to demonstrate that Rostafuroxin is able to induce a more pronounced reduction of arterial blood pressure respect to Losartan, in hypertensive patients carrying at least one of the pre-specified…
- Trial name
- NCT01320397
- Testing
- Rostafuroxin, Losartan
- Where
- 26 sites in Ireland, Italy and 1 more
- Volunteers
- 240 people
- Sponsor
- RostaQuo S.p.A.
Hypertensive Patients
Pharmacometric Modeling of a Hospital Preparation
Pediatric prescribers are very often faced with a lack of suitable therapies, particularly oral ones. This represents a major public health problem and necessitates adjustments to dosage or pharmaceutical form using medications…
- Trial name
- PEDIATENS (NCT07372560)
- Testing
- Evaluation of the pharmacokinetic parameters of an oral formulation of nicardipine hydrochloride
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Rouen
Hypertension
Observational Cohort Study Evaluating the Effectiveness of an Educational Program (NGAYDAUTIEN) in Combination With Perindopril and Amlodipine Single-Pill Combination in Hypertensive Patients naïve of Antihypertensive Treatments.
The primary objective is to assess the change of systolic blood pressure from baseline after a 6-month follow up for hypertensive patients initiating Viacoram® plus an educational program (NGAYDAUTIEN) in comparison to…
- Trial name
- EDUHYPER (NCT06704815)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Servier Affaires Médicales
High Risk Hypertensive Patients
Study to Improve Quality of Care and Patient Health in the Field of Cardiovascular Risk Factors in General Practice
Observational studies performed in France and abroad in hypertensive patients at high cardiovascular risk have shown a wide gap between the therapeutic targets reached in ambulatory patients and those set by guidelines.
- Trial name
- ESCAPE (NCT00348855)
- Testing
- Cardiovascular drugs strategies, Compliance, Exercise
- Where
- 2 sites in France
- Volunteers
- 1,836 people
- Sponsor
- Collège National des Généralistes Enseignants