Clinical trials: Hypertensive Patients
Hypertension
Assessment of Anesthetic Efficacy and Hemodynamic Stability of Two LA Drugs for Hypertensive Patients
Pain control in dentistry is an important factor for reducing the fear and anxiety associated with dental procedures. For tooth extraction, it is mandatory to use resources to manage pain and discomfort such as adequate…
- Trial name
- NCT06927726
- Testing
- 4% Articaine HCL With 1:100,000 Epinephrine, 3% plain mepivacaine HCL
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Periodontal Diseases, Gingivitis
Periodontal Management in Hypertensive Patients (PERIOTENSION Trial I)
Treated hypertensive patients with any form of periodontal diseases will be randomized to either supragingival dental plaque removal using electric toothbrushes at home or intensive professional oral hygiene treatment and the…
- Conditions
- Periodontal Diseases, Gingivitis, Hypertension
- Trial name
- PERIOTENSION (NCT04328389)
- Testing
- electric toothbrush, Professional oral hygiene
- Volunteers
- 100 people
- Sponsor
- University of L'Aquila
Hypertension, Erectile Dysfunction
EECP for Erectile Dysfunction in Elderly Hypertensive Patients
Hypertension and erectile dysfunction are common health problems in older men and may share vascular dysfunction as an underlying mechanism.
- Trial name
- NCT07831551
- Testing
- Enhanced External Counterpulsation
- Where
- 2 sites in China
- Volunteers
- 106 people
- Sponsor
- Qilu Hospital of Shandong University
Hypertension
A Clinical Trial to Evaluate the Blood Pressure Lowering Effect of a Candemore Plus Tab Versus Cantabell Tab in Hypertensive Patients Inadequately Controlled by Candesartan Monotherapy
Phase 4 clinical trial to Evaluate the blood pressure lowering effect of a Candesartan/Hydrochlorothiazide(Candemore Plus Tab) versus Candesartan/Amlodipine(Cantabell Tab) in Hypertensive Patients
- Trial name
- NCT04521023
- Testing
- Cantabell Tab, Candemore Plus Tab
- Where
- 14 sites in South Korea
- Volunteers
- 132 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertension
Effect of Different Antihypertensive Treatment on Serum Uric Acid in Newly Diagnosed Hypertensive Patients
Assessment of the influence of different antihypertensive drugs on serum uric acid in newly diagnosed hypertension patients.
- Trial name
- NCT04554069
- Volunteers
- 280 people
- Sponsor
- Assiut University
Diabetes, Hypertension
Adherence and Intensification of Medications (AIM) Implementation Study
Background: Good blood pressure (BP) control among patients with diabetes is essential in preventing diabetes complications and has been found to be not only cost-effective but cost-saving.
- Trial name
- NCT00495794
- Testing
- Clinical pharmacist-based intervention
- Where
- United States
- Volunteers
- 4,622 people
- Sponsor
- US Department of Veterans Affairs
Hypertension
Safety and Efficacy of Valsartan vs Atenolol and Hydrochlorothiazide Combination on Blood Flow in Hypertensive Patients
This study evaluated the effect of valsartan on small vessel blood flow in patients with mild-to-moderate hypertension in direct comparison to atenolol and hydrochlorothiazide.
- Trial name
- NCT00396656
- Testing
- Atenolol, Hydrochlorothiazide (HCTZ)), Valsartan
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 30 people
- Sponsor
- Novartis
Effect of Drug
Comparison of Preserved and Preservative-free Latanoprost 0.005% in Primary Open Angle Glaucoma and Ocular Hypertensive Patients, at Guinness Eye Centre, Lagos.
It is a randomised, double-blinded clinical trial in which consenting participants who meet the inclusion criteria would be randomised into 2 groups.
- Trial name
- NCT05606796
- Testing
- Latanoprost 0.005% Ophthalmic Solution
- Where
- Nigeria
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Uzoma Chinyei Joan
Primary Hypertension
Efficacy Observational Study of Candesartan Cilexetil on Hypertensive Patients
The purpose of this study is to observe treatment with candesartan cilexetil 16mg for 8 weeks, in uncontrolled hypertensive patients, in improvement of achieving of treatment goals and impact on blood pressure level in patients…
- Trial name
- NCT00573742
- Testing
- Candesartan Cilexeotil 16mg
- Where
- 16 sites in Romania
- Volunteers
- 1,940 people
- Sponsor
- AstraZeneca
Arterial Hypertension, Resistant Hypertension
Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity.
- Conditions
- Arterial Hypertension, Resistant Hypertension, Microvascular Function, Nitrate Supplementation
- Trial name
- NCT06169241
- Testing
- Beetroot extract
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Hypertension
A Randomised, Parallel-group, Double-blind, Double-dummy Study to Compare the Effects of Lacidipine Versus Bendrofluazide on Markers of Platelet Activation and Haemorheological Factors in Hypertensive Patients
The aim of this study is to compare the effects of lacidipine on markers of platelet activation and other rheological factors in hypertensive patients with those of bendrofluazide
- Trial name
- NCT02235402
- Testing
- Lacidipine, Bendrofluazide
- Volunteers
- 26 people
- Sponsor
- Boehringer Ingelheim
Hypertension
Novel Evaluation With QGC001 in Hypertensive Overweight Patients of Multiple Ethnic Origins
Essential hypertension (HTN) is a disease that affects approximately 1 billion individuals worldwide. Despite the availability of effective and safe anti-hypertensive drugs, 65% of subjects diagnosed with HTN do not have their…
- Trial name
- NEW-HOPE (NCT03198793)
- Testing
- QGC001
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Quantum Genomics SA
Obesity, Heart Disease
Weight Loss in Pre-Hypertensive Patients With Diastolic Dysfunction
The focus of this study is to observe the impact of weight loss in overweight individuals who have pre-hypertension (have a blood pressure reading of 121-139/81-89 mm Hg).
- Conditions
- Obesity, Heart Disease, Weight Loss, Diastolic Dysfunction
- Trial name
- NCT00911209
- Testing
- Dietitian counselling
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Ragavendra Baliga
Hypertensive Retinopathy
Non-invasive Measurement of Retinal Blood Flow Based on Vessel Analysis and Fourier Domain Optical Coherence Tomography in Patients With Hypertensive Retinopathy
Recently, a new and sophisticated method for assessment of retinal blood flow and retinal blood flow velocity profiles has become available.
- Trial name
- NCT01753648
- Testing
- Dynamic Vessel Analyzer, FDOCT, Ocular perfusion pressure
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Hypertension
Telmisartan 80mg+Hydrochlorothiazide (HCTZ) 25 mg in Hypertension: an Observational Study
It is a national, retrospective , observational study in hypertensive patients treated for at least 8 weeks with the fixed dose combination of telmisartan 80 mg and hydrochlorothiazide 25 mg.
- Trial name
- NCT00909038
- Where
- 915 sites in France
- Volunteers
- 2,411 people
- Sponsor
- Boehringer Ingelheim
Hypertension
A Study to Describe Vascular and Renal Effects and Safety of Valsartan in Patients With High Blood Pressure
One hundred twenty patients with arterial hypertension and albuminuria (some amount of albumin in urine) are given valsartan 80 mg and then160 mg to normalize blood pressure.
- Trial name
- NCT00171353
- Testing
- valsartan
- Where
- Switzerland
- Volunteers
- 109 people
- Sponsor
- Novartis
Hypertension
Comparison of Breathing Exercise for Hypertensive Patients
To determine the Effectiveness of diaphragmatic breathing vs. slow breathing techniques on blood pressure and Quality of life in adults with stage 1 hypertension.
- Trial name
- NCT05158569
- Testing
- Slow breathing exercise group, Diaphragmatic breathing exercise group
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Hypertension
Water-only Fasting in the Treatment of Hypertension Patients
This purpose of this study is to examine the safety and feasibility of water-only fasting to treat hypertensive patients.
- Trial name
- NCT04515095
- Testing
- Water-only Fasting
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- TrueNorth Health Foundation
Pre-Eclampsia, IUGR
Fetal Doppler Indices in Predicting Perinatal Outcome Among Severely Hypertensive Pregnant Patients.
60 pregnant women with singleton living fetus between 34 -38 wks gestation known to have severe hypertension in the current pregnancy were included.
- Trial name
- NCT03515759
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Hypertension
An Assessment of Long Term Safety of the Combination of Aliskiren / Amlodipine in Patients With High Blood Pressure
To assess the long-term (6 month and 12 month) safety of the combination of aliskiren 300 mg / amlodipine 10 mg in patients with essential hypertension (Mean Sitting Diastolic Blood Pressure [msDBP] ≥ 90 mmHg and < 110 mmHg).
- Trial name
- NCT00402103
- Testing
- Aliskiren, Amlodipine, Hydrochlorothiazide
- Where
- 8 sites in United States, Belgium and 6 more
- Volunteers
- 556 people
- Sponsor
- Novartis