Clinical trials: Hyperthyroidism
Thyroid Eye Disease
Study to Assess Batoclimab in Participants With Active Thyroid Eye Disease
To evaluate the efficacy of batoclimab 680 milligrams (mg) subcutaneous (SC) once a week (QW) for 12 weeks followed by 340 mg SC QW for 12 weeks versus placebo on proptosis responder rate at Week 24.
- Trial name
- NCT05524571
- Testing
- Batoclimab
- Where
- 45 sites in United States, Australia and 9 more
- Volunteers
- 86 people
- Sponsor
- Immunovant Sciences GmbH
Hyperthyroidism, Cardiovascular Diseases
Follow-up Study of the RAI-Treated Hyperthyroid Patients
Previous studies of hyperthyroid patients suggest that they remain at increased risk of cardiovascular morbidity after restoring euthyroidism.
- Conditions
- Hyperthyroidism, Cardiovascular Diseases, Atrial Fibrillation
- Trial name
- NCT00471458
- Where
- Finland
- Volunteers
- 5,222 people
- Sponsor
- Tampere University
Thyroid Eye Disease
A Study of IBI3031 in Participants With Thyroid Eye Disease
This is a multicenter, randomized, double-masked, placebo-controlled, single/multiple-dose-escalation trial conducted in Chinese participants with Thyroid Eye Disease (TED), aiming to evaluate the safety and tolerability of…
- Trial name
- NCT07622368
- Testing
- IBI3031
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Thyroid Eye Disease (TED)
A Safety and Tolerability Study of VRDN-003 in Participants With Thyroid Eye Disease (TED)
This is a clinical trial assessing the safety and tolerability of an investigational drug, VRDN-003, in participants with Thyroid Eye Disease (TED).
- Trial name
- NCT06812325
- Testing
- VRDN-003
- Where
- 64 sites in United States, France and 5 more
- Volunteers
- 320 people
- Sponsor
- Viridian Therapeutics, Inc.
Age-Related Macular Degeneration, Allergies
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and…
- Conditions
- Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease
- Trial name
- NCT05635266
- Testing
- Specimen sample
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Graves Disease, Mental Fatigue
Validating Immunological Markers Associated With Mental Fatigue in Graves' Disease
Mental fatigue occurs in many diseases and the reasons are mostly unknown. The investigators hypothesize that remaining mental fatigue after restored euthyroidism in Graves' disease is an autoimmune complication.
- Trial name
- NCT06081439
- Where
- Sweden
- Volunteers
- 430 people
- Sponsor
- Vastra Gotaland Region
Graves' Disease
Early Levothyroxine Post Radioactive Iodine
The study will try to answer the question of whether early treatment with levothyroxine at 4 weeks after radioactive iodine for Graves'disease will prevent overt hypothyroidism (low thyroid hormone levels).
- Trial name
- NCT01950260
- Testing
- Levothyroxine
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Mayo Clinic
Graves' Disease
Graves' Disease Remission Study: MycoMeth Combo
A randomized study to evaluate the efficacy and safety of combining mycophenolate mofetil with methimazole in patients with newly diagnosed Graves' disease.
- Trial name
- 3M-RGD (NCT06068179)
- Testing
- Mycophenolate Mofetil, Oral, 250 Mg, methimazole, oral, 10mg
- Where
- China
- Volunteers
- 205 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Graves Disease, Hyperthyroidism
Iodine Supplementation in Graves' Hyperthyroidism
In China, the morbidity of thyroid diseases is high and the harm is serious. Iodine is closely related to thyroid diseases. It should be paid attention to guide patients to supplement iodine scientifically.
- Trial name
- NCT06540469
- Testing
- Iodine Supplementation in Whole Course of Treatment with ATDs, Iodine Supplementation During Maintenance Treatment with ATDs, Iodine Restriction in Whole Course of Treatment with ATDs
- Volunteers
- 315 people
- Sponsor
- Shandong Provincial Hospital
Hyperthyroidism
Postoperative Hyperthyroidism
The purpose of this study is to evaluate the frequency and the clinical course of postoperative hyperthyroidism following surgery of tertiary hyperparathyroidism (THP) and to determine the diagnostic value of thyroglobulin in…
- Trial name
- NCT01095341
- Testing
- No intervention performed
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- Heidelberg University
Thyroid Associated Ophthalmopathy
Combination of Orbital Compression Surgery and Strabismus Surgery for Thyroid Associated Ophthalmopathy
The purpose of this study is to determine whether combination of orbital compression surgery with strabismus surgery is better than strabismus surgery after orbital compression surgery in the treatment of moderate-to-severe…
- Trial name
- NCT04919694
- Testing
- combination of orbital compression surgery and strabismus surgery, orbital compression
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sun Yat-sen University
All-Cause Mortality, Circulatory and Other Disease Mortality
Hyperthyroid Follow-Up Study
Background: Hyperthyroidism is a common disease. It is very common for women. It is usually treated with Radioiodine (I-131). Some people think that this might cause cancer, even many years later.
- Conditions
- All-Cause Mortality, Circulatory and Other Disease Mortality, Thyroid and Other Cancer Mortality
- Trial name
- NCT02989103
- Where
- United States
- Volunteers
- 35,593 people
- Sponsor
- National Cancer Institute (NCI)